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The map label for this gene is surE

Identifier: 170025643

GI number: 170025643

Start: 3762017

End: 3762781

Strand: Reverse

Name: surE

Synonym: YPK_3428

Alternate gene names: 170025643

Gene position: 3762781-3762017 (Counterclockwise)

Preceding gene: 170025644

Following gene: 170025642

Centisome position: 80.24

GC content: 51.37

Gene sequence:

>765_bases
ATGATACGGATATTATTGAGTAACGATGATGGCATCTCTGCGCCAGGGATCCAGACGCTGGCCAGTGCATTGCGGGAATT
TGCTCAGGTGCAAATTGTAGCACCCGATCGTAACCGCAGTGGCGCTTCCAATGCATTGACTCTGGATAGTGCATTGCGGA
TCACCACCTTATCTAATGGTGATATTGCGGTGCAGCAAGGGACTCCCACCGATTGCGTCTATCTGGGCGTGAATGCGCTG
ATGCGCCCACGGCCTGACATCGTTGTCTCTGGCATTAATGCTGGCCCTAATTTAGGGGATGATGTTATCTATTCGGGTAC
CGTAGCGGCGGCGATGGAAGGGCGTCATTTGGGCTACCCAGCCTTGGCTGTCTCGCTCAACGGTCATCAGCATTATGATA
CGGCGGCGGCAGTGACTTGCCGTTTATTACGTGCGTTACAGCGCAAACCACTGCGTACCGGCAAGATCCTCAATATAAAT
GTGCCTGATTTGCCTTTATCGGAAATTAAAGGGATTCGGGTGACGCGTTGTGGTAGCCGCCATCCGGCAGAGCAGGTATT
TTGTCAGCAAGATCCCAGAGGGCAAGATCTTTATTGGATCGGGCCGCCGGGTGAAAAGTATGATGCTGGGCCAGATACTG
ACTTTGCGGCGGTTGAACAAGGTTATGTATCGATAACGCCGCTTCAAGTCGATTTAACAGCTTATACGGCACAAGAAGTG
GTTGAAAGTTGGTTAGCCAATACTGAGGTTGACGGGGAATGGTAA

Upstream 100 bases:

>100_bases
AACTGGTGGGATGATGTCACTCTTGAGCTGAGTTTCTGGCTCCCTGCGGGGAGCTTTGCGACCAGTGTAGTGAGGGAAAT
AATGAACCAGGATCGGGCTG

Downstream 100 bases:

>100_bases
ATAAACGCATGCAAACATTGTTGATGCAGTTACGTCAGCAAGGTATTCACGACGAACGCCTGTTACAGGCGATCGAAGCG
GTACCGCGTGAGCGTTTTGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MIRILLSNDDGISAPGIQTLASALREFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNAL
MRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNIN
VPDLPLSEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYTAQEV
VESWLANTEVDGEW

Sequences:

>Translated_254_residues
MIRILLSNDDGISAPGIQTLASALREFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNAL
MRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNIN
VPDLPLSEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYTAQEV
VESWLANTEVDGEW
>Mature_254_residues
MIRILLSNDDGISAPGIQTLASALREFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNAL
MRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNIN
VPDLPLSEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYTAQEV
VESWLANTEVDGEW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=80.6324110671937, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_YERP3 (A7FLX5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402253.1
- ProteinModelPortal:   A7FLX5
- SMR:   A7FLX5
- STRING:   A7FLX5
- GeneID:   5386871
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3296
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   DCVKMGI
- ProtClustDB:   PRK00346
- BioCyc:   YPSE349747:YPSIP31758_3296-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11

Molecular weight: Translated: 27289; Mature: 27289

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRILLSNDDGISAPGIQTLASALREFAQVQIVAPDRNRSGASNALTLDSALRITTLSNG
CEEEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEECCEEEEEEECCC
DIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYP
CEEEECCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCC
ALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNINVPDLPLSEIKGIRVTRCGSR
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCEEEEECCCC
HPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYTAQEV
CCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEEEEEHHHHHHHH
VESWLANTEVDGEW
HHHHHHCCCCCCCC
>Mature Secondary Structure
MIRILLSNDDGISAPGIQTLASALREFAQVQIVAPDRNRSGASNALTLDSALRITTLSNG
CEEEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEECCEEEEEEECCC
DIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYP
CEEEECCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCC
ALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNINVPDLPLSEIKGIRVTRCGSR
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCEEEEECCCC
HPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYTAQEV
CCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEEEEEHHHHHHHH
VESWLANTEVDGEW
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA