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The map label for this gene is pgi [H]

Identifier: 170077585

GI number: 170077585

Start: 992954

End: 994540

Strand: Direct

Name: pgi [H]

Synonym: SYNPCC7002_A0964

Alternate gene names: 170077585

Gene position: 992954-994540 (Clockwise)

Preceding gene: 170077583

Following gene: 170077587

Centisome position: 33.01

GC content: 50.22

Gene sequence:

>1587_bases
ATGGATACCGCCGCACTCTGGCAACGTTACCAAGCTTGGCTCTACTACCATCCGGAACTCGAATTTTACGTCGATATCAG
TCGGATGGGCTTTGATGAGGCGTTTGTACAAGGTTTACAACCGAAGTTTGCAAAGGCATTTCAAGATTTAAAAGCGATCG
AAGCCGGGGCGATCGCCAACCCCGATGAAGGCAGAATGGTGGGTCACTATTGGTTGCGTAACCCTGATCTCGCCCCCAAT
GCGGAACTAAAAGCAGATATTGTTGACACCCTCGAAAAAGTCGAAAAATTTGCCAAGGCAGTTCATGCGGGAGAAATTAC
GGCTCCCGGTGGTGTGCCGTTTACAGATATTCTCTCCATTGGCATTGGCGGGTCTGCCCTCGGCCCCCAATTTGTCGCCG
AAGCCCTCGCCGATGTGGATGCGCCGTTAAAGATCCATTTCATCGATAACACCGATCCCGACGGCATTGACCGCACCCTC
GCCCAGGTCAAAGATCGACTGAATACCACCTTGGCGATCGTCATTTCTAAATCTGGCGGTACCCCCGAAACCCGGAACAG
CATGGTTGAGGTAAAAAATTTCTACAAAGCCCACAAAATTGATTTCTCTTCCCATGCAGTAGCGATTACCGGAATTGGCT
CCAAACTCGAAAATGTGGCGAAATCCGAGCATTGGCTGACCACCTTCCCGATGCATGACTGGGTGGGCGGTCGGACTTCC
GAATTGTCAGCCGTGGGTTTAGTTGCCGCCGCGTTACAAGGGATTAATATTCGGGCAATGCTTGACGGCGCAAAAACTAT
GGACGATGCCACCCGCATTCCTGAACTAAAACAAAATCCGGCGGCATTATTGGCTCTGGCTTGGTATTACTCCGGCAATG
GCAGGGGCGAGAAGGATATGGTGATTTTGCCCTATAAAGACCGTTTATTGCTCTTTAGTCGCTATTTGCAGCAACTGATC
ATGGAATCCCTCGGCAAAGAAGAGGATCTCGATGGCAATAAGGTCTACCAAGGAATTGCTGTTTACGGGAATAAAGGTTC
CACTGACCAGCACGCCTATGTGCAACAACTGCGAGAAGGGGTTCCCAATTTCTTCGCGACCTTTATCGAAGTGTTAGGCG
ATCGCCAAGGCAATTCCATTGATATTGAAAATGGCGCAACCAGCGGTGATTTTCTGTCTGGCTTTTTGCTCGGCACCCGC
GAAGCCCTCTATGACAATGGCAGGGACTCGATCACCATTACCGTTCCCGATGTCGATGCCCGTACTGTCGGTGCCCTGAT
TGCCCTCTATGAACGGGCTGTCACGATCTATGCGTCTTTGGTCAATATCAACGCTTACCACCAACCTGGCGTCGAAGCTG
GGAAAAAAGCAGCAGCATCAGTGCTCGATCTTCAGAAAAAAGTGGTGGATGCGGTAACGACGAGTGAGTCTTCTCTGACC
CTCGATAGTCTAGCGATTAAAGTCGGGGCAATTGAACAAATTGAGGTGATTTACAAAATTGTCCGTCATCTGGCTGCCAA
TGGTCGCGCCTTGAAATTAGAGGGCAATCCGGCTCAACCTAGTGCGCTAAAGATTAGTCGTCTCTAA

Upstream 100 bases:

>100_bases
AAAACTGAATACTAAACAATGTGAATTGCTACATAAATCGGCGCCAGCCTCTAGTTAAACTTAACGTAAATCATCAAAAA
ACAGGTTGAGAAGTTTATAT

Downstream 100 bases:

>100_bases
GTTCAGAATGTCTCACATTCAAGCTATGGCTGACCTGTCACGCGCTCCAGGATAAAGAAAAATGGCTGGGTAGATTGCTT
GAAATCCATCACGCCAAAAA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MDTAALWQRYQAWLYYHPELEFYVDISRMGFDEAFVQGLQPKFAKAFQDLKAIEAGAIANPDEGRMVGHYWLRNPDLAPN
AELKADIVDTLEKVEKFAKAVHAGEITAPGGVPFTDILSIGIGGSALGPQFVAEALADVDAPLKIHFIDNTDPDGIDRTL
AQVKDRLNTTLAIVISKSGGTPETRNSMVEVKNFYKAHKIDFSSHAVAITGIGSKLENVAKSEHWLTTFPMHDWVGGRTS
ELSAVGLVAAALQGINIRAMLDGAKTMDDATRIPELKQNPAALLALAWYYSGNGRGEKDMVILPYKDRLLLFSRYLQQLI
MESLGKEEDLDGNKVYQGIAVYGNKGSTDQHAYVQQLREGVPNFFATFIEVLGDRQGNSIDIENGATSGDFLSGFLLGTR
EALYDNGRDSITITVPDVDARTVGALIALYERAVTIYASLVNINAYHQPGVEAGKKAAASVLDLQKKVVDAVTTSESSLT
LDSLAIKVGAIEQIEVIYKIVRHLAANGRALKLEGNPAQPSALKISRL

Sequences:

>Translated_528_residues
MDTAALWQRYQAWLYYHPELEFYVDISRMGFDEAFVQGLQPKFAKAFQDLKAIEAGAIANPDEGRMVGHYWLRNPDLAPN
AELKADIVDTLEKVEKFAKAVHAGEITAPGGVPFTDILSIGIGGSALGPQFVAEALADVDAPLKIHFIDNTDPDGIDRTL
AQVKDRLNTTLAIVISKSGGTPETRNSMVEVKNFYKAHKIDFSSHAVAITGIGSKLENVAKSEHWLTTFPMHDWVGGRTS
ELSAVGLVAAALQGINIRAMLDGAKTMDDATRIPELKQNPAALLALAWYYSGNGRGEKDMVILPYKDRLLLFSRYLQQLI
MESLGKEEDLDGNKVYQGIAVYGNKGSTDQHAYVQQLREGVPNFFATFIEVLGDRQGNSIDIENGATSGDFLSGFLLGTR
EALYDNGRDSITITVPDVDARTVGALIALYERAVTIYASLVNINAYHQPGVEAGKKAAASVLDLQKKVVDAVTTSESSLT
LDSLAIKVGAIEQIEVIYKIVRHLAANGRALKLEGNPAQPSALKISRL
>Mature_528_residues
MDTAALWQRYQAWLYYHPELEFYVDISRMGFDEAFVQGLQPKFAKAFQDLKAIEAGAIANPDEGRMVGHYWLRNPDLAPN
AELKADIVDTLEKVEKFAKAVHAGEITAPGGVPFTDILSIGIGGSALGPQFVAEALADVDAPLKIHFIDNTDPDGIDRTL
AQVKDRLNTTLAIVISKSGGTPETRNSMVEVKNFYKAHKIDFSSHAVAITGIGSKLENVAKSEHWLTTFPMHDWVGGRTS
ELSAVGLVAAALQGINIRAMLDGAKTMDDATRIPELKQNPAALLALAWYYSGNGRGEKDMVILPYKDRLLLFSRYLQQLI
MESLGKEEDLDGNKVYQGIAVYGNKGSTDQHAYVQQLREGVPNFFATFIEVLGDRQGNSIDIENGATSGDFLSGFLLGTR
EALYDNGRDSITITVPDVDARTVGALIALYERAVTIYASLVNINAYHQPGVEAGKKAAASVLDLQKKVVDAVTTSESSLT
LDSLAIKVGAIEQIEVIYKIVRHLAANGRALKLEGNPAQPSALKISRL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=480, Percent_Identity=29.5833333333333, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI296080693, Length=480, Percent_Identity=27.0833333333333, Blast_Score=124, Evalue=3e-28,
Organism=Escherichia coli, GI1790457, Length=461, Percent_Identity=31.4533622559653, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71996708, Length=505, Percent_Identity=29.3069306930693, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71996703, Length=505, Percent_Identity=29.3069306930693, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319673, Length=435, Percent_Identity=29.6551724137931, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24651916, Length=464, Percent_Identity=29.9568965517241, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24651914, Length=464, Percent_Identity=29.9568965517241, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17737445, Length=464, Percent_Identity=29.9568965517241, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 57435; Mature: 57435

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTAALWQRYQAWLYYHPELEFYVDISRMGFDEAFVQGLQPKFAKAFQDLKAIEAGAIAN
CCHHHHHHHHHEEEEECCCEEEEEEHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
PDEGRMVGHYWLRNPDLAPNAELKADIVDTLEKVEKFAKAVHAGEITAPGGVPFTDILSI
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GIGGSALGPQFVAEALADVDAPLKIHFIDNTDPDGIDRTLAQVKDRLNTTLAIVISKSGG
CCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
TPETRNSMVEVKNFYKAHKIDFSSHAVAITGIGSKLENVAKSEHWLTTFPMHDWVGGRTS
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCEEECCCHHCCCCCCC
ELSAVGLVAAALQGINIRAMLDGAKTMDDATRIPELKQNPAALLALAWYYSGNGRGEKDM
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCHHEEEEEEEEECCCCCCCCE
VILPYKDRLLLFSRYLQQLIMESLGKEEDLDGNKVYQGIAVYGNKGSTDQHAYVQQLREG
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCCCHHHHHHHHHHHC
VPNFFATFIEVLGDRQGNSIDIENGATSGDFLSGFLLGTREALYDNGRDSITITVPDVDA
CHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
RTVGALIALYERAVTIYASLVNINAYHQPGVEAGKKAAASVLDLQKKVVDAVTTSESSLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LDSLAIKVGAIEQIEVIYKIVRHLAANGRALKLEGNPAQPSALKISRL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECC
>Mature Secondary Structure
MDTAALWQRYQAWLYYHPELEFYVDISRMGFDEAFVQGLQPKFAKAFQDLKAIEAGAIAN
CCHHHHHHHHHEEEEECCCEEEEEEHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
PDEGRMVGHYWLRNPDLAPNAELKADIVDTLEKVEKFAKAVHAGEITAPGGVPFTDILSI
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GIGGSALGPQFVAEALADVDAPLKIHFIDNTDPDGIDRTLAQVKDRLNTTLAIVISKSGG
CCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
TPETRNSMVEVKNFYKAHKIDFSSHAVAITGIGSKLENVAKSEHWLTTFPMHDWVGGRTS
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCEEECCCHHCCCCCCC
ELSAVGLVAAALQGINIRAMLDGAKTMDDATRIPELKQNPAALLALAWYYSGNGRGEKDM
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCHHEEEEEEEEECCCCCCCCE
VILPYKDRLLLFSRYLQQLIMESLGKEEDLDGNKVYQGIAVYGNKGSTDQHAYVQQLREG
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCCCHHHHHHHHHHHC
VPNFFATFIEVLGDRQGNSIDIENGATSGDFLSGFLLGTREALYDNGRDSITITVPDVDA
CHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
RTVGALIALYERAVTIYASLVNINAYHQPGVEAGKKAAASVLDLQKKVVDAVTTSESSLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LDSLAIKVGAIEQIEVIYKIVRHLAANGRALKLEGNPAQPSALKISRL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA