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The map label for this gene is crp [H]

Identifier: 170078467

GI number: 170078467

Start: 1951045

End: 1951725

Strand: Direct

Name: crp [H]

Synonym: SYNPCC7002_A1861

Alternate gene names: 170078467

Gene position: 1951045-1951725 (Clockwise)

Preceding gene: 170078464

Following gene: 170078468

Centisome position: 64.86

GC content: 49.93

Gene sequence:

>681_bases
ATGGACATTGAAGCTTTTAGCGAGCTTTTCCCCCTCTTTAGCACCGCAAACCCCGAAACCATCGAATGGCTCCTGTCTGT
CACCACCGAGCATGACTATCCCGCAGAACGCACCGTCTTAATGGAAGACTCCTGGGGCAATGCCGTCTATTTCATCGAAT
CCGGCTGGGTTAAGGTGCGCCGCCTCACAGAGGATGGTGAAACTGTGACCCTCGCAATTATGGGCAAAGGTGATTTTTTT
GGGGAAATGTCAGTACTAGATGAATCGCCCCGTTCCACGGATGTGGTGGCCCTTTCGCCGGTCAAACTATTCAGTGTTTC
GGCCCAACGTTTTATCCAGCTACTGTTTAAAGACCCCCAATTGCACCACAAAATGCTGCAACTCATGGTGCGTCGTCTTC
GTAATGCCAATGCCCGGTTTTCTTGGCGCAAGCAGCCCCCCGCCCTCAAGTTAGTCAAAACTCTCCTCCTCCTGGCAGAA
AACTACGGTCAACCCACGGAACAGGGCCTAGAAATTATTCAATTGTCGGTGTCTGACCTGGCCGATGTGGCTGATATCAG
CACGAAAGAAGTTGAGATGATTCTGTCTAAACTGGAAGGGAAAGGGTGGATCGAAATGGGTGAAGGTCGCATTCATTTGA
TCAACTTTAAACAACTGACAAATTTAGCCAACCGAGCATAG

Upstream 100 bases:

>100_bases
GTGAGCTATTCTGAAAAGAAAACGTGCGAAAATAGCGCCTAACAGCCAATCACCTTGTATTCGTTGTATTGTTTCATTCT
GCACATCCTGGCAAGATTTC

Downstream 100 bases:

>100_bases
GAGTAAATTTTTTCTGATGGTTCACACGGCAACTTCCATGGCAACGCCAGCCCCAAGCGCGCAAAATACGGTGGCGATCG
CCTATCAAGTGGCAATGCCC

Product: transcriptional regulator

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDIEAFSELFPLFSTANPETIEWLLSVTTEHDYPAERTVLMEDSWGNAVYFIESGWVKVRRLTEDGETVTLAIMGKGDFF
GEMSVLDESPRSTDVVALSPVKLFSVSAQRFIQLLFKDPQLHHKMLQLMVRRLRNANARFSWRKQPPALKLVKTLLLLAE
NYGQPTEQGLEIIQLSVSDLADVADISTKEVEMILSKLEGKGWIEMGEGRIHLINFKQLTNLANRA

Sequences:

>Translated_226_residues
MDIEAFSELFPLFSTANPETIEWLLSVTTEHDYPAERTVLMEDSWGNAVYFIESGWVKVRRLTEDGETVTLAIMGKGDFF
GEMSVLDESPRSTDVVALSPVKLFSVSAQRFIQLLFKDPQLHHKMLQLMVRRLRNANARFSWRKQPPALKLVKTLLLLAE
NYGQPTEQGLEIIQLSVSDLADVADISTKEVEMILSKLEGKGWIEMGEGRIHLINFKQLTNLANRA
>Mature_226_residues
MDIEAFSELFPLFSTANPETIEWLLSVTTEHDYPAERTVLMEDSWGNAVYFIESGWVKVRRLTEDGETVTLAIMGKGDFF
GEMSVLDESPRSTDVVALSPVKLFSVSAQRFIQLLFKDPQLHHKMLQLMVRRLRNANARFSWRKQPPALKLVKTLLLLAE
NYGQPTEQGLEIIQLSVSDLADVADISTKEVEMILSKLEGKGWIEMGEGRIHLINFKQLTNLANRA

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25654; Mature: 25654

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIEAFSELFPLFSTANPETIEWLLSVTTEHDYPAERTVLMEDSWGNAVYFIESGWVKVR
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCEEEE
RLTEDGETVTLAIMGKGDFFGEMSVLDESPRSTDVVALSPVKLFSVSAQRFIQLLFKDPQ
EECCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCH
LHHKMLQLMVRRLRNANARFSWRKQPPALKLVKTLLLLAENYGQPTEQGLEIIQLSVSDL
HHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHEEEHHHHHH
ADVADISTKEVEMILSKLEGKGWIEMGEGRIHLINFKQLTNLANRA
HHHHCCCHHHHHHHHHHHCCCCCEEECCCEEEEEEHHHHHHHHHCC
>Mature Secondary Structure
MDIEAFSELFPLFSTANPETIEWLLSVTTEHDYPAERTVLMEDSWGNAVYFIESGWVKVR
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCEEEE
RLTEDGETVTLAIMGKGDFFGEMSVLDESPRSTDVVALSPVKLFSVSAQRFIQLLFKDPQ
EECCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCH
LHHKMLQLMVRRLRNANARFSWRKQPPALKLVKTLLLLAENYGQPTEQGLEIIQLSVSDL
HHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHEEEHHHHHH
ADVADISTKEVEMILSKLEGKGWIEMGEGRIHLINFKQLTNLANRA
HHHHCCCHHHHHHHHHHHCCCCCEEECCCEEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]