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The map label for this gene is ahcY [H]

Identifier: 170078673

GI number: 170078673

Start: 2151091

End: 2152467

Strand: Direct

Name: ahcY [H]

Synonym: SYNPCC7002_A2069

Alternate gene names: 170078673

Gene position: 2151091-2152467 (Clockwise)

Preceding gene: 170078660

Following gene: 170078675

Centisome position: 71.51

GC content: 51.56

Gene sequence:

>1377_bases
ATGAGCACTTCAACCCTCACCCGTGACTACAAGGTCGCCGATATTAATTTGGCAAGCTGGGGCCGCAAGGAAATTGCGAT
CGCCGAAGGCGAAATGCCCGCCCTCATGACCATCCGGAAAAAATACAGTGCAAGCAAGCCCTTAGCTGGGGCAAAGATTA
TTGGCTGTATCCACATGACCATTCAGACGGCGGTGCTGATTGAAACCCTGGTCGAACTGGGGGCCGAAGTGCGTTGGTCA
TCCTGTAATATTTTCTCTACCCAAGACCATGCCGCAGCGGCGATCGCCGAGGCAGGCGTACCCGTTTTCGCGTGGAAAGG
GGAAACCGAAGAAGAATACATGTGGTGTATTGAGCAGACCTGTCGCACCCCTGACGGCGAACTTTGGGATGCCAACATGA
TCCTCGACGATGGTGGTGACCTGACGGGCTACATCCACACTACCTATCCTGAAATGCTCTCCCGCATCCATGGCGTCACC
GAAGAGACCACCACTGGCGTCCATCGTCTCTACGAAATGCTCGAAAAGGGCAAACTAAAAATCCCCGCCATTAACGTTAA
TGACTCCGTTACCAAGGCGAAAAACGACAACAAGTATGGGTGCCGCCACAGCTTAAACGATGCGATTAAACGCGCCACTG
ACCACCTCCTCGCCGGGAAAAAAGCCCTGGTGATTGGGTATGGCGATGTGGGCAAAGGCTCGGCTGCGTCTCTCCGTCAG
GAAGGCATGATTGTCAAGGTCACTGAAGTTGACCCCATCTGCGCGATGCAGGCTTGTATGGATGGATTTGAAGTGGTTTC
ACCCTTCATTAACGGCATCAACAATGGGCCAGAGAGCATCAATAAAGATCTCTTAGCGAATACGGATCTCTTGGTGACGG
CCACCGGTAACTTTAATGTTTGCGATGCCAATATGCTTGCTGCCCTGAAGCCCAGTGCAGTGGTTTGCAACATTGGTCAC
TTCGATAATGAGATTGACACTGCTTACATGCGGAAAAACTGGCAGTGGGAAGAAATCAAGCCCCAAGTTCATAAGGTTTA
TCGCAGTGATGATCCCCAGGACTTTTTGATTCTCTTAGCGGAAGGTCGTTTGGTCAACCTGGGGAATGCGACAGGGCACC
CCTCCCGGATTATGGATGGTTCGTTTGCTAACCAAGTTCTCGCGCAAATGTTCTTGTTTGAGCGTCAGTTTGCCAACCAA
GATCCCAGTGAACGCAAGATTACGGTTGAGGTGTTACCGAAGCATCTTGATGAGGAAGTGGCCCGCTACATGGTGCAAGG
TTTTGGCGGCGTGATCACCCAACTCACCCAAACCCAAGCGGATTACATCCATGTACCTGTGGCAGGGCCTTTCAAAACGG
AAAGCTACAAGTACTAA

Upstream 100 bases:

>100_bases
ATGCGAGCGAGTGGCATGATTACCGGATCGATATATTTCTAGATCAGCCACAATATATTTTTAATCACCTTTCTCTGGAC
ATTAACTCAACAGCAAAACT

Downstream 100 bases:

>100_bases
AGCTTGATTTCTTTTTAACTTGAATAAACATGACAGGGGTTGATCTGGGTCAACCCTTTTTTGATGGCGGGTTTTAACCT
AAAAATGTATTGATCACTTT

Product: S-adenosyl-L-homocysteine hydrolase

Products: NA

Alternate protein names: S-adenosyl-L-homocysteine hydrolase; AdoHcyase [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSTSTLTRDYKVADINLASWGRKEIAIAEGEMPALMTIRKKYSASKPLAGAKIIGCIHMTIQTAVLIETLVELGAEVRWS
SCNIFSTQDHAAAAIAEAGVPVFAWKGETEEEYMWCIEQTCRTPDGELWDANMILDDGGDLTGYIHTTYPEMLSRIHGVT
EETTTGVHRLYEMLEKGKLKIPAINVNDSVTKAKNDNKYGCRHSLNDAIKRATDHLLAGKKALVIGYGDVGKGSAASLRQ
EGMIVKVTEVDPICAMQACMDGFEVVSPFINGINNGPESINKDLLANTDLLVTATGNFNVCDANMLAALKPSAVVCNIGH
FDNEIDTAYMRKNWQWEEIKPQVHKVYRSDDPQDFLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQMFLFERQFANQ
DPSERKITVEVLPKHLDEEVARYMVQGFGGVITQLTQTQADYIHVPVAGPFKTESYKY

Sequences:

>Translated_458_residues
MSTSTLTRDYKVADINLASWGRKEIAIAEGEMPALMTIRKKYSASKPLAGAKIIGCIHMTIQTAVLIETLVELGAEVRWS
SCNIFSTQDHAAAAIAEAGVPVFAWKGETEEEYMWCIEQTCRTPDGELWDANMILDDGGDLTGYIHTTYPEMLSRIHGVT
EETTTGVHRLYEMLEKGKLKIPAINVNDSVTKAKNDNKYGCRHSLNDAIKRATDHLLAGKKALVIGYGDVGKGSAASLRQ
EGMIVKVTEVDPICAMQACMDGFEVVSPFINGINNGPESINKDLLANTDLLVTATGNFNVCDANMLAALKPSAVVCNIGH
FDNEIDTAYMRKNWQWEEIKPQVHKVYRSDDPQDFLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQMFLFERQFANQ
DPSERKITVEVLPKHLDEEVARYMVQGFGGVITQLTQTQADYIHVPVAGPFKTESYKY
>Mature_457_residues
STSTLTRDYKVADINLASWGRKEIAIAEGEMPALMTIRKKYSASKPLAGAKIIGCIHMTIQTAVLIETLVELGAEVRWSS
CNIFSTQDHAAAAIAEAGVPVFAWKGETEEEYMWCIEQTCRTPDGELWDANMILDDGGDLTGYIHTTYPEMLSRIHGVTE
ETTTGVHRLYEMLEKGKLKIPAINVNDSVTKAKNDNKYGCRHSLNDAIKRATDHLLAGKKALVIGYGDVGKGSAASLRQE
GMIVKVTEVDPICAMQACMDGFEVVSPFINGINNGPESINKDLLANTDLLVTATGNFNVCDANMLAALKPSAVVCNIGHF
DNEIDTAYMRKNWQWEEIKPQVHKVYRSDDPQDFLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQMFLFERQFANQD
PSERKITVEVLPKHLDEEVARYMVQGFGGVITQLTQTQADYIHVPVAGPFKTESYKY

Specific function: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine [H]

COG id: COG0499

COG function: function code H; S-adenosylhomocysteine hydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosylhomocysteinase family [H]

Homologues:

Organism=Homo sapiens, GI9951915, Length=450, Percent_Identity=56.2222222222222, Blast_Score=471, Evalue=1e-133,
Organism=Homo sapiens, GI239937451, Length=428, Percent_Identity=55.3738317757009, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI298286489, Length=453, Percent_Identity=47.9028697571744, Blast_Score=418, Evalue=1e-117,
Organism=Homo sapiens, GI24308043, Length=453, Percent_Identity=47.9028697571744, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI195539337, Length=453, Percent_Identity=47.9028697571744, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI195539349, Length=453, Percent_Identity=47.9028697571744, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI21361647, Length=458, Percent_Identity=47.3799126637555, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17506425, Length=450, Percent_Identity=57.5555555555556, Blast_Score=490, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6320882, Length=465, Percent_Identity=54.8387096774194, Blast_Score=470, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24642172, Length=450, Percent_Identity=56.4444444444444, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24656245, Length=454, Percent_Identity=46.9162995594714, Blast_Score=410, Evalue=1e-115,
Organism=Drosophila melanogaster, GI45553387, Length=451, Percent_Identity=46.7849223946785, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI45553385, Length=450, Percent_Identity=46.6666666666667, Blast_Score=381, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000043
- InterPro:   IPR015878
- InterPro:   IPR020082 [H]

Pfam domain/function: PF05221 AdoHcyase; PF00670 AdoHcyase_NAD [H]

EC number: =3.3.1.1 [H]

Molecular weight: Translated: 50586; Mature: 50455

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00738 ADOHCYASE_1 ; PS00739 ADOHCYASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSTLTRDYKVADINLASWGRKEIAIAEGEMPALMTIRKKYSASKPLAGAKIIGCIHMT
CCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
IQTAVLIETLVELGAEVRWSSCNIFSTQDHAAAAIAEAGVPVFAWKGETEEEYMWCIEQT
HHHHHHHHHHHHCCCCEEECCCCEECCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
CRTPDGELWDANMILDDGGDLTGYIHTTYPEMLSRIHGVTEETTTGVHRLYEMLEKGKLK
HCCCCCCEEECEEEEECCCCEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
IPAINVNDSVTKAKNDNKYGCRHSLNDAIKRATDHLLAGKKALVIGYGDVGKGSAASLRQ
EEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHH
EGMIVKVTEVDPICAMQACMDGFEVVSPFINGINNGPESINKDLLANTDLLVTATGNFNV
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHCCCCEEEEECCCCCE
CDANMLAALKPSAVVCNIGHFDNEIDTAYMRKNWQWEEIKPQVHKVYRSDDPQDFLILLA
ECCHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCHHHHCHHHHHHHCCCCCCEEEEEEE
EGRLVNLGNATGHPSRIMDGSFANQVLAQMFLFERQFANQDPSERKITVEVLPKHLDEEV
CCCEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHH
ARYMVQGFGGVITQLTQTQADYIHVPVAGPFKTESYKY
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
STSTLTRDYKVADINLASWGRKEIAIAEGEMPALMTIRKKYSASKPLAGAKIIGCIHMT
CCCCCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
IQTAVLIETLVELGAEVRWSSCNIFSTQDHAAAAIAEAGVPVFAWKGETEEEYMWCIEQT
HHHHHHHHHHHHCCCCEEECCCCEECCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
CRTPDGELWDANMILDDGGDLTGYIHTTYPEMLSRIHGVTEETTTGVHRLYEMLEKGKLK
HCCCCCCEEECEEEEECCCCEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
IPAINVNDSVTKAKNDNKYGCRHSLNDAIKRATDHLLAGKKALVIGYGDVGKGSAASLRQ
EEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHH
EGMIVKVTEVDPICAMQACMDGFEVVSPFINGINNGPESINKDLLANTDLLVTATGNFNV
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHCCCCEEEEECCCCCE
CDANMLAALKPSAVVCNIGHFDNEIDTAYMRKNWQWEEIKPQVHKVYRSDDPQDFLILLA
ECCHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCHHHHCHHHHHHHCCCCCCEEEEEEE
EGRLVNLGNATGHPSRIMDGSFANQVLAQMFLFERQFANQDPSERKITVEVLPKHLDEEV
CCCEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHH
ARYMVQGFGGVITQLTQTQADYIHVPVAGPFKTESYKY
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA