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The map label for this gene is shlB [H]

Identifier: 170022347

GI number: 170022347

Start: 99670

End: 101433

Strand: Direct

Name: shlB [H]

Synonym: YPK_0086

Alternate gene names: 170022347

Gene position: 99670-101433 (Clockwise)

Preceding gene: 170022346

Following gene: 170022348

Centisome position: 2.13

GC content: 45.98

Gene sequence:

>1764_bases
ATGACATTTAAAATAAATGTGAGGTGGAGGGATAAAATTGGAGATTTTTGGTGGGGGATATTGTGCCTATTATATCTTCA
AATTATGATTGGGATGCTTCCGTTTAAAGTTTTTGCTGAAATGGCGTTGCCAGAAATGGACCTGCTTGAAATGGATATAG
CCGAGCCGCAGATCCCAAATAGTATTATTCCTCCTCTATCACATGCTCAACTGGCCAGTGAACCGGTTCTGCCAGAGAAT
CTTTATAATGATGAAGTACAATGTGTAGCAATTAATAATGTCGAATTGATTAATCTTGATGCTTTCCCAAATGCAGCTCA
CTTAAAAGAAAAGGCTGAAGAAGCTCACGGGCGTTGCTTGGGGGAACAGGGGCTGTCAGTGCTTGTGGCTAACTTACAGC
AACAATTAGTGGTTGATGGCTATATCACGTCTCGTGTGGTTTTTGTCGATGACAGTGAGCGTGACGGTACTTTAATGCTG
AAATTAATGCCCGGCAGGATTGAGGATATCAGGCATCATCAAGATAGCGTCGGCAATGCTCATCTCAGCTCCCTTTTCCC
CGGTAAACGTGGTGATTTGGTTAATTTACGCCATCTTGAGCAAGGATTAGAAAACTTGCAGCGTTTGCCTTCAGTGAATG
CCACCCTGGATGTCGAATTAAACCGGGAAGATTTAAGCAGCCAGATTATCGTGAATCGCCAGCAATCACGTCTCTGGCGT
ATTAATGCCTACCTTGATGATGCGGGGCATGATGCCGTTGGCCGCTATCGTACGGGCCTGATATTGTCTTTTGATAATCC
ATTATCCCGTTATAACCCCTTGTCTCTCAGTGATTTACTCTACTTCTCTGTTAACCGTGACCTTGATAGCCAACCCGATA
AAGGGCACAACAGCTACGGGGTTCATTATTCTGTCCCGTATGGCAACTGGCTATTTAGCATGACGGGCAATCAAGGTGAG
CGTTATCAATCGTTCTCTTTTGCCGGTAAAAGACTTGCCGGTAAAAAATTTGGCTATCGTTCCCATTGGTCTGTATTGGA
TACACAAATTCAACATTTACTCACCCGTGGAGTAAATTATAAAACAGTGGGTTATGCCGGGGTGTTAATTCGTCAGTCTG
CCAGTTTTTGGACCCATCGGGAGATAGATATTCAGCGGTTCAATACCACGGACTGGCAGCTAGGGATTGAGCATCTACAT
TACATGCCATGGGCGACTTTCAGAGGGGGGGTTCGTTATCAACAGGGGGCTTCATGGTTTGGTGCCCAACCTATTCCCGG
TAAAATGAGCACTGCACCGGCGAGGTTGGTCGATATCACCAGCTCACTGGATATCCCTTTTAAGATCGGAACACAGTCCT
TCCAGTATCGGCCCGCTTTCAGCCAGCAACATACCTACTCGGATATTAGTTCACTGGATAAATTTACGATTGGTGGCAGG
AGTTCAGTGCGAGGTTTTAATGAGAATAACGCTCTGACGGGGTCGCGGGGGTGGTCTCTAAAAAATGATATTTCATGGAT
CAGCCCGATACCCGGCCAGACATTCGTGGGCCAGCAATTCTATATCGGCATGGATTATGGTGAGGTGAGTGAGCAGGGCC
AACCATTTCTTTTGGGCGAGCGTTTAGCGGGGGCCGTGGTAGGGACTCGTGGAAATTATCATGCGTTTGGTTACGATTTT
AATGTCGGCGTGCCGATAACCAAACCCGCTGAATTTGATGCTGATCCGTTGGTTTTTGGGTTTACGCTAACTTGGCAATA
TTAG

Upstream 100 bases:

>100_bases
TAAGTGAGAGATGATTTTTTATTTAAAGTTAGTTGCTTTCGTGGCTAACTTTTATTGATTTTGTATTAATCATGTTTTGA
TTGAAATGGAGTTCATTAGC

Downstream 100 bases:

>100_bases
GGTCTATACCTTCTCTGATGTTGAGTGTTTACTGTGCTGCCCTGATTAGGGGCATCACTATGGTGCACCTCTTTGGGAAG
CTATGTGGTTTCTTGGGTGA

Product: polypeptide-transport-associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MTFKINVRWRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPNSIIPPLSHAQLASEPVLPEN
LYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCLGEQGLSVLVANLQQQLVVDGYITSRVVFVDDSERDGTLML
KLMPGRIEDIRHHQDSVGNAHLSSLFPGKRGDLVNLRHLEQGLENLQRLPSVNATLDVELNREDLSSQIIVNRQQSRLWR
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYGVHYSVPYGNWLFSMTGNQGE
RYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNYKTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLH
YMPWATFRGGVRYQQGASWFGAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGERLAGAVVGTRGNYHAFGYDF
NVGVPITKPAEFDADPLVFGFTLTWQY

Sequences:

>Translated_587_residues
MTFKINVRWRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPNSIIPPLSHAQLASEPVLPEN
LYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCLGEQGLSVLVANLQQQLVVDGYITSRVVFVDDSERDGTLML
KLMPGRIEDIRHHQDSVGNAHLSSLFPGKRGDLVNLRHLEQGLENLQRLPSVNATLDVELNREDLSSQIIVNRQQSRLWR
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYGVHYSVPYGNWLFSMTGNQGE
RYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNYKTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLH
YMPWATFRGGVRYQQGASWFGAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGERLAGAVVGTRGNYHAFGYDF
NVGVPITKPAEFDADPLVFGFTLTWQY
>Mature_586_residues
TFKINVRWRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPNSIIPPLSHAQLASEPVLPENL
YNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCLGEQGLSVLVANLQQQLVVDGYITSRVVFVDDSERDGTLMLK
LMPGRIEDIRHHQDSVGNAHLSSLFPGKRGDLVNLRHLEQGLENLQRLPSVNATLDVELNREDLSSQIIVNRQQSRLWRI
NAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYGVHYSVPYGNWLFSMTGNQGER
YQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNYKTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLHY
MPWATFRGGVRYQQGASWFGAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGRS
SVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGERLAGAVVGTRGNYHAFGYDFN
VGVPITKPAEFDADPLVFGFTLTWQY

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 66270; Mature: 66139

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKINVRWRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPN
CEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCC
SIIPPLSHAQLASEPVLPENLYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCL
CCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHCCCH
GEQGLSVLVANLQQQLVVDGYITSRVVFVDDSERDGTLMLKLMPGRIEDIRHHQDSVGNA
HHHHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCC
HLSSLFPGKRGDLVNLRHLEQGLENLQRLPSVNATLDVELNREDLSSQIIVNRQQSRLWR
HHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCEEEECCCCCEEE
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYG
EEEEECCCCCCCCCHHHCEEEEEECCCHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCC
VHYSVPYGNWLFSMTGNQGERYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNY
EEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCE
KTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLHYMPWATFRGGVRYQQGASWF
EEECEEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCHHHCCCEEECCCCCCC
GAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEECCCCCCCCCHHHHHHHHHEECCCC
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCCEEEHH
RLAGAVVGTRGNYHAFGYDFNVGVPITKPAEFDADPLVFGFTLTWQY
HHCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
TFKINVRWRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPN
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCC
SIIPPLSHAQLASEPVLPENLYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCL
CCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHCCCH
GEQGLSVLVANLQQQLVVDGYITSRVVFVDDSERDGTLMLKLMPGRIEDIRHHQDSVGNA
HHHHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCC
HLSSLFPGKRGDLVNLRHLEQGLENLQRLPSVNATLDVELNREDLSSQIIVNRQQSRLWR
HHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCEEEECCCCCEEE
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYG
EEEEECCCCCCCCCHHHCEEEEEECCCHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCC
VHYSVPYGNWLFSMTGNQGERYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNY
EEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCE
KTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLHYMPWATFRGGVRYQQGASWF
EEECEEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCHHHCCCEEECCCCCCC
GAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEECCCCCCCCCHHHHHHHHHEECCCC
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCCEEEHH
RLAGAVVGTRGNYHAFGYDFNVGVPITKPAEFDADPLVFGFTLTWQY
HHCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]