Click here to switch to the map view.

The map label for this gene is cpsD [H]

Identifier: 169833689

GI number: 169833689

Start: 407790

End: 408479

Strand: Direct

Name: cpsD [H]

Synonym: SPH_0458

Alternate gene names: 169833689

Gene position: 407790-408479 (Clockwise)

Preceding gene: 169833763

Following gene: 169832835

Centisome position: 18.16

GC content: 41.01

Gene sequence:

>690_bases
ATGCCAACGTTAGAAATCTCACAGGCGAAATTAGAACTTGTGAAAAAGGCAGAGGAATATTATAATGCTTTGTGCACGAA
CCTACAGTTAAGTGGAGATGATTTGAAAGTATTTTCTATCACTTCTGTGAAAGCAGGAGAAGGAAAAACAACGACTTCCA
CCAATATCGCTTGGGCTTTTGCGCGTGCAGGTTACAAAACGCTTCTGATTGATGCAGACATGCGTAACTCCGTTATGTCA
GGTGTCTTTAAATCAAGGGAAAGGATTACTGGACTAACAGAATTTCTATCAGGGACAACAGACCTGTCACAGGGGCTTTG
CGATACCAATATTGAGAATCTCTTTGTGATTCAGGCTGGCTCTGTGTCACCAAATCCGACAGCCCTTCTTCAAAGTAAGA
ATTTCAGTACAATGCTTGAAACCTTGCGTAAATATTTTGACTATATCGTCGTAGACACTGCCCCTGTCGGTGTCGTGATT
GATGCGGCTATCATTATGCAGAAATGTGATGCTTCTATTTTAGTGACGAAGGCAGGTGAAACAAAACGACGGGATCTTCA
AAAAGCGAAAGAACAGTTGGAACAAACTGGGAAGTCGTGTTTAGGAGTTGTGTTGAATAAACTCGATACTTCAGTAGAGA
AATACGGTTCTTATGGGAGTTATGGGAATTACAGGAAACAGAAAAAATAG

Upstream 100 bases:

>100_bases
CGATACCCGTGTAAAACGTCCTGAAGATGTTGAAGATGTACTGCAAATGCCACTTCTAGGAGTCGTTCCAGATTTTGATA
AAATGAAATAGGAGGAAGTT

Downstream 100 bases:

>100_bases
GTTGAGGGATAGAAATGAGTGAAAAACTAGCAAAGCCTTCAGTAGCCATAGTCCAGAGTTTTCTTGTTATTTTATTGACT
TATCTACTTAGCGCTGTGAG

Product: tyrosine-protein kinase CpsD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMS
GVFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVI
DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSYGSYGNYRKQKK

Sequences:

>Translated_229_residues
MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMS
GVFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVI
DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSYGSYGNYRKQKK
>Mature_228_residues
PTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSG
VFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVID
AAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSYGSYGNYRKQKK

Specific function: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell sur

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Inner membrane (Probable) [C]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CpsD/CapB family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=185, Percent_Identity=29.7297297297297, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787216, Length=193, Percent_Identity=31.6062176165803, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 25142; Mature: 25011

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAF
CCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEEEEEECCCCCCCCCCHHHHHH
ARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAG
HHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEEC
SVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVIDAAIIMQKCDASILVTKAGE
CCCCCCCEEEECCCHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCC
TKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSYGSYGNYRKQKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAF
CCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEEEEEECCCCCCCCCCHHHHHH
ARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAG
HHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEEC
SVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVIDAAIIMQKCDASILVTKAGE
CCCCCCCEEEECCCHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCC
TKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSYGSYGNYRKQKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11179285; 11463916 [H]