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The map label for this gene is moaA

Identifier: 170077975

GI number: 170077975

Start: 1420695

End: 1421684

Strand: Reverse

Name: moaA

Synonym: SYNPCC7002_A1361

Alternate gene names: 170077975

Gene position: 1421684-1420695 (Counterclockwise)

Preceding gene: 170077977

Following gene: 170077974

Centisome position: 47.26

GC content: 50.61

Gene sequence:

>990_bases
ATGAATCCGGTAGATTATCTCCGCATTAGCTTGATTGATCGATGTAATTTTCGTTGCCATTACTGCGTCCCAGATGAAGC
GAGCCTCCAATATTTGCTGACCTCAGAGCAGTTGAGCAATGGGGAAATTCTCACGCTCCTCGAACAGGTGTTTATTCCCT
TGGGATTTCGTAAATTTCGCCTCACGGGGGGAGAGCCTCTCCTACGTCCCCAGTTAGTCCCCCTCGTCCGGGCGATCGCC
CACTTGCCGGGGGTAGAGGATTTATCGATGACCACAAATGCTTATTTACTAGCGGATCTGGCTCAGGATCTCTACAATGC
GGGTCTGAATCGTCTCAATATCAGCCTAGACTCTTTGAATCCTGAGACCTTTGATCAAATTATTGGCAATCGGGGCAAGA
GTCGCTGGCAGCAAACTTGGGAGGGCATCCAAGCGGCCCATCGGGTTGGTTTTGACCCCCTCAAGCTCAATGTCGTGGTG
ATCCCTGGGGTAAATGATCAAGAGGTATTAGATTTAGCCGCGTTGACAGGCGATCGCCATTGGCACGTGCGCTTTATTGA
GTTTATGCCCATCGGCAACGACAAATTATTTAATGAACGGGCCTGGATTCCTTCGGAAGAATTACGCCAACGGATCCGGG
CAAAATGGGGCTTAGAAACGGCATTCGTTCAGGGCAATGGCCCCGCAGATATTTTTAAGATTCCCGGGGCAAAGGGGACG
CTTGGGTTTATTTCCCAGATGTCTGAATGTTTTTGCGATCGCTGTAACCGGATGCGCCTCTCAGCGGATGGTTGGCTGCG
GCCTTGCCTATTGAATGAAGCAGCACAAATGGATCTCAAAACATTACTCCGGACTGGGGTTCCCCCTAGGGAAATTCGGG
CGGCAGTCAAAGCACTCCTCGACCAAAAACCAGAGATTAATTTCAAAATGCGCGATATGGGAACCACCACGGGTCAATAT
GGCCGCACCATGTCGCAAATTGGCGGCTAA

Upstream 100 bases:

>100_bases
TCGATATTTTTTTAAAGTCTGATCTGAACCAGACAGAGGATCGTCATCTTCTGTATCCTCAAAGGGAGCTTGTCCTTTAT
TTGTCGTGGTAGCAGTAAGC

Downstream 100 bases:

>100_bases
AGGGCAGTATTGTCTCGGATTCATTACATTTCGCGGCACAAAACGTCAATAAACGTGAATTAGGTTCCCCAAAGGGAGCT
TTTTTTTTCTAGAATATTTG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNPVDYLRISLIDRCNFRCHYCVPDEASLQYLLTSEQLSNGEILTLLEQVFIPLGFRKFRLTGGEPLLRPQLVPLVRAIA
HLPGVEDLSMTTNAYLLADLAQDLYNAGLNRLNISLDSLNPETFDQIIGNRGKSRWQQTWEGIQAAHRVGFDPLKLNVVV
IPGVNDQEVLDLAALTGDRHWHVRFIEFMPIGNDKLFNERAWIPSEELRQRIRAKWGLETAFVQGNGPADIFKIPGAKGT
LGFISQMSECFCDRCNRMRLSADGWLRPCLLNEAAQMDLKTLLRTGVPPREIRAAVKALLDQKPEINFKMRDMGTTTGQY
GRTMSQIGG

Sequences:

>Translated_329_residues
MNPVDYLRISLIDRCNFRCHYCVPDEASLQYLLTSEQLSNGEILTLLEQVFIPLGFRKFRLTGGEPLLRPQLVPLVRAIA
HLPGVEDLSMTTNAYLLADLAQDLYNAGLNRLNISLDSLNPETFDQIIGNRGKSRWQQTWEGIQAAHRVGFDPLKLNVVV
IPGVNDQEVLDLAALTGDRHWHVRFIEFMPIGNDKLFNERAWIPSEELRQRIRAKWGLETAFVQGNGPADIFKIPGAKGT
LGFISQMSECFCDRCNRMRLSADGWLRPCLLNEAAQMDLKTLLRTGVPPREIRAAVKALLDQKPEINFKMRDMGTTTGQY
GRTMSQIGG
>Mature_329_residues
MNPVDYLRISLIDRCNFRCHYCVPDEASLQYLLTSEQLSNGEILTLLEQVFIPLGFRKFRLTGGEPLLRPQLVPLVRAIA
HLPGVEDLSMTTNAYLLADLAQDLYNAGLNRLNISLDSLNPETFDQIIGNRGKSRWQQTWEGIQAAHRVGFDPLKLNVVV
IPGVNDQEVLDLAALTGDRHWHVRFIEFMPIGNDKLFNERAWIPSEELRQRIRAKWGLETAFVQGNGPADIFKIPGAKGT
LGFISQMSECFCDRCNRMRLSADGWLRPCLLNEAAQMDLKTLLRTGVPPREIRAAVKALLDQKPEINFKMRDMGTTTGQY
GRTMSQIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family

Homologues:

Organism=Homo sapiens, GI116734668, Length=326, Percent_Identity=38.9570552147239, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI22027536, Length=326, Percent_Identity=38.9570552147239, Blast_Score=217, Evalue=1e-56,
Organism=Escherichia coli, GI1786999, Length=324, Percent_Identity=31.4814814814815, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=307, Percent_Identity=37.785016286645, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI32566329, Length=302, Percent_Identity=38.0794701986755, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17561210, Length=300, Percent_Identity=37.3333333333333, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28574490, Length=271, Percent_Identity=42.0664206642066, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574488, Length=271, Percent_Identity=42.0664206642066, Blast_Score=188, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAA_SYNP2 (B1XLR4)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734613.1
- ProteinModelPortal:   B1XLR4
- SMR:   B1XLR4
- GeneID:   6056656
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1361
- HOGENOM:   HBG529885
- OMA:   KAIIDAM
- ProtClustDB:   CLSK896062
- HAMAP:   MF_01225_B
- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00729
- TIGRFAMs:   TIGR02666

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM

EC number: NA

Molecular weight: Translated: 37123; Mature: 37123

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: BINDING 8-8 BINDING 21-21 BINDING 60-60 BINDING 64-64 BINDING 91-91 BINDING 115-115 BINDING 155-155 BINDING 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVDYLRISLIDRCNFRCHYCVPDEASLQYLLTSEQLSNGEILTLLEQVFIPLGFRKFR
CCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHCCCCHHHHHHHHHHHCCCCEEEE
LTGGEPLLRPQLVPLVRAIAHLPGVEDLSMTTNAYLLADLAQDLYNAGLNRLNISLDSLN
ECCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
PETFDQIIGNRGKSRWQQTWEGIQAAHRVGFDPLKLNVVVIPGVNDQEVLDLAALTGDRH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCE
WHVRFIEFMPIGNDKLFNERAWIPSEELRQRIRAKWGLETAFVQGNGPADIFKIPGAKGT
EEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCH
LGFISQMSECFCDRCNRMRLSADGWLRPCLLNEAAQMDLKTLLRTGVPPREIRAAVKALL
HHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DQKPEINFKMRDMGTTTGQYGRTMSQIGG
CCCCCCCEEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNPVDYLRISLIDRCNFRCHYCVPDEASLQYLLTSEQLSNGEILTLLEQVFIPLGFRKFR
CCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHCCCCHHHHHHHHHHHCCCCEEEE
LTGGEPLLRPQLVPLVRAIAHLPGVEDLSMTTNAYLLADLAQDLYNAGLNRLNISLDSLN
ECCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
PETFDQIIGNRGKSRWQQTWEGIQAAHRVGFDPLKLNVVVIPGVNDQEVLDLAALTGDRH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCE
WHVRFIEFMPIGNDKLFNERAWIPSEELRQRIRAKWGLETAFVQGNGPADIFKIPGAKGT
EEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCH
LGFISQMSECFCDRCNRMRLSADGWLRPCLLNEAAQMDLKTLLRTGVPPREIRAAVKALL
HHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DQKPEINFKMRDMGTTTGQYGRTMSQIGG
CCCCCCCEEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA