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The map label for this gene is mscS [H]

Identifier: 170077794

GI number: 170077794

Start: 1217839

End: 1219476

Strand: Direct

Name: mscS [H]

Synonym: SYNPCC7002_A1177

Alternate gene names: 170077794

Gene position: 1217839-1219476 (Clockwise)

Preceding gene: 170077787

Following gene: 170077795

Centisome position: 40.49

GC content: 45.79

Gene sequence:

>1638_bases
ATGAATGGGATCCTCCTCGATCTTGGTGTGGTGATCGCCGAGATTATTCTCTTTTTAATCGCGATCACTGTGGGACAATT
TTTAATTATTTTGACCCTGAAACGTCTAGCCCAATGGGTGCCAGAAAAACAAGGACAAAATCCCCTAAATTTAACCCAAA
AAATCCTTAATAAATCCCTCTTCGTCATTAAGATCACCGGGGCCATAATCATTGCTGCCTTAAATGGTTATTTATTCCTT
CAACAAAAATCCCCTTACCTTTATCTCCTTGATTTAATTAACGGCATCTCTCCGGAACAGTGGCAAAGGCTCGCCCTCGG
TTTATTAAAAAGTGTTTTACTTCTGTTGCTCGTGAGTTTAATGATCGCTTCTCTGCGGCCACGCTTGAAACGGGCTGGCG
ATCGCCTCAAAGCTTGGAAAAATATCGAAGGCAATAACCACAGCTTAGATACGCTCTTTAAGGCCATTGATTTGGCGATC
GCCAATGGTCTTTGGATTTTGGCCCTGGTGGTGTGCCTCAATTTTTTGTTTGTCCCTCCGAGCATTACCCAATATTTTTA
TCTCGCGATCAAAGTTTATTTTTTGCTTTGCTTTGGGATCATTGCTGTGCGGGCATCGTTTTCTTTGCTGGATACTTTAG
ATGGTTTATCAACGGAATTTATTGCCAAACATCCCCGGTCTCCCCTGCGATTTTACCCCCGGTTTCGTTATTTATTGGGC
CTCACAAAACGTTGTTTAGAAACGGGCATTTATCTGGCGATCGCCGGAGTGATTTGTGCCCAATTTCCCCTACTCGATCA
CATTGCCCCCTATGCGATCCCGGCGAATCAAATTATCCTGATTATTTTCATCGCGGCCCTGGTGATCGAACTGAGCAATA
TCATTGTCGAAAAATTATTGTTGCGATCGCCAAACCTCAGTCCTGTCCAACAACGCCGTCGTTTAACCTTTATCCCCCTG
GTGCAAAACACCGTACGCTACTGCATTTATTTTGTGAGTGGCGTTTCAATTCTCTATGTCTTTGACATTGACCCGACACC
GATCCTCGCCGGGGCCGGGATCTTGGGTTTAGCAGTGGGGCTTGGGGCGCAAAATTTAATCAATGACCTCGTCAATGGCT
TTTCCATTTTGTTGCAAAATTACTACCTTGTCGGTGATTTTGTCGAAACGGATAATGCCACAGGCCTTGTCGAAGAAATG
GATCTGCGGGTCACACGCATCCGCGATACAGGGGGACGGCTACATATCATCCGCAATGGCGACATCAAGACCATTGTGAA
TTACTCCAAAGATTATGTGTATTCGGTGGTTTATGTTGGGGTCGCTTACGACTCAGATTTAGACCATGTGTATCAGGTTC
TAGGGGATGTGGGCCACCAAATTCAAGGCTTACACCCTGATGTGCTCGAACCGACCCGCATTGATGGCCTCGATAACTTT
GCCGAATCTGAACTCACCATCCGCACGGTTACCAAGGTGAAACCAGGAAAACATCTACCGGTGCAGCGTCTCCTGCGGAA
GTTAATCAAAGAAGCCTTCGACCGCGAACAGATCGAAATTCCCTTTGCCCGCCGTGTACTCATCTTCAAAAATGAAGCCC
CTGACCTCGATTCACTTCGAGATTCGGAAAATATGTAA

Upstream 100 bases:

>100_bases
TATGGGATGGTGTTTTTGCTAAGTTGAAGCCGAGATTGTTAAAAAAAAGAACTAACCGCAATCTCGAATTTCAGTCAAAA
ACGGTGCAAAGACAGAAAAC

Downstream 100 bases:

>100_bases
GACTTTTGTAATAGCTGGGCTCAAAATAGGCGAAATTCAGTCTAATGGGAGCAGTAGTTGTCTAAAATCCAAGATTATTT
GTCATGTCTAAAGCTGCCTT

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNGILLDLGVVIAEIILFLIAITVGQFLIILTLKRLAQWVPEKQGQNPLNLTQKILNKSLFVIKITGAIIIAALNGYLFL
QQKSPYLYLLDLINGISPEQWQRLALGLLKSVLLLLLVSLMIASLRPRLKRAGDRLKAWKNIEGNNHSLDTLFKAIDLAI
ANGLWILALVVCLNFLFVPPSITQYFYLAIKVYFLLCFGIIAVRASFSLLDTLDGLSTEFIAKHPRSPLRFYPRFRYLLG
LTKRCLETGIYLAIAGVICAQFPLLDHIAPYAIPANQIILIIFIAALVIELSNIIVEKLLLRSPNLSPVQQRRRLTFIPL
VQNTVRYCIYFVSGVSILYVFDIDPTPILAGAGILGLAVGLGAQNLINDLVNGFSILLQNYYLVGDFVETDNATGLVEEM
DLRVTRIRDTGGRLHIIRNGDIKTIVNYSKDYVYSVVYVGVAYDSDLDHVYQVLGDVGHQIQGLHPDVLEPTRIDGLDNF
AESELTIRTVTKVKPGKHLPVQRLLRKLIKEAFDREQIEIPFARRVLIFKNEAPDLDSLRDSENM

Sequences:

>Translated_545_residues
MNGILLDLGVVIAEIILFLIAITVGQFLIILTLKRLAQWVPEKQGQNPLNLTQKILNKSLFVIKITGAIIIAALNGYLFL
QQKSPYLYLLDLINGISPEQWQRLALGLLKSVLLLLLVSLMIASLRPRLKRAGDRLKAWKNIEGNNHSLDTLFKAIDLAI
ANGLWILALVVCLNFLFVPPSITQYFYLAIKVYFLLCFGIIAVRASFSLLDTLDGLSTEFIAKHPRSPLRFYPRFRYLLG
LTKRCLETGIYLAIAGVICAQFPLLDHIAPYAIPANQIILIIFIAALVIELSNIIVEKLLLRSPNLSPVQQRRRLTFIPL
VQNTVRYCIYFVSGVSILYVFDIDPTPILAGAGILGLAVGLGAQNLINDLVNGFSILLQNYYLVGDFVETDNATGLVEEM
DLRVTRIRDTGGRLHIIRNGDIKTIVNYSKDYVYSVVYVGVAYDSDLDHVYQVLGDVGHQIQGLHPDVLEPTRIDGLDNF
AESELTIRTVTKVKPGKHLPVQRLLRKLIKEAFDREQIEIPFARRVLIFKNEAPDLDSLRDSENM
>Mature_545_residues
MNGILLDLGVVIAEIILFLIAITVGQFLIILTLKRLAQWVPEKQGQNPLNLTQKILNKSLFVIKITGAIIIAALNGYLFL
QQKSPYLYLLDLINGISPEQWQRLALGLLKSVLLLLLVSLMIASLRPRLKRAGDRLKAWKNIEGNNHSLDTLFKAIDLAI
ANGLWILALVVCLNFLFVPPSITQYFYLAIKVYFLLCFGIIAVRASFSLLDTLDGLSTEFIAKHPRSPLRFYPRFRYLLG
LTKRCLETGIYLAIAGVICAQFPLLDHIAPYAIPANQIILIIFIAALVIELSNIIVEKLLLRSPNLSPVQQRRRLTFIPL
VQNTVRYCIYFVSGVSILYVFDIDPTPILAGAGILGLAVGLGAQNLINDLVNGFSILLQNYYLVGDFVETDNATGLVEEM
DLRVTRIRDTGGRLHIIRNGDIKTIVNYSKDYVYSVVYVGVAYDSDLDHVYQVLGDVGHQIQGLHPDVLEPTRIDGLDNF
AESELTIRTVTKVKPGKHLPVQRLLRKLIKEAFDREQIEIPFARRVLIFKNEAPDLDSLRDSENM

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=268, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081787, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 61170; Mature: 61170

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGILLDLGVVIAEIILFLIAITVGQFLIILTLKRLAQWVPEKQGQNPLNLTQKILNKSL
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCE
FVIKITGAIIIAALNGYLFLQQKSPYLYLLDLINGISPEQWQRLALGLLKSVLLLLLVSL
EEEEEHHHHHHHHHCCEEEEECCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MIASLRPRLKRAGDRLKAWKNIEGNNHSLDTLFKAIDLAIANGLWILALVVCLNFLFVPP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SITQYFYLAIKVYFLLCFGIIAVRASFSLLDTLDGLSTEFIAKHPRSPLRFYPRFRYLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHH
LTKRCLETGIYLAIAGVICAQFPLLDHIAPYAIPANQIILIIFIAALVIELSNIIVEKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSPNLSPVQQRRRLTFIPLVQNTVRYCIYFVSGVSILYVFDIDPTPILAGAGILGLAVG
HCCCCCCHHHHHCCCEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHCCHHHHHHHH
LGAQNLINDLVNGFSILLQNYYLVGDFVETDNATGLVEEMDLRVTRIRDTGGRLHIIRNG
CCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHCCEEEEEECCCCEEEEEECC
DIKTIVNYSKDYVYSVVYVGVAYDSDLDHVYQVLGDVGHQIQGLHPDVLEPTRIDGLDNF
CCHHHHHCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
AESELTIRTVTKVKPGKHLPVQRLLRKLIKEAFDREQIEIPFARRVLIFKNEAPDLDSLR
HCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHCEEEEEECCCCCHHHCC
DSENM
CCCCC
>Mature Secondary Structure
MNGILLDLGVVIAEIILFLIAITVGQFLIILTLKRLAQWVPEKQGQNPLNLTQKILNKSL
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCE
FVIKITGAIIIAALNGYLFLQQKSPYLYLLDLINGISPEQWQRLALGLLKSVLLLLLVSL
EEEEEHHHHHHHHHCCEEEEECCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MIASLRPRLKRAGDRLKAWKNIEGNNHSLDTLFKAIDLAIANGLWILALVVCLNFLFVPP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SITQYFYLAIKVYFLLCFGIIAVRASFSLLDTLDGLSTEFIAKHPRSPLRFYPRFRYLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHH
LTKRCLETGIYLAIAGVICAQFPLLDHIAPYAIPANQIILIIFIAALVIELSNIIVEKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSPNLSPVQQRRRLTFIPLVQNTVRYCIYFVSGVSILYVFDIDPTPILAGAGILGLAVG
HCCCCCCHHHHHCCCEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHCCHHHHHHHH
LGAQNLINDLVNGFSILLQNYYLVGDFVETDNATGLVEEMDLRVTRIRDTGGRLHIIRNG
CCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHCCEEEEEECCCCEEEEEECC
DIKTIVNYSKDYVYSVVYVGVAYDSDLDHVYQVLGDVGHQIQGLHPDVLEPTRIDGLDNF
CCHHHHHCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
AESELTIRTVTKVKPGKHLPVQRLLRKLIKEAFDREQIEIPFARRVLIFKNEAPDLDSLR
HCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHCEEEEEECCCCCHHHCC
DSENM
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]