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The map label for this gene is aroA [H]

Identifier: 170076801

GI number: 170076801

Start: 175339

End: 176679

Strand: Direct

Name: aroA [H]

Synonym: SYNPCC7002_A0169

Alternate gene names: 170076801

Gene position: 175339-176679 (Clockwise)

Preceding gene: 170076799

Following gene: 170076803

Centisome position: 5.83

GC content: 55.7

Gene sequence:

>1341_bases
ATGATTCGCCTCGAAACGGTTTCTCCCCACCAGCAACTTGTGATTACGCCGCCTGCATCGGGCCTCAGTTTGCAGGGAAA
GGTGCGGATTCCGGGGGATAAGTCCATTTCCCACCGGGCGTTGATGTTGGGGGCGATCGCCGAAGGCGAAACGATCATCG
AAGGCTTGCTATTGGGCGAAGATCCCCGCAGTACGGCGGCCTGTTTCGCGGCGATGGGGGCCAATATTTCAGAATTAAAT
GAAACGGAAGTCCGGGTGCAGGGGGTCGGCCTTGGTAATTTGCAAGAACCGGACAATGTCCTTGATGCGGGCAACTCCGG
CACCACGATGCGCTTGATGATGGGTCTGCTGGCTTCGTCGCCGGATCGCTTTTTTGCCGTGACTGGAGATGGTTCCTTGC
GATCGCGCCCCATGTCCCGGGTTGTCAATCCCCTGAAGGAAATGGGGGCACAAATTTGGGGCAAAAAAGGCAATACCCTC
GCTCCCCTAGCGATTCAAGGACAACAGTTAAAGGGAATTCATTACCATTCCCCCATTGCGTCAGCCCAGGTAAAATCCTG
TGTATTGTTGGCGGGCCTCTTGGCAGAGGGGCAAACCACCGTCACCGAACCTGCCCTTTCGCGGGATCACAGTGAACGGA
TGCTCCGGGCCTTTGGCGCAAATCTCACCATTGATCCCGAAACCCACAGCGTCACTATTGACCCTCACCCGACGTTGCGG
GGCCAAAAAGTGGTGGTGCCGGGGGATATTAGTTCGGCGGCTTTTTGGATGGTGGCGGCGGCGATTGTGCCCGATTCTGA
TTTGACGATTGAGAATGTGGGGATTAATCCGACCCGCACCGGGATTATTGAAGCGATGCAGATGATGGGGGCGGACATGA
CCCTGGATAATGCGCGGGAAGTGGCCGGGGAACCGGTGGCGGATCTGCGGGTGCAATATTCTCCCCTCAAGGGTTGCACC
ATCGGCGGCGAGATTATTCCCCGGCTGATTGATGAAATTCCGATCCTGGCGGTGGCGGCCTGTTTCGCAGCAGGAACAAC
GATCATCAAAGATGCTGAGGAGTTACGGGTCAAAGAAAGCGATCGCCTCGCGGTGATGGCCGCAGAATTGACGAAAATGG
GTGCGAACATTATCGAGCATCCCGACGGCCTAGAGATCATTGGGGGCGCCTCTTTAAACGGAGCAGAAATGGATAGCTAC
ACTGACCATCGCATTGCCATGAGTTTGGCGATCGCCGCTTTAAATGCCAAAGATGAAACCCGCATCCACCGGGCCGAAGC
CGCCTCCATTTCCTATCCCACCTTTGTCGAAACCCTCACCAATGTTTGTCAGTTTGAATAG

Upstream 100 bases:

>100_bases
TGGTTAAAAAGACGAATTTGAGCGATTCTGCCCCGGGCCATAGGCAAGGGATTTGGAAATCCGCTAAGATGACATCGCCC
ATTTGTAACATCCCGACATT

Downstream 100 bases:

>100_bases
ACGTCCAGGCTAGGTTTTGCTGCCGTTAAAGCGCATTTTCACCCCCGTTGCAGGAGACAAAACTAACCCCTTGCGTTTGG
CCGCGACGGGCACTTGATCC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MIRLETVSPHQQLVITPPASGLSLQGKVRIPGDKSISHRALMLGAIAEGETIIEGLLLGEDPRSTAACFAAMGANISELN
ETEVRVQGVGLGNLQEPDNVLDAGNSGTTMRLMMGLLASSPDRFFAVTGDGSLRSRPMSRVVNPLKEMGAQIWGKKGNTL
APLAIQGQQLKGIHYHSPIASAQVKSCVLLAGLLAEGQTTVTEPALSRDHSERMLRAFGANLTIDPETHSVTIDPHPTLR
GQKVVVPGDISSAAFWMVAAAIVPDSDLTIENVGINPTRTGIIEAMQMMGADMTLDNAREVAGEPVADLRVQYSPLKGCT
IGGEIIPRLIDEIPILAVAACFAAGTTIIKDAEELRVKESDRLAVMAAELTKMGANIIEHPDGLEIIGGASLNGAEMDSY
TDHRIAMSLAIAALNAKDETRIHRAEAASISYPTFVETLTNVCQFE

Sequences:

>Translated_446_residues
MIRLETVSPHQQLVITPPASGLSLQGKVRIPGDKSISHRALMLGAIAEGETIIEGLLLGEDPRSTAACFAAMGANISELN
ETEVRVQGVGLGNLQEPDNVLDAGNSGTTMRLMMGLLASSPDRFFAVTGDGSLRSRPMSRVVNPLKEMGAQIWGKKGNTL
APLAIQGQQLKGIHYHSPIASAQVKSCVLLAGLLAEGQTTVTEPALSRDHSERMLRAFGANLTIDPETHSVTIDPHPTLR
GQKVVVPGDISSAAFWMVAAAIVPDSDLTIENVGINPTRTGIIEAMQMMGADMTLDNAREVAGEPVADLRVQYSPLKGCT
IGGEIIPRLIDEIPILAVAACFAAGTTIIKDAEELRVKESDRLAVMAAELTKMGANIIEHPDGLEIIGGASLNGAEMDSY
TDHRIAMSLAIAALNAKDETRIHRAEAASISYPTFVETLTNVCQFE
>Mature_446_residues
MIRLETVSPHQQLVITPPASGLSLQGKVRIPGDKSISHRALMLGAIAEGETIIEGLLLGEDPRSTAACFAAMGANISELN
ETEVRVQGVGLGNLQEPDNVLDAGNSGTTMRLMMGLLASSPDRFFAVTGDGSLRSRPMSRVVNPLKEMGAQIWGKKGNTL
APLAIQGQQLKGIHYHSPIASAQVKSCVLLAGLLAEGQTTVTEPALSRDHSERMLRAFGANLTIDPETHSVTIDPHPTLR
GQKVVVPGDISSAAFWMVAAAIVPDSDLTIENVGINPTRTGIIEAMQMMGADMTLDNAREVAGEPVADLRVQYSPLKGCT
IGGEIIPRLIDEIPILAVAACFAAGTTIIKDAEELRVKESDRLAVMAAELTKMGANIIEHPDGLEIIGGASLNGAEMDSY
TDHRIAMSLAIAALNAKDETRIHRAEAASISYPTFVETLTNVCQFE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=449, Percent_Identity=29.1759465478842, Blast_Score=132, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=28.4164859002169, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47321; Mature: 47321

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLETVSPHQQLVITPPASGLSLQGKVRIPGDKSISHRALMLGAIAEGETIIEGLLLGE
CEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHEECC
DPRSTAACFAAMGANISELNETEVRVQGVGLGNLQEPDNVLDAGNSGTTMRLMMGLLASS
CCCHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCC
PDRFFAVTGDGSLRSRPMSRVVNPLKEMGAQIWGKKGNTLAPLAIQGQQLKGIHYHSPIA
CCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHCCCCCCEECEEEECCCCCCCEEECCCCH
SAQVKSCVLLAGLLAEGQTTVTEPALSRDHSERMLRAFGANLTIDPETHSVTIDPHPTLR
HHHHHHHHHHHHHHHCCCCEECCCHHHCHHHHHHHHHHCCCEEECCCCCEEEECCCCCCC
GQKVVVPGDISSAAFWMVAAAIVPDSDLTIENVGINPTRTGIIEAMQMMGADMTLDNARE
CCEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHH
VAGEPVADLRVQYSPLKGCTIGGEIIPRLIDEIPILAVAACFAAGTTIIKDAEELRVKES
HCCCCHHHCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCCCC
DRLAVMAAELTKMGANIIEHPDGLEIIGGASLNGAEMDSYTDHRIAMSLAIAALNAKDET
CCEEEHHHHHHHHCCHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
RIHRAEAASISYPTFVETLTNVCQFE
HHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRLETVSPHQQLVITPPASGLSLQGKVRIPGDKSISHRALMLGAIAEGETIIEGLLLGE
CEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHEECC
DPRSTAACFAAMGANISELNETEVRVQGVGLGNLQEPDNVLDAGNSGTTMRLMMGLLASS
CCCHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCC
PDRFFAVTGDGSLRSRPMSRVVNPLKEMGAQIWGKKGNTLAPLAIQGQQLKGIHYHSPIA
CCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHCCCCCCEECEEEECCCCCCCEEECCCCH
SAQVKSCVLLAGLLAEGQTTVTEPALSRDHSERMLRAFGANLTIDPETHSVTIDPHPTLR
HHHHHHHHHHHHHHHCCCCEECCCHHHCHHHHHHHHHHCCCEEECCCCCEEEECCCCCCC
GQKVVVPGDISSAAFWMVAAAIVPDSDLTIENVGINPTRTGIIEAMQMMGADMTLDNARE
CCEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHH
VAGEPVADLRVQYSPLKGCTIGGEIIPRLIDEIPILAVAACFAAGTTIIKDAEELRVKES
HCCCCHHHCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCCCC
DRLAVMAAELTKMGANIIEHPDGLEIIGGASLNGAEMDSYTDHRIAMSLAIAALNAKDET
CCEEEHHHHHHHHCCHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
RIHRAEAASISYPTFVETLTNVCQFE
HHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA