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The map label for this gene is bioC [H]

Identifier: 170025151

GI number: 170025151

Start: 3227335

End: 3228138

Strand: Reverse

Name: bioC [H]

Synonym: YPK_2929

Alternate gene names: 170025151

Gene position: 3228138-3227335 (Counterclockwise)

Preceding gene: 170025152

Following gene: 170025150

Centisome position: 68.84

GC content: 54.1

Gene sequence:

>804_bases
ATGGCCTCTGTCACTGAGCACGCGCAATGGGGCGTTGGGTGTTTACCGCCACTGAACGTTGATAAACAGGCGATTGCGGC
TGCATTCAGCCGGGCCGCCGAGAGCTACGACAGCGCGGCTGATTTACAGCGAGAAACGGGTCATCGGTTAGTGCAGTTGG
GCCAGCAGCATACGGGTTTTGTGGTGTTGGATGCGGGTTGTGGCACGGGGCATTTCAGCCAGCATTGGCGCTTGTTGGGT
AAGCGGGTCATTGCCTTGGATCTGGCGGCAGGTATGTTGGATCATGCGCGCCAACAGCAGGTCGCTGACGACTATCTGCT
GGGGGATATTGAACATATTCCACTGCCTGATCAGTCGGTGGATATCTGCTTTAGCAATTTGGCGGTGCAATGGTGTTCAG
ATCTGGGGGCGGCATTGAGTGAATTCTACCGAGTGACGCGCCCCGGCGGGATCATCCTATTTTCTACCTTGGCAGAAGGC
TCCCTTGATGAATTAGGGCAAGCGTGGCAACAGGTGGATGGTCAGCGTCATGTAAATGATTTTTTGCCATTGCAACATAT
CCAGACGGCCTGCCAATATTATCGCCATCACCTAACAACCGCGTTATATCAGCCACGGTTTCCTAACGTGATAGCGCTGA
TGCGCTCGTTACAAGGCATTGGTGCCACGCACTTGCATCATGGGCGTCAGGCTGGGTTACAGGGGCGTCAACGTCTGGCG
GCGCTACAACGGGCCTATGTCATGCAATCTGGCGGCTATCCACTGAGTTATCATATGGTTTATGGGGTTATCTATCGTGA
CTAA

Upstream 100 bases:

>100_bases
ATCCGCCCCCCCACGGTGCCACCAGGAAGCGCCAGATTGCGCATTACCCTCAGCGCGGCTCACCAACCCGAGGATATCGA
TAGATTATTGGAGGTGCTTT

Downstream 100 bases:

>100_bases
ACGTTGGTTTATCACCGGTACCGATACTGATGTCGGTAAAACCGTCGCCAGTTGTGCATTACTGCAAGCGGCCACCGCTC
AGGGGTACCATACTGCTGGC

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MASVTEHAQWGVGCLPPLNVDKQAIAAAFSRAAESYDSAADLQRETGHRLVQLGQQHTGFVVLDAGCGTGHFSQHWRLLG
KRVIALDLAAGMLDHARQQQVADDYLLGDIEHIPLPDQSVDICFSNLAVQWCSDLGAALSEFYRVTRPGGIILFSTLAEG
SLDELGQAWQQVDGQRHVNDFLPLQHIQTACQYYRHHLTTALYQPRFPNVIALMRSLQGIGATHLHHGRQAGLQGRQRLA
ALQRAYVMQSGGYPLSYHMVYGVIYRD

Sequences:

>Translated_267_residues
MASVTEHAQWGVGCLPPLNVDKQAIAAAFSRAAESYDSAADLQRETGHRLVQLGQQHTGFVVLDAGCGTGHFSQHWRLLG
KRVIALDLAAGMLDHARQQQVADDYLLGDIEHIPLPDQSVDICFSNLAVQWCSDLGAALSEFYRVTRPGGIILFSTLAEG
SLDELGQAWQQVDGQRHVNDFLPLQHIQTACQYYRHHLTTALYQPRFPNVIALMRSLQGIGATHLHHGRQAGLQGRQRLA
ALQRAYVMQSGGYPLSYHMVYGVIYRD
>Mature_266_residues
ASVTEHAQWGVGCLPPLNVDKQAIAAAFSRAAESYDSAADLQRETGHRLVQLGQQHTGFVVLDAGCGTGHFSQHWRLLGK
RVIALDLAAGMLDHARQQQVADDYLLGDIEHIPLPDQSVDICFSNLAVQWCSDLGAALSEFYRVTRPGGIILFSTLAEGS
LDELGQAWQQVDGQRHVNDFLPLQHIQTACQYYRHHLTTALYQPRFPNVIALMRSLQGIGATHLHHGRQAGLQGRQRLAA
LQRAYVMQSGGYPLSYHMVYGVIYRD

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI40018642, Length=222, Percent_Identity=25.2252252252252, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1786994, Length=251, Percent_Identity=49.800796812749, Blast_Score=217, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29552; Mature: 29421

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCEEEEHHEEEEECC
>Mature Secondary Structure 
ASVTEHAQWGVGCLPPLNVDKQAIAAAFSRAAESYDSAADLQRETGHRLVQLGQQHTGF
CCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVLDAGCGTGHFSQHWRLLGKRVIALDLAAGMLDHARQQQVADDYLLGDIEHIPLPDQSV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DICFSNLAVQWCSDLGAALSEFYRVTRPGGIILFSTLAEGSLDELGQAWQQVDGQRHVND
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
FLPLQHIQTACQYYRHHLTTALYQPRFPNVIALMRSLQGIGATHLHHGRQAGLQGRQRLA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHH
ALQRAYVMQSGGYPLSYHMVYGVIYRD
HHHHHHHHHCCCCCEEEEHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]