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The map label for this gene is ygcA [C]

Identifier: 169824993

GI number: 169824993

Start: 1408220

End: 1409548

Strand: Direct

Name: ygcA [C]

Synonym: FMG_1296

Alternate gene names: 169824993

Gene position: 1408220-1409548 (Clockwise)

Preceding gene: 169824992

Following gene: 169824994

Centisome position: 78.34

GC content: 34.09

Gene sequence:

>1329_bases
ATGAAAAAAATTTTAGAGGCAAAAGTAGAATACAATGTATTTCCCAACAAGGGAATTTGCAAAATAGACGATAATTTGTA
TTCTATAAAGAACACAATTCAAGGACAAACAATCTCTTTTCAACGAAAAAGAAAGAAAAAGGGATTTATTGAGGGAAAAC
TAGTTGAAAAACTAGAAAAGTCTCCCCTTGAAACTATTGAAGGTTGTCCTGTAAATGAAAGATGCGGCGGTTGTATTTAT
CAAAAATTAGAGTACGATGTGGAGTGCGATTTGAAGAAAAAAACACTCACAGAATTGTACAAAGATATTTACGATGAGGA
TATTATTTTTCATCCATCGCCTATTTTACAAGGCTACAGAAACAAAATGGAATACACTTTTGGAGATAGTGTCAAAGGTG
GTCCACTTGTTTTGGGACTTCACACTAAAAACAAATTCTACGAAATAACAGACACTGTAGATTGCAATATCATTGATGAA
GGCTTCAACAAAATCAGACAAGCTGTTCAAGAATATTTTCGTGACAAAAATTACGAATTTTTCAAAAAAATAAAACATAC
TGGGCTTTTGAGACACTTCATAATCAGAAAAAGTTTCAGTGATGATGAGTACATGATTAATTTGGTAACGACAAGTGATA
AGTTTGATGTGAATGATTTCGTTGAATTTGCAAAGCAAATCGACAACAGAATCGTATCGATTTACCACACAATTAACGAT
AATATTTCAGACGCAGTAATAGTCGACAAATTAGAATTGTTGCATGGCAAAGAATATTTGACAGAAAAAATAAACGGCTT
GGAATTTAGGATATCTCCATTTTCCTTCTTCCAACCAAATCCGGCACAAGCAGAACAAATTTATACCAGAGCATTGGAAT
TGGCTGGAGATTTGTCAGGAAAAAACGTATATGATTTGTATTGTGGAACTGGAACCATCGCACAAATTTTCGCTAAAAAA
TCCGAAAGTGTGATTGGCGTCGAAATAGTAGAAGAAGCAGTCGAAAAAGCAAAAGAAAACGCAGAACTAAACGGATTGAC
TAACACAGAGTTCATCTGCGATGATTGCTTGAATTTTATGGAAAAAGTTGAGAAAAAAGACGTAGTAGTCTTGGATCCTC
CACGAGATGGAATTCATCCAAAAGCAATCGATAGATTAATCGACATCAATCCCGATAAATTCATCTACATTTCTTGCAAT
CCGATAACACAAAGAATGGATTTGGACAAATTTATCGAAAAAGGGTATGAAATTAAGTCATTAGAGTTTTTCGATCAGTT
CCCAAGGACTTACCACTGCGAAGCTGTTGTGCTTCTATCAAGAAAATAA

Upstream 100 bases:

>100_bases
ATGAACCTTGGCAAGTATTGGAATACGGACAATCAATCGGAGATATTCATGATATCGTCGTAGAAAATATGCAAAGACAA
GCAGACGGTCTACAAGGATA

Downstream 100 bases:

>100_bases
GAATATAGGATATTTTTACTTTATTTAGAAATTTGGAGGAAATAATGATAAAGAAAATAGGAGTTGTGAGCTTATCAAGT
GGTGTTTTGGGAGAAAGTTT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKKILEAKVEYNVFPNKGICKIDDNLYSIKNTIQGQTISFQRKRKKKGFIEGKLVEKLEKSPLETIEGCPVNERCGGCIY
QKLEYDVECDLKKKTLTELYKDIYDEDIIFHPSPILQGYRNKMEYTFGDSVKGGPLVLGLHTKNKFYEITDTVDCNIIDE
GFNKIRQAVQEYFRDKNYEFFKKIKHTGLLRHFIIRKSFSDDEYMINLVTTSDKFDVNDFVEFAKQIDNRIVSIYHTIND
NISDAVIVDKLELLHGKEYLTEKINGLEFRISPFSFFQPNPAQAEQIYTRALELAGDLSGKNVYDLYCGTGTIAQIFAKK
SESVIGVEIVEEAVEKAKENAELNGLTNTEFICDDCLNFMEKVEKKDVVVLDPPRDGIHPKAIDRLIDINPDKFIYISCN
PITQRMDLDKFIEKGYEIKSLEFFDQFPRTYHCEAVVLLSRK

Sequences:

>Translated_442_residues
MKKILEAKVEYNVFPNKGICKIDDNLYSIKNTIQGQTISFQRKRKKKGFIEGKLVEKLEKSPLETIEGCPVNERCGGCIY
QKLEYDVECDLKKKTLTELYKDIYDEDIIFHPSPILQGYRNKMEYTFGDSVKGGPLVLGLHTKNKFYEITDTVDCNIIDE
GFNKIRQAVQEYFRDKNYEFFKKIKHTGLLRHFIIRKSFSDDEYMINLVTTSDKFDVNDFVEFAKQIDNRIVSIYHTIND
NISDAVIVDKLELLHGKEYLTEKINGLEFRISPFSFFQPNPAQAEQIYTRALELAGDLSGKNVYDLYCGTGTIAQIFAKK
SESVIGVEIVEEAVEKAKENAELNGLTNTEFICDDCLNFMEKVEKKDVVVLDPPRDGIHPKAIDRLIDINPDKFIYISCN
PITQRMDLDKFIEKGYEIKSLEFFDQFPRTYHCEAVVLLSRK
>Mature_442_residues
MKKILEAKVEYNVFPNKGICKIDDNLYSIKNTIQGQTISFQRKRKKKGFIEGKLVEKLEKSPLETIEGCPVNERCGGCIY
QKLEYDVECDLKKKTLTELYKDIYDEDIIFHPSPILQGYRNKMEYTFGDSVKGGPLVLGLHTKNKFYEITDTVDCNIIDE
GFNKIRQAVQEYFRDKNYEFFKKIKHTGLLRHFIIRKSFSDDEYMINLVTTSDKFDVNDFVEFAKQIDNRIVSIYHTIND
NISDAVIVDKLELLHGKEYLTEKINGLEFRISPFSFFQPNPAQAEQIYTRALELAGDLSGKNVYDLYCGTGTIAQIFAKK
SESVIGVEIVEEAVEKAKENAELNGLTNTEFICDDCLNFMEKVEKKDVVVLDPPRDGIHPKAIDRLIDINPDKFIYISCN
PITQRMDLDKFIEKGYEIKSLEFFDQFPRTYHCEAVVLLSRK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=363, Percent_Identity=30.0275482093664, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI51173878, Length=363, Percent_Identity=30.0275482093664, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI269784680, Length=361, Percent_Identity=26.8698060941828, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI269784676, Length=361, Percent_Identity=26.8698060941828, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI20149688, Length=361, Percent_Identity=26.8698060941828, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI269784678, Length=377, Percent_Identity=26.2599469496021, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1789148, Length=403, Percent_Identity=28.5359801488834, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787083, Length=376, Percent_Identity=28.1914893617021, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1790403, Length=184, Percent_Identity=29.3478260869565, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997438, Length=190, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322909, Length=395, Percent_Identity=25.8227848101266, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24666579, Length=371, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51134; Mature: 51134

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILEAKVEYNVFPNKGICKIDDNLYSIKNTIQGQTISFQRKRKKKGFIEGKLVEKLEK
CCCHHHHHHEEEECCCCCEEEECCCHHHHHHHCCCCEEHHHHHHHHCCCCCHHHHHHHHC
SPLETIEGCPVNERCGGCIYQKLEYDVECDLKKKTLTELYKDIYDEDIIFHPSPILQGYR
CCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHH
NKMEYTFGDSVKGGPLVLGLHTKNKFYEITDTVDCNIIDEGFNKIRQAVQEYFRDKNYEF
HCCCCCCCCCCCCCCEEEEEECCCCEEEEECCEECEEHHHHHHHHHHHHHHHHHCCCHHH
FKKIKHTGLLRHFIIRKSFSDDEYMINLVTTSDKFDVNDFVEFAKQIDNRIVSIYHTIND
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEHHCC
NISDAVIVDKLELLHGKEYLTEKINGLEFRISPFSFFQPNPAQAEQIYTRALELAGDLSG
CCCCHHHHHHHHHHHCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
KNVYDLYCGTGTIAQIFAKKSESVIGVEIVEEAVEKAKENAELNGLTNTEFICDDCLNFM
CEEEEEEECCCHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EKVEKKDVVVLDPPRDGIHPKAIDRLIDINPDKFIYISCNPITQRMDLDKFIEKGYEIKS
HHHCCCCEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHCCHHHHHHCCCCEEE
LEFFDQFPRTYHCEAVVLLSRK
EHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKKILEAKVEYNVFPNKGICKIDDNLYSIKNTIQGQTISFQRKRKKKGFIEGKLVEKLEK
CCCHHHHHHEEEECCCCCEEEECCCHHHHHHHCCCCEEHHHHHHHHCCCCCHHHHHHHHC
SPLETIEGCPVNERCGGCIYQKLEYDVECDLKKKTLTELYKDIYDEDIIFHPSPILQGYR
CCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHH
NKMEYTFGDSVKGGPLVLGLHTKNKFYEITDTVDCNIIDEGFNKIRQAVQEYFRDKNYEF
HCCCCCCCCCCCCCCEEEEEECCCCEEEEECCEECEEHHHHHHHHHHHHHHHHHCCCHHH
FKKIKHTGLLRHFIIRKSFSDDEYMINLVTTSDKFDVNDFVEFAKQIDNRIVSIYHTIND
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEHHCC
NISDAVIVDKLELLHGKEYLTEKINGLEFRISPFSFFQPNPAQAEQIYTRALELAGDLSG
CCCCHHHHHHHHHHHCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
KNVYDLYCGTGTIAQIFAKKSESVIGVEIVEEAVEKAKENAELNGLTNTEFICDDCLNFM
CEEEEEEECCCHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EKVEKKDVVVLDPPRDGIHPKAIDRLIDINPDKFIYISCNPITQRMDLDKFIEKGYEIKS
HHHCCCCEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHCCHHHHHHCCCCEEE
LEFFDQFPRTYHCEAVVLLSRK
EHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]