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The map label for this gene is engA

Identifier: 170076756

GI number: 170076756

Start: 124239

End: 125600

Strand: Direct

Name: engA

Synonym: SYNPCC7002_A0123

Alternate gene names: 170076756

Gene position: 124239-125600 (Clockwise)

Preceding gene: 170076752

Following gene: 170076757

Centisome position: 4.13

GC content: 52.35

Gene sequence:

>1362_bases
ATGAAACTCCCCATTATTGCCGTGATCGGTCGTCCCAACGTGGGCAAATCTACCCTCGTCAACCGCATTGCTGGCGATCA
ACAGGCGATCGTCCATGACCAGCCCGGCATTACCCGCGATCGCACCTATCGGCCTGGTTTTTGGCAAGACCGCAACTTTC
AGATTGTCGATACGGGCGGGATTGTTTTCGACGACCACGAAGAATTTTTACCTTTAATCCGCGAACAAGCGGCGATCGCC
CTCGCCGAAGCAGCCGTTGCCCTTTTTGTGGTGGATGGCCAAGCTGGGTTAAATGCCGCCGACCAAGAAATTGCCGACTG
GTTGCGCCAACAAAATGTCCCCGTTGTCCTGGCCGTGAACAAATGCGAATCCCTCGAACAGGGCTATACCCAAGCAGCTG
AATTTTGGGAGCTGGGCATGGAAGAACCTTTCCCCATCTCGGCGATCCATGGCAGTGGCACCGGCGATCTTTTAGACAAA
GTCATTGAATATCTCCCGACGATCACCGATGTCGAAGAAGATACCACCATTAACGTCGCAATCATTGGTCGCCCCAATGT
CGGTAAATCGAGTCTGCTCAATGCCCTTACCGGAGAACAACGGGCGATCGTCAGTCCGATTTCTGGGACAACCCGCGATG
CCATTGACACAATCATCGAACGCAACGGCCAACAATATCGCCTCATTGACACCGCTGGCATCCGCCGGAAAAAAAATGTG
GATTATGGGGCCGAATTTTTTAGCATTAACCGTGCCTTTAAAGCGATTCGTCGGGCGGATGTAGTACTTTTTGTGATTGA
TGTTTTAGATGGGGTGACCGAACAGGATCTCAAACTAGCGGGTCGAATCATTGACGAAGGCCGAGCGGTGATCATCGTTG
CCAACAAGTGGGATGCTGTCGAGAAGGATACCTACACGATCAACCAATACCGCAAAGAGTTGCAAGCGCGTCTATTTTTT
ATGGAATGGGCCGAAATGCTCTTCATTAGCGCCCAGACTGGTCAGCGGGTGAATAAAATTCTGGATTTAGTTGATCAAGC
CGCCGAATCTCACCGTCGCCGCGTTTCTACCGCCGTAATTAATGAGGTGATCCAAGAAGCGGTTTCCTGGCATTCTCCCC
CCACCAGTCGCCAAGGGAAACAGGGTCGGATTTACTATGGCACCCAGGTACGGAGTCAGCCGCCGACGATTTCTCTATTT
GTCAATGACCCCAAACGATTTAACGATAGCTACCGCCGCTATATCGAGAAGCAATTTCGTCAGGATCTCGGTTTTGCGGG
CACGCCGATCCGTTTGGTTTGGCGCGGTAAACGGGTGCGGGATGCAGAACGGGGCACCCCCAACCGAGCCACAAAGGTTT
AG

Upstream 100 bases:

>100_bases
ATATCATAATTTTTTGAAGCAAAACAGACCGCTTGTACTAAAGCTTAGCGAGTCCCCCCGTCATTATCCAGTCTTTTCCC
CTGATTCAAGCAGAGTCCCT

Downstream 100 bases:

>100_bases
CACAGACGATACACTGAAGGGCATCTTTGTCTGGGACACTAGGCTCTATGTCTTCTGAAAAAATGTCGCCATCGTCACCC
CCCTATGATCTAATCGTGGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKLPIIAVIGRPNVGKSTLVNRIAGDQQAIVHDQPGITRDRTYRPGFWQDRNFQIVDTGGIVFDDHEEFLPLIREQAAIA
LAEAAVALFVVDGQAGLNAADQEIADWLRQQNVPVVLAVNKCESLEQGYTQAAEFWELGMEEPFPISAIHGSGTGDLLDK
VIEYLPTITDVEEDTTINVAIIGRPNVGKSSLLNALTGEQRAIVSPISGTTRDAIDTIIERNGQQYRLIDTAGIRRKKNV
DYGAEFFSINRAFKAIRRADVVLFVIDVLDGVTEQDLKLAGRIIDEGRAVIIVANKWDAVEKDTYTINQYRKELQARLFF
MEWAEMLFISAQTGQRVNKILDLVDQAAESHRRRVSTAVINEVIQEAVSWHSPPTSRQGKQGRIYYGTQVRSQPPTISLF
VNDPKRFNDSYRRYIEKQFRQDLGFAGTPIRLVWRGKRVRDAERGTPNRATKV

Sequences:

>Translated_453_residues
MKLPIIAVIGRPNVGKSTLVNRIAGDQQAIVHDQPGITRDRTYRPGFWQDRNFQIVDTGGIVFDDHEEFLPLIREQAAIA
LAEAAVALFVVDGQAGLNAADQEIADWLRQQNVPVVLAVNKCESLEQGYTQAAEFWELGMEEPFPISAIHGSGTGDLLDK
VIEYLPTITDVEEDTTINVAIIGRPNVGKSSLLNALTGEQRAIVSPISGTTRDAIDTIIERNGQQYRLIDTAGIRRKKNV
DYGAEFFSINRAFKAIRRADVVLFVIDVLDGVTEQDLKLAGRIIDEGRAVIIVANKWDAVEKDTYTINQYRKELQARLFF
MEWAEMLFISAQTGQRVNKILDLVDQAAESHRRRVSTAVINEVIQEAVSWHSPPTSRQGKQGRIYYGTQVRSQPPTISLF
VNDPKRFNDSYRRYIEKQFRQDLGFAGTPIRLVWRGKRVRDAERGTPNRATKV
>Mature_453_residues
MKLPIIAVIGRPNVGKSTLVNRIAGDQQAIVHDQPGITRDRTYRPGFWQDRNFQIVDTGGIVFDDHEEFLPLIREQAAIA
LAEAAVALFVVDGQAGLNAADQEIADWLRQQNVPVVLAVNKCESLEQGYTQAAEFWELGMEEPFPISAIHGSGTGDLLDK
VIEYLPTITDVEEDTTINVAIIGRPNVGKSSLLNALTGEQRAIVSPISGTTRDAIDTIIERNGQQYRLIDTAGIRRKKNV
DYGAEFFSINRAFKAIRRADVVLFVIDVLDGVTEQDLKLAGRIIDEGRAVIIVANKWDAVEKDTYTINQYRKELQARLFF
MEWAEMLFISAQTGQRVNKILDLVDQAAESHRRRVSTAVINEVIQEAVSWHSPPTSRQGKQGRIYYGTQVRSQPPTISLF
VNDPKRFNDSYRRYIEKQFRQDLGFAGTPIRLVWRGKRVRDAERGTPNRATKV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=463, Percent_Identity=38.4449244060475, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=48.3516483516484, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788919, Length=170, Percent_Identity=30, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=50.5494505494505, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323665, Length=202, Percent_Identity=34.6534653465347, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SYNP2 (B1XLH8)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001733394.1
- ProteinModelPortal:   B1XLH8
- SMR:   B1XLH8
- GeneID:   6056589
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0123
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50902; Mature: 50902

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPIIAVIGRPNVGKSTLVNRIAGDQQAIVHDQPGITRDRTYRPGFWQDRNFQIVDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCC
IVFDDHEEFLPLIREQAAIALAEAAVALFVVDGQAGLNAADQEIADWLRQQNVPVVLAVN
EEECCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEH
KCESLEQGYTQAAEFWELGMEEPFPISAIHGSGTGDLLDKVIEYLPTITDVEEDTTINVA
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
IIGRPNVGKSSLLNALTGEQRAIVSPISGTTRDAIDTIIERNGQQYRLIDTAGIRRKKNV
EEECCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
DYGAEFFSINRAFKAIRRADVVLFVIDVLDGVTEQDLKLAGRIIDEGRAVIIVANKWDAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCC
EKDTYTINQYRKELQARLFFMEWAEMLFISAQTGQRVNKILDLVDQAAESHRRRVSTAVI
CCCCEEHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVIQEAVSWHSPPTSRQGKQGRIYYGTQVRSQPPTISLFVNDPKRFNDSYRRYIEKQFR
HHHHHHHHHCCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCCHHCCHHHHHHHHHHHH
QDLGFAGTPIRLVWRGKRVRDAERGTPNRATKV
HHCCCCCCCEEEEEECCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MKLPIIAVIGRPNVGKSTLVNRIAGDQQAIVHDQPGITRDRTYRPGFWQDRNFQIVDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCC
IVFDDHEEFLPLIREQAAIALAEAAVALFVVDGQAGLNAADQEIADWLRQQNVPVVLAVN
EEECCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEH
KCESLEQGYTQAAEFWELGMEEPFPISAIHGSGTGDLLDKVIEYLPTITDVEEDTTINVA
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
IIGRPNVGKSSLLNALTGEQRAIVSPISGTTRDAIDTIIERNGQQYRLIDTAGIRRKKNV
EEECCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
DYGAEFFSINRAFKAIRRADVVLFVIDVLDGVTEQDLKLAGRIIDEGRAVIIVANKWDAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCC
EKDTYTINQYRKELQARLFFMEWAEMLFISAQTGQRVNKILDLVDQAAESHRRRVSTAVI
CCCCEEHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVIQEAVSWHSPPTSRQGKQGRIYYGTQVRSQPPTISLFVNDPKRFNDSYRRYIEKQFR
HHHHHHHHHCCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCCHHCCHHHHHHHHHHHH
QDLGFAGTPIRLVWRGKRVRDAERGTPNRATKV
HHCCCCCCCEEEEEECCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA