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The map label for this gene is potC [C]

Identifier: 170024402

GI number: 170024402

Start: 2408409

End: 2409245

Strand: Direct

Name: potC [C]

Synonym: YPK_2170

Alternate gene names: 170024402

Gene position: 2408409-2409245 (Clockwise)

Preceding gene: 170024401

Following gene: 170024403

Centisome position: 51.36

GC content: 52.09

Gene sequence:

>837_bases
ATGAGCCGCACCACCAATGGCCGCCTGGTGGTCACGATTTCGCTGGTTTTTTTCGCCATTGCCAATCTACTGTGGCTGGG
GCTACCGTTCGGTATGGCGATCCTCTGGTCACTGGTTGACCCTCAGTATCCCTGGAGCTATCCAGATATTTTCCCACAGG
TGCTGTCATTTAACCGCTGGCTGCTGGTCTGGGAAAAAACCTCACTTTCCGAAGCACTGATTAACAGTTACACCATCGCG
CCCGTGGTGGCAGCCACCAGCCTACTGCTATCGCTACCTACCGCGTATGCCTTCGGGCGCATGAGATTTCGCGGCAAGGC
AGTGGCGGAGATGCTAACCCTGATCCCGCTAGTGATGCCGGGAATGATTATCGGTATCTTCTTCAGCGCCATGCTAATGA
ACCTCAATATCAGCAACCCGTTTTTCAGCATCGTGTTGGGCCATACCGTGCTGACGCTACCCTACTCCATCCGCATTATG
TCCGCGGGGTTTAAGGCAGTACCACAGGATCTGATCGATGCCAGCCGCGATCTGGGTGCTGGCATATGGGGCACCTTCTG
CAACGCCTACCTGCCGCTGCTAAAACCGAGTTTTTTGGCAGCGCTGATTTTCTGCTTGGTGAAAAGTCTAGAAGAATTCA
GCATCGCTTATGTCCTTGGCGCACCAGATTTTATTACCGTTCCGACCATTCTTTATTCCTTCCTCGGCTACTCCTTTGTC
CGCCCAGATGCAGCGGTGGTATCAATGATTCTGGTGATCCCAAATGTCATTTTGATGATCATCATTGAGAAGCTTTTGAA
GGGTAATTATCTGTCACAGTCCACCGGGAAAGCCTGA

Upstream 100 bases:

>100_bases
CTGCCGTGATCGCCGTCATTATTATGACCACCGCGGCTATTTTTACGCTGCTGATTGCCACTTTAATCACACCGTTCGTC
ACCCGTAAAGGAGACGTCAA

Downstream 100 bases:

>100_bases
TTTTACAGGAGATAATCACATGAAAAAAACACTGATAACGCTAATGAGCGGGCTGTTATTCAGTTCGCTAACACTCGCAG
CCCAGACCAGCGACTGGGAC

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSRTTNGRLVVTISLVFFAIANLLWLGLPFGMAILWSLVDPQYPWSYPDIFPQVLSFNRWLLVWEKTSLSEALINSYTIA
PVVAATSLLLSLPTAYAFGRMRFRGKAVAEMLTLIPLVMPGMIIGIFFSAMLMNLNISNPFFSIVLGHTVLTLPYSIRIM
SAGFKAVPQDLIDASRDLGAGIWGTFCNAYLPLLKPSFLAALIFCLVKSLEEFSIAYVLGAPDFITVPTILYSFLGYSFV
RPDAAVVSMILVIPNVILMIIIEKLLKGNYLSQSTGKA

Sequences:

>Translated_278_residues
MSRTTNGRLVVTISLVFFAIANLLWLGLPFGMAILWSLVDPQYPWSYPDIFPQVLSFNRWLLVWEKTSLSEALINSYTIA
PVVAATSLLLSLPTAYAFGRMRFRGKAVAEMLTLIPLVMPGMIIGIFFSAMLMNLNISNPFFSIVLGHTVLTLPYSIRIM
SAGFKAVPQDLIDASRDLGAGIWGTFCNAYLPLLKPSFLAALIFCLVKSLEEFSIAYVLGAPDFITVPTILYSFLGYSFV
RPDAAVVSMILVIPNVILMIIIEKLLKGNYLSQSTGKA
>Mature_277_residues
SRTTNGRLVVTISLVFFAIANLLWLGLPFGMAILWSLVDPQYPWSYPDIFPQVLSFNRWLLVWEKTSLSEALINSYTIAP
VVAATSLLLSLPTAYAFGRMRFRGKAVAEMLTLIPLVMPGMIIGIFFSAMLMNLNISNPFFSIVLGHTVLTLPYSIRIMS
AGFKAVPQDLIDASRDLGAGIWGTFCNAYLPLLKPSFLAALIFCLVKSLEEFSIAYVLGAPDFITVPTILYSFLGYSFVR
PDAAVVSMILVIPNVILMIIIEKLLKGNYLSQSTGKA

Specific function: May participate in oleandomycin secretion during antibiotic production [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=221, Percent_Identity=24.4343891402715, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787714, Length=208, Percent_Identity=27.8846153846154, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30664; Mature: 30533

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTTNGRLVVTISLVFFAIANLLWLGLPFGMAILWSLVDPQYPWSYPDIFPQVLSFNRW
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCE
LLVWEKTSLSEALINSYTIAPVVAATSLLLSLPTAYAFGRMRFRGKAVAEMLTLIPLVMP
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMIIGIFFSAMLMNLNISNPFFSIVLGHTVLTLPYSIRIMSAGFKAVPQDLIDASRDLGA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHEEEECCCCHHCCHHHHHHHHHCCC
GIWGTFCNAYLPLLKPSFLAALIFCLVKSLEEFSIAYVLGAPDFITVPTILYSFLGYSFV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCHHHC
RPDAAVVSMILVIPNVILMIIIEKLLKGNYLSQSTGKA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SRTTNGRLVVTISLVFFAIANLLWLGLPFGMAILWSLVDPQYPWSYPDIFPQVLSFNRW
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCE
LLVWEKTSLSEALINSYTIAPVVAATSLLLSLPTAYAFGRMRFRGKAVAEMLTLIPLVMP
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMIIGIFFSAMLMNLNISNPFFSIVLGHTVLTLPYSIRIMSAGFKAVPQDLIDASRDLGA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHEEEECCCCHHCCHHHHHHHHHCCC
GIWGTFCNAYLPLLKPSFLAALIFCLVKSLEEFSIAYVLGAPDFITVPTILYSFLGYSFV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCHHHC
RPDAAVVSMILVIPNVILMIIIEKLLKGNYLSQSTGKA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8244027 [H]