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The map label for this gene is ispD [H]

Identifier: 170078510

GI number: 170078510

Start: 1991349

End: 1992047

Strand: Direct

Name: ispD [H]

Synonym: SYNPCC7002_A1905

Alternate gene names: 170078510

Gene position: 1991349-1992047 (Clockwise)

Preceding gene: 170078504

Following gene: 170078514

Centisome position: 66.2

GC content: 53.65

Gene sequence:

>699_bases
ATGGTGCACTTGTTATTGCCTGCGGCGGGCGTCGGCAAACGGATGGGCGGCGATCGCAACAAACTGCTGATGACACTACA
GGATAAACCGCTCTTTAGTTGGACGCTCCAGGCAGCAGCGGCGGCGGATTCAGTGGCCTGGATTGGCATCATGGGACAGC
CCTTAGATTTTCCGGACTTTGAGGCAATTTTGGCCGATTTAAAGCTTTCTAAGCCTGTCCAACTGATTCGAGGTGGCAAA
ACTCGCCAAGAATCAGTTTATAACGGTCTACAAGCCCTTCCCCCAGAGGCAACCCAGGTGCTGATCCACGATGGGGCAAG
GTGTTTGGCCACCCCGGCGCTATTTAATCGCTGTGCAGCGGCCCTAGAAACCTGTGAGGGCTTAATTGCGGCGATTCCCG
TCAAGGACACCATTAAGGTAGTAGATGAACAAGGTTGGGTCAAAGAGACGCCGGAGCGGGCGAAGCTTTGGGCTGCCCAG
ACGCCCCAGGGGTTTACGGTGCAGCGCCTCAAGGATTGCCACGAAAAAGGCAAAACCCTGGGTTGGGAAGTGACCGATGA
TGCGGCTTTGTTCGAGCGTTGTGGTCTGCCTGTGAAAATTGTCTCTGGGGAAGAAACAAACCTCAAAATTACGACGCCAG
GAGATTTGGCGATCGCCGAATTTATTTTGCAGAGCCGTGATGAAATGCCAAAAACCTAG

Upstream 100 bases:

>100_bases
AACTAGGGCTAGTATGCGCATCTTGGGGGTATAAACTTACGTATCCAGCATCATTTTAGAAGAGAATAGGCGGAAACGTT
TAGTAACTTAGGGAAAAGCC

Downstream 100 bases:

>100_bases
GAGCTGGAAACCTCGGTGCTTTTTAACGGTAGCGGTTTGGGGTGGCGGTGCCGTTGGGTACGGTAAACCTGGATGGGGCG
GTCAATGCCTTTAAATCGCC

Product: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Products: NA

Alternate protein names: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MVHLLLPAAGVGKRMGGDRNKLLMTLQDKPLFSWTLQAAAAADSVAWIGIMGQPLDFPDFEAILADLKLSKPVQLIRGGK
TRQESVYNGLQALPPEATQVLIHDGARCLATPALFNRCAAALETCEGLIAAIPVKDTIKVVDEQGWVKETPERAKLWAAQ
TPQGFTVQRLKDCHEKGKTLGWEVTDDAALFERCGLPVKIVSGEETNLKITTPGDLAIAEFILQSRDEMPKT

Sequences:

>Translated_232_residues
MVHLLLPAAGVGKRMGGDRNKLLMTLQDKPLFSWTLQAAAAADSVAWIGIMGQPLDFPDFEAILADLKLSKPVQLIRGGK
TRQESVYNGLQALPPEATQVLIHDGARCLATPALFNRCAAALETCEGLIAAIPVKDTIKVVDEQGWVKETPERAKLWAAQ
TPQGFTVQRLKDCHEKGKTLGWEVTDDAALFERCGLPVKIVSGEETNLKITTPGDLAIAEFILQSRDEMPKT
>Mature_232_residues
MVHLLLPAAGVGKRMGGDRNKLLMTLQDKPLFSWTLQAAAAADSVAWIGIMGQPLDFPDFEAILADLKLSKPVQLIRGGK
TRQESVYNGLQALPPEATQVLIHDGARCLATPALFNRCAAALETCEGLIAAIPVKDTIKVVDEQGWVKETPERAKLWAAQ
TPQGFTVQRLKDCHEKGKTLGWEVTDDAALFERCGLPVKIVSGEETNLKITTPGDLAIAEFILQSRDEMPKT

Specific function: Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) [H]

COG id: COG1211

COG function: function code I; 4-diphosphocytidyl-2-methyl-D-erithritol synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispD family [H]

Homologues:

Organism=Homo sapiens, GI157412259, Length=239, Percent_Identity=27.1966527196653, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1789104, Length=223, Percent_Identity=34.5291479820628, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001228
- InterPro:   IPR018294 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.60 [H]

Molecular weight: Translated: 25241; Mature: 25241

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01295 ISPD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHLLLPAAGVGKRMGGDRNKLLMTLQDKPLFSWTLQAAAAADSVAWIGIMGQPLDFPDF
CEEEEECCCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCH
EAILADLKLSKPVQLIRGGKTRQESVYNGLQALPPEATQVLIHDGARCLATPALFNRCAA
HHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCHHHEEEEECCCHHHCCHHHHHHHHH
ALETCEGLIAAIPVKDTIKVVDEQGWVKETPERAKLWAAQTPQGFTVQRLKDCHEKGKTL
HHHHHHHHEEECCCHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCHHHHHHHHHHHCCCC
GWEVTDDAALFERCGLPVKIVSGEETNLKITTPGDLAIAEFILQSRDEMPKT
CCEECCHHHHHHHCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVHLLLPAAGVGKRMGGDRNKLLMTLQDKPLFSWTLQAAAAADSVAWIGIMGQPLDFPDF
CEEEEECCCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCH
EAILADLKLSKPVQLIRGGKTRQESVYNGLQALPPEATQVLIHDGARCLATPALFNRCAA
HHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCHHHEEEEECCCHHHCCHHHHHHHHH
ALETCEGLIAAIPVKDTIKVVDEQGWVKETPERAKLWAAQTPQGFTVQRLKDCHEKGKTL
HHHHHHHHEEECCCHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCHHHHHHHHHHHCCCC
GWEVTDDAALFERCGLPVKIVSGEETNLKITTPGDLAIAEFILQSRDEMPKT
CCEECCHHHHHHHCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA