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The map label for this gene is rumA [C]

Identifier: 170077182

GI number: 170077182

Start: 583359

End: 584717

Strand: Reverse

Name: rumA [C]

Synonym: SYNPCC7002_A0557

Alternate gene names: 170077182

Gene position: 584717-583359 (Counterclockwise)

Preceding gene: 170077183

Following gene: 170077181

Centisome position: 19.44

GC content: 52.98

Gene sequence:

>1359_bases
ATGCACCAAGGCGATCTGATTGAACTCTCCATCCATGACCTTAATAGCCAGGGGGCTGGGGTCGGTCGCCATGGGGATCA
AGTTGTGTTTGTGCCGGATACGGTGCCAGGCGATCGCCTCCAGGTGCGGATCGTCCGTCTCAAGCGACAATACGCCATCG
GTCAACTGCAAAAAGTTTTAGAACCCGCCCCAGAACGGCGGCGTCCCCCCTGCATCGTGGCGGACAAATGCGGTGGTTGT
CAGTGGCTCCAGGTAGAAGATTCTCTACAACAGCAGGTCAAAACCAACGAAATTCAACAGGCCCTCCAGCGCATTGGTGG
TTTCCAGGATCTCGACATTCAGCCGATCCTGAGTGGTGATGGGCCATTGAGTTATCGCAATAAGGCCACCTATCCCCTGG
GTCGTTCCAGTAGTATGGGCAATGTGCAAGCCGGGTATTACCGCAAAGGAAGCCACCAACTGATCAACCTCAACCAATGC
CCAGTACAGGATTCGCGCCTCAATCCCCTCTTGGAAAATGTCAAAATTGACATCCAAAACCAAGGCTGGTCGATCTACAA
CGAAACCAAACACCAGGGCAAATTACGCCACCTCGCCCTCCGCATTGGTCAGCGCACCGGGGAAATGCTGTTGACGCTAA
TTTCCACCAGTGGTGATTTGATTAACCTAGAAACCCAAGCTGAAACCTGGCTCGAAGAATATCCCGGTCTTGTGGGGGTT
TGTTTGAACGAAAACCCGAAAAAAGGCAACCTCATCTGGGGTGACACCACAAAGGCGATCGCCGGTCGTCCCTACCTCGA
AGAAATTTTTGCGGGACTAACCCTCAAGCTCCGGCCTGAAACCTTTTTCCAAGTCAACACCAGCGCCGCCGAAGCCCTCC
TTACGGCAATTACTCAACAGCTCACCTTTACCGGTGAAGAAATCCTCGTCGATGCCTACTGTGGTGTGGGAACCTTCACC
TTGCCCCTAGCGAAAAAAGTCCAGCAGGCGATCGGCATCGAAGTTCAAGCAAGCTCGATCCAGCAGGCCTGGGAAAATGC
CCACCACAACGATATCCATAATGTGGAATTCTACGCTGGCACCGTAGAGTCAATTCTACCTAGTCTGGATGTCACTGCTG
ATATCGTGCTCCTTGATCCCCCCCGTAAAGGCTGCGATCGCCAAGTGCTCGATGCTCTCCTTCACAGCAAACCCAAGCAA
ATTGTTTATATCAGTTGTAATCCTGCAACCCTCGCCCGCGACCTCAAACACCTTTGTGCCACCCAACAGTACCAAATCCA
GTGGGTGCAGCCCGCCGACTTCTTTCCCCAAACGCCCCATGTCGAATGCGCCGTTCTCTTGAATTTCGTGGAAACCTAA

Upstream 100 bases:

>100_bases
CGAAGCCCAGGCTTATTTCTCGACCCTCTAGGGAAAAACTGCCGGATTGACCGCAAGAAAGGCTAAAGTGTGAAGGCACT
TTGAAAGCGAATTTAGCACC

Downstream 100 bases:

>100_bases
AATTTTTTGTATAATACAAGGCAGAAACCACGACAAGATCGTTCGGGATTCCCTACAGGCAAACAAACTATGTTGTGACC
ACTACTTTTTGGGTTTATGC

Product: 23S rRNA (uracil-5-)-methyltransferase RumA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MHQGDLIELSIHDLNSQGAGVGRHGDQVVFVPDTVPGDRLQVRIVRLKRQYAIGQLQKVLEPAPERRRPPCIVADKCGGC
QWLQVEDSLQQQVKTNEIQQALQRIGGFQDLDIQPILSGDGPLSYRNKATYPLGRSSSMGNVQAGYYRKGSHQLINLNQC
PVQDSRLNPLLENVKIDIQNQGWSIYNETKHQGKLRHLALRIGQRTGEMLLTLISTSGDLINLETQAETWLEEYPGLVGV
CLNENPKKGNLIWGDTTKAIAGRPYLEEIFAGLTLKLRPETFFQVNTSAAEALLTAITQQLTFTGEEILVDAYCGVGTFT
LPLAKKVQQAIGIEVQASSIQQAWENAHHNDIHNVEFYAGTVESILPSLDVTADIVLLDPPRKGCDRQVLDALLHSKPKQ
IVYISCNPATLARDLKHLCATQQYQIQWVQPADFFPQTPHVECAVLLNFVET

Sequences:

>Translated_452_residues
MHQGDLIELSIHDLNSQGAGVGRHGDQVVFVPDTVPGDRLQVRIVRLKRQYAIGQLQKVLEPAPERRRPPCIVADKCGGC
QWLQVEDSLQQQVKTNEIQQALQRIGGFQDLDIQPILSGDGPLSYRNKATYPLGRSSSMGNVQAGYYRKGSHQLINLNQC
PVQDSRLNPLLENVKIDIQNQGWSIYNETKHQGKLRHLALRIGQRTGEMLLTLISTSGDLINLETQAETWLEEYPGLVGV
CLNENPKKGNLIWGDTTKAIAGRPYLEEIFAGLTLKLRPETFFQVNTSAAEALLTAITQQLTFTGEEILVDAYCGVGTFT
LPLAKKVQQAIGIEVQASSIQQAWENAHHNDIHNVEFYAGTVESILPSLDVTADIVLLDPPRKGCDRQVLDALLHSKPKQ
IVYISCNPATLARDLKHLCATQQYQIQWVQPADFFPQTPHVECAVLLNFVET
>Mature_452_residues
MHQGDLIELSIHDLNSQGAGVGRHGDQVVFVPDTVPGDRLQVRIVRLKRQYAIGQLQKVLEPAPERRRPPCIVADKCGGC
QWLQVEDSLQQQVKTNEIQQALQRIGGFQDLDIQPILSGDGPLSYRNKATYPLGRSSSMGNVQAGYYRKGSHQLINLNQC
PVQDSRLNPLLENVKIDIQNQGWSIYNETKHQGKLRHLALRIGQRTGEMLLTLISTSGDLINLETQAETWLEEYPGLVGV
CLNENPKKGNLIWGDTTKAIAGRPYLEEIFAGLTLKLRPETFFQVNTSAAEALLTAITQQLTFTGEEILVDAYCGVGTFT
LPLAKKVQQAIGIEVQASSIQQAWENAHHNDIHNVEFYAGTVESILPSLDVTADIVLLDPPRKGCDRQVLDALLHSKPKQ
IVYISCNPATLARDLKHLCATQQYQIQWVQPADFFPQTPHVECAVLLNFVET

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=295, Percent_Identity=30.5084745762712, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI51173878, Length=295, Percent_Identity=30.5084745762712, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI269784678, Length=367, Percent_Identity=24.7956403269755, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI269784680, Length=367, Percent_Identity=24.7956403269755, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI269784676, Length=367, Percent_Identity=24.7956403269755, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI20149688, Length=367, Percent_Identity=24.7956403269755, Blast_Score=106, Evalue=5e-23,
Organism=Escherichia coli, GI1789148, Length=462, Percent_Identity=29.4372294372294, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787083, Length=381, Percent_Identity=27.8215223097113, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790403, Length=154, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322909, Length=450, Percent_Identity=25.1111111111111, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24666579, Length=388, Percent_Identity=24.7422680412371, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 50276; Mature: 50276

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQGDLIELSIHDLNSQGAGVGRHGDQVVFVPDTVPGDRLQVRIVRLKRQYAIGQLQKVL
CCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHH
EPAPERRRPPCIVADKCGGCQWLQVEDSLQQQVKTNEIQQALQRIGGFQDLDIQPILSGD
CCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GPLSYRNKATYPLGRSSSMGNVQAGYYRKGSHQLINLNQCPVQDSRLNPLLENVKIDIQN
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCCCCCCCCHHHHCCEEEEEC
QGWSIYNETKHQGKLRHLALRIGQRTGEMLLTLISTSGDLINLETQAETWLEEYPGLVGV
CCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCEEEEEHHHHHHHHHCCCEEEE
CLNENPKKGNLIWGDTTKAIAGRPYLEEIFAGLTLKLRPETFFQVNTSAAEALLTAITQQ
EECCCCCCCCEEECCCCHHHCCCCHHHHHHCCCEEEECCCEEEEECCHHHHHHHHHHHHH
LTFTGEEILVDAYCGVGTFTLPLAKKVQQAIGIEVQASSIQQAWENAHHNDIHNVEFYAG
HHCCCCEEEEEECCCCCEEHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCCCEEEECC
TVESILPSLDVTADIVLLDPPRKGCDRQVLDALLHSKPKQIVYISCNPATLARDLKHLCA
CHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHC
TQQYQIQWVQPADFFPQTPHVECAVLLNFVET
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MHQGDLIELSIHDLNSQGAGVGRHGDQVVFVPDTVPGDRLQVRIVRLKRQYAIGQLQKVL
CCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHH
EPAPERRRPPCIVADKCGGCQWLQVEDSLQQQVKTNEIQQALQRIGGFQDLDIQPILSGD
CCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GPLSYRNKATYPLGRSSSMGNVQAGYYRKGSHQLINLNQCPVQDSRLNPLLENVKIDIQN
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCCCCCCCCHHHHCCEEEEEC
QGWSIYNETKHQGKLRHLALRIGQRTGEMLLTLISTSGDLINLETQAETWLEEYPGLVGV
CCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCEEEEEHHHHHHHHHCCCEEEE
CLNENPKKGNLIWGDTTKAIAGRPYLEEIFAGLTLKLRPETFFQVNTSAAEALLTAITQQ
EECCCCCCCCEEECCCCHHHCCCCHHHHHHCCCEEEECCCEEEEECCHHHHHHHHHHHHH
LTFTGEEILVDAYCGVGTFTLPLAKKVQQAIGIEVQASSIQQAWENAHHNDIHNVEFYAG
HHCCCCEEEEEECCCCCEEHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCCCEEEECC
TVESILPSLDVTADIVLLDPPRKGCDRQVLDALLHSKPKQIVYISCNPATLARDLKHLCA
CHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHC
TQQYQIQWVQPADFFPQTPHVECAVLLNFVET
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]