Click here to switch to the map view.

The map label for this gene is yqhT [H]

Identifier: 169834257

GI number: 169834257

Start: 269787

End: 270848

Strand: Direct

Name: yqhT [H]

Synonym: SPH_0306

Alternate gene names: 169834257

Gene position: 269787-270848 (Clockwise)

Preceding gene: 169833621

Following gene: 169832429

Centisome position: 12.01

GC content: 43.69

Gene sequence:

>1062_bases
ATGAATAAACGCGTACAAGCATTTCTAGCTAAAATGCAAGAAAAAGAACTAGATGGTATCATCATCAACAATCTTAAAAA
CGTCTATTATTTGACTGGTTTTTGGGGCTCAAACGGAACAGTCTTTATCAGCCGTGACCGTCAGGTCTTAGTGACAGACT
CTCGCTATATCATCGCAGCTAAGCAAGAAACCAGTGGTTTTGAGATTGTGGCTGATCGTGATGAATTGGCTGTCATTGCA
GGAATTGTTAAGGACATGGGCTTGACTCGTATCGGTTTTGAAGATGAGATTTCAGTGTCTTATTACCACCGTATGCAGGC
AGCTTTTGCAGGTTTGGACTTGCTTCCACAAACTCAGTTTGTGGAAGGTCTTCGTATGATTAAGGATGAGGCAGAGATTG
CAGCGATTTGCAAGGCTTGTTCTATCTCAGACCAAGCTTTCCGCGATGCGCTTGACTTTATCAAACCAGGAAAAACTGAA
ATTGAGATTGCCAACTTCCTTGATTTCCGCATGCGTGAGTTGGGAGCATCTGGCTTATCTTTTGATACGATCCTAGCTAG
CGGTATCAATTCTTCTAAACCCCATGCCCATCCAATGCACAAACCAGTGGAGTTGGGAGAAGCCATTACCATGGACTTCG
GCTGTCTCTATGACCACTATGTCAGTGATATGACCCGGACTATCTATCTAGGGCATGTTAGCGATGAGCAGGCAGAGATT
TACAATACGGTTCTAAAAGCTAACCAAGCCTTGATTGACCAAGCTAAGGCAGGCTTAGGTTTCCGTGACTTTGACAAAAT
CCCTCGTGATATTATCATTGAGGCAGGTTATGGCGACTACTTTACTCACGGCATTGGGCACGGTATTGGTCTGGATATCC
ATGAGGAACCCTACTTTAGCCAGACTTCTACAGAAACTATTAAAGCAGGTATGGCCTTGACCGATGAACCAGGTATCTAT
ATCGAAGGCAAATATGGCGTCCGTATCGAGGATGATATCCTGATTACAGAGACAGGTTGTGAATTATTGACCCTAGCTCC
AAAAGAGTTGATAGTCATTTAG

Upstream 100 bases:

>100_bases
GGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGACACTA
TTTGAAAGGAAAGTTACATC

Downstream 100 bases:

>100_bases
TTGTTTGTCAAGAAAAAAGTACGAAAATGACGAAAAAAGTCAAAAAAAATTAAAAATAGGTCGCAAGTCGGATGTTTTTT
ATGGTATAATAGACTAAACT

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIA
GIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAICKACSISDQAFRDALDFIKPGKTE
IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKAGMALTDEPGIY
IEGKYGVRIEDDILITETGCELLTLAPKELIVI

Sequences:

>Translated_353_residues
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIA
GIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAICKACSISDQAFRDALDFIKPGKTE
IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKAGMALTDEPGIY
IEGKYGVRIEDDILITETGCELLTLAPKELIVI
>Mature_353_residues
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIA
GIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAICKACSISDQAFRDALDFIKPGKTE
IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKAGMALTDEPGIY
IEGKYGVRIEDDILITETGCELLTLAPKELIVI

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=264, Percent_Identity=29.5454545454545, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI93141226, Length=178, Percent_Identity=35.3932584269663, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI264681563, Length=216, Percent_Identity=32.4074074074074, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI260593665, Length=287, Percent_Identity=25.4355400696864, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI149589008, Length=287, Percent_Identity=25.4355400696864, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI264681565, Length=213, Percent_Identity=30.5164319248826, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI260593663, Length=233, Percent_Identity=26.1802575107296, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI164420681, Length=273, Percent_Identity=24.9084249084249, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788728, Length=350, Percent_Identity=38, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1789275, Length=252, Percent_Identity=30.1587301587302, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790282, Length=292, Percent_Identity=25.3424657534247, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17508215, Length=291, Percent_Identity=29.553264604811, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71989583, Length=266, Percent_Identity=24.812030075188, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=233, Percent_Identity=29.1845493562232, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321118, Length=279, Percent_Identity=26.1648745519713, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322999, Length=201, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320922, Length=273, Percent_Identity=27.1062271062271, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357079, Length=288, Percent_Identity=30.5555555555556, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19920384, Length=270, Percent_Identity=29.2592592592593, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17137632, Length=363, Percent_Identity=25.068870523416, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39259; Mature: 39259

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAA
CCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCEEEEECCCEEEEECCEEEEEE
KQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQF
ECCCCCEEEEECCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VEGLRMIKDEAEIAAICKACSISDQAFRDALDFIKPGKTEIEIANFLDFRMRELGASGLS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCC
FDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
HHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHHHCCEEEEEEEECCCHHHHH
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFS
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCC
QTSTETIKAGMALTDEPGIYIEGKYGVRIEDDILITETGCELLTLAPKELIVI
CCCHHHHHCCCEEECCCCEEEECCCCCEEECCEEEEECCCCEEEECCCEEEEC
>Mature Secondary Structure
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAA
CCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCEEEEECCCEEEEECCEEEEEE
KQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQF
ECCCCCEEEEECCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VEGLRMIKDEAEIAAICKACSISDQAFRDALDFIKPGKTEIEIANFLDFRMRELGASGLS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCC
FDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
HHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHHHCCEEEEEEEECCCHHHHH
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFS
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCC
QTSTETIKAGMALTDEPGIYIEGKYGVRIEDDILITETGCELLTLAPKELIVI
CCCHHHHHCCCEEECCCCEEEECCCCCEEECCEEEEECCCCEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]