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The map label for this gene is pyrB [H]

Identifier: 170077506

GI number: 170077506

Start: 912665

End: 913687

Strand: Direct

Name: pyrB [H]

Synonym: SYNPCC7002_A0884

Alternate gene names: 170077506

Gene position: 912665-913687 (Clockwise)

Preceding gene: 170077505

Following gene: 170077516

Centisome position: 30.34

GC content: 53.96

Gene sequence:

>1023_bases
ATGGGAACAGTTATGACAACGGCAACGGCCACCTGGACAAGGCGACATATTCTGTCACTGATGGATTTTTCGGTGGCGGA
ACTGGATGCGGTACTGCAGACGACCACTAGCTTACGGGATGTCTTATTTCGTCGCATGAAGAAGGTGCCCGCGCTGCAAG
GGCAGGTGGTCACAAATATGTTTTTTGAGCCATCGACCCGTACCCGGAGTAGTTTTGAGTTGGCGGCGAAACGGCTTTCG
GCGGATGTAATGAATTTTGCGCCGGGATCTTCGTCCCTGAGTAAGGGGGAAACGATTTTGGATACAGCGAAGACTTATCT
GGCCATGGGGGCAGACATTATGGTGATTCGCCACCAGCAATCGGGTGTTCCCCAGGCGATCGCCGCCGAGATGGATCGGA
TAAATTCAGGCGTCAGTATTCTCAATGCGGGGGATGGCCTCCACGCCCACCCGTCCCAAGCCCTATTGGATCTGTTTACC
ATTTGCCGGGTACTCGATCCCGAAAATCCCCGGTGTGAACTTTTGCGGGGCAAAAAAATTGCCATTGTCGGGGATATTAT
GCACTCTCGGGTGGCCCGCTCGAATATTTGGAGTTTGACCACCGCTGGGGCCGATGTCCACTTAGCCGCGCCGCCCACTT
TGCTCCCAGAAGGATTTCGGGAATTTGCCACGGACGCCGCGGGAAGCCTCAAGCTCCACTGGGACATTGAACCTGCTCTC
AAAGACGCCGATTTTGTGATGACCCTCCGCCTGCAACATGAGCGGATGACCGCCCATCTCCTCCCCAGTTTGCGGGAATA
TCATCAACGGTTTGGCATTACAGGCGATCGCCTTAAATTTTGTCAACCAGATGTTAAAGTGCTCCATCCGGGGCCTGTGA
ATCGTGGCGTGGAACTTGCCTCCGATGTGATGGATCATCCCGCCCTCAGTCTTGTTTCTGAGCAGGTGACCAATGGCGTC
GCTGTACGGATGGCGTTGCTTTATCTCATCGGTAGCAGTAAGGCCAATGGTTCTCTCAATTAA

Upstream 100 bases:

>100_bases
GCTTTTTCCACACGGATGCTGCGTAAGGACACCTAATTTGATTGGTTAAGATGGGGAGGGCGTCACAGAAAGTGCCCTCT
TTTTTGTGGCTTGATAGTGA

Downstream 100 bases:

>100_bases
GCATTGGCGCAATAACCTATAGCAAAGTTGTGGTCAGACTCGGCTGCATTTTACTCAACCAATAAAACTGGAACGGTGCC
AGCACAAGTTGTTTTTCAAA

Product: aspartate carbamoyltransferase catalytic subunit

Products: NA

Alternate protein names: Aspartate transcarbamylase; ATCase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGTVMTTATATWTRRHILSLMDFSVAELDAVLQTTTSLRDVLFRRMKKVPALQGQVVTNMFFEPSTRTRSSFELAAKRLS
ADVMNFAPGSSSLSKGETILDTAKTYLAMGADIMVIRHQQSGVPQAIAAEMDRINSGVSILNAGDGLHAHPSQALLDLFT
ICRVLDPENPRCELLRGKKIAIVGDIMHSRVARSNIWSLTTAGADVHLAAPPTLLPEGFREFATDAAGSLKLHWDIEPAL
KDADFVMTLRLQHERMTAHLLPSLREYHQRFGITGDRLKFCQPDVKVLHPGPVNRGVELASDVMDHPALSLVSEQVTNGV
AVRMALLYLIGSSKANGSLN

Sequences:

>Translated_340_residues
MGTVMTTATATWTRRHILSLMDFSVAELDAVLQTTTSLRDVLFRRMKKVPALQGQVVTNMFFEPSTRTRSSFELAAKRLS
ADVMNFAPGSSSLSKGETILDTAKTYLAMGADIMVIRHQQSGVPQAIAAEMDRINSGVSILNAGDGLHAHPSQALLDLFT
ICRVLDPENPRCELLRGKKIAIVGDIMHSRVARSNIWSLTTAGADVHLAAPPTLLPEGFREFATDAAGSLKLHWDIEPAL
KDADFVMTLRLQHERMTAHLLPSLREYHQRFGITGDRLKFCQPDVKVLHPGPVNRGVELASDVMDHPALSLVSEQVTNGV
AVRMALLYLIGSSKANGSLN
>Mature_339_residues
GTVMTTATATWTRRHILSLMDFSVAELDAVLQTTTSLRDVLFRRMKKVPALQGQVVTNMFFEPSTRTRSSFELAAKRLSA
DVMNFAPGSSSLSKGETILDTAKTYLAMGADIMVIRHQQSGVPQAIAAEMDRINSGVSILNAGDGLHAHPSQALLDLFTI
CRVLDPENPRCELLRGKKIAIVGDIMHSRVARSNIWSLTTAGADVHLAAPPTLLPEGFREFATDAAGSLKLHWDIEPALK
DADFVMTLRLQHERMTAHLLPSLREYHQRFGITGDRLKFCQPDVKVLHPGPVNRGVELASDVMDHPALSLVSEQVTNGVA
VRMALLYLIGSSKANGSLN

Specific function: Pyrimidine biosynthesis; second step. [C]

COG id: COG0540

COG function: function code F; Aspartate carbamoyltransferase, catalytic chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=317, Percent_Identity=33.7539432176656, Blast_Score=151, Evalue=7e-37,
Organism=Escherichia coli, GI2367364, Length=321, Percent_Identity=32.398753894081, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=28.1437125748503, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786469, Length=348, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193204318, Length=301, Percent_Identity=31.5614617940199, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322331, Length=323, Percent_Identity=34.0557275541796, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24642586, Length=323, Percent_Identity=29.7213622291022, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: 2080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 14328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002082 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.2 [H]

Molecular weight: Translated: 37160; Mature: 37029

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVMTTATATWTRRHILSLMDFSVAELDAVLQTTTSLRDVLFRRMKKVPALQGQVVTNM
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FFEPSTRTRSSFELAAKRLSADVMNFAPGSSSLSKGETILDTAKTYLAMGADIMVIRHQQ
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
SGVPQAIAAEMDRINSGVSILNAGDGLHAHPSQALLDLFTICRVLDPENPRCELLRGKKI
CCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCEE
AIVGDIMHSRVARSNIWSLTTAGADVHLAAPPTLLPEGFREFATDAAGSLKLHWDIEPAL
EEEHHHHHHHHHHHCCCEEEECCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCHHH
KDADFVMTLRLQHERMTAHLLPSLREYHQRFGITGDRLKFCQPDVKVLHPGPVNRGVELA
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEECCCCCCCHHHHH
SDVMDHPALSLVSEQVTNGVAVRMALLYLIGSSKANGSLN
HHHHCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GTVMTTATATWTRRHILSLMDFSVAELDAVLQTTTSLRDVLFRRMKKVPALQGQVVTNM
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FFEPSTRTRSSFELAAKRLSADVMNFAPGSSSLSKGETILDTAKTYLAMGADIMVIRHQQ
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
SGVPQAIAAEMDRINSGVSILNAGDGLHAHPSQALLDLFTICRVLDPENPRCELLRGKKI
CCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCEE
AIVGDIMHSRVARSNIWSLTTAGADVHLAAPPTLLPEGFREFATDAAGSLKLHWDIEPAL
EEEHHHHHHHHHHHCCCEEEECCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCHHH
KDADFVMTLRLQHERMTAHLLPSLREYHQRFGITGDRLKFCQPDVKVLHPGPVNRGVELA
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEECCCCCCCHHHHH
SDVMDHPALSLVSEQVTNGVAVRMALLYLIGSSKANGSLN
HHHHCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA