Click here to switch to the map view.

The map label for this gene is ispH

Identifier: 170077142

GI number: 170077142

Start: 546910

End: 548121

Strand: Direct

Name: ispH

Synonym: SYNPCC7002_A0517

Alternate gene names: 170077142

Gene position: 546910-548121 (Clockwise)

Preceding gene: 170077141

Following gene: 170077144

Centisome position: 18.18

GC content: 47.69

Gene sequence:

>1212_bases
ATGGATACCAAAGCCTTTAAACGTTCCCTAAATCACTCTGAAAATTACTATCGCCAAGGATTTGGCCATAAAGATGAAGT
GGCTGGCATGATGACCAGCGAATATCAAAGTAGCCTGATCCAAGAGATCCGTGACAACAACTATGAGTTAACCCGTGGTG
ATGTCACCATTTACCTGGCGGAGGCGTTTGGCTTTTGTTGGGGGGTAGAACGGGCAGTGGCGATGGCCTACGAAACCCGC
AAGCATTTCCCTACGGAAAAAATCTGGGTAACAAACGAAATTATCCACAATCCCTCGGTGAATAATCGTCTGAAGGAGAT
GAATGTTCATTTTATTGAGGTGGTTGATGGCGATAAGGATTTTAGTGGTGTGGCGAATGGCGATGTGGTGATTCTGCCTG
CCTTTGGGGCGACGGTGCAAGAAATGCAACTGCTCAATGATCGCGGTTGCACGATTGTGGATACCACCTGCCCTTGGGTT
TCTAAGGTGTGGAATTCCGTTGAAAAGCATAAAAAGAAAAATTACACTTCGATTATCCACGGCAAATATAAGCATGAGGA
AACGGTGGCTACCAGTTCCTTTGCGGGGACCTATCTAGTGCTCCTGAATCTAGAAGAAGCGGAATATGTCCGGAATTACA
TTCTCCATGGAGGCGATCGCCAAACGTTCCTCGATAAGTTTAAAAATGCCTATTCCGAAGGGTTCGACCCTGACAAAGAT
CTAGACCGTGTGGGTGTGGCGAATCAAACCACCATGCTTAAGAGCGAAACGGAACAAATGGGCAAACTGTTTGAACAGAC
GATGCTCGAAAAATTTGGCCCGACGGAAATTAATGACCACTTCATGAGCTTCAATACGATTTGTGATGCCACCCAAGAGC
GGCAGGATGCGATGTTTGACCTCGTGGAAAAAGATTTAGATCTGATGGTCGTCATCGGTGGCTTCAATTCCTCCAATACC
ACCCACCTCCAGGAAATCGCCGTCGAGCGCAATATTCCTTCCTATCACATCGACAGCGGCGATCGCCTTTTAGGGAATAA
CGTTATTGCCCACAAACCCCTCGATGGTGAAATCACGACCCAAACCCACTGGCTCCCGGCTGGCAAACTAAAAATTGGTG
TGACCTCCGGCGCGTCTACCCCCGACAAAGTTGTTGAAGACGTCATTGCGAAAATCTTTGCCGAAAAAGCCCAACCAGCG
GCCTTGGTCTAA

Upstream 100 bases:

>100_bases
ACGAAACCTCCAAAACCGAAGATACTCCCAAAGATTAGGGATCGCCCCAAGAATTCGCTATGATCTTTGACTGAAGCGTA
TCGTTGATCTCCCGTGCCCT

Downstream 100 bases:

>100_bases
CTTCTTCAGGCACCGTTAAACATTCGCAAACGTAAAAAATCTTTACCCCGTCCTAATGCTGGCGATCGCCTGGGGATGGG
GATTTTTTTATTGGGGAAAT

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MDTKAFKRSLNHSENYYRQGFGHKDEVAGMMTSEYQSSLIQEIRDNNYELTRGDVTIYLAEAFGFCWGVERAVAMAYETR
KHFPTEKIWVTNEIIHNPSVNNRLKEMNVHFIEVVDGDKDFSGVANGDVVILPAFGATVQEMQLLNDRGCTIVDTTCPWV
SKVWNSVEKHKKKNYTSIIHGKYKHEETVATSSFAGTYLVLLNLEEAEYVRNYILHGGDRQTFLDKFKNAYSEGFDPDKD
LDRVGVANQTTMLKSETEQMGKLFEQTMLEKFGPTEINDHFMSFNTICDATQERQDAMFDLVEKDLDLMVVIGGFNSSNT
THLQEIAVERNIPSYHIDSGDRLLGNNVIAHKPLDGEITTQTHWLPAGKLKIGVTSGASTPDKVVEDVIAKIFAEKAQPA
ALV

Sequences:

>Translated_403_residues
MDTKAFKRSLNHSENYYRQGFGHKDEVAGMMTSEYQSSLIQEIRDNNYELTRGDVTIYLAEAFGFCWGVERAVAMAYETR
KHFPTEKIWVTNEIIHNPSVNNRLKEMNVHFIEVVDGDKDFSGVANGDVVILPAFGATVQEMQLLNDRGCTIVDTTCPWV
SKVWNSVEKHKKKNYTSIIHGKYKHEETVATSSFAGTYLVLLNLEEAEYVRNYILHGGDRQTFLDKFKNAYSEGFDPDKD
LDRVGVANQTTMLKSETEQMGKLFEQTMLEKFGPTEINDHFMSFNTICDATQERQDAMFDLVEKDLDLMVVIGGFNSSNT
THLQEIAVERNIPSYHIDSGDRLLGNNVIAHKPLDGEITTQTHWLPAGKLKIGVTSGASTPDKVVEDVIAKIFAEKAQPA
ALV
>Mature_403_residues
MDTKAFKRSLNHSENYYRQGFGHKDEVAGMMTSEYQSSLIQEIRDNNYELTRGDVTIYLAEAFGFCWGVERAVAMAYETR
KHFPTEKIWVTNEIIHNPSVNNRLKEMNVHFIEVVDGDKDFSGVANGDVVILPAFGATVQEMQLLNDRGCTIVDTTCPWV
SKVWNSVEKHKKKNYTSIIHGKYKHEETVATSSFAGTYLVLLNLEEAEYVRNYILHGGDRQTFLDKFKNAYSEGFDPDKD
LDRVGVANQTTMLKSETEQMGKLFEQTMLEKFGPTEINDHFMSFNTICDATQERQDAMFDLVEKDLDLMVVIGGFNSSNT
THLQEIAVERNIPSYHIDSGDRLLGNNVIAHKPLDGEITTQTHWLPAGKLKIGVTSGASTPDKVVEDVIAKIFAEKAQPA
ALV

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family

Homologues:

Organism=Escherichia coli, GI1786212, Length=341, Percent_Identity=26.6862170087977, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPH_SYNP2 (B1XPG7)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001733780.1
- GeneID:   6055826
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0517
- HOGENOM:   HBG286221
- OMA:   HMQVARA
- ProtClustDB:   PRK13371
- HAMAP:   MF_00191
- InterPro:   IPR003451
- TIGRFAMs:   TIGR00216

Pfam domain/function: PF02401 LYTB

EC number: =1.17.1.2

Molecular weight: Translated: 45455; Mature: 45455

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKAFKRSLNHSENYYRQGFGHKDEVAGMMTSEYQSSLIQEIRDNNYELTRGDVTIYLA
CCHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEHH
EAFGFCWGVERAVAMAYETRKHFPTEKIWVTNEIIHNPSVNNRLKEMNVHFIEVVDGDKD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHCCEEEEEEECCCCC
FSGVANGDVVILPAFGATVQEMQLLNDRGCTIVDTTCPWVSKVWNSVEKHKKKNYTSIIH
CCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHC
GKYKHEETVATSSFAGTYLVLLNLEEAEYVRNYILHGGDRQTFLDKFKNAYSEGFDPDKD
CCCCCHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
LDRVGVANQTTMLKSETEQMGKLFEQTMLEKFGPTEINDHFMSFNTICDATQERQDAMFD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVEKDLDLMVVIGGFNSSNTTHLQEIAVERNIPSYHIDSGDRLLGNNVIAHKPLDGEITT
HHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCEEEECCCCCCEEC
QTHWLPAGKLKIGVTSGASTPDKVVEDVIAKIFAEKAQPAALV
CEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTKAFKRSLNHSENYYRQGFGHKDEVAGMMTSEYQSSLIQEIRDNNYELTRGDVTIYLA
CCHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEHH
EAFGFCWGVERAVAMAYETRKHFPTEKIWVTNEIIHNPSVNNRLKEMNVHFIEVVDGDKD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHCCEEEEEEECCCCC
FSGVANGDVVILPAFGATVQEMQLLNDRGCTIVDTTCPWVSKVWNSVEKHKKKNYTSIIH
CCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHC
GKYKHEETVATSSFAGTYLVLLNLEEAEYVRNYILHGGDRQTFLDKFKNAYSEGFDPDKD
CCCCCHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
LDRVGVANQTTMLKSETEQMGKLFEQTMLEKFGPTEINDHFMSFNTICDATQERQDAMFD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVEKDLDLMVVIGGFNSSNTTHLQEIAVERNIPSYHIDSGDRLLGNNVIAHKPLDGEITT
HHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCEEEECCCCCCEEC
QTHWLPAGKLKIGVTSGASTPDKVVEDVIAKIFAEKAQPAALV
CEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA