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The map label for this gene is ribH

Identifier: 170076769

GI number: 170076769

Start: 135206

End: 135682

Strand: Direct

Name: ribH

Synonym: SYNPCC7002_A0136

Alternate gene names: 170076769

Gene position: 135206-135682 (Clockwise)

Preceding gene: 170076768

Following gene: 170076770

Centisome position: 4.49

GC content: 51.78

Gene sequence:

>477_bases
ATGGCTACCTTTGAAGGAACCTATAACGACAACACCCAAGCGCTCAAATTGGCGATCGTCATCGGTCGTTTCAATGACCT
GGTAACAAGCAAGCTCCTCGCAGGCTGCCAAGACTGTCTCCGTCGTCATGGAGTCAATACCGATCCAGAAGGAGCGCAAA
TCGATTACATTTGGGTGCCCGGCTGTTTTGAAATTTCCCTAGTCGCCAAAAAACTGGCCGATTCTGGTAAATACGATGCC
ATCATTTGTCTTGGGGCGGTGATTCGGGGCGATACTCCCCACTTTGATTACGTTGCGGCTGAAGTTTCCAAGGGAGTTGC
GGCGGCGGCGTTCCAAACGGGCGTACCGGTTATTTTTGGCGTCCTGACCACAGATACCATGCAGCAGGCCCTCGAACGGG
CCGGGATTAAGAATAACCTCGGTTGGGGCTACGCTCTCAGTGCTTTAGAAATGGCGAGTCTGATGGGAAAGATTTAA

Upstream 100 bases:

>100_bases
TCCCCCAAGGTGCAATCTTCTGCGTTGGCAACCTCAACGTGATTGCACCTTAATTTTTTTATTAATTTCCCCCTTTACAC
CTTTTCTCTACCAATCCATT

Downstream 100 bases:

>100_bases
GCTTTGGGGCGATCGCCAACGGGATCTCAAAAAAAATCAATGAGACCCTTGACATCTTCGTTTTTTCTTGGCATAGTTGT
ATACGTGCTCAGCACGCAAG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MATFEGTYNDNTQALKLAIVIGRFNDLVTSKLLAGCQDCLRRHGVNTDPEGAQIDYIWVPGCFEISLVAKKLADSGKYDA
IICLGAVIRGDTPHFDYVAAEVSKGVAAAAFQTGVPVIFGVLTTDTMQQALERAGIKNNLGWGYALSALEMASLMGKI

Sequences:

>Translated_158_residues
MATFEGTYNDNTQALKLAIVIGRFNDLVTSKLLAGCQDCLRRHGVNTDPEGAQIDYIWVPGCFEISLVAKKLADSGKYDA
IICLGAVIRGDTPHFDYVAAEVSKGVAAAAFQTGVPVIFGVLTTDTMQQALERAGIKNNLGWGYALSALEMASLMGKI
>Mature_157_residues
ATFEGTYNDNTQALKLAIVIGRFNDLVTSKLLAGCQDCLRRHGVNTDPEGAQIDYIWVPGCFEISLVAKKLADSGKYDAI
ICLGAVIRGDTPHFDYVAAEVSKGVAAAAFQTGVPVIFGVLTTDTMQQALERAGIKNNLGWGYALSALEMASLMGKI

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=47.682119205298, Blast_Score=133, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324429, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_SYNP2 (B1XLJ1)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001733407.1
- ProteinModelPortal:   B1XLJ1
- SMR:   B1XLJ1
- GeneID:   6056805
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0136
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16875; Mature: 16743

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFEGTYNDNTQALKLAIVIGRFNDLVTSKLLAGCQDCLRRHGVNTDPEGAQIDYIWVP
CCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
GCFEISLVAKKLADSGKYDAIICLGAVIRGDTPHFDYVAAEVSKGVAAAAFQTGVPVIFG
CCHHHHHHHHHHHCCCCCCHHEEEHHHHCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHH
VLTTDTMQQALERAGIKNNLGWGYALSALEMASLMGKI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATFEGTYNDNTQALKLAIVIGRFNDLVTSKLLAGCQDCLRRHGVNTDPEGAQIDYIWVP
CCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
GCFEISLVAKKLADSGKYDAIICLGAVIRGDTPHFDYVAAEVSKGVAAAAFQTGVPVIFG
CCHHHHHHHHHHHCCCCCCHHEEEHHHHCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHH
VLTTDTMQQALERAGIKNNLGWGYALSALEMASLMGKI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA