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The map label for this gene is fba [H]

Identifier: 170077966

GI number: 170077966

Start: 1409072

End: 1410145

Strand: Direct

Name: fba [H]

Synonym: SYNPCC7002_A1352

Alternate gene names: 170077966

Gene position: 1409072-1410145 (Clockwise)

Preceding gene: 170077965

Following gene: 170077969

Centisome position: 46.84

GC content: 52.7

Gene sequence:

>1074_bases
ATGGCTCTCGTCCCAATGCGTTTGCTCTTAGATCACGCTGCAGAAAATAGTTATGGCATTCCTGCGTTTAACGTCAACAA
CATGGAACAGATTCTGTCCATCATGCAGGCCGCTGATGAGACCGATAGCCCCGTAATTCTCCAAGCGTCCCGTGGTGCCC
GTAGTTATGCCGGGGAAAACTTCCTCCGTCACCTCGTGCTTGCCGCCGTGGAAACCTACCCCCACATCCCCGTTGCGATG
CACCAGGATCACGGCAACAGCCCTGCCACCTGTTATTCTGCGATCCGTAACGGTTTCACCTCTGTGATGATGGACGGTTC
CCTCGAAGCCGATGCCAAAACCCCCGCTAGCTTTGACTACAACGTCAGTGTGACTGCTGAAGTTGTGAAAGTGGCCCACT
CCGTTGGTGCTTCCGTCGAAGGGGAACTCGGCTGCCTTGGCTCCCTCGAAACAGGGATGGGTGAAGCAGAAGACGGCCAC
GGTTTTGAAGGCGCTCTCAGCAAAGAACAACTTCTAACTGATCCCGACGAAGCTGTCGAATTCGTTGAGCGTACCCAAGT
AGATGCCCTTGCTGTAGCAATCGGGACCAGCCACGGTGCTTACAAATTTACCCGGAAGCCCACTGGTGAAATCCTCGCCA
TTAGCCGGATCGCTGAAATCCACGCGAAACTCCCCAACACCCACTTGGTAATGCACGGTTCTTCCTCTGTACCCCAAGAG
TGGCTCGACATGATCAATGAGTACGGTGGTGCCATTCCTGAAACCTATGGTGTACCCGTAGAAGAAATTCAAAAGGGTAT
CAAGAGCGGTGTGCGTAAAGTCAACATCGACACCGACAACCGTCTGGCGATCACTGCGGCAATTCGTGAAGCAGCGATGA
AGGATCCGAAGAACTTCGATCCCCGTCACTTCCTCAAGCCTTCGATCAAGTACATGAAGCAGGTTTGTAGCGATCGCTAT
CAGCAATTCTGGTGTGCTGGTAACGCTAGCAAGATCAAGCAAATCCCCTTAGATGAGTTTGCGAAGAAATATGCCAGCGG
TGAACTCGCAGCAAAAACTGCAGTTAGCGCCTAA

Upstream 100 bases:

>100_bases
TCGTCAAAAGGGTGAATGTATCTTAAGATTGTCAGATAAGAGAATTAATTTTCTTGACAAAATCACGAATAAAATAAGCA
AGTAAGATAGGAGGACATCT

Downstream 100 bases:

>100_bases
GTTGTAACTCCCGCCAGTCTTAGGGTTTATTCCCTAAGCTAGCTTGAATTTGAGTCCTGTTCCATGGAGATAGGGCTCAC
TTTTTTTGCTTAATTCAGGA

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase class II [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MALVPMRLLLDHAAENSYGIPAFNVNNMEQILSIMQAADETDSPVILQASRGARSYAGENFLRHLVLAAVETYPHIPVAM
HQDHGNSPATCYSAIRNGFTSVMMDGSLEADAKTPASFDYNVSVTAEVVKVAHSVGASVEGELGCLGSLETGMGEAEDGH
GFEGALSKEQLLTDPDEAVEFVERTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIAEIHAKLPNTHLVMHGSSSVPQE
WLDMINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAMKDPKNFDPRHFLKPSIKYMKQVCSDRY
QQFWCAGNASKIKQIPLDEFAKKYASGELAAKTAVSA

Sequences:

>Translated_357_residues
MALVPMRLLLDHAAENSYGIPAFNVNNMEQILSIMQAADETDSPVILQASRGARSYAGENFLRHLVLAAVETYPHIPVAM
HQDHGNSPATCYSAIRNGFTSVMMDGSLEADAKTPASFDYNVSVTAEVVKVAHSVGASVEGELGCLGSLETGMGEAEDGH
GFEGALSKEQLLTDPDEAVEFVERTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIAEIHAKLPNTHLVMHGSSSVPQE
WLDMINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAMKDPKNFDPRHFLKPSIKYMKQVCSDRY
QQFWCAGNASKIKQIPLDEFAKKYASGELAAKTAVSA
>Mature_356_residues
ALVPMRLLLDHAAENSYGIPAFNVNNMEQILSIMQAADETDSPVILQASRGARSYAGENFLRHLVLAAVETYPHIPVAMH
QDHGNSPATCYSAIRNGFTSVMMDGSLEADAKTPASFDYNVSVTAEVVKVAHSVGASVEGELGCLGSLETGMGEAEDGHG
FEGALSKEQLLTDPDEAVEFVERTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIAEIHAKLPNTHLVMHGSSSVPQEW
LDMINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAMKDPKNFDPRHFLKPSIKYMKQVCSDRYQ
QFWCAGNASKIKQIPLDEFAKKYASGELAAKTAVSA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=333, Percent_Identity=33.6336336336336, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.2188449848024, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1788072, Length=288, Percent_Identity=31.5972222222222, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789293, Length=344, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38623; Mature: 38492

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVPMRLLLDHAAENSYGIPAFNVNNMEQILSIMQAADETDSPVILQASRGARSYAGEN
CCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
FLRHLVLAAVETYPHIPVAMHQDHGNSPATCYSAIRNGFTSVMMDGSLEADAKTPASFDY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHEEECCCCCCCCCCCCCCCC
NVSVTAEVVKVAHSVGASVEGELGCLGSLETGMGEAEDGHGFEGALSKEQLLTDPDEAVE
CEEHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVERTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIAEIHAKLPNTHLVMHGSSSVPQE
HHHHHHHHHEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHH
WLDMINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAMKDPKNFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHHCCCCCCC
PRHFLKPSIKYMKQVCSDRYQQFWCAGNASKIKQIPLDEFAKKYASGELAAKTAVSA
CHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
ALVPMRLLLDHAAENSYGIPAFNVNNMEQILSIMQAADETDSPVILQASRGARSYAGEN
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
FLRHLVLAAVETYPHIPVAMHQDHGNSPATCYSAIRNGFTSVMMDGSLEADAKTPASFDY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHEEECCCCCCCCCCCCCCCC
NVSVTAEVVKVAHSVGASVEGELGCLGSLETGMGEAEDGHGFEGALSKEQLLTDPDEAVE
CEEHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVERTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIAEIHAKLPNTHLVMHGSSSVPQE
HHHHHHHHHEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHH
WLDMINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAMKDPKNFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHHCCCCCCC
PRHFLKPSIKYMKQVCSDRYQQFWCAGNASKIKQIPLDEFAKKYASGELAAKTAVSA
CHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9298645 [H]