Click here to switch to the map view.

The map label for this gene is hemA

Identifier: 170077917

GI number: 170077917

Start: 1354941

End: 1356218

Strand: Direct

Name: hemA

Synonym: SYNPCC7002_A1302

Alternate gene names: 170077917

Gene position: 1354941-1356218 (Clockwise)

Preceding gene: 170077916

Following gene: 170077918

Centisome position: 45.04

GC content: 52.66

Gene sequence:

>1278_bases
ATGAATATCGTTGTTGTTGGCCTGAGTCATAAAACAGCCCCCGTCGAAATCCGCGAAAAACTCAGTATTCAAGAAGCGAA
AATGGACGAGGCGATCGCCCACCTCAAATCCTACCCCCACGTAGAAGAAGTCGCCGTTATCAGTACCTGTAACCGCCTTG
AAATCTATGCCGTCGTGCAGGAAACAGAACAGGGCGTGCGGGAAATTTGCCAATTTCTTGCGGAAACCGGACAACTCCAA
CTCAACCGCCTGCGCCGTTACCTCTTCACCCTGCTGCACCAAGATGCCATCCGTCATCTCTTGCGAGTCGCTGCGGGCCT
AGAAAGTCTCGTTCTCGGCGAAGGCCAAATCCTCGCCCAGGTCAAAGCCGCCCACAAACTTGGTCAACAGCACAAAGGCC
TAGGGCGCTTACTCGACCGGATGTTCAAACGGGCGATCACCGCCGGGAAACGCGTCCGCAGCGAAACCAACATTGGCACC
GGGGCCGTTTCCATTAGCTCCGCCGCCGTGGAATTGGCCCAGATGAAGGTCAAGGATCTTTCCAATCAAAAAATTGCGAT
TATCGGTGCCGGGAAAATGTCGCGTCTGTTGGTGCAACACCTCGTTTCTAAAGGGGCCGAAGACATCACTATCGTCAACC
GTTCCGAACGGGGGGCGCGGGATCTCGCGAAAAAATTCCCCGATGTGGATCTGCAATTAGAATTGCTGCCAGAGATGCTC
AATGTCGTTGAACAGGCGGACATTGTCTTTACCAGTACCGGGGCGACGGAACCGATTCTTGACCGGGCGAAACTGGAAAA
TCTCGATCTTCACACGTTAATTTTGATCGATATTTCTGTGCCCCTTAACGTTGCTGCCGATGTGGAAGAAATCGCCGGCG
TGCGTTTATATAATGTGGACGCCCTCAAGGAAGTAGTGGCCCAAAACCAAGCGTCCCGCCGCAAAATGGCCGAAGAAGCC
GAAGCCCTTTTAGAAGAGGAAGTAGAAAACTATATCCAATGGTGGCAGTCCCTCGAAACCGTCCCGACCATTAGTTCCCT
ACGCAGCAAAGTCGAAAGCATTCGGGAGCAGGAGCTGGAAAAAGCCCTCTCTCGCCTCGGTGCAGAATTTGAAGAGAAGC
ACCAGGAAGTTATCGAAACCTTGACCCGGGGGATCGTTAATAAAATTCTCCATGATCCGATGGTGCAACTGCGGGCCCAA
CAGGATATTGAAGCCCGTCGAGTCTGCCTCCAATCGCTGCAAATGCTGTTTAACCTCGAAACGGAAGAGGCGATTTAG

Upstream 100 bases:

>100_bases
GACTACATTGCATAGGAAGTTAAAAAAATCCTTTAATAGAACTCTGCGCTTCCCTTGGATGTTGGAGCCCTAGAGAGATC
AAACCTTTAGAGAAAACCCC

Downstream 100 bases:

>100_bases
CAAGAGCCTAAGGCATTATTAAACCCAATAAATTTCGGTTTGAGCCGGTGTTTTCGCTAGGATGATGAACGCGGAGACTC
CGGCTCTGTAAGTTTATTTT

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MNIVVVGLSHKTAPVEIREKLSIQEAKMDEAIAHLKSYPHVEEVAVISTCNRLEIYAVVQETEQGVREICQFLAETGQLQ
LNRLRRYLFTLLHQDAIRHLLRVAAGLESLVLGEGQILAQVKAAHKLGQQHKGLGRLLDRMFKRAITAGKRVRSETNIGT
GAVSISSAAVELAQMKVKDLSNQKIAIIGAGKMSRLLVQHLVSKGAEDITIVNRSERGARDLAKKFPDVDLQLELLPEML
NVVEQADIVFTSTGATEPILDRAKLENLDLHTLILIDISVPLNVAADVEEIAGVRLYNVDALKEVVAQNQASRRKMAEEA
EALLEEEVENYIQWWQSLETVPTISSLRSKVESIREQELEKALSRLGAEFEEKHQEVIETLTRGIVNKILHDPMVQLRAQ
QDIEARRVCLQSLQMLFNLETEEAI

Sequences:

>Translated_425_residues
MNIVVVGLSHKTAPVEIREKLSIQEAKMDEAIAHLKSYPHVEEVAVISTCNRLEIYAVVQETEQGVREICQFLAETGQLQ
LNRLRRYLFTLLHQDAIRHLLRVAAGLESLVLGEGQILAQVKAAHKLGQQHKGLGRLLDRMFKRAITAGKRVRSETNIGT
GAVSISSAAVELAQMKVKDLSNQKIAIIGAGKMSRLLVQHLVSKGAEDITIVNRSERGARDLAKKFPDVDLQLELLPEML
NVVEQADIVFTSTGATEPILDRAKLENLDLHTLILIDISVPLNVAADVEEIAGVRLYNVDALKEVVAQNQASRRKMAEEA
EALLEEEVENYIQWWQSLETVPTISSLRSKVESIREQELEKALSRLGAEFEEKHQEVIETLTRGIVNKILHDPMVQLRAQ
QDIEARRVCLQSLQMLFNLETEEAI
>Mature_425_residues
MNIVVVGLSHKTAPVEIREKLSIQEAKMDEAIAHLKSYPHVEEVAVISTCNRLEIYAVVQETEQGVREICQFLAETGQLQ
LNRLRRYLFTLLHQDAIRHLLRVAAGLESLVLGEGQILAQVKAAHKLGQQHKGLGRLLDRMFKRAITAGKRVRSETNIGT
GAVSISSAAVELAQMKVKDLSNQKIAIIGAGKMSRLLVQHLVSKGAEDITIVNRSERGARDLAKKFPDVDLQLELLPEML
NVVEQADIVFTSTGATEPILDRAKLENLDLHTLILIDISVPLNVAADVEEIAGVRLYNVDALKEVVAQNQASRRKMAEEA
EALLEEEVENYIQWWQSLETVPTISSLRSKVESIREQELEKALSRLGAEFEEKHQEVIETLTRGIVNKILHDPMVQLRAQ
QDIEARRVCLQSLQMLFNLETEEAI

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family

Homologues:

Organism=Escherichia coli, GI1787461, Length=402, Percent_Identity=34.0796019900498, Blast_Score=220, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HEM1_SYNP2 (B1XLK6)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734555.1
- ProteinModelPortal:   B1XLK6
- SMR:   B1XLK6
- GeneID:   6056400
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1302
- HOGENOM:   HBG732626
- OMA:   GPILNRL
- ProtClustDB:   PRK00045
- GO:   GO:0005737
- HAMAP:   MF_00087
- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000445
- TIGRFAMs:   TIGR01035

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH; SSF69075 4pyrrol_synth_GluRdtase_C; SSF69742 GlutR

EC number: =1.2.1.70

Molecular weight: Translated: 47549; Mature: 47549

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00747 GLUTR

Important sites: ACT_SITE 50-50 BINDING 109-109 BINDING 120-120

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVVVGLSHKTAPVEIREKLSIQEAKMDEAIAHLKSYPHVEEVAVISTCNRLEIYAVVQ
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHH
ETEQGVREICQFLAETGQLQLNRLRRYLFTLLHQDAIRHLLRVAAGLESLVLGEGQILAQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VKAAHKLGQQHKGLGRLLDRMFKRAITAGKRVRSETNIGTGAVSISSAAVELAQMKVKDL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
SNQKIAIIGAGKMSRLLVQHLVSKGAEDITIVNRSERGARDLAKKFPDVDLQLELLPEML
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHH
NVVEQADIVFTSTGATEPILDRAKLENLDLHTLILIDISVPLNVAADVEEIAGVRLYNVD
HHHHHCCEEEECCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHCCCEEECHH
ALKEVVAQNQASRRKMAEEAEALLEEEVENYIQWWQSLETVPTISSLRSKVESIREQELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KALSRLGAEFEEKHQEVIETLTRGIVNKILHDPMVQLRAQQDIEARRVCLQSLQMLFNLE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
TEEAI
HHCCC
>Mature Secondary Structure
MNIVVVGLSHKTAPVEIREKLSIQEAKMDEAIAHLKSYPHVEEVAVISTCNRLEIYAVVQ
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHH
ETEQGVREICQFLAETGQLQLNRLRRYLFTLLHQDAIRHLLRVAAGLESLVLGEGQILAQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VKAAHKLGQQHKGLGRLLDRMFKRAITAGKRVRSETNIGTGAVSISSAAVELAQMKVKDL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
SNQKIAIIGAGKMSRLLVQHLVSKGAEDITIVNRSERGARDLAKKFPDVDLQLELLPEML
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHH
NVVEQADIVFTSTGATEPILDRAKLENLDLHTLILIDISVPLNVAADVEEIAGVRLYNVD
HHHHHCCEEEECCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHCCCEEECHH
ALKEVVAQNQASRRKMAEEAEALLEEEVENYIQWWQSLETVPTISSLRSKVESIREQELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KALSRLGAEFEEKHQEVIETLTRGIVNKILHDPMVQLRAQQDIEARRVCLQSLQMLFNLE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
TEEAI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA