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The map label for this gene is barA [H]

Identifier: 170078867

GI number: 170078867

Start: 2351673

End: 2353568

Strand: Reverse

Name: barA [H]

Synonym: SYNPCC7002_A2271

Alternate gene names: 170078867

Gene position: 2353568-2351673 (Counterclockwise)

Preceding gene: 170078868

Following gene: 170078865

Centisome position: 78.24

GC content: 49.89

Gene sequence:

>1896_bases
ATGGTTTTGTCGTCATTATCTCGTTTGTCTTCCCGTTTTTTGATTCATCAACCGGAACCTTGGTGGAAGCACGTGGTCGT
GGCGATCGCCTATTGTGTTACGGCCCTGTTTTCTCACAATTTTACGGTTTACCCAGAAACAGGTTCGACGCCCATTTGGA
TTCCGGGGGGGCTAGCGGTGGGCTTCCTGGTCGTGTGGGGACTACCCATGTGGTGGGGGGTCTTGGGGGGCATTTTGGTC
GCAGAGATCGTCATTTACCAAGCCTGGCTCAGTGTGCCTAATTTGTTGATGACCCTCGGCATTACGGCGATCGCCACTGC
CGGAAAAGTCTTGGCGGCCCATTGGTTGCAAGGTCAAAATCAAAACCGCTATTTTCTAGACCGTCCGGAGACGACCCAAA
ATTTTATCCTCTACAGTTGTATCCTGAGCCACCTCCCCGTGGCGATCGCCTGTGCCCTCATCGTTTGCCTGGCCGGGAAA
GCCCCTTGGTCGCTATACCCAGAAATTGCTGGGACTTGGTTTCTCAGCGACAGCTTTGGCATTCTCATTTTCGCGCCTCT
GATTATTGCCACCCAGCATGGCTACCGTGAATTTATCCATCACCTCAAAAAATATTGGTTAGCGGCCATCAGCATCGCCA
CCCTGACCCTCGGCATTAGTCACCTGGTGATCAACGGCTACCACGGTGAATATCTCCTTGCCCCTCTCCTGGTGTGGACA
ACCTTTCAGTTTAAAGAAGTTGGCGCAACACTCCTGATGGTGATGATCGTTTTGATGGTGGCGATTAGCACTGTCCAGGG
CTATGGCACCTTTGTGGGGGAGTCGTTACGTAATTCCCTACTGCTCTCGCAATTTTTTATTGCCTGCATTGGCCTGATGA
CGTTGATGTTGATTGCGGTACTAAACGAAAAAAAGCAAGCCAAAGCCGATCTCAAGGCGATGAATCAAACCCTTGCCAGC
CAAAATCAACGCCTCGAAGAGCTGGCGACCCAGAAAGAATTGGCCCATCAGCAGCGGGAAAATCTCCTGGTTAAATATAA
TCAAGCCCTGAAACGACAACTAAACCTTATCCAAGCTAAACAAGCCGCAGAAATGGCGGCCCAGGAAAAGAGTGAATTTC
TCGCCAACATGAGCCACGAGATTCGCACGCCCCTAAATGGGGTGATTGGTGTGGCCCAATTGCTACTGACTATGGATCTC
AAGGACGATCAAGCAGAATTGGTCGCCATTATTGAAGACAGTGGTAAAACCCTACTGAATATCATCAACGATATCCTTGA
TTTTCTCCGCATTGAGTCGGGCAGCCTCCGGTTAGAAGCCCGTTGTTTTTCGTTTCAGGAACTGTTGAAATCTGTCTTCA
CCCTCCTGAAAGTACAGGCCGACCAAAAGGATATTGATTTGCAATATTGTGTGGCGGATTCGATTCCCAATATTTTGATG
GGGGATGATCTACGGCTGCGGCAAATTTTGTTTAACCTTTTGGGTAATGCCCTCAAATTTACGGCAACGGGATCTGTGCA
ATTGGTGATCACAAGCCACACGGTGCCGTCCCTGAGCGACCCTCCAACGGAGGAACTGAGTTTTCAAATTTTAGATACGG
GTATTGGCATTCAGGTTGCGCAACTCAATCAACTATTTCAACCCTTTATCCAGGCTGATGCTTCCATTAGTCGTCGCTAC
GGGGGTAGTGGCTTAGGGTTGGCGATCGCCAAACGTCTGGTGAATCTCATGGGCGGCAAAATTTGGGTTGAGAGCAATGG
TGAACTGGCCGGTGATCCACCGCCAGACTGGTTTACCCCCGGTGAACTCGATCCCCAGAGTTATGGTGCTTCTTTTTACT
TTACGTTTTTGAGCCATCCCGTCTCGGAGCTAGATGGTGCTCCCAACCCAAATTGA

Upstream 100 bases:

>100_bases
TTAGAGATTCATTGCATAGGTGTCATGAACGATTCAAGCACACCCCACAATAGAATCTAGTCATCGGTAGCCAATTATTT
TCCCTAATCTTTTCTCTGTG

Downstream 100 bases:

>100_bases
ACGAGCGAGCGGGCTAATTACGCGGAGTGGAGTAGGGGAGCCGCGCCCAGGAGTTTTTGGGTGTAAGGGTGTTGGGGATG
ATTGAAAATATCAACGGTTT

Product: hybrid sensory kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MVLSSLSRLSSRFLIHQPEPWWKHVVVAIAYCVTALFSHNFTVYPETGSTPIWIPGGLAVGFLVVWGLPMWWGVLGGILV
AEIVIYQAWLSVPNLLMTLGITAIATAGKVLAAHWLQGQNQNRYFLDRPETTQNFILYSCILSHLPVAIACALIVCLAGK
APWSLYPEIAGTWFLSDSFGILIFAPLIIATQHGYREFIHHLKKYWLAAISIATLTLGISHLVINGYHGEYLLAPLLVWT
TFQFKEVGATLLMVMIVLMVAISTVQGYGTFVGESLRNSLLLSQFFIACIGLMTLMLIAVLNEKKQAKADLKAMNQTLAS
QNQRLEELATQKELAHQQRENLLVKYNQALKRQLNLIQAKQAAEMAAQEKSEFLANMSHEIRTPLNGVIGVAQLLLTMDL
KDDQAELVAIIEDSGKTLLNIINDILDFLRIESGSLRLEARCFSFQELLKSVFTLLKVQADQKDIDLQYCVADSIPNILM
GDDLRLRQILFNLLGNALKFTATGSVQLVITSHTVPSLSDPPTEELSFQILDTGIGIQVAQLNQLFQPFIQADASISRRY
GGSGLGLAIAKRLVNLMGGKIWVESNGELAGDPPPDWFTPGELDPQSYGASFYFTFLSHPVSELDGAPNPN

Sequences:

>Translated_631_residues
MVLSSLSRLSSRFLIHQPEPWWKHVVVAIAYCVTALFSHNFTVYPETGSTPIWIPGGLAVGFLVVWGLPMWWGVLGGILV
AEIVIYQAWLSVPNLLMTLGITAIATAGKVLAAHWLQGQNQNRYFLDRPETTQNFILYSCILSHLPVAIACALIVCLAGK
APWSLYPEIAGTWFLSDSFGILIFAPLIIATQHGYREFIHHLKKYWLAAISIATLTLGISHLVINGYHGEYLLAPLLVWT
TFQFKEVGATLLMVMIVLMVAISTVQGYGTFVGESLRNSLLLSQFFIACIGLMTLMLIAVLNEKKQAKADLKAMNQTLAS
QNQRLEELATQKELAHQQRENLLVKYNQALKRQLNLIQAKQAAEMAAQEKSEFLANMSHEIRTPLNGVIGVAQLLLTMDL
KDDQAELVAIIEDSGKTLLNIINDILDFLRIESGSLRLEARCFSFQELLKSVFTLLKVQADQKDIDLQYCVADSIPNILM
GDDLRLRQILFNLLGNALKFTATGSVQLVITSHTVPSLSDPPTEELSFQILDTGIGIQVAQLNQLFQPFIQADASISRRY
GGSGLGLAIAKRLVNLMGGKIWVESNGELAGDPPPDWFTPGELDPQSYGASFYFTFLSHPVSELDGAPNPN
>Mature_631_residues
MVLSSLSRLSSRFLIHQPEPWWKHVVVAIAYCVTALFSHNFTVYPETGSTPIWIPGGLAVGFLVVWGLPMWWGVLGGILV
AEIVIYQAWLSVPNLLMTLGITAIATAGKVLAAHWLQGQNQNRYFLDRPETTQNFILYSCILSHLPVAIACALIVCLAGK
APWSLYPEIAGTWFLSDSFGILIFAPLIIATQHGYREFIHHLKKYWLAAISIATLTLGISHLVINGYHGEYLLAPLLVWT
TFQFKEVGATLLMVMIVLMVAISTVQGYGTFVGESLRNSLLLSQFFIACIGLMTLMLIAVLNEKKQAKADLKAMNQTLAS
QNQRLEELATQKELAHQQRENLLVKYNQALKRQLNLIQAKQAAEMAAQEKSEFLANMSHEIRTPLNGVIGVAQLLLTMDL
KDDQAELVAIIEDSGKTLLNIINDILDFLRIESGSLRLEARCFSFQELLKSVFTLLKVQADQKDIDLQYCVADSIPNILM
GDDLRLRQILFNLLGNALKFTATGSVQLVITSHTVPSLSDPPTEELSFQILDTGIGIQVAQLNQLFQPFIQADASISRRY
GGSGLGLAIAKRLVNLMGGKIWVESNGELAGDPPPDWFTPGELDPQSYGASFYFTFLSHPVSELDGAPNPN

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: COG3447

COG function: function code T; Predicted integral membrane sensor domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=44.6153846153846, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=39.344262295082, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=38.1481481481481, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=34.6491228070175, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=33.8775510204082, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786783, Length=316, Percent_Identity=24.3670886075949, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=30.1369863013699, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=27.7992277992278, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=26.2008733624454, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=25.3218884120172, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=24.3589743589744, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322044, Length=68, Percent_Identity=42.6470588235294, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69736; Mature: 69736

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSSLSRLSSRFLIHQPEPWWKHVVVAIAYCVTALFSHNFTVYPETGSTPIWIPGGLAV
CCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEECCHHHH
GFLVVWGLPMWWGVLGGILVAEIVIYQAWLSVPNLLMTLGITAIATAGKVLAAHWLQGQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QNRYFLDRPETTQNFILYSCILSHLPVAIACALIVCLAGKAPWSLYPEIAGTWFLSDSFG
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEECCCCC
ILIFAPLIIATQHGYREFIHHLKKYWLAAISIATLTLGISHLVINGYHGEYLLAPLLVWT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
TFQFKEVGATLLMVMIVLMVAISTVQGYGTFVGESLRNSLLLSQFFIACIGLMTLMLIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNEKKQAKADLKAMNQTLASQNQRLEELATQKELAHQQRENLLVKYNQALKRQLNLIQAK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAEMAAQEKSEFLANMSHEIRTPLNGVIGVAQLLLTMDLKDDQAELVAIIEDSGKTLLN
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHH
IINDILDFLRIESGSLRLEARCFSFQELLKSVFTLLKVQADQKDIDLQYCVADSIPNILM
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEHHCCCCCCC
GDDLRLRQILFNLLGNALKFTATGSVQLVITSHTVPSLSDPPTEELSFQILDTGIGIQVA
CCCHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCCCCCCHHHEEEEEECCCCEEHH
QLNQLFQPFIQADASISRRYGGSGLGLAIAKRLVNLMGGKIWVESNGELAGDPPPDWFTP
HHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCC
GELDPQSYGASFYFTFLSHPVSELDGAPNPN
CCCCHHHCCCHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure
MVLSSLSRLSSRFLIHQPEPWWKHVVVAIAYCVTALFSHNFTVYPETGSTPIWIPGGLAV
CCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEECCHHHH
GFLVVWGLPMWWGVLGGILVAEIVIYQAWLSVPNLLMTLGITAIATAGKVLAAHWLQGQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QNRYFLDRPETTQNFILYSCILSHLPVAIACALIVCLAGKAPWSLYPEIAGTWFLSDSFG
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEECCCCC
ILIFAPLIIATQHGYREFIHHLKKYWLAAISIATLTLGISHLVINGYHGEYLLAPLLVWT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
TFQFKEVGATLLMVMIVLMVAISTVQGYGTFVGESLRNSLLLSQFFIACIGLMTLMLIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNEKKQAKADLKAMNQTLASQNQRLEELATQKELAHQQRENLLVKYNQALKRQLNLIQAK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAEMAAQEKSEFLANMSHEIRTPLNGVIGVAQLLLTMDLKDDQAELVAIIEDSGKTLLN
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHH
IINDILDFLRIESGSLRLEARCFSFQELLKSVFTLLKVQADQKDIDLQYCVADSIPNILM
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEHHCCCCCCC
GDDLRLRQILFNLLGNALKFTATGSVQLVITSHTVPSLSDPPTEELSFQILDTGIGIQVA
CCCHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCCCCCCHHHEEEEEECCCCEEHH
QLNQLFQPFIQADASISRRYGGSGLGLAIAKRLVNLMGGKIWVESNGELAGDPPPDWFTP
HHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCC
GELDPQSYGASFYFTFLSHPVSELDGAPNPN
CCCCHHHCCCHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]