Click here to switch to the map view.

The map label for this gene is aegA [H]

Identifier: 170026045

GI number: 170026045

Start: 4222586

End: 4224601

Strand: Reverse

Name: aegA [H]

Synonym: YPK_3831

Alternate gene names: 170026045

Gene position: 4224601-4222586 (Counterclockwise)

Preceding gene: 170026047

Following gene: 170026044

Centisome position: 90.09

GC content: 52.98

Gene sequence:

>2016_bases
ATGAATCCATTTATTGTTGCTGACGCTGAGAGCTGTATTGGTTGTCGGAGTTGTGAAGTGGCTTGTGTGGTCGCCCATCA
TGAGGGCCAGTTTCCTGATAAACCGGAATATTTCACCCCACGGGTGAAAGTATTCAAAGGCGATCAATGTGCGACGGCAG
TATTTTGCCATCATTGTGAAGATGCCCCTTGTGCCAGCACCTGCCCGAATGGTGCCATTGTTGAATTGAATAATAGTATT
CAGGTGATTCAGGAAAAATGTATTGGCTGTAAAACCTGTATGATCGCCTGCCCGTTTGGCATGATGACCGTGGTCACCGA
AACGGTTCAACCCGCCAGCCACCGCTTAGCGGATGTCTATCGGCGTACAGAAGCACAAAAATGTGACCTTTGTCTTGATC
AGCCTGATGGCCCAGCCTGTATTAAAACCTGCCCTACGCAGGCTCTGACCTTGGTGGACCAACAATATTTACTGCATCAA
CAGCAGCAAAAGCGCCAACACATGGCGCTGAATGAGCACAATGGCCGCTTGTTCAGTCGCGCGGTGGTGCAGGCGGCCAG
TGCATCGTCAAATAAAAGCATCCGCGACGCAACACCGGTTAACCTCTTGCAGCGGCCACGGGCACCACGTCTGGAGCCGA
AAAAAATTCCGTTGGCAGAGCGTAAAACGGGTTTTGCTGAAATCTATCTGCCATTTACCGAAAGCCAAATCCATGAACAG
GCTGAACGCTGCCTGGAATGCGGTGATAAAACCATCTGTCAGTGGACATGCCCACTGCATAACGCCATCCCGAAATGGAT
CTCGCTGGCCCATCAGGGGCGGATCCATGAAGCAGCAGAATTATCCCATCAAACCAGCAGCTTGCCCGAAGTGTGTGGCC
GGGTATGCCCGCAAGATCGCTTATGTGAGCAGTCCTGTACGCTGAATGACCACGATGGCGCGGTCACTATCGGGCAGATT
GAGCGGCATATCACGGAAACGGCACTGGCGACCGGCTGGCGGCCTGATCTGTCACAGGTGAAACCCAGCGGTAAACGGGT
CGCTATTATTGGCGCTGGCCCAGCAGGTTTGGGCTGTGCGGATATTCTGGTACGTAATGGCATCACGCCAGTGGTGTTTG
ATCGTTATCCCGAAATTGGCGGTTTGCTGACATTTGGTATTCCGGCTTTCAAGCTGGAAAAATCGGTGATGACTCGGCGG
AGAGAAATTTTCACCGAGATGGGCGTGGAGTTTTGCCTGAATACAGAAATTGGCCGCGATATCACCATGGAAAACCTGCT
CCACGACTTCGATGCTCTGTTCCTCGGGGTTGGGACCTACCGTTCCATGCGCTCAGGATTAGAAAATGAGGATGCTCAGG
GCGTTTACGATGTCTTGCCATTCCTGATCGGTAACACCCAGCATTTGATGGGTTACACCGCCAATGGCGCTCACCCTTAT
GTCAGTATGCAGGACCAACGCGTGGTGGTGTTGGGGGGCGGTGATACCGCCATGGATTGTGTTCGAACCTCCCTGCGTCA
GGGGGCAAGCCGCGTAGTGTGCGCGTATCGGCGTGATGAGAAGAATATGCCTGGTTCTAAACGTGAGGTGAAAAATGCGC
GTGAGGAGGGGGCTGAATTTATGTTCAACCTCCAGCCGATGAGCATTGTGGTCGATGAATCGGGACAGGTGACGGGTATC
AAGATGGTTCGCACTGAAATGGGACAGGCAGATGCCCAAGGGCGGCGACAAGCCCTGCCTATCGCCGGTTCCGAGCATCT
TATTCCTGCTGATGCCGTGATCATGGCCTTTGGTTTCAGCCCGCACCGGATGTCATGGCTGGCAGAACATAACGTGGTGC
TGGATAAACAGGGGCGCGTGGTTGCGCCGACTATCTCCGGCTATCCCTATCAAACCAGTAATCCCAAAATTTTTGCCGGT
GGCGACATTGTGCGAGGAGCTGACTTGATTGTGACCGCCATCGCGGAGGGGCGCAAAGCGGCAGAGAGTATTGCGTATTA
TTTGAACGTTTTATAA

Upstream 100 bases:

>100_bases
ATTATGTTTATAAGGTTAATTATGGGATAAGCATTGTGACGAGTTGTTGCAAATAATAACTATTTATCCGGCAATGGCAT
GACTTCTGGGAAGAAATATA

Downstream 100 bases:

>100_bases
CGCCTGCGGCCAGGAGAGAAAGATGAACCGTTTTGTTATCGCTGATATGACTCAGTGCATTGGCTGCCGGACCTGTGAAA
TCGCCTGTGTGGTGGCGCAT

Product: putative oxidoreductase Fe-S binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCEDAPCASTCPNGAIVELNNSI
QVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVYRRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQ
QQQKRQHMALNEHNGRLFSRAVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDRLCEQSCTLNDHDGAVTIGQI
ERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCADILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRR
REIFTEMGVEFCLNTEIGRDITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDVLPFLIGNTQHLMGYTANGAHPY
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEFMFNLQPMSIVVDESGQVTGI
KMVRTEMGQADAQGRRQALPIAGSEHLIPADAVIMAFGFSPHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAG
GDIVRGADLIVTAIAEGRKAAESIAYYLNVL

Sequences:

>Translated_671_residues
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCEDAPCASTCPNGAIVELNNSI
QVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVYRRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQ
QQQKRQHMALNEHNGRLFSRAVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDRLCEQSCTLNDHDGAVTIGQI
ERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCADILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRR
REIFTEMGVEFCLNTEIGRDITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDVLPFLIGNTQHLMGYTANGAHPY
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEFMFNLQPMSIVVDESGQVTGI
KMVRTEMGQADAQGRRQALPIAGSEHLIPADAVIMAFGFSPHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAG
GDIVRGADLIVTAIAEGRKAAESIAYYLNVL
>Mature_671_residues
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCEDAPCASTCPNGAIVELNNSI
QVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVYRRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQ
QQQKRQHMALNEHNGRLFSRAVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDRLCEQSCTLNDHDGAVTIGQI
ERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCADILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRR
REIFTEMGVEFCLNTEIGRDITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDVLPFLIGNTQHLMGYTANGAHPY
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEFMFNLQPMSIVVDESGQVTGI
KMVRTEMGQADAQGRRQALPIAGSEHLIPADAVIMAFGFSPHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAG
GDIVRGADLIVTAIAEGRKAAESIAYYLNVL

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=452, Percent_Identity=29.8672566371681, Blast_Score=165, Evalue=1e-40,
Organism=Escherichia coli, GI1788811, Length=670, Percent_Identity=56.5671641791045, Blast_Score=794, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=470, Percent_Identity=69.1489361702128, Blast_Score=693, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=666, Percent_Identity=51.6516516516517, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1788468, Length=445, Percent_Identity=32.3595505617978, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789067, Length=173, Percent_Identity=52.0231213872832, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI2367245, Length=167, Percent_Identity=48.502994011976, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1789243, Length=470, Percent_Identity=30.4255319148936, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87082179, Length=164, Percent_Identity=42.6829268292683, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1789079, Length=197, Percent_Identity=35.5329949238579, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082114, Length=198, Percent_Identity=34.3434343434343, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787749, Length=180, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790326, Length=165, Percent_Identity=32.1212121212121, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI2367345, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787122, Length=165, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787872, Length=163, Percent_Identity=27.6073619631902, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17570289, Length=480, Percent_Identity=34.375, Blast_Score=228, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI71984108, Length=474, Percent_Identity=29.746835443038, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17543860, Length=260, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320030, Length=465, Percent_Identity=31.6129032258064, Blast_Score=216, Evalue=7e-57,
Organism=Drosophila melanogaster, GI24665547, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24665543, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI28574881, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24665539, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640763, Length=458, Percent_Identity=29.0393013100437, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI18858217, Length=458, Percent_Identity=29.0393013100437, Blast_Score=165, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 73724; Mature: 73724

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCE
CCCEEEECCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCC
DAPCASTCPNGAIVELNNSIQVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVY
CCCCCCCCCCCCEEEECCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHH
RRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQQQQKRQHMALNEHNGRLFSR
HHHCCCCCCEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHH
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDR
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCHHH
LCEQSCTLNDHDGAVTIGQIERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCA
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCCCCCHH
DILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRRREIFTEMGVEFCLNTEIGRD
HHHHHCCCCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCC
ITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDVLPFLIGNTQHLMGYTANGAHPY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHEEEECCCCCCE
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEF
EEECCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCE
MFNLQPMSIVVDESGQVTGIKMVRTEMGQADAQGRRQALPIAGSEHLIPADAVIMAFGFS
EEECCCEEEEEECCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
PHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAGGDIVRGADLIVTAIAEGRKA
HHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCEEEECCCEECCCHHHHHHHHHHHHH
AESIAYYLNVL
HHHHHHHHHCC
>Mature Secondary Structure
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCE
CCCEEEECCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCC
DAPCASTCPNGAIVELNNSIQVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVY
CCCCCCCCCCCCEEEECCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHH
RRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQQQQKRQHMALNEHNGRLFSR
HHHCCCCCCEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHH
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDR
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCHHH
LCEQSCTLNDHDGAVTIGQIERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCA
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCCCCCHH
DILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRRREIFTEMGVEFCLNTEIGRD
HHHHHCCCCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCC
ITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDVLPFLIGNTQHLMGYTANGAHPY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHEEEECCCCCCE
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEF
EEECCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCE
MFNLQPMSIVVDESGQVTGIKMVRTEMGQADAQGRRQALPIAGSEHLIPADAVIMAFGFS
EEECCCEEEEEECCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
PHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAGGDIVRGADLIVTAIAEGRKA
HHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCEEEECCCEECCCHHHHHHHHHHHHH
AESIAYYLNVL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]