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The map label for this gene is ecaA [H]

Identifier: 170077716

GI number: 170077716

Start: 1125815

End: 1126615

Strand: Direct

Name: ecaA [H]

Synonym: SYNPCC7002_A1096

Alternate gene names: 170077716

Gene position: 1125815-1126615 (Clockwise)

Preceding gene: 170077715

Following gene: 170077720

Centisome position: 37.43

GC content: 51.69

Gene sequence:

>801_bases
ATGTTAAGGCGAGTGATTTTGGCGATCGCCATTGCCTTATGGTGGGGTCTATGGGTTGTTTGGGCGGCGCCTCAATCGCA
GTTTTTGACAATCGCAAAAACCGTCGCAACCCCTTGGAATTACGCAGATCTTGGCCCCCAGCGGTGGGGCGAGTTGCAAC
CAGAGTTCCAGACCTGTGCCATTGGCGAAACCCAATCACCCTTGGCGCTTTTTCCTGAATCGTCTACTCCAGTTTCGGGG
GCGTCGCTGCCTTGGCAGTATCAACCGAGTCTCGGGCTTATCCAGGCGACCAGTACCACTTTACAAATCCAAGTCACGGG
GAATAACACCCTACAAATCGGCGTTGATCTTTACAAGCTTGAGCAAATTCATTTTCATTATCCCAGTGAGCACCATGTCC
AGGGAAAACAATATGCCATGGAAGTTCACTTTGTCCATCGGCGTGCCACCCAAGGAGCCGCTGTTTTGGCGGTACTGGTT
GAACCTGGAGCGATCAATCCGACGTTCACCCATATTTTGCAACGGTGGCCGACCCAAGCCCATCCCAGTCAGGTGATTCA
CTTCGATCCGGCGGCATTACTCCCCCAAGGCGATCGCCCTTATTTCCATTATCTTGGTTCTTTAACCACGCCCCCTTGCA
CGGAAGGAATTCGCTGGTTAGTTTTCGCACAACCCATTGCCTTAGGGGCAGCGCAAATCGAATATTACCAAGCTCTGTAT
GCACCAAATGCCCGCCCCCGACAAACAATGACGACCCATCAAGTGCAATATTATGTTCCCGGTCAGGAAACGAAAAATTA
G

Upstream 100 bases:

>100_bases
GCTTAATTTTTAAAGCTATTTTTGGCTAATTTTGATGGGAGCTGTGGTCACCATGGCTCTTTTTTATTGTTTAGAGGTTT
CAGGGAAAGGATTTGGAATC

Downstream 100 bases:

>100_bases
GCTACTTTAACAAAAATATTCTCACCTTCTTGGCGGACTTCGTAGCGAGATAAACCGGCGGTGGCTGGCCCCTGAAGCAA
TTCACCATCCAAGGCAAACC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLRRVILAIAIALWWGLWVVWAAPQSQFLTIAKTVATPWNYADLGPQRWGELQPEFQTCAIGETQSPLALFPESSTPVSG
ASLPWQYQPSLGLIQATSTTLQIQVTGNNTLQIGVDLYKLEQIHFHYPSEHHVQGKQYAMEVHFVHRRATQGAAVLAVLV
EPGAINPTFTHILQRWPTQAHPSQVIHFDPAALLPQGDRPYFHYLGSLTTPPCTEGIRWLVFAQPIALGAAQIEYYQALY
APNARPRQTMTTHQVQYYVPGQETKN

Sequences:

>Translated_266_residues
MLRRVILAIAIALWWGLWVVWAAPQSQFLTIAKTVATPWNYADLGPQRWGELQPEFQTCAIGETQSPLALFPESSTPVSG
ASLPWQYQPSLGLIQATSTTLQIQVTGNNTLQIGVDLYKLEQIHFHYPSEHHVQGKQYAMEVHFVHRRATQGAAVLAVLV
EPGAINPTFTHILQRWPTQAHPSQVIHFDPAALLPQGDRPYFHYLGSLTTPPCTEGIRWLVFAQPIALGAAQIEYYQALY
APNARPRQTMTTHQVQYYVPGQETKN
>Mature_266_residues
MLRRVILAIAIALWWGLWVVWAAPQSQFLTIAKTVATPWNYADLGPQRWGELQPEFQTCAIGETQSPLALFPESSTPVSG
ASLPWQYQPSLGLIQATSTTLQIQVTGNNTLQIGVDLYKLEQIHFHYPSEHHVQGKQYAMEVHFVHRRATQGAAVLAVLV
EPGAINPTFTHILQRWPTQAHPSQVIHFDPAALLPQGDRPYFHYLGSLTTPPCTEGIRWLVFAQPIALGAAQIEYYQALY
APNARPRQTMTTHQVQYYVPGQETKN

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG3338

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-carbonic anhydrase family [H]

Homologues:

Organism=Homo sapiens, GI45935383, Length=293, Percent_Identity=28.6689419795222, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI4502515, Length=293, Percent_Identity=28.6689419795222, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4885101, Length=259, Percent_Identity=31.2741312741313, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4885099, Length=237, Percent_Identity=30.379746835443, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4557395, Length=268, Percent_Identity=28.7313432835821, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI258679498, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI192447434, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI192447432, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI192447430, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI4502517, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI38348436, Length=258, Percent_Identity=29.0697674418605, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI62240989, Length=169, Percent_Identity=31.9526627218935, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502519, Length=173, Percent_Identity=32.9479768786127, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI6005723, Length=234, Percent_Identity=26.4957264957265, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI169636420, Length=137, Percent_Identity=36.4963503649635, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI70167127, Length=238, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI22027500, Length=231, Percent_Identity=28.1385281385281, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4502521, Length=143, Percent_Identity=32.1678321678322, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI6912284, Length=249, Percent_Identity=28.9156626506024, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17568715, Length=254, Percent_Identity=25.1968503937008, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71995280, Length=168, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737413, Length=239, Percent_Identity=29.2887029288703, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24650523, Length=265, Percent_Identity=24.5283018867925, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116008410, Length=257, Percent_Identity=26.8482490272374, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001148
- InterPro:   IPR018338
- InterPro:   IPR018340
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00194 Carb_anhydrase [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 29828; Mature: 29828

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00162 ALPHA_CA_1 ; PS51144 ALPHA_CA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRVILAIAIALWWGLWVVWAAPQSQFLTIAKTVATPWNYADLGPQRWGELQPEFQTCA
CHHHHHHHHHHHHHHHHHEEEECCCHHHEEHHHHHCCCCCCCCCCHHHHCCCCCCCCEEE
IGETQSPLALFPESSTPVSGASLPWQYQPSLGLIQATSTTLQIQVTGNNTLQIGVDLYKL
CCCCCCCEEECCCCCCCCCCCCCCEEECCCCCEEEECCEEEEEEEECCCEEEEEEEEEEE
EQIHFHYPSEHHVQGKQYAMEVHFVHRRATQGAAVLAVLVEPGAINPTFTHILQRWPTQA
EEEEEECCCCCCCCCHHEEEEEEEEHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
HPSQVIHFDPAALLPQGDRPYFHYLGSLTTPPCTEGIRWLVFAQPIALGAAQIEYYQALY
CCCEEEEECCHHHCCCCCCCHHHHCCCCCCCCHHHCCEEEEEECCHHHHHHHHHHHHHHH
APNARPRQTMTTHQVQYYVPGQETKN
CCCCCCCCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MLRRVILAIAIALWWGLWVVWAAPQSQFLTIAKTVATPWNYADLGPQRWGELQPEFQTCA
CHHHHHHHHHHHHHHHHHEEEECCCHHHEEHHHHHCCCCCCCCCCHHHHCCCCCCCCEEE
IGETQSPLALFPESSTPVSGASLPWQYQPSLGLIQATSTTLQIQVTGNNTLQIGVDLYKL
CCCCCCCEEECCCCCCCCCCCCCCEEECCCCCEEEECCEEEEEEEECCCEEEEEEEEEEE
EQIHFHYPSEHHVQGKQYAMEVHFVHRRATQGAAVLAVLVEPGAINPTFTHILQRWPTQA
EEEEEECCCCCCCCCHHEEEEEEEEHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
HPSQVIHFDPAALLPQGDRPYFHYLGSLTTPPCTEGIRWLVFAQPIALGAAQIEYYQALY
CCCEEEEECCHHHCCCCCCCHHHHCCCCCCCCHHHCCEEEEEECCHHHHHHHHHHHHHHH
APNARPRQTMTTHQVQYYVPGQETKN
CCCCCCCCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006032; 11759840 [H]