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The map label for this gene is exbB [H]

Identifier: 170022923

GI number: 170022923

Start: 736462

End: 737499

Strand: Direct

Name: exbB [H]

Synonym: YPK_0672

Alternate gene names: 170022923

Gene position: 736462-737499 (Clockwise)

Preceding gene: 170022920

Following gene: 170022924

Centisome position: 15.7

GC content: 51.83

Gene sequence:

>1038_bases
GTGAAAATAGCTGGCAAAGAGAGTAAAGAGATATCACGAGTGCAAGGCCGGGTGATGAAAGGCGTGATGGTATTATTACT
GGCTACAGGTTTAGCGGGCCATGCACAAGCCGCACCAGGCAACGGCAGTGCGGTTGCGGCTACGGTTACCGCACCTACAG
CGGCAACGTCAACCCCGTTACCTGCACCAGAAATTACCTCGGTTGCTGCAATACCGGAATCAACACCAGAGTCAGTATTA
ACATCAGCATCAGCATTAACCTCAGAATCAATACCGGCCCCTATGGTTCAGCCCGTTACGGCTCCAGTATCACAAAAGCT
GGCGATGGATTTATCTGTCTGGGGTATGTATCAGAATGCGGACGTGGTTGTTAAAGGCGTCATGATTGGCCTGGTGCTGG
CTTCTATCGTCACTTGGACCATTCTGTTCTCTAAAGGGACTGAATTGTTCCGCGCTCGTCGTCGGTTGCGCCAAGAGCAT
GAAGTGATTGGGGCCGTGACCGATCTTGATACCGCTTCAGAGCGAGCAGAAGATTTTGGTCAAGGCAGCGTAAGCAGTTT
GTTACTGCGTGAAGCACTGAACGAGCGCCTGTTGTCGATAGAGTCAAATGACAATAATGGCATTAAAGAACGTACTGCTT
TCCGTTTGGAGCGCCGGGTAGCCGCCATTGGTCGCCAAATGGGCAAAGGTAATGGCTTCCTGGCAACGATCGGCGCGATT
TCCCCCTTTGTCGGTTTGTTTGGTACGGTTTGGGGCATCATGAACAGCTTTATCGGCATTGCCCACTCACAGACCACCAA
TCTGGCGGTTGTCGCACCAGGGATTGCCGAAGCATTATTGGCAACGGCGTTAGGGCTGGTGGCTGCGATCCCAGCGGTCG
TTATTTATAATATCTTTGCTCGCCAGATCGGAAATTATCGCGCTCAAGTAGGTGATGTCGCGGCACAAGTGTTACTGCTG
TTGAGCCGTGATTTGGATTTGGCCAGTAGCGCCGAAGTAAAGTCCCCTCGCCATCCTCATCAATTACGAGCAGGGTGA

Upstream 100 bases:

>100_bases
CAAATACTAATGATAATTACTATCAATCCGCTGTTTGTTTGATATGATCAAAAGCTGATTTTGTCCTTAAATTGACATGC
ATATTGGGTGGAGGCGCAGC

Downstream 100 bases:

>100_bases
TTTATGGCAATGCGAATGAATGATTCCCTCGACGAGAGTGGAGAATTACACGAAATTAACGTGACGCCGTTTATTGATGT
CATGTTGGTGCTGCTGATTA

Product: tonB-system energizer ExbB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIPESTPESVL
TSASALTSESIPAPMVQPVTAPVSQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEH
EVIGAVTDLDTASERAEDFGQGSVSSLLLREALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLL
LSRDLDLASSAEVKSPRHPHQLRAG

Sequences:

>Translated_345_residues
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIPESTPESVL
TSASALTSESIPAPMVQPVTAPVSQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEH
EVIGAVTDLDTASERAEDFGQGSVSSLLLREALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLL
LSRDLDLASSAEVKSPRHPHQLRAG
>Mature_345_residues
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIPESTPESVL
TSASALTSESIPAPMVQPVTAPVSQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEH
EVIGAVTDLDTASERAEDFGQGSVSSLLLREALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLL
LSRDLDLASSAEVKSPRHPHQLRAG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=236, Percent_Identity=71.1864406779661, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI1786958, Length=92, Percent_Identity=47.8260869565217, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 36132; Mature: 36132

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
PAPEITSVAAIPESTPESVLTSASALTSESIPAPMVQPVTAPVSQKLAMDLSVWGMYQNA
CCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCC
DVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
QGSVSSLLLREALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
CCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
PAPEITSVAAIPESTPESVLTSASALTSESIPAPMVQPVTAPVSQKLAMDLSVWGMYQNA
CCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCC
DVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
QGSVSSLLLREALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
CCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]