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The map label for this gene is era [H]

Identifier: 169824433

GI number: 169824433

Start: 798736

End: 799620

Strand: Direct

Name: era [H]

Synonym: FMG_0736

Alternate gene names: 169824433

Gene position: 798736-799620 (Clockwise)

Preceding gene: 169824432

Following gene: 169824434

Centisome position: 44.43

GC content: 28.14

Gene sequence:

>885_bases
ATGTTTAAATCAGGATTTGTTTCAGTAATAGGAAGAAGTAATGTAGGGAAATCAACTCTTTTAAATAGAGTTTTAGGAGA
AAAGCTAACGATTATTTCAGACAAACCACAAACTACCAGAAATAAAATTCAACTTATATATACAGATGAAAATATGCAAG
CAATATTTCTAGATACACCAGGAATACAAACACCAAAAAATAAACTTGGAGATTATATGCTTAAAGTATCAATGTCAACA
TTGAATGAGGTTGATGTTATAACATATATTGTTGATACCACAGAAGAAATAGGAAAGCTGGATTCAGAAATTATAGAAAA
ACTAAGATTAGTTAATACAAAAATTATTTTATTAATCAATAAAATTGATAAAATAGCAAGTGATAAAGTTAATGAACTAG
TAGAAATGTATACTAAAGTTGGAATATTCGAACAAATAATTCCTATTAGTGCTTTGAATGGGGATAATATTGAAGGATAT
TTAACCTCTCTTCGTAATACATTACCAGATGGACCTATGTATTATGATAAAGATAGTGTAACTGATCAACCTATTAGGCA
GATTGTACAAGAACTAATCAGGGAAAAGGCACTTATCAATTTATCTGATGAATTACCACACGGAATAGCTATAACTATTG
AAAAATTCAAAGAGAGACAAGATAAGAAGTTAATAGATATAGACGCTACAATTATCGTTGAGAAAAAAAGTCATAAAGGT
ATGGTAATTGGGAAAAAAGGATCAATGATTAAAAAAATAGGAACTGATGCCAGAATAGATATAGAGCAATTATTAGATAC
TAAAGTAAATCTTAAACTTTGGGTTAAAATAGATGAAGAGTGGAGAAATAAAGATTCTAGATTAAGGTATTTGGGATACA
ACTAA

Upstream 100 bases:

>100_bases
AATGAAGATACTAGGATAATAGTAGCTAGAAATGATAAAGATTACAAAATTTATAATATTGAAGAGTTACTACCTCATGG
ATTTAGTGGAGATGATGTAA

Downstream 100 bases:

>100_bases
TGGATAAAGACTACATCAAGACACAAGCGATTGTACTAGAACATATTGTTTATGGAGAAAACTCTATAATATTAAATGTT
TTTAGTAAAGAAGAAGGTAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MFKSGFVSVIGRSNVGKSTLLNRVLGEKLTIISDKPQTTRNKIQLIYTDENMQAIFLDTPGIQTPKNKLGDYMLKVSMST
LNEVDVITYIVDTTEEIGKLDSEIIEKLRLVNTKIILLINKIDKIASDKVNELVEMYTKVGIFEQIIPISALNGDNIEGY
LTSLRNTLPDGPMYYDKDSVTDQPIRQIVQELIREKALINLSDELPHGIAITIEKFKERQDKKLIDIDATIIVEKKSHKG
MVIGKKGSMIKKIGTDARIDIEQLLDTKVNLKLWVKIDEEWRNKDSRLRYLGYN

Sequences:

>Translated_294_residues
MFKSGFVSVIGRSNVGKSTLLNRVLGEKLTIISDKPQTTRNKIQLIYTDENMQAIFLDTPGIQTPKNKLGDYMLKVSMST
LNEVDVITYIVDTTEEIGKLDSEIIEKLRLVNTKIILLINKIDKIASDKVNELVEMYTKVGIFEQIIPISALNGDNIEGY
LTSLRNTLPDGPMYYDKDSVTDQPIRQIVQELIREKALINLSDELPHGIAITIEKFKERQDKKLIDIDATIIVEKKSHKG
MVIGKKGSMIKKIGTDARIDIEQLLDTKVNLKLWVKIDEEWRNKDSRLRYLGYN
>Mature_294_residues
MFKSGFVSVIGRSNVGKSTLLNRVLGEKLTIISDKPQTTRNKIQLIYTDENMQAIFLDTPGIQTPKNKLGDYMLKVSMST
LNEVDVITYIVDTTEEIGKLDSEIIEKLRLVNTKIILLINKIDKIASDKVNELVEMYTKVGIFEQIIPISALNGDNIEGY
LTSLRNTLPDGPMYYDKDSVTDQPIRQIVQELIREKALINLSDELPHGIAITIEKFKERQDKKLIDIDATIIVEKKSHKG
MVIGKKGSMIKKIGTDARIDIEQLLDTKVNLKLWVKIDEEWRNKDSRLRYLGYN

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=293, Percent_Identity=37.2013651877133, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082120, Length=168, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646434, Length=307, Percent_Identity=21.4983713355049, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33484; Mature: 33484

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSGFVSVIGRSNVGKSTLLNRVLGEKLTIISDKPQTTRNKIQLIYTDENMQAIFLDTP
CCCCCCEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEECCCCEEEEEECC
GIQTPKNKLGDYMLKVSMSTLNEVDVITYIVDTTEEIGKLDSEIIEKLRLVNTKIILLIN
CCCCCHHHHHHHEEEEEHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEE
KIDKIASDKVNELVEMYTKVGIFEQIIPISALNGDNIEGYLTSLRNTLPDGPMYYDKDSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEECCCCC
TDQPIRQIVQELIREKALINLSDELPHGIAITIEKFKERQDKKLIDIDATIIVEKKSHKG
CHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEHHHHHHCCCEEEEECEEEEEEECCCCC
MVIGKKGSMIKKIGTDARIDIEQLLDTKVNLKLWVKIDEEWRNKDSRLRYLGYN
EEEECCCCHHHHCCCCCCEEHHHHHCCCCCEEEEEEECHHHCCCCCEEEEECCC
>Mature Secondary Structure
MFKSGFVSVIGRSNVGKSTLLNRVLGEKLTIISDKPQTTRNKIQLIYTDENMQAIFLDTP
CCCCCCEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEECCCCEEEEEECC
GIQTPKNKLGDYMLKVSMSTLNEVDVITYIVDTTEEIGKLDSEIIEKLRLVNTKIILLIN
CCCCCHHHHHHHEEEEEHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEE
KIDKIASDKVNELVEMYTKVGIFEQIIPISALNGDNIEGYLTSLRNTLPDGPMYYDKDSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEECCCCC
TDQPIRQIVQELIREKALINLSDELPHGIAITIEKFKERQDKKLIDIDATIIVEKKSHKG
CHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEHHHHHHCCCEEEEECEEEEEEECCCCC
MVIGKKGSMIKKIGTDARIDIEQLLDTKVNLKLWVKIDEEWRNKDSRLRYLGYN
EEEECCCCHHHHCCCCCCEEHHHHHCCCCCEEEEEEECHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA