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The map label for this gene is cdd [H]

Identifier: 169824432

GI number: 169824432

Start: 798348

End: 798743

Strand: Direct

Name: cdd [H]

Synonym: FMG_0735

Alternate gene names: 169824432

Gene position: 798348-798743 (Clockwise)

Preceding gene: 169824431

Following gene: 169824433

Centisome position: 44.41

GC content: 29.8

Gene sequence:

>396_bases
ATGGAAATTAATAAAATGTACAAAATTGCTTTGCAATATAAACAAAACGCATACACACCATATTCTAACTATAATGTAGG
ATGCTGTGTAAAAGACACAGACGGAAACTATTTTGGGGGTTGTAATATCGAAAATGCATCATTCAGTCCCACTATTTGTG
CTGAAAGAACTGCTATTTCAAAGATGGTTTCTGAAGGATGTAAATTAATAGATACAATTTTAATAATTGGAGATTCAGAT
TTTACGTATCCTTGTGGAGTTTGTAGACAGGTGATTAAAGAATTTTCTAATGAAGATACTAGGATAATAGTAGCTAGAAA
TGATAAAGATTACAAAATTTATAATATTGAAGAGTTACTACCTCATGGATTTAGTGGAGATGATGTAAATGTTTAA

Upstream 100 bases:

>100_bases
GTAGAAGGCAAGATCCATACGTTAAGTCAAGTTATAGTTGGTGGTATTATTGGGACTTTAGTAGCTATATTATTATTTAA
AGTGATTATTTAGGAGTATT

Downstream 100 bases:

>100_bases
ATCAGGATTTGTTTCAGTAATAGGAAGAAGTAATGTAGGGAAATCAACTCTTTTAAATAGAGTTTTAGGAGAAAAGCTAA
CGATTATTTCAGACAAACCA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MEINKMYKIALQYKQNAYTPYSNYNVGCCVKDTDGNYFGGCNIENASFSPTICAERTAISKMVSEGCKLIDTILIIGDSD
FTYPCGVCRQVIKEFSNEDTRIIVARNDKDYKIYNIEELLPHGFSGDDVNV

Sequences:

>Translated_131_residues
MEINKMYKIALQYKQNAYTPYSNYNVGCCVKDTDGNYFGGCNIENASFSPTICAERTAISKMVSEGCKLIDTILIIGDSD
FTYPCGVCRQVIKEFSNEDTRIIVARNDKDYKIYNIEELLPHGFSGDDVNV
>Mature_131_residues
MEINKMYKIALQYKQNAYTPYSNYNVGCCVKDTDGNYFGGCNIENASFSPTICAERTAISKMVSEGCKLIDTILIIGDSD
FTYPCGVCRQVIKEFSNEDTRIIVARNDKDYKIYNIEELLPHGFSGDDVNV

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=130, Percent_Identity=40.7692307692308, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=34.6456692913386, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551074, Length=118, Percent_Identity=38.9830508474576, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=133, Percent_Identity=35.3383458646617, Blast_Score=84, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19920920, Length=121, Percent_Identity=47.1074380165289, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24582741, Length=130, Percent_Identity=37.6923076923077, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24582744, Length=137, Percent_Identity=35.036496350365, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14753; Mature: 14753

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINKMYKIALQYKQNAYTPYSNYNVGCCVKDTDGNYFGGCNIENASFSPTICAERTAIS
CCCHHHEEEEEEECCCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCHHHHHHHHH
KMVSEGCKLIDTILIIGDSDFTYPCGVCRQVIKEFSNEDTRIIVARNDKDYKIYNIEELL
HHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHHC
PHGFSGDDVNV
CCCCCCCCCCC
>Mature Secondary Structure
MEINKMYKIALQYKQNAYTPYSNYNVGCCVKDTDGNYFGGCNIENASFSPTICAERTAIS
CCCHHHEEEEEEECCCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCHHHHHHHHH
KMVSEGCKLIDTILIIGDSDFTYPCGVCRQVIKEFSNEDTRIIVARNDKDYKIYNIEELL
HHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHHC
PHGFSGDDVNV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349569 [H]