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The map label for this gene is hpmA [H]

Identifier: 170022346

GI number: 170022346

Start: 98170

End: 99561

Strand: Direct

Name: hpmA [H]

Synonym: YPK_0085

Alternate gene names: 170022346

Gene position: 98170-99561 (Clockwise)

Preceding gene: 170022345

Following gene: 170022347

Centisome position: 2.09

GC content: 38.43

Gene sequence:

>1392_bases
ATGAAGTTGACATATATTAAAACGAAACAGGGGTTGTCTATATTACCTCTCTCTATCATATTGTCGCTCTATGGGAGCTC
GGTTGCTTATGCTGATAATATTATTCCTGATATACAGGCCCCAGCGGGACAGCAAGCGGAAGTCTCTATTATAGAAACAC
CGCCCAGTACATGCCGAGCGCTTACCTCTTACTGTATCGGTATGACAGAGACTGTCGTTAATATTCAAGCGCCTGATGAA
AATGGGTTATCACATAACAAGTATTCTAAATTTGATGTGGTCGCTAATGGCTTGTTCGATGTCACGACACTCAATAATCG
CTTAGCTCAAGAGGTTAATGGCAACTCTTTTTTACAAGATAAATCGGCAACCATTATATTAAATGAAGTCAACTCATCAC
ATGCCAGTCTATTAGATGGGAATCTCCGTGTTGACGGGGGAAATGCGCATATTATTATTGCCAATCCAGCAGGTATTAAT
TGTCGAGGGTGCTCTTTTACTAATGCCTCTCATGTGACATTGACGACAGGTACGCCATCTTTTTCTGATAATAAACTAAA
CAGTTTTATTGTTGAGCAGGGAAATATCAATATTGAAAAAAATCCCTCTTACTATATGAGAACAGGTTTACGGTATAAGG
GGGCAGACAAGACTTATCTTGATCTATTCGCAGACACTATTACGGTTAGTGGTGAGATCAATGCGGACGATGGCTATATT
GTCACGGGAAAAAATAAAGTGGGTTTCTCTTTGCCTGGGCAACCATTGCAAGTGTCGCGTTTAGGCAATGAAAATACACC
AGTACCAGGTACGGTTAGTTTGGATGTCAGCGAAATTGGGGGAATGTACACCAATAAAATTCGTATCCATGCAACCGATG
GCACGATTAAAAATAAGGGGGCAATACGCGCGAACGATACACTAAGCCTCAGTTCTGCAGCCAATATAGATAACAGTAAT
GGGAATATATCAGGGAAAATGGTGTTACTGAGTAGCGAGGGTGTTATAAATAACTCTGGTGGCACAATATTAAATAATGG
TGAGTATGATTTATTACCTTCTCAAGGTATTAAAATAACATCTCGTGGCTTAAATAATGAAGGTGGAAAAATAGAGTATA
AAAATGGTAGCGTTGAAATAGCGACAGTTAACACCATCAAAAATGGTAAGGGTACAATTAAAGCAACATCAACGCAAGGG
CGGGTAAGAATAAAACTTCATAGTAATAACCTTAATAATACTGGAGGGAGTATTATTTCTTCAGGGAAAATAGAGGGTAA
AGTTAATAACATACGAAACAATAGAGGGGCTATTATTGGGTTAGGTGGAGTGGATTTGAATGAAACTGTTTTAATTAATG
ATACCGGTAAAATAATTTCTGATTTTAATTAA

Upstream 100 bases:

>100_bases
TTGTTGACTTTGTTTTATGAAAAACCGGTAATGATATCGGTTTTAGACCGTGTTATTCAAAACATAACAAACACATTGAT
TATTTAATAAGGGAAATAAT

Downstream 100 bases:

>100_bases
TTTCTTTGTAAGTGAGAGATGATTTTTTATTTAAAGTTAGTTGCTTTCGTGGCTAACTTTTATTGATTTTGTATTAATCA
TGTTTTGATTGAAATGGAGT

Product: filamentous hemagglutinin outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRALTSYCIGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQDKSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGIN
CRGCSFTNASHVTLTTGTPSFSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVRIKLHSNNLNNTGGSIISSGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN

Sequences:

>Translated_463_residues
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRALTSYCIGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQDKSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGIN
CRGCSFTNASHVTLTTGTPSFSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVRIKLHSNNLNNTGGSIISSGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN
>Mature_463_residues
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRALTSYCIGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQDKSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGIN
CRGCSFTNASHVTLTTGTPSFSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVRIKLHSNNLNNTGGSIISSGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN

Specific function: Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane. HpmA requires hpmB function [H]

COG id: COG3210

COG function: function code U; Large exoproteins involved in heme utilization or adhesion

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008638
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011102 [H]

Pfam domain/function: PF05860 Haemagg_act [H]

EC number: NA

Molecular weight: Translated: 49055; Mature: 49055

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRA
CEEEEEECCCCCEEEHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHH
LTSYCIGMTETVVNIQAPDENGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQD
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEECCHHHHHHCCCCCEEEC
KSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGINCRGCSFTNASHVTLTTGTPS
CCCEEEEEECCCCCCEEECCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
FSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
CCCCCCEEEEEECCCEEEECCCCEEEECCCEECCCCCCEEEEEEEEEEEEEEEECCCCEE
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKG
EECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCCEEEEEEEEEECCCCCCCCC
AIRANDTLSLSSAANIDNSNGNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKIT
CEEECCEEEECCCCCCCCCCCCEEEEEEEEECCCEEECCCCEEEECCCEEECCCCCCEEE
SRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQGRVRIKLHSNNLNNTGGSIIS
ECCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCCCEEE
SGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN
CCEEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCEEECCC
>Mature Secondary Structure
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRA
CEEEEEECCCCCEEEHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHH
LTSYCIGMTETVVNIQAPDENGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQD
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEECCHHHHHHCCCCCEEEC
KSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGINCRGCSFTNASHVTLTTGTPS
CCCEEEEEECCCCCCEEECCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
FSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
CCCCCCEEEEEECCCEEEECCCCEEEECCCEECCCCCCEEEEEEEEEEEEEEEECCCCEE
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKG
EECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCCEEEEEEEEEECCCCCCCCC
AIRANDTLSLSSAANIDNSNGNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKIT
CEEECCEEEECCCCCCCCCCCCEEEEEEEEECCCEEECCCCEEEECCCEEECCCCCCEEE
SRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQGRVRIKLHSNNLNNTGGSIIS
ECCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCCCEEE
SGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN
CCEEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]