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The map label for this gene is gyrB [H]

Identifier: 170077957

GI number: 170077957

Start: 1396012

End: 1397934

Strand: Direct

Name: gyrB [H]

Synonym: SYNPCC7002_A1343

Alternate gene names: 170077957

Gene position: 1396012-1397934 (Clockwise)

Preceding gene: 170077956

Following gene: 170077961

Centisome position: 46.41

GC content: 49.71

Gene sequence:

>1923_bases
ATGACCAGTAATTACAGTGCCCAGCAGATCCAGGTTCTCGAAGGATTAGAACCTGTCCGCAAACGTCCCGGAATGTACAT
CGGCACCACTGGTCCCCGTGGCTTACATCACCTCGTTTATGAAGTGGTTGATAACTCCGTCGATGAAGCCCTCGCCGGAT
ACTGCACAGAAATTAACGTTGAAATTAATGCCGATGGCTCCGTCACCGTCACTGATAATGGCCGCGGCATTCCCGTTGAT
GTGCACCCCAGTACCGGAAAATCAGCCCTCGAAACCGTGATGACCGTGCTCCACGCAGGCGGAAAATTTGGCGCAGGTGG
CTATAAAGTCTCCGGTGGTCTGCACGGGGTGGGCGTTTCTGTGGTTAATGCCCTCTCCGAATGGGTCGAAGTTACCGTGT
GGCGCGACGAAACCACCTACAAACAACGGTACGAACGGGGCGTCCCCCAAGGCGAACTCACCGAAGCCCCGGCCCCCCAG
CATTTATCGGGAACGTCCGTTTGTTTTTTGCCCGATGCGAAAATTTTCACTGAAACTACTGTTTTTGATTACAATACCCT
CGCCGGACGCCTGCGGGAACTGGCATATCTAAATGCTGGCGTCAGAATCGTCTTTACGGATCATCGCTCCGAAAAACAGG
CCAGTAATACTTATTTTTATGAAGGAGGCATCAAAGAATATGTCGCCTACATGAACCGCGAAAAATCGCCCCTCCATGAA
GAAATCATTTATGTCACCGGGGAAAAGAACGGTGTCCAGCTAGAAGTAGCCTTGCAATGGTGTACCGATGCTTATAGCGA
TAACCTGCTGGGTTTTGCCAACAATATTCGCACCGTTGACGGCGGGACACACCTTGAAGGCTTAAAAAGTGTCCTCACCC
GGACGATGAATACCGTTGCCCGCAAACGCAATAAGCTCAAGGATAATGATTCAAATTTGGCGGGTGAAAATATTCGTGAA
GGCTTAACCGCGGTAATTTCGGTGAAGGTGCCCGATCCAGAATTTGAAGGGCAGACGAAAACGAAGCTCGGCAACTCCGA
AGTGCGGGGGATTGTTGATTCCTTTGTGGGCGAGGTGTTAACGGAATATTTTGAATTTAATTTAAATGTTGTTGATGCGA
TTTTAGAAAAGGCAATCCAAGCCTTTAAGGCAGCAGAAGCAGCACGGCGGGCGCGGGAATTGGTGCGCCGTAAATCCGTT
TTAGAGTCTTCTTTGCTCCCCGGTAAATTAGCCGATTGTAGTGAACGAGATCCGGCGAAGACAGAAATTTATTTAGTGGA
AGGAGATTCTGCGGGCGGTAGTGCGAAACAGGGCCGCGATCGCGCCTTCCAAGCGATTTTGCCGTTGCGGGGAAAAATCC
TCAATATTGAGAAAACCGACGACGCCAAAATCTATAAAAATAATGAAATTCAGTCTCTGATCACGGCATTGGGCTTAGGG
ATTAAAGGGGAGGAATTTAACCCGGAAAAACTCCGTTACCATCGGGTGGTGATCATGACCGACGCGGACGTGGATGGAGC
GCACATTCGGACACTCCTATTAACCTTCTTCTATCGGTATCAGCGGGAATTGGTTGATCAGGGTTACATTTATATTGCCT
GCCCGCCCCTCTATAAGCTGGAACGGGGTAAAAATCACGCCTACTGTTACAGCGATCGCGAACTGCAAGATCAAATTAGC
CAGCTTCCTGATAACGCGAAATATAATATCCAACGTTTTAAGGGTCTGGGGGAAATGATGCCCCAACAGCTCTGGGACAC
CACGATGAACCCAGAAAGTCGTACCCTCAAACGCGTTGAAATTGAGGATGCGGCGGAAGCGGATCGAATCTTTACGGTAT
TGATGGGCGATCGCGTTGCCCCTCGGCGGGAGTTTATCGAGATGAATGCCCCCAAGCTGAATATGGACGATCTCGATATT
TAA

Upstream 100 bases:

>100_bases
CAGCTTGCTCCTCCCAGAAGCCTTTTATGGTATAATTTTTGCCTGATTTAACCCAAAAACAGGCTACAGAGTTTTTACGC
CCAAAATTCGGAGTTCGTCC

Downstream 100 bases:

>100_bases
TAGCAGTTTGAAATGCATAAAAAAGCCTCCTCATCATTGCGAAAAGGAGGTTTTGTTTTTTCTTTGAAATTAGTAGAAAT
TAATCGTGCATTGCTTTCGC

Product: DNA gyrase subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MTSNYSAQQIQVLEGLEPVRKRPGMYIGTTGPRGLHHLVYEVVDNSVDEALAGYCTEINVEINADGSVTVTDNGRGIPVD
VHPSTGKSALETVMTVLHAGGKFGAGGYKVSGGLHGVGVSVVNALSEWVEVTVWRDETTYKQRYERGVPQGELTEAPAPQ
HLSGTSVCFLPDAKIFTETTVFDYNTLAGRLRELAYLNAGVRIVFTDHRSEKQASNTYFYEGGIKEYVAYMNREKSPLHE
EIIYVTGEKNGVQLEVALQWCTDAYSDNLLGFANNIRTVDGGTHLEGLKSVLTRTMNTVARKRNKLKDNDSNLAGENIRE
GLTAVISVKVPDPEFEGQTKTKLGNSEVRGIVDSFVGEVLTEYFEFNLNVVDAILEKAIQAFKAAEAARRARELVRRKSV
LESSLLPGKLADCSERDPAKTEIYLVEGDSAGGSAKQGRDRAFQAILPLRGKILNIEKTDDAKIYKNNEIQSLITALGLG
IKGEEFNPEKLRYHRVVIMTDADVDGAHIRTLLLTFFYRYQRELVDQGYIYIACPPLYKLERGKNHAYCYSDRELQDQIS
QLPDNAKYNIQRFKGLGEMMPQQLWDTTMNPESRTLKRVEIEDAAEADRIFTVLMGDRVAPRREFIEMNAPKLNMDDLDI

Sequences:

>Translated_640_residues
MTSNYSAQQIQVLEGLEPVRKRPGMYIGTTGPRGLHHLVYEVVDNSVDEALAGYCTEINVEINADGSVTVTDNGRGIPVD
VHPSTGKSALETVMTVLHAGGKFGAGGYKVSGGLHGVGVSVVNALSEWVEVTVWRDETTYKQRYERGVPQGELTEAPAPQ
HLSGTSVCFLPDAKIFTETTVFDYNTLAGRLRELAYLNAGVRIVFTDHRSEKQASNTYFYEGGIKEYVAYMNREKSPLHE
EIIYVTGEKNGVQLEVALQWCTDAYSDNLLGFANNIRTVDGGTHLEGLKSVLTRTMNTVARKRNKLKDNDSNLAGENIRE
GLTAVISVKVPDPEFEGQTKTKLGNSEVRGIVDSFVGEVLTEYFEFNLNVVDAILEKAIQAFKAAEAARRARELVRRKSV
LESSLLPGKLADCSERDPAKTEIYLVEGDSAGGSAKQGRDRAFQAILPLRGKILNIEKTDDAKIYKNNEIQSLITALGLG
IKGEEFNPEKLRYHRVVIMTDADVDGAHIRTLLLTFFYRYQRELVDQGYIYIACPPLYKLERGKNHAYCYSDRELQDQIS
QLPDNAKYNIQRFKGLGEMMPQQLWDTTMNPESRTLKRVEIEDAAEADRIFTVLMGDRVAPRREFIEMNAPKLNMDDLDI
>Mature_639_residues
TSNYSAQQIQVLEGLEPVRKRPGMYIGTTGPRGLHHLVYEVVDNSVDEALAGYCTEINVEINADGSVTVTDNGRGIPVDV
HPSTGKSALETVMTVLHAGGKFGAGGYKVSGGLHGVGVSVVNALSEWVEVTVWRDETTYKQRYERGVPQGELTEAPAPQH
LSGTSVCFLPDAKIFTETTVFDYNTLAGRLRELAYLNAGVRIVFTDHRSEKQASNTYFYEGGIKEYVAYMNREKSPLHEE
IIYVTGEKNGVQLEVALQWCTDAYSDNLLGFANNIRTVDGGTHLEGLKSVLTRTMNTVARKRNKLKDNDSNLAGENIREG
LTAVISVKVPDPEFEGQTKTKLGNSEVRGIVDSFVGEVLTEYFEFNLNVVDAILEKAIQAFKAAEAARRARELVRRKSVL
ESSLLPGKLADCSERDPAKTEIYLVEGDSAGGSAKQGRDRAFQAILPLRGKILNIEKTDDAKIYKNNEIQSLITALGLGI
KGEEFNPEKLRYHRVVIMTDADVDGAHIRTLLLTFFYRYQRELVDQGYIYIACPPLYKLERGKNHAYCYSDRELQDQISQ
LPDNAKYNIQRFKGLGEMMPQQLWDTTMNPESRTLKRVEIEDAAEADRIFTVLMGDRVAPRREFIEMNAPKLNMDDLDI

Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]

COG id: COG0187

COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Homo sapiens, GI19913408, Length=610, Percent_Identity=25.0819672131148, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI19913406, Length=575, Percent_Identity=25.0434782608696, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI48994957, Length=568, Percent_Identity=54.7535211267606, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1789408, Length=632, Percent_Identity=39.7151898734177, Blast_Score=428, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17535065, Length=569, Percent_Identity=25.3075571177504, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI212645845, Length=530, Percent_Identity=25.2830188679245, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI212645657, Length=180, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324241, Length=686, Percent_Identity=23.7609329446064, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136538, Length=568, Percent_Identity=24.6478873239437, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011557
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR001241
- InterPro:   IPR013759
- InterPro:   IPR002288
- InterPro:   IPR013506
- InterPro:   IPR013760
- InterPro:   IPR018522
- InterPro:   IPR006171 [H]

Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]

EC number: =5.99.1.3 [H]

Molecular weight: Translated: 71388; Mature: 71256

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00177 TOPOISOMERASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNYSAQQIQVLEGLEPVRKRPGMYIGTTGPRGLHHLVYEVVDNSVDEALAGYCTEINV
CCCCCCHHHHHHHHCCHHHHHCCCEEEECCCCHHHHHHHHHHHHCHHHHHHHCCEEEEEE
EINADGSVTVTDNGRGIPVDVHPSTGKSALETVMTVLHAGGKFGAGGYKVSGGLHGVGVS
EEECCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHH
VVNALSEWVEVTVWRDETTYKQRYERGVPQGELTEAPAPQHLSGTSVCFLPDAKIFTETT
HHHHHHHHHEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEE
VFDYNTLAGRLRELAYLNAGVRIVFTDHRSEKQASNTYFYEGGIKEYVAYMNREKSPLHE
EEECHHHHHHHHHHHHHCCCEEEEEECCCCCHHHCCCEEEECCHHHHHHHHCCCCCCCCE
EIIYVTGEKNGVQLEVALQWCTDAYSDNLLGFANNIRTVDGGTHLEGLKSVLTRTMNTVA
EEEEEECCCCCEEEEEEEEHHHHHHCCCCEECCCCCEECCCCCHHHHHHHHHHHHHHHHH
RKRNKLKDNDSNLAGENIREGLTAVISVKVPDPEFEGQTKTKLGNSEVRGIVDSFVGEVL
HHHHCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
TEYFEFNLNVVDAILEKAIQAFKAAEAARRARELVRRKSVLESSLLPGKLADCSERDPAK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TEIYLVEGDSAGGSAKQGRDRAFQAILPLRGKILNIEKTDDAKIYKNNEIQSLITALGLG
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHHHHHHHHCCC
IKGEEFNPEKLRYHRVVIMTDADVDGAHIRTLLLTFFYRYQRELVDQGYIYIACPPLYKL
CCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
ERGKNHAYCYSDRELQDQISQLPDNAKYNIQRFKGLGEMMPQQLWDTTMNPESRTLKRVE
HCCCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEE
IEDAAEADRIFTVLMGDRVAPRREFIEMNAPKLNMDDLDI
CCCHHCHHHEEEEECCCCCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSNYSAQQIQVLEGLEPVRKRPGMYIGTTGPRGLHHLVYEVVDNSVDEALAGYCTEINV
CCCCCHHHHHHHHCCHHHHHCCCEEEECCCCHHHHHHHHHHHHCHHHHHHHCCEEEEEE
EINADGSVTVTDNGRGIPVDVHPSTGKSALETVMTVLHAGGKFGAGGYKVSGGLHGVGVS
EEECCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHH
VVNALSEWVEVTVWRDETTYKQRYERGVPQGELTEAPAPQHLSGTSVCFLPDAKIFTETT
HHHHHHHHHEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEE
VFDYNTLAGRLRELAYLNAGVRIVFTDHRSEKQASNTYFYEGGIKEYVAYMNREKSPLHE
EEECHHHHHHHHHHHHHCCCEEEEEECCCCCHHHCCCEEEECCHHHHHHHHCCCCCCCCE
EIIYVTGEKNGVQLEVALQWCTDAYSDNLLGFANNIRTVDGGTHLEGLKSVLTRTMNTVA
EEEEEECCCCCEEEEEEEEHHHHHHCCCCEECCCCCEECCCCCHHHHHHHHHHHHHHHHH
RKRNKLKDNDSNLAGENIREGLTAVISVKVPDPEFEGQTKTKLGNSEVRGIVDSFVGEVL
HHHHCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
TEYFEFNLNVVDAILEKAIQAFKAAEAARRARELVRRKSVLESSLLPGKLADCSERDPAK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TEIYLVEGDSAGGSAKQGRDRAFQAILPLRGKILNIEKTDDAKIYKNNEIQSLITALGLG
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHHHHHHHHCCC
IKGEEFNPEKLRYHRVVIMTDADVDGAHIRTLLLTFFYRYQRELVDQGYIYIACPPLYKL
CCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
ERGKNHAYCYSDRELQDQISQLPDNAKYNIQRFKGLGEMMPQQLWDTTMNPESRTLKRVE
HCCCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEE
IEDAAEADRIFTVLMGDRVAPRREFIEMNAPKLNMDDLDI
CCCHHCHHHEEEEECCCCCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2987847; 7584024; 9384377 [H]