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The map label for this gene is resE [H]

Identifier: 170077977

GI number: 170077977

Start: 1423807

End: 1425120

Strand: Reverse

Name: resE [H]

Synonym: SYNPCC7002_A1363

Alternate gene names: 170077977

Gene position: 1425120-1423807 (Counterclockwise)

Preceding gene: 170077978

Following gene: 170077975

Centisome position: 47.38

GC content: 50.53

Gene sequence:

>1314_bases
ATGTTTCAAACCACCCGTAATCGTCTGGCCCTCTGGTACACGGCGATCACCGCAGTGTTGCTTTTGGTTTTCGCGACGGG
GGTTTATTTTTACGTGCGCTACACCCTGATTGAACGCATCGATGACACCCTAAAGCACGTAGTGGAAGTGGTAGAGCGAT
CGCTGATCATTGAGCCAGATGATCCTGTGGGCTATCACATCAATTTAGAAGCCAGCTTTCGGCAACAGTCCCCCACCGTC
GAAGATGACCGCATTGACCTCGAATTTTTCAACCCAGCCGGAGAATTGCTCTGGTCTACTTTTTCTGAACCATTAGTCTT
GCCCCTAGAGTGGCACCCCCGGGGGGAAACGGTACGTCTGGGTGATGATTATCTTCTGCGACAAATCACCGATCGCCTCG
AAGTGGATCGCTATGTTTTGGGGTATCTACGGGTGAGCCATCCTTGGTTTGAGGTGACGCGACCAATTCGCAAATTAGTC
CTTGATCTCAGCCTGGGGATCGCGATCATGATTACCTGTGGGGCGGTGATTGGCTGGTTACTGTCTGGTATTGCCATCGA
ACCGGTAAAGGATTCCTATCAACAATTGCGGCAATTTACGGCGGATGCGTCCCACGAGTTGCGTAATCCCATTGCGATGA
TCCAAACCAATGTCCAAATGGCGATCACCTACCCAGATCCCGACCAACGCCAACAAAATCTCAAGGTGATTGAGCGACTC
ACCCAACGGTTGGGCCGTTTAGTGAATGATCTCTTATTTCTCGCCCGCAGTGATAGTGGGGTGCTTCAGGCGGAATTTGA
ACAATTACCCCTGGATGCTCTATTGCTGGAGGTTATTGAAGAACAACGGGCCATCTGCCGCCAGGAAAAAATTGAGTTGC
AGTTGGATATTCAAGGGGATGCCACCGAAGAAGCCTATCTCATCTTGGGAGACTGGGATCAGATGGCGCGCCTCTTTACA
AATCTGATCGGCAATGCGATCGCCTATGCTTTTCCAGGGGACTGGGGCGACAAACCCAAGCAAATTACCGTCACCATGGC
CCTCAAGGAGAAAACAGGGCGGACAACCGGAGAAACCCTCCAAGTGACGGTTAAAGATAATGGCATCGGTATTCCTGCCG
AAAATTCAACCAATATTTTCGACCGTTTTTATCGTCTTGATCCCGCCCGGACAAACCCTGGGGAAAGTAGCACTGGTTCA
GGTCTTGGCCTCGCCATTGCGGCGGCGATCGCCAAAAACCATAAAGGCAAAATCACCGTTGAAAGCAAAGATCAAGGCAC
AACATTTTCCGTTTTTTTACCACGAGCGACTTAA

Upstream 100 bases:

>100_bases
ATTACGCCTACCAAGAACCCGCTTCCCCCCAGGTTGAGGCTTTCCTTGGTTTTGTTGGGACTCCTGTGGGAGCAGAGTTG
ATCCAAGCGGCGCAGCAGTA

Downstream 100 bases:

>100_bases
GAGCTTATTTATAAAGCCCTCCTACCCTCAGTCTGGGGGAGATTTTCGGACAATCAATTGGGATCATTGGGATCAAAGTC
CTCCAAAATGAAAGTCTCTA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFQTTRNRLALWYTAITAVLLLVFATGVYFYVRYTLIERIDDTLKHVVEVVERSLIIEPDDPVGYHINLEASFRQQSPTV
EDDRIDLEFFNPAGELLWSTFSEPLVLPLEWHPRGETVRLGDDYLLRQITDRLEVDRYVLGYLRVSHPWFEVTRPIRKLV
LDLSLGIAIMITCGAVIGWLLSGIAIEPVKDSYQQLRQFTADASHELRNPIAMIQTNVQMAITYPDPDQRQQNLKVIERL
TQRLGRLVNDLLFLARSDSGVLQAEFEQLPLDALLLEVIEEQRAICRQEKIELQLDIQGDATEEAYLILGDWDQMARLFT
NLIGNAIAYAFPGDWGDKPKQITVTMALKEKTGRTTGETLQVTVKDNGIGIPAENSTNIFDRFYRLDPARTNPGESSTGS
GLGLAIAAAIAKNHKGKITVESKDQGTTFSVFLPRAT

Sequences:

>Translated_437_residues
MFQTTRNRLALWYTAITAVLLLVFATGVYFYVRYTLIERIDDTLKHVVEVVERSLIIEPDDPVGYHINLEASFRQQSPTV
EDDRIDLEFFNPAGELLWSTFSEPLVLPLEWHPRGETVRLGDDYLLRQITDRLEVDRYVLGYLRVSHPWFEVTRPIRKLV
LDLSLGIAIMITCGAVIGWLLSGIAIEPVKDSYQQLRQFTADASHELRNPIAMIQTNVQMAITYPDPDQRQQNLKVIERL
TQRLGRLVNDLLFLARSDSGVLQAEFEQLPLDALLLEVIEEQRAICRQEKIELQLDIQGDATEEAYLILGDWDQMARLFT
NLIGNAIAYAFPGDWGDKPKQITVTMALKEKTGRTTGETLQVTVKDNGIGIPAENSTNIFDRFYRLDPARTNPGESSTGS
GLGLAIAAAIAKNHKGKITVESKDQGTTFSVFLPRAT
>Mature_437_residues
MFQTTRNRLALWYTAITAVLLLVFATGVYFYVRYTLIERIDDTLKHVVEVVERSLIIEPDDPVGYHINLEASFRQQSPTV
EDDRIDLEFFNPAGELLWSTFSEPLVLPLEWHPRGETVRLGDDYLLRQITDRLEVDRYVLGYLRVSHPWFEVTRPIRKLV
LDLSLGIAIMITCGAVIGWLLSGIAIEPVKDSYQQLRQFTADASHELRNPIAMIQTNVQMAITYPDPDQRQQNLKVIERL
TQRLGRLVNDLLFLARSDSGVLQAEFEQLPLDALLLEVIEEQRAICRQEKIELQLDIQGDATEEAYLILGDWDQMARLFT
NLIGNAIAYAFPGDWGDKPKQITVTMALKEKTGRTTGETLQVTVKDNGIGIPAENSTNIFDRFYRLDPARTNPGESSTGS
GLGLAIAAAIAKNHKGKITVESKDQGTTFSVFLPRAT

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=32.2709163346614, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789403, Length=253, Percent_Identity=29.2490118577075, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=267, Percent_Identity=27.7153558052434, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=25.9414225941423, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=299, Percent_Identity=23.4113712374582, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=257, Percent_Identity=27.2373540856031, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=253, Percent_Identity=25.6916996047431, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=23.6947791164659, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=27.3722627737226, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=26.7206477732794, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49378; Mature: 49378

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTTRNRLALWYTAITAVLLLVFATGVYFYVRYTLIERIDDTLKHVVEVVERSLIIEPD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
DPVGYHINLEASFRQQSPTVEDDRIDLEFFNPAGELLWSTFSEPLVLPLEWHPRGETVRL
CCCCEEEEEEEHHCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCEEEE
GDDYLLRQITDRLEVDRYVLGYLRVSHPWFEVTRPIRKLVLDLSLGIAIMITCGAVIGWL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGIAIEPVKDSYQQLRQFTADASHELRNPIAMIQTNVQMAITYPDPDQRQQNLKVIERL
HHCCEECCHHHHHHHHHHHHCCHHHHHHCCCEEEECCEEEEEECCCCCHHHHHHHHHHHH
TQRLGRLVNDLLFLARSDSGVLQAEFEQLPLDALLLEVIEEQRAICRQEKIELQLDIQGD
HHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
ATEEAYLILGDWDQMARLFTNLIGNAIAYAFPGDWGDKPKQITVTMALKEKTGRTTGETL
CCCCEEEEEECHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCEE
QVTVKDNGIGIPAENSTNIFDRFYRLDPARTNPGESSTGSGLGLAIAAAIAKNHKGKITV
EEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
ESKDQGTTFSVFLPRAT
ECCCCCCEEEEEECCCC
>Mature Secondary Structure
MFQTTRNRLALWYTAITAVLLLVFATGVYFYVRYTLIERIDDTLKHVVEVVERSLIIEPD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
DPVGYHINLEASFRQQSPTVEDDRIDLEFFNPAGELLWSTFSEPLVLPLEWHPRGETVRL
CCCCEEEEEEEHHCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCEEEE
GDDYLLRQITDRLEVDRYVLGYLRVSHPWFEVTRPIRKLVLDLSLGIAIMITCGAVIGWL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGIAIEPVKDSYQQLRQFTADASHELRNPIAMIQTNVQMAITYPDPDQRQQNLKVIERL
HHCCEECCHHHHHHHHHHHHCCHHHHHHCCCEEEECCEEEEEECCCCCHHHHHHHHHHHH
TQRLGRLVNDLLFLARSDSGVLQAEFEQLPLDALLLEVIEEQRAICRQEKIELQLDIQGD
HHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
ATEEAYLILGDWDQMARLFTNLIGNAIAYAFPGDWGDKPKQITVTMALKEKTGRTTGETL
CCCCEEEEEECHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCEE
QVTVKDNGIGIPAENSTNIFDRFYRLDPARTNPGESSTGSGLGLAIAAAIAKNHKGKITV
EEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
ESKDQGTTFSVFLPRAT
ECCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]