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The map label for this gene is sufS [H]

Identifier: 170078417

GI number: 170078417

Start: 1898811

End: 1900073

Strand: Reverse

Name: sufS [H]

Synonym: SYNPCC7002_A1811

Alternate gene names: 170078417

Gene position: 1900073-1898811 (Counterclockwise)

Preceding gene: 170078418

Following gene: 170078414

Centisome position: 63.17

GC content: 51.94

Gene sequence:

>1263_bases
ATGATCACAACCCAACCGAAACCCCTTGCCGAACAGGTTCGTGACGACTTTCCCATCCTGCACCAAACCGTGCACGGAAA
GCCACTGATCTACTTCGATAACGCTGCCACCTCCCAAAAGCCCAAGGCCGTCCTCGATGCGTTGCTGCATTATTACCAGC
AAGATAATGCCAATGTTCACCGGGGGATCCATAGTCTTAGTGCCCGGGCAACGGATGGCTACGAAGGGGCACGGGATAAA
GTCGCCCGGTTTATCAATGCGGCCAGTCGTGATGAAATCGTCTACACCCGCAATGCCAGTGAAGCGATTAATCTTGTCGC
CTACAGTTGGGGGTTGAGTAATCTAGGGCCGGGGGATGAAATTATCCTGTCGGTAATGGAACACCACAGCAATATTGTGC
CTTGGCAAATGATCGCGGCGAAAACTGGCGCTGTCTTGAAGTATGTACCGTTAACCCAGGATGAAACCTTTGATTTTGAG
CAATACCAAGCGCTACTTAGCGACAAAACGAAACTAGTCACAGTGGTTCATGTCTCCAATACTTTGGGCAATGTCAATCC
GGTGACCGAGATCATTCAAGCGGCCCGTAAATATGGCGCGAAAATCCTTATCGATGCCTGCCAGAGTTTGCCCCATATGC
CCGTTGATGTGCAGCAAATGGACTGTGACTGGCTTGTCGGCTCTGGTCACAAAATGTGTGCACCCACAGGAATTGGTTTT
CTTTATGGAAAACGAGCAATTCTCGAAGCGATGCCCCCTTTCTTGGGCGGTGGAGAAATGATCGCCGAGGTCTTCTTTGA
TCATTCTACCTACGGTGAACTGCCCCATAAATTTGAAGCGGGAACCCCAGCCATCGGTGAGGCGATCGCCCTTGGAGCGG
CGGTGGATTATCTCTCTCAAATTGGGATGGATCGCATCCATGCCTACGAAGCCGAACTCACTGCCTATCTTTTTAAGGGA
CTCCGGGACATCCCGAACCTAAAAATTTATGGCAAACAACCCGATGCCCAGGGGGAAGGTCGGGCGGCCCTCGCGGCCTT
TAATGTTGCTGGTGTCCATGCCAATGACTTAGCGACCCTCCTCGACCACGAAGGGGTTGCGATTCGTTCGGGCCATCACT
GCACCCAACCCCTCCACCGTCTGTTTGAGGCCTCTGGCAGTGCCCGCGCCAGCCTCTATTTTTACAACACCACCGCTGAA
ATCGATCAGTTTATTGCTGCCCTGAAGGACACCATTGATTTCTTTACCAGCATGGGTAGTTAA

Upstream 100 bases:

>100_bases
GCAGGCCCTTACGGGTTGTGTTGCCTGTCGCACCGTTGACTAACTTGTAAATTGCCGCCCCAACTGTTCCCGCTTACCCA
TCCGACCCAGTGAATCCCCT

Downstream 100 bases:

>100_bases
TGAAGCATACTTCTCAAATCTCCCTAATTTTCGCTAACTGCTAGAGATCATCAGGCAATACTACGAAAACTCACATTGTC
TCCTTCTTCTGACTGTTTAA

Product: cysteine desulfurase SufS; FeS assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MITTQPKPLAEQVRDDFPILHQTVHGKPLIYFDNAATSQKPKAVLDALLHYYQQDNANVHRGIHSLSARATDGYEGARDK
VARFINAASRDEIVYTRNASEAINLVAYSWGLSNLGPGDEIILSVMEHHSNIVPWQMIAAKTGAVLKYVPLTQDETFDFE
QYQALLSDKTKLVTVVHVSNTLGNVNPVTEIIQAARKYGAKILIDACQSLPHMPVDVQQMDCDWLVGSGHKMCAPTGIGF
LYGKRAILEAMPPFLGGGEMIAEVFFDHSTYGELPHKFEAGTPAIGEAIALGAAVDYLSQIGMDRIHAYEAELTAYLFKG
LRDIPNLKIYGKQPDAQGEGRAALAAFNVAGVHANDLATLLDHEGVAIRSGHHCTQPLHRLFEASGSARASLYFYNTTAE
IDQFIAALKDTIDFFTSMGS

Sequences:

>Translated_420_residues
MITTQPKPLAEQVRDDFPILHQTVHGKPLIYFDNAATSQKPKAVLDALLHYYQQDNANVHRGIHSLSARATDGYEGARDK
VARFINAASRDEIVYTRNASEAINLVAYSWGLSNLGPGDEIILSVMEHHSNIVPWQMIAAKTGAVLKYVPLTQDETFDFE
QYQALLSDKTKLVTVVHVSNTLGNVNPVTEIIQAARKYGAKILIDACQSLPHMPVDVQQMDCDWLVGSGHKMCAPTGIGF
LYGKRAILEAMPPFLGGGEMIAEVFFDHSTYGELPHKFEAGTPAIGEAIALGAAVDYLSQIGMDRIHAYEAELTAYLFKG
LRDIPNLKIYGKQPDAQGEGRAALAAFNVAGVHANDLATLLDHEGVAIRSGHHCTQPLHRLFEASGSARASLYFYNTTAE
IDQFIAALKDTIDFFTSMGS
>Mature_420_residues
MITTQPKPLAEQVRDDFPILHQTVHGKPLIYFDNAATSQKPKAVLDALLHYYQQDNANVHRGIHSLSARATDGYEGARDK
VARFINAASRDEIVYTRNASEAINLVAYSWGLSNLGPGDEIILSVMEHHSNIVPWQMIAAKTGAVLKYVPLTQDETFDFE
QYQALLSDKTKLVTVVHVSNTLGNVNPVTEIIQAARKYGAKILIDACQSLPHMPVDVQQMDCDWLVGSGHKMCAPTGIGF
LYGKRAILEAMPPFLGGGEMIAEVFFDHSTYGELPHKFEAGTPAIGEAIALGAAVDYLSQIGMDRIHAYEAELTAYLFKG
LRDIPNLKIYGKQPDAQGEGRAALAAFNVAGVHANDLATLLDHEGVAIRSGHHCTQPLHRLFEASGSARASLYFYNTTAE
IDQFIAALKDTIDFFTSMGS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=353, Percent_Identity=26.3456090651558, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI156713448, Length=314, Percent_Identity=25.796178343949, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1787970, Length=400, Percent_Identity=47.5, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1789175, Length=405, Percent_Identity=38.0246913580247, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI48994898, Length=401, Percent_Identity=25.4364089775561, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=351, Percent_Identity=28.2051282051282, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI193211090, Length=379, Percent_Identity=24.802110817942, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=408, Percent_Identity=26.4705882352941, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI20129463, Length=369, Percent_Identity=27.3712737127371, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45943; Mature: 45943

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTQPKPLAEQVRDDFPILHQTVHGKPLIYFDNAATSQKPKAVLDALLHYYQQDNANVH
CCCCCCCHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHH
RGIHSLSARATDGYEGARDKVARFINAASRDEIVYTRNASEAINLVAYSWGLSNLGPGDE
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHEEECCCCCCCCHHH
IILSVMEHHSNIVPWQMIAAKTGAVLKYVPLTQDETFDFEQYQALLSDKTKLVTVVHVSN
HHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEEECC
TLGNVNPVTEIIQAARKYGAKILIDACQSLPHMPVDVQQMDCDWLVGSGHKMCAPTGIGF
CCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHCCCCEEECCCCCEECCCCCHH
LYGKRAILEAMPPFLGGGEMIAEVFFDHSTYGELPHKFEAGTPAIGEAIALGAAVDYLSQ
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
IGMDRIHAYEAELTAYLFKGLRDIPNLKIYGKQPDAQGEGRAALAAFNVAGVHANDLATL
HCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHH
LDHEGVAIRSGHHCTQPLHRLFEASGSARASLYFYNTTAEIDQFIAALKDTIDFFTSMGS
HCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITTQPKPLAEQVRDDFPILHQTVHGKPLIYFDNAATSQKPKAVLDALLHYYQQDNANVH
CCCCCCCHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHH
RGIHSLSARATDGYEGARDKVARFINAASRDEIVYTRNASEAINLVAYSWGLSNLGPGDE
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHEEECCCCCCCCHHH
IILSVMEHHSNIVPWQMIAAKTGAVLKYVPLTQDETFDFEQYQALLSDKTKLVTVVHVSN
HHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEEECC
TLGNVNPVTEIIQAARKYGAKILIDACQSLPHMPVDVQQMDCDWLVGSGHKMCAPTGIGF
CCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHCCCCEEECCCCCEECCCCCHH
LYGKRAILEAMPPFLGGGEMIAEVFFDHSTYGELPHKFEAGTPAIGEAIALGAAVDYLSQ
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
IGMDRIHAYEAELTAYLFKGLRDIPNLKIYGKQPDAQGEGRAALAAFNVAGVHANDLATL
HCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHH
LDHEGVAIRSGHHCTQPLHRLFEASGSARASLYFYNTTAEIDQFIAALKDTIDFFTSMGS
HCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]