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The map label for this gene is exp5 [H]

Identifier: 169833942

GI number: 169833942

Start: 795481

End: 797661

Strand: Direct

Name: exp5 [H]

Synonym: SPH_0859

Alternate gene names: 169833942

Gene position: 795481-797661 (Clockwise)

Preceding gene: 169833307

Following gene: 169834285

Centisome position: 35.42

GC content: 41.27

Gene sequence:

>2181_bases
ATGATGAAAGATACATTCAAAAATGTCTTGTCTTTCGAATTTTGGCAAAAATTCGGTAAGGCTTTGATGGTAGTTATCGC
GGTTATGCCGGCTGCTGGTTTGATGATTTCAATCGGTAAGTCTATCGTGATGATTAACCCAACCTTTACACCACTTGTCA
TCACAGGTGGAATTCTTGAGCAAATCGGTTGGGGGGTTATCGGTAACCTTCACATTTTGTTTGCCCTAGCCATTGGAGGA
AGCTGGGCTAAAGAACGTGCTGGTGGTGCTTTCGCCGCTGGTCTTGCCTTCATCTTGATTAACCGTATCACTGGTACAAT
CTTTGGTGTATCAGGCGATATGTTGAAAAATCCAGATGCTATGGTAACTACTTTCTTTGGTGGTTCAATCAAAGTTGCTG
ATTACTTTATCAGTGTTCTTGAAGCTCCAGCCTTGAACATGGGGGTATTCGTAGGGATTATCTCAGGTTTTGTAGGGGCA
ACTGCTTACAACAAATACTACAACTTCCGTAAACTTCCTGATGCACTTTCATTCTTCAACGGGAAACGTTTCGTACCATT
TGTAGTTATTCTTCGTTCAGCAATCGCTGCAATTCTACTTGCTGCTTTCTGGCCAGTAGTTCAAACAGGTATCAATAACT
TCGGTATCTGGATTGCCAACTCACAAGAAACTGCTCCAATTCTTGCACCATTCTTGTATGGTACTTTGGAACGTTTGCTC
TTGCCATTTGGTCTTCACCACATGTTGACTATCCCAATGAACTACACAGCTCTTGGTGGTACTTATGACATTTTAACTGG
TGCAGCTAAAGGTACTCAAGTATTCGGTCAAGACCCACTATGGCTTGCATGGGTAACAGACCTTGTAAACCTTAAAGGTA
CTGATGCTAGTCAATATCAACACTTGTTAGATACAGTACATCCAGCTCGTTTCAAAGTTGGACAAATGATCGGTTCATTC
GGTATCTTGATGGGTGTGATTGTTGCTATCTACCGTAATGTTGATGCTGACAAGAAACATAAATACAAAGGTATGATGAT
TGCAACAGCTCTTGCAACATTCTTGACAGGGGTTACTGAACCAATCGAATACATGTTCATGTTCATCGCAACACCTATGT
ATCTTGTTTACTCACTTGTTCAAGGTGCTGCCTTCGCTATGGCTGACGTCGTAAACCTACGTATGCACTCATTCGGTTCA
ATCGAGTTCTTGACTCGTACACCTATTGCAATCAGTGCTGGTATTGGTATGGATATCGTTAACTTCGTTTGGGTAACTGT
TCTCTTTGCTGTAATCATGTACTTTATCGCAAACTTCATGATTCAAAAATTCAACTACGCAACTCCAGGGCGCAACGGAA
ACTACGAAACTGCTGAAGGTTCAGAAGAAACCAGCAGTGAAGTGAAAGTTGCAGCAGGCTCTCAAGCTGTAAACATTATC
AACCTTCTTGGTGGACGTGTAAACATCGTTGATGTTGACGCATGTATGACTCGTCTTCGTGTAACTGTTAAAGATGCAGA
TAAAGTAGGAAATGCAGAGCAATGGAAAGCAGAAGGAGCTATGGGTCTTGTCATGAAAGGACAAGGGGTTCAAGCTATCT
ACGGTCCAAAAGCTGACATTTTGAAATCTGATATCCAAGATATCCTTGATTCAGGTGAAATCATTCCTGAAACTCTTCCA
AGCCAAATGACTGAAGCACAACAAAACACTGTTCACTTCAAAGATCTTACTGAGGAAGTTTACTCAGTAGCAGACGGTCA
AGTTGTTGCTTTGGAACAAGTAAAGGATCCAGTATTTGCTCAAAAAATGATGGGTGATGGATTTGCAGTAGAACCTGCAA
ATGGAAACATTGTATCTCCAGTTTCAGGTACTGTATCAAGCATCTTCCCAACAAAACATGCTTTTGGTATTGTGACGGAA
GCAGGTCTTGAAGTATTGGTTCACATTGGTTTGGACACAGTAAGTCTTGAAGGTAAACCATTTACAGTTCATGTTGCTGA
AGGACAAAAAGTTACAGCAGGAGATCTCCTTGTCACAGCTGACTTGGATGCTATCCGTGCAGCAGGACGTGAAACTTCAA
CAGTAGTTGTCTTCACAAATGGTGATGCAATTAAATCAGTTAAATTAGAAAAAACAGGTTCTCTTGCAGCTAAAACAGCA
GTTGCTAAAGTAGAATTGTAA

Upstream 100 bases:

>100_bases
AAAAGCCTTTACAAAAAAAATTAAAGTGGTATAATTAAATCATAGAAAGTGCAAACGTTTTCGTAAAACGTTTGCCTAAA
TAAAAATAAAGGAGATTTGA

Downstream 100 bases:

>100_bases
TATACTTGAGGTTGGAAGCTGTATTCCAACCTCTTATTTTGGGAGAAAAGAATGAAATTTTTAACACTCAATACTCACAG
TTTGATGGAGAAAGAAGCAG

Product: pts system, IIBC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVMINPTFTPLVITGGILEQIGWGVIGNLHILFALAIGG
SWAKERAGGAFAAGLAFILINRITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWIANSQETAPILAPFLYGTLERLL
LPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFGQDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSF
GILMGVIVAIYRNVDADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVNLRMHSFGS
IEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPGRNGNYETAEGSEETSSEVKVAAGSQAVNII
NLLGGRVNIVDVDACMTRLRVTVKDADKVGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLP
SQMTEAQQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGTVSSIFPTKHAFGIVTE
AGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADLDAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTA
VAKVEL

Sequences:

>Translated_726_residues
MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVMINPTFTPLVITGGILEQIGWGVIGNLHILFALAIGG
SWAKERAGGAFAAGLAFILINRITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWIANSQETAPILAPFLYGTLERLL
LPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFGQDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSF
GILMGVIVAIYRNVDADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVNLRMHSFGS
IEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPGRNGNYETAEGSEETSSEVKVAAGSQAVNII
NLLGGRVNIVDVDACMTRLRVTVKDADKVGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLP
SQMTEAQQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGTVSSIFPTKHAFGIVTE
AGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADLDAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTA
VAKVEL
>Mature_726_residues
MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVMINPTFTPLVITGGILEQIGWGVIGNLHILFALAIGG
SWAKERAGGAFAAGLAFILINRITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWIANSQETAPILAPFLYGTLERLL
LPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFGQDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSF
GILMGVIVAIYRNVDADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVNLRMHSFGS
IEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPGRNGNYETAEGSEETSSEVKVAAGSQAVNII
NLLGGRVNIVDVDACMTRLRVTVKDADKVGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLP
SQMTEAQQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGTVSSIFPTKHAFGIVTE
AGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADLDAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTA
VAKVEL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=734, Percent_Identity=31.7438692098093, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1787343, Length=556, Percent_Identity=30.5755395683453, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1787908, Length=565, Percent_Identity=28.4955752212389, Blast_Score=213, Evalue=5e-56,
Organism=Escherichia coli, GI1790159, Length=138, Percent_Identity=41.304347826087, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788757, Length=129, Percent_Identity=41.8604651162791, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011300 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 78056; Mature: 78056

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVMINPTFTPLVITGGILE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCCCEEECHHHH
QIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINRITGTIFGVSGDMLKNPDA
HHCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
MVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGATAYNKYYNFRKLPDALSFFN
EEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHC
GKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWIANSQETAPILAPFLYGTLERLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
LPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFGQDPLWLAWVTDLVNLKGTDASQYQ
HHHCCHHEEEECCCEEECCCCHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCCHHHHH
HLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNVDADKKHKYKGMMIATALATFLTGVTE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCH
PIEYMFMFIATPMYLVYSLVQGAAFAMADVVNLRMHSFGSIEFLTRTPIAISAGIGMDIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHH
NFVWVTVLFAVIMYFIANFMIQKFNYATPGRNGNYETAEGSEETSSEVKVAAGSQAVNII
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHH
NLLGGRVNIVDVDACMTRLRVTVKDADKVGNAEQWKAEGAMGLVMKGQGVQAIYGPKADI
HHCCCEEEEEEHHHHHHHHEEEEECHHCCCCCHHHHCCCCEEEEEECCCCEEEECCCHHH
LKSDIQDILDSGEIIPETLPSQMTEAQQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHCCHHHH
QKMMGDGFAVEPANGNIVSPVSGTVSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKP
HHHCCCCEEEECCCCCEECCCCCCHHHHCCCHHHHHHHHHHHHHEEEEECCCEEEECCCE
FTVHVAEGQKVTAGDLLVTADLDAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTA
EEEEECCCCEEECCCEEEEECHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHH
VAKVEL
HHEECC
>Mature Secondary Structure
MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVMINPTFTPLVITGGILE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCCCEEECHHHH
QIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINRITGTIFGVSGDMLKNPDA
HHCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
MVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGATAYNKYYNFRKLPDALSFFN
EEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHC
GKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWIANSQETAPILAPFLYGTLERLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
LPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFGQDPLWLAWVTDLVNLKGTDASQYQ
HHHCCHHEEEECCCEEECCCCHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCCHHHHH
HLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNVDADKKHKYKGMMIATALATFLTGVTE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCH
PIEYMFMFIATPMYLVYSLVQGAAFAMADVVNLRMHSFGSIEFLTRTPIAISAGIGMDIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHH
NFVWVTVLFAVIMYFIANFMIQKFNYATPGRNGNYETAEGSEETSSEVKVAAGSQAVNII
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHH
NLLGGRVNIVDVDACMTRLRVTVKDADKVGNAEQWKAEGAMGLVMKGQGVQAIYGPKADI
HHCCCEEEEEEHHHHHHHHEEEEECHHCCCCCHHHHCCCCEEEEEECCCCEEEECCCHHH
LKSDIQDILDSGEIIPETLPSQMTEAQQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHCCHHHH
QKMMGDGFAVEPANGNIVSPVSGTVSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKP
HHHCCCCEEEECCCCCEECCCCCCHHHHCCCHHHHHHHHHHHHHEEEEECCCEEEECCCE
FTVHVAEGQKVTAGDLLVTADLDAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTA
EEEEECCCCEEECCCEEEEECHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHH
VAKVEL
HHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916; 7934910 [H]