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The map label for this gene is degU [H]

Identifier: 170078560

GI number: 170078560

Start: 2036278

End: 2037033

Strand: Direct

Name: degU [H]

Synonym: SYNPCC7002_A1955

Alternate gene names: 170078560

Gene position: 2036278-2037033 (Clockwise)

Preceding gene: 170078557

Following gene: 170078562

Centisome position: 67.69

GC content: 46.16

Gene sequence:

>756_bases
ATGTATATCGATCATGCTATATTTTGGAAAGTCTCCGGGAAAACCATGAAAAAAATTCGGGTTGTTCTAATTGAAGATCA
TGATTTAACGCGCATCGGGCTAAGAACTTCTCTACAACAATGTGCGGACATTGAACTTTTAGCAGAGGCGGCCAATGGAG
CGGATGGATTGCGTTTGTTAGAAGAGATTCATCCTGATTTAGCGATTGTGGATATTGGTTTGCCTGAGCTTGACGGGATT
GAGTTGACCCGAATTTTGAAACAGGAAAAGCTCAAGGATCAGTCCCACGAGGCGCAAACAAAGGTTTTGATTTTGACGTT
GCAGGATGATGATGCCGCTGTTTTAGCAGCCTTTGCGGCAGGAGCTGATTCCTATTGTATGAAGGATATTACGTTTGATC
ACTTGGTAGAGGCGGTCAAAACGACAGACTCAGGCAACAGTTGGATTGATCCGGCGATCGCCCGCATTGTCCTCAATCAA
GTGCAAGGGGGAGAACCCCTTTCTGGCTCTACAGTTACGATTCAAGCGACTTCCCCAGAAGATCAACAACTCCTAGAAAG
CTGTCCCCTAACGGATCGAGAATTGGAAGTACTCCAATTGATTGTTGATGGTTGCAGCAACTCCGAAATTGCCGAGCATT
TATTTATCACCGTGGGTACCGTTAAAACCCATGTCCGCAATATTCTCAATAAGCTTTGTGCCGATGACCGTACCCAGGCT
GCTGTGCGTGCCCTTCGTTCTGGTCTGGTCGGTTAA

Upstream 100 bases:

>100_bases
GACCGACCATCAAGAGCAATGTAAGGAGGAGGGTCGAGGTGATTACGGATTGTTCTAACACGGTTTTTACAAGGAGGGCT
TGAAGATTCACTGCATATAA

Downstream 100 bases:

>100_bases
AAAGCGCCTTGGCGGAGATTCATCAAATTATTCAAAATGTCGCAGTTGCAAACAGATAGGACTATCCGAGTCAAAAATTA
TGCTCTAAGTTTAGGATTTC

Product: two-component response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MYIDHAIFWKVSGKTMKKIRVVLIEDHDLTRIGLRTSLQQCADIELLAEAANGADGLRLLEEIHPDLAIVDIGLPELDGI
ELTRILKQEKLKDQSHEAQTKVLILTLQDDDAAVLAAFAAGADSYCMKDITFDHLVEAVKTTDSGNSWIDPAIARIVLNQ
VQGGEPLSGSTVTIQATSPEDQQLLESCPLTDRELEVLQLIVDGCSNSEIAEHLFITVGTVKTHVRNILNKLCADDRTQA
AVRALRSGLVG

Sequences:

>Translated_251_residues
MYIDHAIFWKVSGKTMKKIRVVLIEDHDLTRIGLRTSLQQCADIELLAEAANGADGLRLLEEIHPDLAIVDIGLPELDGI
ELTRILKQEKLKDQSHEAQTKVLILTLQDDDAAVLAAFAAGADSYCMKDITFDHLVEAVKTTDSGNSWIDPAIARIVLNQ
VQGGEPLSGSTVTIQATSPEDQQLLESCPLTDRELEVLQLIVDGCSNSEIAEHLFITVGTVKTHVRNILNKLCADDRTQA
AVRALRSGLVG
>Mature_251_residues
MYIDHAIFWKVSGKTMKKIRVVLIEDHDLTRIGLRTSLQQCADIELLAEAANGADGLRLLEEIHPDLAIVDIGLPELDGI
ELTRILKQEKLKDQSHEAQTKVLILTLQDDDAAVLAAFAAGADSYCMKDITFDHLVEAVKTTDSGNSWIDPAIARIVLNQ
VQGGEPLSGSTVTIQATSPEDQQLLESCPLTDRELEVLQLIVDGCSNSEIAEHLFITVGTVKTHVRNILNKLCADDRTQA
AVRALRSGLVG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=224, Percent_Identity=29.9107142857143, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787473, Length=222, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788222, Length=232, Percent_Identity=26.2931034482759, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788712, Length=214, Percent_Identity=26.1682242990654, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790102, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786747, Length=218, Percent_Identity=26.1467889908257, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27399; Mature: 27399

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIDHAIFWKVSGKTMKKIRVVLIEDHDLTRIGLRTSLQQCADIELLAEAANGADGLRLL
CCCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EEIHPDLAIVDIGLPELDGIELTRILKQEKLKDQSHEAQTKVLILTLQDDDAAVLAAFAA
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHC
GADSYCMKDITFDHLVEAVKTTDSGNSWIDPAIARIVLNQVQGGEPLSGSTVTIQATSPE
CCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
DQQLLESCPLTDRELEVLQLIVDGCSNSEIAEHLFITVGTVKTHVRNILNKLCADDRTQA
HHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHEEHHHHHHHHHHHHHHHCCCCHHHH
AVRALRSGLVG
HHHHHHHCCCC
>Mature Secondary Structure
MYIDHAIFWKVSGKTMKKIRVVLIEDHDLTRIGLRTSLQQCADIELLAEAANGADGLRLL
CCCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EEIHPDLAIVDIGLPELDGIELTRILKQEKLKDQSHEAQTKVLILTLQDDDAAVLAAFAA
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHC
GADSYCMKDITFDHLVEAVKTTDSGNSWIDPAIARIVLNQVQGGEPLSGSTVTIQATSPE
CCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
DQQLLESCPLTDRELEVLQLIVDGCSNSEIAEHLFITVGTVKTHVRNILNKLCADDRTQA
HHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHEEHHHHHHHHHHHHHHHCCCCHHHH
AVRALRSGLVG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]