Click here to switch to the map view.

The map label for this gene is dnaK [H]

Identifier: 170077102

GI number: 170077102

Start: 505783

End: 507387

Strand: Direct

Name: dnaK [H]

Synonym: SYNPCC7002_A0476

Alternate gene names: 170077102

Gene position: 505783-507387 (Clockwise)

Preceding gene: 170077100

Following gene: 170077103

Centisome position: 16.81

GC content: 51.28

Gene sequence:

>1605_bases
ATGGCGATCGCAGTGGATTTTGGGACGAGCAATACCCTAGTGACCCGGTGGAATGCCGCCAAAGGAGCCCCAGAAATTCT
CCCACTCCAGGGTCTTTCCCAACGCATTTCCCCGAATCCACCGCTGATCCCCAGCCTTTTGTACATCGAAAATGCCGCCG
ACCAAAAAGTCGTTATCGGTCAAGCCATTGGCGATCGCGGTTTAGATCGCGGCCCCGATCCCCGCTATTTCTGTAACTTT
AAACGGGGCATTGGCACCGCAATCCAAGGTTTTTTACCGGAACTAGACGGCGAAAAAATCACCTTTGAAAAAATGGGGGA
ATATTTCCTCAACGGCATTTTTGCCCAACTCAAAGCCCAGGGTGAACCCCTCGATAGCCTCGTTTTAACCGTGCCAGTCG
ATAGTTTTGAAGCCTACCGGAGTTGGCTGAGTCGGCTTTGTGAGCAGTTGCCAGAACTCGAAAAAATTCAGCTTTTGGAC
GAACCCACCGCCGCCGCCTTGGGCTATGGAGCCTTGGCTGAAGATTTAAAAAGAGTTCTCGTGGTGGATTTTGGGGGGGG
AACCGTAGATTTTTCTCTCGTAGATCTCAACCTGGCCCAGGGCCAAAGCAAACCGACGGGCTTTATTTTGAAGTGGGGGC
GTAAATCCTTTGCCGAAAGCAAAACCCAAAAAGTCAAAACCGCAAAAGTGCTGGCGAAAGCAGGTAAAAATCTCGGTGGT
TCTGATTTAGATAATTGGCTCTTTGAATATTTCCAGACCCAACAAAATTTGCCCCAGGATGCCCTGAGTTTACGCTTAGT
TGAACGGTTGAAAATTGCCCTCTCCCAAAAGACGAAGGCAACGGAGATTTATTACAACGACCAAACCTTTGAAACCTATG
AGTTGACCCTGGGTCGGTCGGCCTTTGAGGAGATTTTAGAAAATCAAGGCTTCCTCGCCCAACTTGATGATTTGCTGGCC
CAGGTCTTGCAACAGGCCCGCCGTAATGGTGTCGGCAAAGAGGATATCGAAGCGGTGCTCCTAGTCGGAGGCACGAGCCA
AATTCCCCTAGTGCAAAGCTGGTTAGAGGGCTATTTCCCCCCGGAAAAAATTAAACGAGATAATCCCTTTGGGGCGATCG
CCTGGGGGGCGTTGCAGTTGGCCCAGGGATTTGAACTCAAAGATTTTCTTTACCACAGCTACGGTATCCGCTACTGGAAT
CGCCGCCATAATCGCCACGATTGGCAACCGATTATTAACCAAGGCCAGCCCTACCCGATGACGGAACCGCTGGAAATCAC
CCTAGGGGCATCGATGGATCAACAGCCCAGCATTGAACTAATCGTTGGCGAGTTGGGAGAACAAAGCAGCGGCACGGAGG
TTTATTTCGATGGCGATCGCCTCGTGACCCAACAACTAGGAGCCAACCAAACCAACGTTAAACCCCTCAATGACCGGGAA
GGGGCGCGCACCATTGCCAAACTGGATCCCGTGGGCTATCCCGGCACTGACCGCATTAAGTTGCAATTCCTCGTCGATGG
CGATCGCACCTTGCGGGTTACCGTCGAGGATCTACTGCGCAATGTCACCCTCATTGAAAACCAAAAAGTTGCCGAGTTGA
GTTAG

Upstream 100 bases:

>100_bases
TGCTTTCGGGAATGATTGGGCCAGGGCGACCGGAAACCGTCGAACTCGATACAATACAAAAATTGTCCAGTTTAGCTTTC
AAGAAAATCACGAAATCATT

Downstream 100 bases:

>100_bases
CTGCCCATCCCCAGGACAGCCCTGCTAAAATCCATAGAAGCCCTTCAATCTCACAAAATCGATGAAAAATCCCCAACTCA
AGAAGATGCGTCTCCTGGTC

Product: DnaK-type molecular chaperone

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MAIAVDFGTSNTLVTRWNAAKGAPEILPLQGLSQRISPNPPLIPSLLYIENAADQKVVIGQAIGDRGLDRGPDPRYFCNF
KRGIGTAIQGFLPELDGEKITFEKMGEYFLNGIFAQLKAQGEPLDSLVLTVPVDSFEAYRSWLSRLCEQLPELEKIQLLD
EPTAAALGYGALAEDLKRVLVVDFGGGTVDFSLVDLNLAQGQSKPTGFILKWGRKSFAESKTQKVKTAKVLAKAGKNLGG
SDLDNWLFEYFQTQQNLPQDALSLRLVERLKIALSQKTKATEIYYNDQTFETYELTLGRSAFEEILENQGFLAQLDDLLA
QVLQQARRNGVGKEDIEAVLLVGGTSQIPLVQSWLEGYFPPEKIKRDNPFGAIAWGALQLAQGFELKDFLYHSYGIRYWN
RRHNRHDWQPIINQGQPYPMTEPLEITLGASMDQQPSIELIVGELGEQSSGTEVYFDGDRLVTQQLGANQTNVKPLNDRE
GARTIAKLDPVGYPGTDRIKLQFLVDGDRTLRVTVEDLLRNVTLIENQKVAELS

Sequences:

>Translated_534_residues
MAIAVDFGTSNTLVTRWNAAKGAPEILPLQGLSQRISPNPPLIPSLLYIENAADQKVVIGQAIGDRGLDRGPDPRYFCNF
KRGIGTAIQGFLPELDGEKITFEKMGEYFLNGIFAQLKAQGEPLDSLVLTVPVDSFEAYRSWLSRLCEQLPELEKIQLLD
EPTAAALGYGALAEDLKRVLVVDFGGGTVDFSLVDLNLAQGQSKPTGFILKWGRKSFAESKTQKVKTAKVLAKAGKNLGG
SDLDNWLFEYFQTQQNLPQDALSLRLVERLKIALSQKTKATEIYYNDQTFETYELTLGRSAFEEILENQGFLAQLDDLLA
QVLQQARRNGVGKEDIEAVLLVGGTSQIPLVQSWLEGYFPPEKIKRDNPFGAIAWGALQLAQGFELKDFLYHSYGIRYWN
RRHNRHDWQPIINQGQPYPMTEPLEITLGASMDQQPSIELIVGELGEQSSGTEVYFDGDRLVTQQLGANQTNVKPLNDRE
GARTIAKLDPVGYPGTDRIKLQFLVDGDRTLRVTVEDLLRNVTLIENQKVAELS
>Mature_533_residues
AIAVDFGTSNTLVTRWNAAKGAPEILPLQGLSQRISPNPPLIPSLLYIENAADQKVVIGQAIGDRGLDRGPDPRYFCNFK
RGIGTAIQGFLPELDGEKITFEKMGEYFLNGIFAQLKAQGEPLDSLVLTVPVDSFEAYRSWLSRLCEQLPELEKIQLLDE
PTAAALGYGALAEDLKRVLVVDFGGGTVDFSLVDLNLAQGQSKPTGFILKWGRKSFAESKTQKVKTAKVLAKAGKNLGGS
DLDNWLFEYFQTQQNLPQDALSLRLVERLKIALSQKTKATEIYYNDQTFETYELTLGRSAFEEILENQGFLAQLDDLLAQ
VLQQARRNGVGKEDIEAVLLVGGTSQIPLVQSWLEGYFPPEKIKRDNPFGAIAWGALQLAQGFELKDFLYHSYGIRYWNR
RHNRHDWQPIINQGQPYPMTEPLEITLGASMDQQPSIELIVGELGEQSSGTEVYFDGDRLVTQQLGANQTNVKPLNDREG
ARTIAKLDPVGYPGTDRIKLQFLVDGDRTLRVTVEDLLRNVTLIENQKVAELS

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=300, Percent_Identity=28.3333333333333, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI124256496, Length=275, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI24234688, Length=276, Percent_Identity=27.8985507246377, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1786196, Length=273, Percent_Identity=31.1355311355311, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786870, Length=443, Percent_Identity=24.3792325056433, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788875, Length=259, Percent_Identity=27.027027027027, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17534771, Length=317, Percent_Identity=28.391167192429, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17568549, Length=273, Percent_Identity=29.3040293040293, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17534015, Length=438, Percent_Identity=25.3424657534247, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17534013, Length=438, Percent_Identity=25.3424657534247, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17507981, Length=303, Percent_Identity=28.0528052805281, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32564617, Length=265, Percent_Identity=27.5471698113208, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324120, Length=273, Percent_Identity=31.1355311355311, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319972, Length=273, Percent_Identity=31.1355311355311, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322505, Length=403, Percent_Identity=25.3101736972705, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322426, Length=263, Percent_Identity=28.8973384030418, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319314, Length=273, Percent_Identity=29.6703296703297, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319396, Length=308, Percent_Identity=28.2467532467532, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320805, Length=401, Percent_Identity=25.1870324189526, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320950, Length=326, Percent_Identity=27.3006134969325, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653595, Length=407, Percent_Identity=23.3415233415233, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stati

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 59465; Mature: 59334

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00329 HSP70_2 ; PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAVDFGTSNTLVTRWNAAKGAPEILPLQGLSQRISPNPPLIPSLLYIENAADQKVVIG
CEEEEEECCCCCEEEEECCCCCCCCEEECCCHHHHCCCCCCCCCCEEEEECCCCCEEEEE
QAIGDRGLDRGPDPRYFCNFKRGIGTAIQGFLPELDGEKITFEKMGEYFLNGIFAQLKAQ
EHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
GEPLDSLVLTVPVDSFEAYRSWLSRLCEQLPELEKIQLLDEPTAAALGYGALAEDLKRVL
CCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCEEE
VVDFGGGTVDFSLVDLNLAQGQSKPTGFILKWGRKSFAESKTQKVKTAKVLAKAGKNLGG
EEEECCCEEEEEEEEEEHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDLDNWLFEYFQTQQNLPQDALSLRLVERLKIALSQKTKATEIYYNDQTFETYELTLGRS
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCHH
AFEEILENQGFLAQLDDLLAQVLQQARRNGVGKEDIEAVLLVGGTSQIPLVQSWLEGYFP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCCCHHHHHHHHCCCC
PEKIKRDNPFGAIAWGALQLAQGFELKDFLYHSYGIRYWNRRHNRHDWQPIINQGQPYPM
HHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
TEPLEITLGASMDQQPSIELIVGELGEQSSGTEVYFDGDRLVTQQLGANQTNVKPLNDRE
CCCEEEEECCCCCCCCCCEEEEECCCCCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCC
GARTIAKLDPVGYPGTDRIKLQFLVDGDRTLRVTVEDLLRNVTLIENQKVAELS
HHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEHHHHHCCCEEECCCCCCCCC
>Mature Secondary Structure 
AIAVDFGTSNTLVTRWNAAKGAPEILPLQGLSQRISPNPPLIPSLLYIENAADQKVVIG
EEEEEECCCCCEEEEECCCCCCCCEEECCCHHHHCCCCCCCCCCEEEEECCCCCEEEEE
QAIGDRGLDRGPDPRYFCNFKRGIGTAIQGFLPELDGEKITFEKMGEYFLNGIFAQLKAQ
EHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
GEPLDSLVLTVPVDSFEAYRSWLSRLCEQLPELEKIQLLDEPTAAALGYGALAEDLKRVL
CCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCEEE
VVDFGGGTVDFSLVDLNLAQGQSKPTGFILKWGRKSFAESKTQKVKTAKVLAKAGKNLGG
EEEECCCEEEEEEEEEEHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDLDNWLFEYFQTQQNLPQDALSLRLVERLKIALSQKTKATEIYYNDQTFETYELTLGRS
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCHH
AFEEILENQGFLAQLDDLLAQVLQQARRNGVGKEDIEAVLLVGGTSQIPLVQSWLEGYFP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCCCHHHHHHHHCCCC
PEKIKRDNPFGAIAWGALQLAQGFELKDFLYHSYGIRYWNRRHNRHDWQPIINQGQPYPM
HHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
TEPLEITLGASMDQQPSIELIVGELGEQSSGTEVYFDGDRLVTQQLGANQTNVKPLNDRE
CCCEEEEECCCCCCCCCCEEEEECCCCCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCC
GARTIAKLDPVGYPGTDRIKLQFLVDGDRTLRVTVEDLLRNVTLIENQKVAELS
HHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEHHHHHCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA