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The map label for this gene is lsrR [H]

Identifier: 170025864

GI number: 170025864

Start: 4028723

End: 4029718

Strand: Reverse

Name: lsrR [H]

Synonym: YPK_3649

Alternate gene names: 170025864

Gene position: 4029718-4028723 (Counterclockwise)

Preceding gene: 170025872

Following gene: 170025863

Centisome position: 85.93

GC content: 51.2

Gene sequence:

>996_bases
ATGATAAAAGAAAAACCAGCAGTAAAAGAAAAACCCCTGTCGTCCAACGACGAATACAAATATCCGGGTAATAGCATGAG
TGAAGAGGAACTGCTCGCTCGCGTTGCGTGGTTTTATTATCACGATGGTTTAACACAAGGGGATATTGGTGAGTTGCTGG
GGCTGGCTCGGCTTAAAGTCTCTCGATTATTGGAGAAAGGCCGGCAGTCTGGGGTGATCCGCGTCCAGATTAATTCGCGC
TATGAAGGCTGTCTGGAACTGGAAAATACCCTGCAACAGCATTTTGGCCTGAAGCATATCCGCATTCTGCCGTCTTTGGC
CTCCCTCAGTATCAGTAGCCGGTTGGGTATTGGTGCCGCCCATTTATTAATGGCGCTGATACAACCACAACAACTTTTGG
CCGTTGGTTTCGGTGAGACCACCATGTGCGCCTTGCAACATTTGAGTGGCTTTATCGCATCACAACAGGTCCGTTTAGTC
ACGTTATCCGGCGGTGTCGGCTCCTATATGACGGGGATTGGTCAGTTGGATGCGGCCTGCCAGGTCAGTATCATTCCGGC
CCCGCTGCGTGCCTCAAATGCCCATGTTGCCGACACGTTTCGCCAGGAAAACAGCGTCCGAGATGTGATGCTAGCCGCCT
GCGCGGCAGATATTGCGGTCGTTGGGATCGGTTCGGTTAATCAGCAAAAAGAAGCCACAATTTTGCGTTCGGGCTATATC
AGCGAAGGTGAGCAACTGATGTTTAGCCGTAAAGGCGCGGTTGGGGATATCCTCGGTTACTTTATCCAAGCCGATGGCGC
GTTGGTGCCAGATATGCAGATTCATCAGGAGTTGATTGGTATTTCGTTGGCTGATTTAACCACCATCCCAACCGTGATTG
GTGTCGCAGGGGGGGTAGAAAAAGCGGATGTGATTGTCGCAGCGCTGCGGGGGAGGTATGTGAATGCGTTGGTGACGGAT
GAGGTGACGGCGCGTGCAATCATTAACTTACTTTAA

Upstream 100 bases:

>100_bases
AGAAAAAAGATAAGCAGGCAAGAAAGATAAACAGATAAGAAAGATAAACAGATAAGAAAGATCAACCGGCAAGAAAGCGG
CAATAAGAGAACAATCGGCA

Downstream 100 bases:

>100_bases
TTGGGTGATTGGCTATTTCACTTGCCAGTTTGAGATTGGGCAGTGCTCGTGACCGTCACAGACTGTGTGTAGGCTCCGAT
CTCTGCGCGCGGTCCCACAG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MIKEKPAVKEKPLSSNDEYKYPGNSMSEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSR
YEGCLELENTLQQHFGLKHIRILPSLASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLV
TLSGGVGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYI
SEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTD
EVTARAIINLL

Sequences:

>Translated_331_residues
MIKEKPAVKEKPLSSNDEYKYPGNSMSEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSR
YEGCLELENTLQQHFGLKHIRILPSLASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLV
TLSGGVGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYI
SEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTD
EVTARAIINLL
>Mature_331_residues
MIKEKPAVKEKPLSSNDEYKYPGNSMSEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSR
YEGCLELENTLQQHFGLKHIRILPSLASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLV
TLSGGVGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYI
SEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTD
EVTARAIINLL

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=303, Percent_Identity=67.986798679868, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI87082414, Length=326, Percent_Identity=25.1533742331288, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35523; Mature: 35523

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEKPAVKEKPLSSNDEYKYPGNSMSEEELLARVAWFYYHDGLTQGDIGELLGLARLKV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
SRLLEKGRQSGVIRVQINSRYEGCLELENTLQQHFGLKHIRILPSLASLSISSRLGIGAA
HHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHH
HLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAAC
HHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCE
QVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYI
EEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCC
SEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLADLTTIPTVIGVAGGVE
CCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
KADVIVAALRGRYVNALVTDEVTARAIINLL
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKEKPAVKEKPLSSNDEYKYPGNSMSEEELLARVAWFYYHDGLTQGDIGELLGLARLKV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
SRLLEKGRQSGVIRVQINSRYEGCLELENTLQQHFGLKHIRILPSLASLSISSRLGIGAA
HHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHH
HLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAAC
HHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCE
QVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYI
EEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCC
SEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLADLTTIPTVIGVAGGVE
CCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
KADVIVAALRGRYVNALVTDEVTARAIINLL
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]