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The map label for this gene is ftsX [H]

Identifier: 169833307

GI number: 169833307

Start: 794269

End: 795195

Strand: Direct

Name: ftsX [H]

Synonym: SPH_0858

Alternate gene names: 169833307

Gene position: 794269-795195 (Clockwise)

Preceding gene: 169833016

Following gene: 169833942

Centisome position: 35.37

GC content: 36.79

Gene sequence:

>927_bases
ATGATTAGTAGATTTTTTCGCCATTTATTTGAAGCCTTAAAAAGTTTGAAACGAAATGGTTGGATGACAGTAGCTGCTGT
CAGTTCAGTCATGATTACTTTGACCTTGGTGGCAATATTTGCATCTGTTATTTTCAATACAGCGAAACTAGCTACAGATA
TTGAAAATAATGTCCGTGTAGTAGTTTATATCCGAAAGGATGTGGAAGATAATAGTCAGACAATTGAAAAAGAAGGTCAA
ACTGTTACAAATAATGACTACCACAAGGTATATGATTCTTTGAAGAACATGTCTACGGTTAAAAGTGTTACCTTTTCAAG
TAAAGAAGAACAATATGAAAAATTAACCGAGATAATGGGAGATAACTGGAAAATCTTTGAAGGAGATGCCAATCCTCTCT
ATGATGCCTATATTGTAGAGGCAAACACTCCAAATGATGTAAAAACTATAGCCGAAGATGCTAAAAAAATTGAAGGTGTC
TCTGAGGTTCAAGATGGCGGTGCCAATACAGAAAGACTCTTCAAGTTAGCTTCATTTATCCGTGTTTGGGGACTAGGGAT
TGCTGCTTTGTTAATTTTTATCGCAGTTTTCTTGATTTCAAATACCATTCGTATTACCATTATTTCCCGCAGTCGCGAAA
TTCAAATCATGCGCTTGGTCGGAGCTAAAAACAGTTATATCCGTGGACCGTTCTTGTTAGAAGGAGCCTTTATCGGTTTA
TTGGGAGCTATCGCACCATCTGTTTTGGTCTTTATTGTTTATCAAATTGTTTACCAATCTGTCAACAAATCGTTGGTAGG
GCAAAATCTATCCATGATTAGTCCAGATTTATTTAGTCCGTTGATGATTGCCCTACTATTTGTGATTGGGGTTTTCATTG
GTTCATTGGGATCAGGAATATCCATGCGCCGATTCTTGAAGGTTTAG

Upstream 100 bases:

>100_bases
ACTCATAATAGCCAGATTGTAAATACCTTGCGCCACCGTGTCATTGCCATTGAAAATGGCCGTGTCGTTCGTGACGAATC
AAAAGGAGAGTATGGATACG

Downstream 100 bases:

>100_bases
GTAAAATAGCTGCTTTTATGAGGAGATTGTAAAATCTCCTTTTTTGCTACAAGAGTTTTTGAAAAGAGATGCGTAGAAGA
AAAGAGCTTCCAAAGAAGTC

Product: cell division ABC transporter, permease protein FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQ
TVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGL
LGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGISMRRFLKV

Sequences:

>Translated_308_residues
MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQ
TVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGL
LGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGISMRRFLKV
>Mature_308_residues
MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQ
TVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGL
LGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGISMRRFLKV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=247, Percent_Identity=25.1012145748988, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 34287; Mature: 34287

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRV
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMG
EEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
DNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGVSEVQDGGANTERLFKLASFI
CCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHH
RVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGL
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
LGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCH
SMRRFLKV
HHHHHHCC
>Mature Secondary Structure
MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRV
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMG
EEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
DNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGVSEVQDGGANTERLFKLASFI
CCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHH
RVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGL
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
LGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCH
SMRRFLKV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]