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The map label for this gene is murG

Identifier: 170025733

GI number: 170025733

Start: 3864202

End: 3865272

Strand: Reverse

Name: murG

Synonym: YPK_3518

Alternate gene names: 170025733

Gene position: 3865272-3864202 (Counterclockwise)

Preceding gene: 170025734

Following gene: 170025732

Centisome position: 82.43

GC content: 55.84

Gene sequence:

>1071_bases
ATGAGTGGGAAGACCAAGCGTTTGATGGTGATGGCGGGTGGAACCGGGGGGCATGTCTTCCCCGGTTTGGCCGTGGCACA
TCATTTGATGGCGCAAGGCTGGCAGGTGCGTTGGTTAGGCACTGCGGACAGAATGGAAGCGTCACTGGTTCCCCAACATG
GCATTGAAATTGATTTTATTAAAATTTCCGGCTTGCGTGGCAAAGGCCTAATGGCCCAATTGACAGCACCGATACGTATT
TATCGTGCGGTGCGTCAGGCGCAGAAAATCATGCGAGATTACCAACCCGATGTGGTGTTGGGCATGGGCGGGTATGTTTC
TGGCCCTGGTGGTTTAGCCGCCTGGCTGTGTGGCGTACCGGTGGTATTGCATGAGCAGAATGGGATTGCGGGTCTGACTA
ACCGTTGGTTGGCCAGGATCGCCAAAAAAGTTTTACAGGCATTTCCAGGGGCATTCCCCAACGCGGATGTCGTGGGTAAC
CCGGTTCGGACCGATGTACTGGCCTTGCCATTACCCGCAGTACGTTTGAGCGGCCGTGAAGGGCCGATTCGGGTCTTGGT
CATCGGTGGTAGCCAAGGCGCTCGAATACTGAATCAGACCCTGCCTTTGGTTGCTGCAAGTCTGGGCGAACAAATAACGC
TGTGGCATCAGGTCGGTAAAGGCGCACTGCCAGAGGTATCGCAGGCTTACCAACAAGCGGGGCAGGCCGGGCACCAAGTG
GTTGAATTTATCGACGATATGGCAGCGGCTTATGCCTGGGCTGATGTCGTGGTGTGCCGTTCAGGTGCACTGACGGTCAG
TGAAGTGGCGGCGGCGGGGCTACCCGCGATTTTTGTGCCATTCCAGCATAAAGATCGGCAGCAATATTGGAATGCATTGC
CGCTAGAGAAAGCGGGGGCAGCAAAAATTATTGAGCAGCCACAATTTACGGCAACCAGCGTTAGCAGCCTGCTGGCGGGT
TGGGATCGTGCAACATTACTGTCGATGGCTGAACGGGCCAGATCGGTTGCCATCCCTGACGCGACTGAGCGTGTTGCGGC
TGAAGTGGTTGCGGCCAGTAAGTCAGCGTAA

Upstream 100 bases:

>100_bases
GTTCAAGCCTGATAATTATGTCAACGGCGATAGTGCTGTTGTTACGTATTGATTTTGAAACGCGGCTGGCAAAAGCCCAG
GCGTTTGTAAGGAGTGCCCG

Downstream 100 bases:

>100_bases
AATCGCGATCACTTTGAAATAGCTACAATTTTAAATGGTTACGGTTTTGAAATAGCGATGACCTTGAAATAAACAGTGAT
CAGTGGGCGATGAATGCAGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSGKTKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEASLVPQHGIEIDFIKISGLRGKGLMAQLTAPIRI
YRAVRQAQKIMRDYQPDVVLGMGGYVSGPGGLAAWLCGVPVVLHEQNGIAGLTNRWLARIAKKVLQAFPGAFPNADVVGN
PVRTDVLALPLPAVRLSGREGPIRVLVIGGSQGARILNQTLPLVAASLGEQITLWHQVGKGALPEVSQAYQQAGQAGHQV
VEFIDDMAAAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQFTATSVSSLLAG
WDRATLLSMAERARSVAIPDATERVAAEVVAASKSA

Sequences:

>Translated_356_residues
MSGKTKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEASLVPQHGIEIDFIKISGLRGKGLMAQLTAPIRI
YRAVRQAQKIMRDYQPDVVLGMGGYVSGPGGLAAWLCGVPVVLHEQNGIAGLTNRWLARIAKKVLQAFPGAFPNADVVGN
PVRTDVLALPLPAVRLSGREGPIRVLVIGGSQGARILNQTLPLVAASLGEQITLWHQVGKGALPEVSQAYQQAGQAGHQV
VEFIDDMAAAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQFTATSVSSLLAG
WDRATLLSMAERARSVAIPDATERVAAEVVAASKSA
>Mature_355_residues
SGKTKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEASLVPQHGIEIDFIKISGLRGKGLMAQLTAPIRIY
RAVRQAQKIMRDYQPDVVLGMGGYVSGPGGLAAWLCGVPVVLHEQNGIAGLTNRWLARIAKKVLQAFPGAFPNADVVGNP
VRTDVLALPLPAVRLSGREGPIRVLVIGGSQGARILNQTLPLVAASLGEQITLWHQVGKGALPEVSQAYQQAGQAGHQVV
EFIDDMAAAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQFTATSVSSLLAGW
DRATLLSMAERARSVAIPDATERVAAEVVAASKSA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=349, Percent_Identity=80.5157593123209, Blast_Score=586, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_YERP3 (A7FM66)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402344.1
- ProteinModelPortal:   A7FM66
- SMR:   A7FM66
- STRING:   A7FM66
- GeneID:   5386538
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3387
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   YPSE349747:YPSIP31758_3387-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37760; Mature: 37629

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKTKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEASLVPQHGIEIDFI
CCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCEEEEE
KISGLRGKGLMAQLTAPIRIYRAVRQAQKIMRDYQPDVVLGMGGYVSGPGGLAAWLCGVP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
VVLHEQNGIAGLTNRWLARIAKKVLQAFPGAFPNADVVGNPVRTDVLALPLPAVRLSGRE
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCEEECCCCHHEECCCC
GPIRVLVIGGSQGARILNQTLPLVAASLGEQITLWHQVGKGALPEVSQAYQQAGQAGHQV
CCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHH
VEFIDDMAAAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEKAGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCCCC
AKIIEQPQFTATSVSSLLAGWDRATLLSMAERARSVAIPDATERVAAEVVAASKSA
HHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGKTKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEASLVPQHGIEIDFI
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCEEEEE
KISGLRGKGLMAQLTAPIRIYRAVRQAQKIMRDYQPDVVLGMGGYVSGPGGLAAWLCGVP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
VVLHEQNGIAGLTNRWLARIAKKVLQAFPGAFPNADVVGNPVRTDVLALPLPAVRLSGRE
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCEEECCCCHHEECCCC
GPIRVLVIGGSQGARILNQTLPLVAASLGEQITLWHQVGKGALPEVSQAYQQAGQAGHQV
CCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHH
VEFIDDMAAAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEKAGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCCCC
AKIIEQPQFTATSVSSLLAGWDRATLLSMAERARSVAIPDATERVAAEVVAASKSA
HHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA