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The map label for this gene is copY [H]

Identifier: 169834494

GI number: 169834494

Start: 759761

End: 760156

Strand: Direct

Name: copY [H]

Synonym: SPH_0814

Alternate gene names: 169834494

Gene position: 759761-760156 (Clockwise)

Preceding gene: 169833541

Following gene: 169832931

Centisome position: 33.83

GC content: 40.66

Gene sequence:

>396_bases
ATGCAGATTTCAGATGCAGAATGGCAGGTCATGAAGATTATTTGGATGCAGGGGGAGCAGACCAGTACAGATTTGATTAG
GGTTTTGGCAGAGCGGTTCGACTGGTCCAAGTCAACCATTCAAACTCTTTTGGCTCGTTTGGTTGAGAAAGAGTGTCTGA
CTCGGAAAAAAGAAGGCAAGTTCTTTGTTTATTCAGCCCTTTTAACTCTAGACCAAAGTCGGGATTTACTTGTCCAAGAT
ATCAAAGACAAGGTTTGTTCCCGTAGGATTAGGAATTTGTTGGCTGACTTGATTGTAGAATGTGAATTTACTCAGACTGA
CTTGGAAGACTTGGAAGCTGTGATTTCAGAGAAGAAATCAAGTGCTGTAACAGAAGTAAGATGTAATTGTATGTAA

Upstream 100 bases:

>100_bases
TATTTTTCGAAGAAAATATTATTTCTATAATTGACAAATGTAGATTTTAAGAGTATACTGATGAGTGTAATTGACAAATG
TAGATTTTGGAGGTATGGTA

Downstream 100 bases:

>100_bases
AGGAGACGTCATGTTAAATAGTATTGTAACCATTATTTGTATTGCCCTTATCGCGTTTATCTTGTTTTGGTTTTTCAAAA
AGCCTGAAAAATCTGGACAA

Product: CopY/TcrY family copper transport repressor

Products: NA

Alternate protein names: CopAB ATPases metal-fist type repressor [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLLARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQD
IKDKVCSRRIRNLLADLIVECEFTQTDLEDLEAVISEKKSSAVTEVRCNCM

Sequences:

>Translated_131_residues
MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLLARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQD
IKDKVCSRRIRNLLADLIVECEFTQTDLEDLEAVISEKKSSAVTEVRCNCM
>Mature_131_residues
MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLLARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQD
IKDKVCSRRIRNLLADLIVECEFTQTDLEDLEAVISEKKSSAVTEVRCNCM

Specific function: Acts as a copper responsive repressor. Binds to DNA in complex with Zn(2+), repressing the transcription of the copYZAB operon. Exchange of the bound zinc by two copper ions delivered by CopZ Cu(1+)-bound form causes release of CopY from the promoter, lea

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014071
- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 15223; Mature: 15223

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLLARLVEKECLTRKKEGK
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
FFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECEFTQTDLEDLEAVISEKKS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SAVTEVRCNCM
HHHHHHHHCCC
>Mature Secondary Structure
MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLLARLVEKECLTRKKEGK
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
FFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECEFTQTDLEDLEAVISEKKS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SAVTEVRCNCM
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7876197 [H]