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The map label for this gene is ndhF4 [H]

Identifier: 170078411

GI number: 170078411

Start: 1891086

End: 1892984

Strand: Direct

Name: ndhF4 [H]

Synonym: SYNPCC7002_A1805

Alternate gene names: 170078411

Gene position: 1891086-1892984 (Clockwise)

Preceding gene: 170078398

Following gene: 170078412

Centisome position: 62.87

GC content: 51.13

Gene sequence:

>1899_bases
ATGAGTGAATTTCTTTTACAAAGCGTATGGCTAGTTCCAGTCTACGGAATTACGGGGGCACTCTTGACCTTGCCTTGGTC
CCTCGGGTTAATTCGGCGCACCGGGCCTCGACCTGCCGCCTATCTCAACCTGATCATGACCTTTTTGGGTCTTTTACACG
GTTCCTTTGCCTTCGCTTCCCTTTGGAACATGCCCCCCCAACAACTATCACTGGAGTGGCTCCAGGTTGCCGATCTAAAT
CTTTCCCTGGTTATTGAAATTTCTCCGGTTAACCTCGGCGCAATGGAACTGGTGACTGGCATTTGTTTCATGGCCCAACT
CTACGGCCTTGGGTACCTAGAAAAGGATTGGTCTATTGCCCGCTTCTATGGCTTGATGGGCTTTTTTGAGGCGGCCCTAT
CGGGTTTGGCCATTAGCGACTCGCTGCTCTTGAGCTATGGCCTGTTGGAAGTATTAACCCTTTCTACTTATTTATTAGTT
GGTTTTTGGTACGCCCAACCCCTGGTCGTGACAGCGGCTAGGGATGCTTTTTTGACCAAACGGGTCGGCGATATCTTGCT
CTTGATGGGCATTGTTGCTTTGTCTAGCTATGGTACGGGGCTCACTTTTAGTGAACTAGAAACTTGGGCGGCGAATCCCC
CCTTGCCCCCCTGGGAAGCCAGTCTCGTGGGCCTTGCGCTCATTTCCGGGCCGATTGGTAAATGTGCCCAGTTCCCGTTG
AACCTCTGGCTTGATGAAGCGATGGAAGGGCCAAACCCAGCGGGGATTATTCGTAATTCGGTGGTGGTTTCTGCGGGGGC
CTATGTACTGCTCAAAATGGAGCCCGTTTTTACGATTACGCCGATCACCTCCGACGCTTTGATTATTATCGGTACCGTAA
CTACGGTGGGGGCTTCGTTGGTTGCCCTAGCTCAAATTGATATTAAGCGGGCCTTATCCCATTCCACCAGTGCTTACCTT
GGTTTGGTGTTTATTGCGGTGGGGTTAAATCAAGTCGATATTGCCCTGTTGCTTTTGCTAACCCATGCGATCGCCAAAGC
GCTCTTATTTATGAGTATTGGTGCGGTTATTCTCAATACCCACGGTCAAAATATTACGGAAATGGGTGGCCTCTGGTCAC
GGATGCCGGCAACCACTAGTGCCTTTGTGGTGGGGTCAGCGGGGCTTGTGTGCCTCTTTCCCCTGGGGACGTTTTGGACG
ATGCGCCGTTGGGTCGATGGTTTTTGGGATACACCCCCGTGGCTCGTGCTGCTCCTCGTGGGAGTAAACTTCTGCTCCAG
TTTTAATCTGACCAGGGTCTTTCGTTCTGTTTTCCTCGGTGCCCCCAAGCCAAAAACGCGGCGATCGCCTGAGGTGGTCT
GGCAAATGGCTGTGCCCATGGTGAGTCTGATCCTAATGACCCTGATGGTGCCCTTCTTTTTGCACCAATGGCAATTGCTC
TTTAACCCATCCCTGCCGACCCTTGTTGAACGGCCGCTCATCGTGACTTTAGCAATACCAGCACTGATGATCACTGGGGG
CCTCGGCTTAGTCGCTGGTCTAACGATTACTTTGAATCCTTCCCTGAGTCGTCCCCGACAGCTTTATCTGCGCTTTTTGC
AGGATTTGCTGGCCTACGATTTTTACATTGACCGCATTTACAACGTGACAGTGGTTTGGCTGGTCACAACCCTTTCAAAA
CTCGCCGCTTGGTTTGATCGCTACGTTGTGGATGGTTTTGTCAACTTGACAGGTTTGGCGACACTTTTTAGTGGAAGCGC
CCTGCGTTACAACGTTTCGGGACAGTCTCAATTCTATGTTTTGACGATTGTTTTAGGGATGATCCTCGGCCTAGTCTGGT
TTATGGCCACGGGTCAATGGACGATGATTACGGATTTTTGGTCGAATCAGTTGGCCTAA

Upstream 100 bases:

>100_bases
CACTCTCTTACAAAGACTGTAGACCGACGATTTGAAATATTTTCTGGCCAATCCACCCAATGCCAACCAACCTTCTGTTG
TGATTTTCTAGACACCCTCC

Downstream 100 bases:

>100_bases
GGAGTTTCCCCCTTTGTTGTTAAATCTGCTTTTTTGTGAATTTTGGAGGAAAGAATGCTGAGTGCCTTAATTTGGCTGCC
CTTGGCCGGAGCTCTGTTGG

Product: NAD(P)H-quinone oxidoreductase subunit F

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I, chain 5; NDH-1, chain 5 [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MSEFLLQSVWLVPVYGITGALLTLPWSLGLIRRTGPRPAAYLNLIMTFLGLLHGSFAFASLWNMPPQQLSLEWLQVADLN
LSLVIEISPVNLGAMELVTGICFMAQLYGLGYLEKDWSIARFYGLMGFFEAALSGLAISDSLLLSYGLLEVLTLSTYLLV
GFWYAQPLVVTAARDAFLTKRVGDILLLMGIVALSSYGTGLTFSELETWAANPPLPPWEASLVGLALISGPIGKCAQFPL
NLWLDEAMEGPNPAGIIRNSVVVSAGAYVLLKMEPVFTITPITSDALIIIGTVTTVGASLVALAQIDIKRALSHSTSAYL
GLVFIAVGLNQVDIALLLLLTHAIAKALLFMSIGAVILNTHGQNITEMGGLWSRMPATTSAFVVGSAGLVCLFPLGTFWT
MRRWVDGFWDTPPWLVLLLVGVNFCSSFNLTRVFRSVFLGAPKPKTRRSPEVVWQMAVPMVSLILMTLMVPFFLHQWQLL
FNPSLPTLVERPLIVTLAIPALMITGGLGLVAGLTITLNPSLSRPRQLYLRFLQDLLAYDFYIDRIYNVTVVWLVTTLSK
LAAWFDRYVVDGFVNLTGLATLFSGSALRYNVSGQSQFYVLTIVLGMILGLVWFMATGQWTMITDFWSNQLA

Sequences:

>Translated_632_residues
MSEFLLQSVWLVPVYGITGALLTLPWSLGLIRRTGPRPAAYLNLIMTFLGLLHGSFAFASLWNMPPQQLSLEWLQVADLN
LSLVIEISPVNLGAMELVTGICFMAQLYGLGYLEKDWSIARFYGLMGFFEAALSGLAISDSLLLSYGLLEVLTLSTYLLV
GFWYAQPLVVTAARDAFLTKRVGDILLLMGIVALSSYGTGLTFSELETWAANPPLPPWEASLVGLALISGPIGKCAQFPL
NLWLDEAMEGPNPAGIIRNSVVVSAGAYVLLKMEPVFTITPITSDALIIIGTVTTVGASLVALAQIDIKRALSHSTSAYL
GLVFIAVGLNQVDIALLLLLTHAIAKALLFMSIGAVILNTHGQNITEMGGLWSRMPATTSAFVVGSAGLVCLFPLGTFWT
MRRWVDGFWDTPPWLVLLLVGVNFCSSFNLTRVFRSVFLGAPKPKTRRSPEVVWQMAVPMVSLILMTLMVPFFLHQWQLL
FNPSLPTLVERPLIVTLAIPALMITGGLGLVAGLTITLNPSLSRPRQLYLRFLQDLLAYDFYIDRIYNVTVVWLVTTLSK
LAAWFDRYVVDGFVNLTGLATLFSGSALRYNVSGQSQFYVLTIVLGMILGLVWFMATGQWTMITDFWSNQLA
>Mature_631_residues
SEFLLQSVWLVPVYGITGALLTLPWSLGLIRRTGPRPAAYLNLIMTFLGLLHGSFAFASLWNMPPQQLSLEWLQVADLNL
SLVIEISPVNLGAMELVTGICFMAQLYGLGYLEKDWSIARFYGLMGFFEAALSGLAISDSLLLSYGLLEVLTLSTYLLVG
FWYAQPLVVTAARDAFLTKRVGDILLLMGIVALSSYGTGLTFSELETWAANPPLPPWEASLVGLALISGPIGKCAQFPLN
LWLDEAMEGPNPAGIIRNSVVVSAGAYVLLKMEPVFTITPITSDALIIIGTVTTVGASLVALAQIDIKRALSHSTSAYLG
LVFIAVGLNQVDIALLLLLTHAIAKALLFMSIGAVILNTHGQNITEMGGLWSRMPATTSAFVVGSAGLVCLFPLGTFWTM
RRWVDGFWDTPPWLVLLLVGVNFCSSFNLTRVFRSVFLGAPKPKTRRSPEVVWQMAVPMVSLILMTLMVPFFLHQWQLLF
NPSLPTLVERPLIVTLAIPALMITGGLGLVAGLTITLNPSLSRPRQLYLRFLQDLLAYDFYIDRIYNVTVVWLVTTLSKL
AAWFDRYVVDGFVNLTGLATLFSGSALRYNVSGQSQFYVLTIVLGMILGLVWFMATGQWTMITDFWSNQLA

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=341, Percent_Identity=30.4985337243402, Blast_Score=149, Evalue=7e-36,
Organism=Escherichia coli, GI1788614, Length=556, Percent_Identity=29.3165467625899, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1788827, Length=315, Percent_Identity=29.2063492063492, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788831, Length=399, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788829, Length=398, Percent_Identity=23.8693467336683, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788613, Length=366, Percent_Identity=23.4972677595628, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: 1.6.5.3

Molecular weight: Translated: 69257; Mature: 69126

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLLQSVWLVPVYGITGALLTLPWSLGLIRRTGPRPAAYLNLIMTFLGLLHGSFAFAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LWNMPPQQLSLEWLQVADLNLSLVIEISPVNLGAMELVTGICFMAQLYGLGYLEKDWSIA
HHCCCHHHHHHHHHHEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
RFYGLMGFFEAALSGLAISDSLLLSYGLLEVLTLSTYLLVGFWYAQPLVVTAARDAFLTK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHH
RVGDILLLMGIVALSSYGTGLTFSELETWAANPPLPPWEASLVGLALISGPIGKCAQFPL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCH
NLWLDEAMEGPNPAGIIRNSVVVSAGAYVLLKMEPVFTITPITSDALIIIGTVTTVGASL
HHHHHHHCCCCCCHHHHHCCEEEECCCEEEEEECCEEEEECCCCCCEEEEEEHHHHHHHH
VALAQIDIKRALSHSTSAYLGLVFIAVGLNQVDIALLLLLTHAIAKALLFMSIGAVILNT
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
HGQNITEMGGLWSRMPATTSAFVVGSAGLVCLFPLGTFWTMRRWVDGFWDTPPWLVLLLV
CCCCHHHHCCHHHCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHH
GVNFCSSFNLTRVFRSVFLGAPKPKTRRSPEVVWQMAVPMVSLILMTLMVPFFLHQWQLL
HHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FNPSLPTLVERPLIVTLAIPALMITGGLGLVAGLTITLNPSLSRPRQLYLRFLQDLLAYD
ECCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHH
FYIDRIYNVTVVWLVTTLSKLAAWFDRYVVDGFVNLTGLATLFSGSALRYNVSGQSQFYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
LTIVLGMILGLVWFMATGQWTMITDFWSNQLA
HHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCC
>Mature Secondary Structure 
SEFLLQSVWLVPVYGITGALLTLPWSLGLIRRTGPRPAAYLNLIMTFLGLLHGSFAFAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LWNMPPQQLSLEWLQVADLNLSLVIEISPVNLGAMELVTGICFMAQLYGLGYLEKDWSIA
HHCCCHHHHHHHHHHEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
RFYGLMGFFEAALSGLAISDSLLLSYGLLEVLTLSTYLLVGFWYAQPLVVTAARDAFLTK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHH
RVGDILLLMGIVALSSYGTGLTFSELETWAANPPLPPWEASLVGLALISGPIGKCAQFPL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCH
NLWLDEAMEGPNPAGIIRNSVVVSAGAYVLLKMEPVFTITPITSDALIIIGTVTTVGASL
HHHHHHHCCCCCCHHHHHCCEEEECCCEEEEEECCEEEEECCCCCCEEEEEEHHHHHHHH
VALAQIDIKRALSHSTSAYLGLVFIAVGLNQVDIALLLLLTHAIAKALLFMSIGAVILNT
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
HGQNITEMGGLWSRMPATTSAFVVGSAGLVCLFPLGTFWTMRRWVDGFWDTPPWLVLLLV
CCCCHHHHCCHHHCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHH
GVNFCSSFNLTRVFRSVFLGAPKPKTRRSPEVVWQMAVPMVSLILMTLMVPFFLHQWQLL
HHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FNPSLPTLVERPLIVTLAIPALMITGGLGLVAGLTITLNPSLSRPRQLYLRFLQDLLAYD
ECCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHH
FYIDRIYNVTVVWLVTTLSKLAAWFDRYVVDGFVNLTGLATLFSGSALRYNVSGQSQFYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
LTIVLGMILGLVWFMATGQWTMITDFWSNQLA
HHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]