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The map label for this gene is crtH [H]

Identifier: 170078497

GI number: 170078497

Start: 1976242

End: 1977783

Strand: Reverse

Name: crtH [H]

Synonym: SYNPCC7002_A1892

Alternate gene names: 170078497

Gene position: 1977783-1976242 (Counterclockwise)

Preceding gene: 170078498

Following gene: 170078494

Centisome position: 65.75

GC content: 50.71

Gene sequence:

>1542_bases
ATGACCGCCAAAACTGCCATTTCTGCTCCCCAGTACGATGTGATTGTCATTGGTTCCGGTATCGGGGGCCTCGTCACGGC
AACCCAATTAGCAGCGAAAGGGATCAAGGTGTTGGTGCTAGAACGCTATGTGATCCCCGGTGGCAGTGCGGGTTATTTTG
AGCGGCAGGGTTATCGGTTTGATGTGGGCGCTTCGATGATCTTTGGCTTTGGCGATCGCGGCACCACCAATCTCCTCACC
CGGGCCCTCGCCGCAGTGGATATGTCAATTGCGACCATCCCAGATCCGGTGCAAATTCATTACCATCTCCCCAATGATCT
TGAGGTCAAGGTACACCGTGACTACGAAGAATTTTTAACGGAGTTAACGGCACGGTTTCCCCACGAAGCCAAGGGCATTC
GTAAATTTTATGATGAGTGCTGGAAAGTTTTTAATTGCCTCAATAGTATTGAGCTGCTTTCCCTCGAAGAAATTCGCTAC
CTGCTGCGGGTCTTTATGCAGAAACCCTTTGCTTGCCTAGGGTTACTCAAATATTTACCCAAAAATGCTGGGGATCTCGC
CCGTCAATATATTAAAGACCCCGAACTGCTGAAGTTTATCGATATGGAATGTTACTGCTGGTCAGTGGTGCCAGCTGAAC
TGACTCCCATGATTAATGCGGGTATGGTGTTTAGCGATCGCCATTACGGGGGCATCAACTATCCAGAAGGCGGAGTGGGC
CAAATCGCCCTCAAACTGGTTGAAGGTTTCGAACAACATGGTGGTGAAATCCAATACGGTGCGAATGTCTACGAAATCAT
CACCGACCAAGGCCGGGCCGTCGGCGTGCGCTTAGCCAATGGCACCGAGTATTTCGCCAAAAAAGTCATTTCCAATGCCA
CCCGCTGGGACACTTTTGAAAAACTGCTCCCCAGTGAAAATAAACCCTTTTTTGAAGAAAAGTGGACGGAGAATTACCAA
AAATCCCCCAGCTTTCTCAGCGTTCACCTCGGTGTCAAAGCCGATGTTCTTCCTCCTGGGACGGAATGCCACCACATTTT
GCTGGAGAATTGGGACACCATGGAAGCCGAGCAAGGCACCATTTTTGTTTCTATTCCGACGCTCCTCGATCCGAGTCTGG
CCCCTGAGGGATACCACATCATTCACACCTTTACTCCCAGTTGGCTGAGTGAGTGGCAGGGCCTTTCTCCCCAGGAATAT
GAAGCCAAAAAAGAAGCCGCCGCCTGGCAACTCGTGGATCGCCTTGAAGCTATTTTTCCAGGGTTAGATGCGGGATTGGA
CTACATGGAAGTGGGGACACCGCGCACCCACCGCAAATTCCTCGGACGGGTCGATGGCTCCTACGGGCCGATTCCCCAAC
GCAAACTTTTGGGATTACTGGGAATGTTTAATTTTGCTGGTTTTCCACCCCGGGTCAATAAAACAGAAGTCTCTGGACTT
TATTGTGTCGGCGATAGTACCTTCCCCGGACAGGGCTTAAATGCTGTGGCGTTTTCTGGTTTTGCCTGCGCCCACAAAGT
AGCGACAGATCTCGGCTATTAA

Upstream 100 bases:

>100_bases
GCCGTAACATCGCCGGAGAGTTACCCTACTAATCCCAAGGGAAATAAAGGTAGACTATGTAACAGTCAAAATTTAGCCTA
TCTTGCGAGCCTCACCGTTT

Downstream 100 bases:

>100_bases
GTGACAGGCACAAGAAAGGCGATCGCCCTTGGGAAAAACAAAAAAGAGGGGTAAAATTCCCCTCCTGAGATCTTGTATTT
ACTTCACGTTGAAAACTGAC

Product: carotenoid cis-trans isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MTAKTAISAPQYDVIVIGSGIGGLVTATQLAAKGIKVLVLERYVIPGGSAGYFERQGYRFDVGASMIFGFGDRGTTNLLT
RALAAVDMSIATIPDPVQIHYHLPNDLEVKVHRDYEEFLTELTARFPHEAKGIRKFYDECWKVFNCLNSIELLSLEEIRY
LLRVFMQKPFACLGLLKYLPKNAGDLARQYIKDPELLKFIDMECYCWSVVPAELTPMINAGMVFSDRHYGGINYPEGGVG
QIALKLVEGFEQHGGEIQYGANVYEIITDQGRAVGVRLANGTEYFAKKVISNATRWDTFEKLLPSENKPFFEEKWTENYQ
KSPSFLSVHLGVKADVLPPGTECHHILLENWDTMEAEQGTIFVSIPTLLDPSLAPEGYHIIHTFTPSWLSEWQGLSPQEY
EAKKEAAAWQLVDRLEAIFPGLDAGLDYMEVGTPRTHRKFLGRVDGSYGPIPQRKLLGLLGMFNFAGFPPRVNKTEVSGL
YCVGDSTFPGQGLNAVAFSGFACAHKVATDLGY

Sequences:

>Translated_513_residues
MTAKTAISAPQYDVIVIGSGIGGLVTATQLAAKGIKVLVLERYVIPGGSAGYFERQGYRFDVGASMIFGFGDRGTTNLLT
RALAAVDMSIATIPDPVQIHYHLPNDLEVKVHRDYEEFLTELTARFPHEAKGIRKFYDECWKVFNCLNSIELLSLEEIRY
LLRVFMQKPFACLGLLKYLPKNAGDLARQYIKDPELLKFIDMECYCWSVVPAELTPMINAGMVFSDRHYGGINYPEGGVG
QIALKLVEGFEQHGGEIQYGANVYEIITDQGRAVGVRLANGTEYFAKKVISNATRWDTFEKLLPSENKPFFEEKWTENYQ
KSPSFLSVHLGVKADVLPPGTECHHILLENWDTMEAEQGTIFVSIPTLLDPSLAPEGYHIIHTFTPSWLSEWQGLSPQEY
EAKKEAAAWQLVDRLEAIFPGLDAGLDYMEVGTPRTHRKFLGRVDGSYGPIPQRKLLGLLGMFNFAGFPPRVNKTEVSGL
YCVGDSTFPGQGLNAVAFSGFACAHKVATDLGY
>Mature_512_residues
TAKTAISAPQYDVIVIGSGIGGLVTATQLAAKGIKVLVLERYVIPGGSAGYFERQGYRFDVGASMIFGFGDRGTTNLLTR
ALAAVDMSIATIPDPVQIHYHLPNDLEVKVHRDYEEFLTELTARFPHEAKGIRKFYDECWKVFNCLNSIELLSLEEIRYL
LRVFMQKPFACLGLLKYLPKNAGDLARQYIKDPELLKFIDMECYCWSVVPAELTPMINAGMVFSDRHYGGINYPEGGVGQ
IALKLVEGFEQHGGEIQYGANVYEIITDQGRAVGVRLANGTEYFAKKVISNATRWDTFEKLLPSENKPFFEEKWTENYQK
SPSFLSVHLGVKADVLPPGTECHHILLENWDTMEAEQGTIFVSIPTLLDPSLAPEGYHIIHTFTPSWLSEWQGLSPQEYE
AKKEAAAWQLVDRLEAIFPGLDAGLDYMEVGTPRTHRKFLGRVDGSYGPIPQRKLLGLLGMFNFAGFPPRVNKTEVSGLY
CVGDSTFPGQGLNAVAFSGFACAHKVATDLGY

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=490, Percent_Identity=24.6938775510204, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540238, Length=554, Percent_Identity=23.826714801444, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 57067; Mature: 56936

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTAISAPQYDVIVIGSGIGGLVTATQLAAKGIKVLVLERYVIPGGSAGYFERQGYRF
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEEE
DVGASMIFGFGDRGTTNLLTRALAAVDMSIATIPDPVQIHYHLPNDLEVKVHRDYEEFLT
ECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCHHHHHH
ELTARFPHEAKGIRKFYDECWKVFNCLNSIELLSLEEIRYLLRVFMQKPFACLGLLKYLP
HHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
KNAGDLARQYIKDPELLKFIDMECYCWSVVPAELTPMINAGMVFSDRHYGGINYPEGGVG
CCHHHHHHHHHCCCHHHHHHCCCEEEEEECCHHHCCHHCCCEEEECCCCCCCCCCCCCHH
QIALKLVEGFEQHGGEIQYGANVYEIITDQGRAVGVRLANGTEYFAKKVISNATRWDTFE
HHHHHHHHHHHHCCCEEEECCCEEEEECCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHH
KLLPSENKPFFEEKWTENYQKSPSFLSVHLGVKADVLPPGTECHHILLENWDTMEAEQGT
HHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCHHHHHHCCCCCCCCCCCE
IFVSIPTLLDPSLAPEGYHIIHTFTPSWLSEWQGLSPQEYEAKKEAAAWQLVDRLEAIFP
EEEEEHHHCCCCCCCCCEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GLDAGLDYMEVGTPRTHRKFLGRVDGSYGPIPQRKLLGLLGMFNFAGFPPRVNKTEVSGL
CHHCCCCHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCEE
YCVGDSTFPGQGLNAVAFSGFACAHKVATDLGY
EEECCCCCCCCCCCHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TAKTAISAPQYDVIVIGSGIGGLVTATQLAAKGIKVLVLERYVIPGGSAGYFERQGYRF
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEEE
DVGASMIFGFGDRGTTNLLTRALAAVDMSIATIPDPVQIHYHLPNDLEVKVHRDYEEFLT
ECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCHHHHHH
ELTARFPHEAKGIRKFYDECWKVFNCLNSIELLSLEEIRYLLRVFMQKPFACLGLLKYLP
HHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
KNAGDLARQYIKDPELLKFIDMECYCWSVVPAELTPMINAGMVFSDRHYGGINYPEGGVG
CCHHHHHHHHHCCCHHHHHHCCCEEEEEECCHHHCCHHCCCEEEECCCCCCCCCCCCCHH
QIALKLVEGFEQHGGEIQYGANVYEIITDQGRAVGVRLANGTEYFAKKVISNATRWDTFE
HHHHHHHHHHHHCCCEEEECCCEEEEECCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHH
KLLPSENKPFFEEKWTENYQKSPSFLSVHLGVKADVLPPGTECHHILLENWDTMEAEQGT
HHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCHHHHHHCCCCCCCCCCCE
IFVSIPTLLDPSLAPEGYHIIHTFTPSWLSEWQGLSPQEYEAKKEAAAWQLVDRLEAIFP
EEEEEHHHCCCCCCCCCEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GLDAGLDYMEVGTPRTHRKFLGRVDGSYGPIPQRKLLGLLGMFNFAGFPPRVNKTEVSGL
CHHCCCCHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCEE
YCVGDSTFPGQGLNAVAFSGFACAHKVATDLGY
EEECCCCCCCCCCCHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]