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The map label for this gene is nudG [H]

Identifier: 170024320

GI number: 170024320

Start: 2315452

End: 2315838

Strand: Direct

Name: nudG [H]

Synonym: YPK_2086

Alternate gene names: 170024320

Gene position: 2315452-2315838 (Clockwise)

Preceding gene: 170024319

Following gene: 170024325

Centisome position: 49.38

GC content: 54.26

Gene sequence:

>387_bases
ATGATTGATGTCGTCGCCGCCATTATAGAACGGGATGGGAAGATATTACTGGCCCAGCGGGATGGGCAAAGCGATCAAGC
AGGGCTGTGGGAATTTCCTGGAGGCAAAGTTGAGGCTGGAGAAACCCAGCCTCAGGCGCTGATCCGTGAGCTTGCCGAAG
AGTTAGGTATCGAGGCCACTGTCGCTGGGTATATCGCAACCAACCAATGGGTAGCAGCCAATAACCGTATCCGCTTACAT
GCCTGGTATGTTAACCATTTTAGCGGAGAGCCAGTAAGGCATTGCCATGCGGCGTTTATCTGGCTGACGCCGCTGGAGGC
GTACCGCTACTCTCTGGCGCCCGCAGATATTCCGCTGCTAGACGCGTTTATCGCACAGAGACAATAA

Upstream 100 bases:

>100_bases
TAATGTCTGCGCCCTGTTTAAATACAGGGCCACCTCTCAAGCGTATTAAGCACATTTATCCGTCATTAGGTAAATTTATC
CATAATCAGGTAAACACGAA

Downstream 100 bases:

>100_bases
ACCTACAGAGAACTATCTGGTTAGTCTTTTCCAAATCAGTGGATTGGTGCCAATAACACCGGCATCACGCACACATTGTA
AAATCTCACCTTCAATCCGT

Product: pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MIDVVAAIIERDGKILLAQRDGQSDQAGLWEFPGGKVEAGETQPQALIRELAEELGIEATVAGYIATNQWVAANNRIRLH
AWYVNHFSGEPVRHCHAAFIWLTPLEAYRYSLAPADIPLLDAFIAQRQ

Sequences:

>Translated_128_residues
MIDVVAAIIERDGKILLAQRDGQSDQAGLWEFPGGKVEAGETQPQALIRELAEELGIEATVAGYIATNQWVAANNRIRLH
AWYVNHFSGEPVRHCHAAFIWLTPLEAYRYSLAPADIPLLDAFIAQRQ
>Mature_128_residues
MIDVVAAIIERDGKILLAQRDGQSDQAGLWEFPGGKVEAGETQPQALIRELAEELGIEATVAGYIATNQWVAANNRIRLH
AWYVNHFSGEPVRHCHAAFIWLTPLEAYRYSLAPADIPLLDAFIAQRQ

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=127, Percent_Identity=65.3543307086614, Blast_Score=161, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14236; Mature: 14236

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVVAAIIERDGKILLAQRDGQSDQAGLWEFPGGKVEAGETQPQALIRELAEELGIEAT
CHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHCCCEE
VAGYIATNQWVAANNRIRLHAWYVNHFSGEPVRHCHAAFIWLTPLEAYRYSLAPADIPLL
EEEEEECCCEEECCCEEEEEEEEEECCCCCCHHHHEEEEEEECCHHHHHEECCCCCCHHH
DAFIAQRQ
HHHHHCCC
>Mature Secondary Structure
MIDVVAAIIERDGKILLAQRDGQSDQAGLWEFPGGKVEAGETQPQALIRELAEELGIEAT
CHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHCCCEE
VAGYIATNQWVAANNRIRLHAWYVNHFSGEPVRHCHAAFIWLTPLEAYRYSLAPADIPLL
EEEEEECCCEEECCCEEEEEEEEEECCCCCCHHHHEEEEEEECCHHHHHEECCCCCCHHH
DAFIAQRQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]