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The map label for this gene is cpsE [H]

Identifier: 169832835

GI number: 169832835

Start: 408494

End: 409855

Strand: Direct

Name: cpsE [H]

Synonym: SPH_0459

Alternate gene names: 169832835

Gene position: 408494-409855 (Clockwise)

Preceding gene: 169833689

Following gene: 169834388

Centisome position: 18.19

GC content: 37.74

Gene sequence:

>1362_bases
ATGAGTGAAAAACTAGCAAAGCCTTCAGTAGCCATAGTCCAGAGTTTTCTTGTTATTTTATTGACTTATCTACTTAGCGC
TGTGAGAGAAACAGAGATTGTTTCAACAACAGCTATTGTACTTTATATCCTCCACTATTTTGTCTTTTATATCAGTGATT
ATGGACGGAATTTCTTTAAAAGGGGATATTTGATTGAACTTGTCCAGACATTGAAATATATCCTATTCTTTGCGCTAGCG
ATTAGTATTTCTAATTTTTTCTTAGAAGATCGATTTAGTATTTCCAGAAGAGGCATGATTTACTTCCTCTTATTACATGT
TTTCTTAGTCTATGTGCTAAACCCATTTATCAAGTGGTATTGGAAGCGGGCTTATCCCAACTTTAAAGGAAGTAAGAAGA
TTCTCCTACTTACAGCAACTTCTCGTGTTGAAAAGGTACTGGATAGACTAATAGAATCATATGATGTTGTTGGGGAGTTG
GTAGCCGTCAGTGTTTTAGATAAACCAGATTTTCAGCATGATGATTTAAAGGTTGTAGCAGAGGGGGAGATAGTAAATTT
TGCGACTCATGAGGTGGTCGATGAAGTCTTTATCAATCTTCCAAGTGAAAAATACAATATTGGAGAGCTTGTCTCTCAGT
TTGAAACGATGGGAATTGATGTAACAGTCAATCTAAATGCTTTCGATTGGGCACGTAACAAGCAAATTTGTGAGATGGCA
GGACTAAATGTTGTGACTTTTTCTACAACATTTTATAAGACTAGCCATGTGATTGCTAAGCGGATTATTGATATTGTCGG
TTCCCTGGTAGGTTTGATATTATGTGGTCTAGTCAGTATTGTGCTGGTTCCTTTGATTCGAAAGGATGGGGGTTCTGCTT
TTTTTGCTCAGACGCGTATAGGAAAAAATGGCCGCCATTTTACTTTTTATAAGTTTCGCTCTATGTGTGTGGATGCTGAG
GAGAAAAAAAGAGAACTCATGGAACAAAATACCATGCAGGGTGGAATGTTTAAGGTGGACGATGATCCTCGTATCACGAA
AATTGGTCATTTTATACGGAAGACGAGCTTGGACGAGCTACCACAGTTTTATAATGTTCTAAAGGGAGATATGAGTTTGG
TAGGTACACGACCACCAACAGTGGACGAGTATGAGCACTATACCCCAGAACAAAAACGTCGCCTAAGTTTTAAACCTGGC
ATAACAGGTTTATGGCAGGTCAGCGGACGAAGTGAAATCAAAAATTTCGATGAAGTTGTCAAATTAGATGTGGCCTATAT
TGATGGTTGGACAATCTGGAAAGATATTGAAATTTTATTGAAGACAGTTAAGGTTGTATTGATGAAGGATGGAGCGAAAT
AG

Upstream 100 bases:

>100_bases
GAGTTGTGTTGAATAAACTCGATACTTCAGTAGAGAAATACGGTTCTTATGGGAGTTATGGGAATTACAGGAAACAGAAA
AAATAGGTTGAGGGATAGAA

Downstream 100 bases:

>100_bases
TTCATATGAATGAGAGAATTCAAATATTAGGAATTACTATAGATCCATTAACGATGAAAGAAACAGTGGATGCTGTTGAA
CAGTATGTTTTAAAGAAGCA

Product: galactosyl transferase CpsE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYILHYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALA
ISISNFFLEDRFSISRRGMIYFLLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESYDVVGEL
VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMGIDVTVNLNAFDWARNKQICEMA
GLNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCGLVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAE
EKKRELMEQNTMQGGMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQKRRLSFKPG
ITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKDGAK

Sequences:

>Translated_453_residues
MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYILHYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALA
ISISNFFLEDRFSISRRGMIYFLLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESYDVVGEL
VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMGIDVTVNLNAFDWARNKQICEMA
GLNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCGLVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAE
EKKRELMEQNTMQGGMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQKRRLSFKPG
ITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKDGAK
>Mature_452_residues
SEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYILHYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAI
SISNFFLEDRFSISRRGMIYFLLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESYDVVGELV
AVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMGIDVTVNLNAFDWARNKQICEMAG
LNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCGLVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAEE
KKRELMEQNTMQGGMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQKRRLSFKPGI
TGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKDGAK

Specific function: Galactosyl transferase is essential for the assembly of the group B streptococci (GBS) type III capsular polysaccharide. May be involved in the formation of either or both galactosidic bonds by catalyzing the addition of galactose to an oligosaccharide pr

COG id: COG2148

COG function: function code M; Sugar transferases involved in lipopolysaccharide synthesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial sugar transferase family [H]

Homologues:

Organism=Escherichia coli, GI1788360, Length=214, Percent_Identity=37.3831775700935, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003362
- InterPro:   IPR017475 [H]

Pfam domain/function: PF02397 Bac_transf [H]

EC number: NA

Molecular weight: Translated: 52022; Mature: 51891

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYILHYFVFYISDYGRNFFK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYFLLLHVFLVYVLNPFIKWY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
WKRAYPNFKGSKKILLLTATSRVEKVLDRLIESYDVVGELVAVSVLDKPDFQHDDLKVVA
HHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
EGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMGIDVTVNLNAFDWARNKQICEMA
CCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEECCHHCCCCCCHHHHHC
GLNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCGLVSIVLVPLIRKDGGSAFFAQTRI
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQGGMFKVDDDPRITKIGHFIRKTSLDEL
CCCCCEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCHHHH
PQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQKRRLSFKPGITGLWQVSGRSEIKNFDEVV
HHHHHHHHCCHHEECCCCCCCCCHHCCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHH
KLDVAYIDGWTIWKDIEILLKTVKVVLMKDGAK
HHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYILHYFVFYISDYGRNFFK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYFLLLHVFLVYVLNPFIKWY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
WKRAYPNFKGSKKILLLTATSRVEKVLDRLIESYDVVGELVAVSVLDKPDFQHDDLKVVA
HHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
EGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMGIDVTVNLNAFDWARNKQICEMA
CCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEECCHHCCCCCCHHHHHC
GLNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCGLVSIVLVPLIRKDGGSAFFAQTRI
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQGGMFKVDDDPRITKIGHFIRKTSLDEL
CCCCCEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCHHHH
PQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQKRRLSFKPGITGLWQVSGRSEIKNFDEVV
HHHHHHHHCCHHEECCCCCCCCCHHCCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHH
KLDVAYIDGWTIWKDIEILLKTVKVVLMKDGAK
HHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8355611; 10913080; 11773119; 12354221 [H]