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The map label for this gene is ahpC [C]

Identifier: 170077183

GI number: 170077183

Start: 584787

End: 585374

Strand: Reverse

Name: ahpC [C]

Synonym: SYNPCC7002_A0558

Alternate gene names: 170077183

Gene position: 585374-584787 (Counterclockwise)

Preceding gene: 170077184

Following gene: 170077182

Centisome position: 19.46

GC content: 51.36

Gene sequence:

>588_bases
ATGGCCGCACAAGTGGGACAATTGGCACCGGACTTTACCGCTACCGCCGTCATTGATCAAGAGTTCAAAACCATTAAGTT
GTCCGACTATCGGGGGCAATATGTGGTGTTGTTTTTCTACCCGCTCGATTTCACTTTTGTCTGTCCAACAGAAGTAGGAG
CCTTTAGCGATCGCCACGGGGAATTTCAAAAACTCAATACGGAAGTATTGGGCGTTTCCGTAGATAGTGAATTTGCGCAC
CTCGCCTGGATCCAAACAGACCGCAAAATGGGTGGCGTGGGCGATTTAGCCTTTCCCCTGGTGTCTGATTTAAACAAAAC
CATTAGCACGGCCTACGGCGTCCTCGAACCGGAAGCGGGGATCTCCCTGCGGGGACTTTTTATCATCGACCCGGAAGGAA
TGATCCAACACATCACCGTGAATAATTTTTCCTTTGGCCGCAGCCTTGACGAAACCCTGCGGGTGCTCCAAGCGATTCAG
CACGTCCAGACTAATCACAATGAAGTTTGTCCCGTCGATTGGCAAGTGGGCGATCGCACCATGGTGCCAAACCCAAGCGA
AGCCCAGGCTTATTTCTCGACCCTCTAG

Upstream 100 bases:

>100_bases
AAGGCCCAGGGCGTTTTGTAACCCATTTTCACTGGTTTTCGGGACGCAAAATAGCGGTGTGATACCTTGGGGAAAGATTT
TGCGTTGGAACACGATAACC

Downstream 100 bases:

>100_bases
GGAAAAACTGCCGGATTGACCGCAAGAAAGGCTAAAGTGTGAAGGCACTTTGAAAGCGAATTTAGCACCATGCACCAAGG
CGATCTGATTGAACTCTCCA

Product: Alkyl hydroperoxide reductase; peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MAAQVGQLAPDFTATAVIDQEFKTIKLSDYRGQYVVLFFYPLDFTFVCPTEVGAFSDRHGEFQKLNTEVLGVSVDSEFAH
LAWIQTDRKMGGVGDLAFPLVSDLNKTISTAYGVLEPEAGISLRGLFIIDPEGMIQHITVNNFSFGRSLDETLRVLQAIQ
HVQTNHNEVCPVDWQVGDRTMVPNPSEAQAYFSTL

Sequences:

>Translated_195_residues
MAAQVGQLAPDFTATAVIDQEFKTIKLSDYRGQYVVLFFYPLDFTFVCPTEVGAFSDRHGEFQKLNTEVLGVSVDSEFAH
LAWIQTDRKMGGVGDLAFPLVSDLNKTISTAYGVLEPEAGISLRGLFIIDPEGMIQHITVNNFSFGRSLDETLRVLQAIQ
HVQTNHNEVCPVDWQVGDRTMVPNPSEAQAYFSTL
>Mature_194_residues
AAQVGQLAPDFTATAVIDQEFKTIKLSDYRGQYVVLFFYPLDFTFVCPTEVGAFSDRHGEFQKLNTEVLGVSVDSEFAHL
AWIQTDRKMGGVGDLAFPLVSDLNKTISTAYGVLEPEAGISLRGLFIIDPEGMIQHITVNNFSFGRSLDETLRVLQAIQH
VQTNHNEVCPVDWQVGDRTMVPNPSEAQAYFSTL

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=191, Percent_Identity=58.1151832460733, Blast_Score=238, Evalue=2e-63,
Organism=Homo sapiens, GI4505591, Length=192, Percent_Identity=57.2916666666667, Blast_Score=232, Evalue=2e-61,
Organism=Homo sapiens, GI32455266, Length=192, Percent_Identity=57.2916666666667, Blast_Score=232, Evalue=2e-61,
Organism=Homo sapiens, GI32455264, Length=192, Percent_Identity=57.2916666666667, Blast_Score=232, Evalue=2e-61,
Organism=Homo sapiens, GI5802974, Length=191, Percent_Identity=55.4973821989529, Blast_Score=228, Evalue=2e-60,
Organism=Homo sapiens, GI5453549, Length=193, Percent_Identity=54.4041450777202, Blast_Score=226, Evalue=1e-59,
Organism=Homo sapiens, GI32483377, Length=184, Percent_Identity=55.9782608695652, Blast_Score=225, Evalue=2e-59,
Organism=Homo sapiens, GI33188454, Length=87, Percent_Identity=67.816091954023, Blast_Score=130, Evalue=6e-31,
Organism=Homo sapiens, GI4758638, Length=197, Percent_Identity=31.9796954314721, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1786822, Length=173, Percent_Identity=35.2601156069364, Blast_Score=131, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI193204376, Length=191, Percent_Identity=54.9738219895288, Blast_Score=221, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=54.9738219895288, Blast_Score=220, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17554494, Length=186, Percent_Identity=51.6129032258064, Blast_Score=216, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI25153706, Length=197, Percent_Identity=28.9340101522843, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323613, Length=192, Percent_Identity=47.3958333333333, Blast_Score=188, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6320661, Length=194, Percent_Identity=46.3917525773196, Blast_Score=185, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319407, Length=202, Percent_Identity=32.6732673267327, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17738015, Length=194, Percent_Identity=56.1855670103093, Blast_Score=229, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24656348, Length=191, Percent_Identity=56.5445026178011, Blast_Score=227, Evalue=4e-60,
Organism=Drosophila melanogaster, GI17864676, Length=191, Percent_Identity=56.5445026178011, Blast_Score=227, Evalue=4e-60,
Organism=Drosophila melanogaster, GI17157991, Length=191, Percent_Identity=53.4031413612565, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24641739, Length=191, Percent_Identity=53.4031413612565, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI21357347, Length=190, Percent_Identity=48.9473684210526, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17975518, Length=198, Percent_Identity=31.3131313131313, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24652434, Length=198, Percent_Identity=31.3131313131313, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24652436, Length=198, Percent_Identity=31.3131313131313, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581278, Length=188, Percent_Identity=28.1914893617021, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21651; Mature: 21519

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQVGQLAPDFTATAVIDQEFKTIKLSDYRGQYVVLFFYPLDFTFVCPTEVGAFSDRHG
CCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEECCEEEECCCCCCCCCCCCC
EFQKLNTEVLGVSVDSEFAHLAWIQTDRKMGGVGDLAFPLVSDLNKTISTAYGVLEPEAG
CHHHCCEEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
ISLRGLFIIDPEGMIQHITVNNFSFGRSLDETLRVLQAIQHVQTNHNEVCPVDWQVGDRT
CEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
MVPNPSEAQAYFSTL
ECCCCCHHHHHHHCC
>Mature Secondary Structure 
AAQVGQLAPDFTATAVIDQEFKTIKLSDYRGQYVVLFFYPLDFTFVCPTEVGAFSDRHG
CCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEECCEEEECCCCCCCCCCCCC
EFQKLNTEVLGVSVDSEFAHLAWIQTDRKMGGVGDLAFPLVSDLNKTISTAYGVLEPEAG
CHHHCCEEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
ISLRGLFIIDPEGMIQHITVNNFSFGRSLDETLRVLQAIQHVQTNHNEVCPVDWQVGDRT
CEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
MVPNPSEAQAYFSTL
ECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]