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The map label for this gene is yfjD [C]

Identifier: 169824380

GI number: 169824380

Start: 745224

End: 746567

Strand: Direct

Name: yfjD [C]

Synonym: FMG_0683

Alternate gene names: 169824380

Gene position: 745224-746567 (Clockwise)

Preceding gene: 169824379

Following gene: 169824381

Centisome position: 41.46

GC content: 28.5

Gene sequence:

>1344_bases
ATGGACGAAGTCGGGCCCAATCTTTTTATAGAATTGGTAATTTTATTGGTACTCATAATAATTAATGCTTTTTTTTCAGC
AAGTGAAATAGCTATAGTATCTTGTGACAAAAATAAGCTTAGAGCTATGAGTGAAGATGGTAATGATAAAGCAAAATTAG
TTTTAGAACAATTTGAAAAACACACAAAATTTTTATCTACTATTCAGGTTATTTTAACTTACATTGGATTTGTTGCTGCT
GCAATATGTTCCTCTAGTTTAAGTGGGAGTTTGAGTAAAAAATTAGTATTTTTAGGACTAAATAGCTCCTTGACTTATTG
GTTATCGGTTTGTATAGTACTTTTAGTTTTGTCATTTTTGTATATTTTGTTTGGACAATTGATTCCGAAAAGGATTGCTT
TAAGTGTTGCGGATTCTTTTGCACTATTTTCAATCAGTGCTGTAAAATTTGTTTATTTTATCTTGAAACCATTTGTTTTC
TTACTTTCAAGGGCAACAAAGCTTATATTAAGTATAATTGGAATTAAAACCTTGAATGTTGAAAGCAAGATAACTGTTGA
AGAAATAAAGTCAATGGTAGAAGTGGGAAAAGAACAAGGTATTATAAATTCAAATGAAAAAGACATGATTGATGCTGTTA
TAAACTTTAATGAAAAAACTGCTGAAGAAATTATGACAGCAAGGACAGAAGTTTTTGCTATCGATCTTGAAGATTGTATC
GAAGATTACTTGGATAAATTAATGGAACTTAAATTTTCAAGAATTCCAATTTATGAAGGTGATATTGACAATATTCTAGG
CATTATTTATATTAAAGACTATATGAGCGAAGCTTACAAACTTGGATTTAATAATGTAGATTTAAGAAAAATTTTGAAAC
CTGCGTATTTCATATCTGAAACTAAAAATATCAATGATTTATTTTCAGATATGAAAAAGAAGAGAATTCATATGGCAATA
CTAATTGATGAGTATGGTGGATTTTCAGGAATTGTATCAATGGAAGATTTGATTGAAGAGATAGTTGGAAATATTGAGGA
TGAATATGATCATGAGGCACCAGATATTGTTCAAGTAGATAAATTCAATTATATCGTGAAAGGAAGTACTTCTATAAAGG
AAATTAATTCTAATATAGGACTTGAAATTGATGAACTCTCTGACGATTACGATACATTAGGCGGTATGCTAATAAATCGA
TTAGGATATATACCTGAAGATGGGTTTAAAAGGAAAATTGATATTGATGGAGTTTTGTACAATATAATTTTTGTAGAAGA
TAAAAGGATTAAAAAGGTAAAAATTACATTACCTAAGAACTTTTTTGAACAGGTGAGTAAATGA

Upstream 100 bases:

>100_bases
AATGAAATCTGTACTTTACAGATACATTCCGTTTAATTTTGTTTTATTTTAATTCTAAATTATTGTATAATATTAGTATG
TATAATTTTAGGAGGATTAA

Downstream 100 bases:

>100_bases
TTATTATAAAAAATAAAGACGAAATAGAAAAAATGGACATTTCTGGAAATGTAATTTCGGGTATGCACGAAGCGTTAAGA
GAATATGTTAAACCGGGATT

Product: putative hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDEVGPNLFIELVILLVLIIINAFFSASEIAIVSCDKNKLRAMSEDGNDKAKLVLEQFEKHTKFLSTIQVILTYIGFVAA
AICSSSLSGSLSKKLVFLGLNSSLTYWLSVCIVLLVLSFLYILFGQLIPKRIALSVADSFALFSISAVKFVYFILKPFVF
LLSRATKLILSIIGIKTLNVESKITVEEIKSMVEVGKEQGIINSNEKDMIDAVINFNEKTAEEIMTARTEVFAIDLEDCI
EDYLDKLMELKFSRIPIYEGDIDNILGIIYIKDYMSEAYKLGFNNVDLRKILKPAYFISETKNINDLFSDMKKKRIHMAI
LIDEYGGFSGIVSMEDLIEEIVGNIEDEYDHEAPDIVQVDKFNYIVKGSTSIKEINSNIGLEIDELSDDYDTLGGMLINR
LGYIPEDGFKRKIDIDGVLYNIIFVEDKRIKKVKITLPKNFFEQVSK

Sequences:

>Translated_447_residues
MDEVGPNLFIELVILLVLIIINAFFSASEIAIVSCDKNKLRAMSEDGNDKAKLVLEQFEKHTKFLSTIQVILTYIGFVAA
AICSSSLSGSLSKKLVFLGLNSSLTYWLSVCIVLLVLSFLYILFGQLIPKRIALSVADSFALFSISAVKFVYFILKPFVF
LLSRATKLILSIIGIKTLNVESKITVEEIKSMVEVGKEQGIINSNEKDMIDAVINFNEKTAEEIMTARTEVFAIDLEDCI
EDYLDKLMELKFSRIPIYEGDIDNILGIIYIKDYMSEAYKLGFNNVDLRKILKPAYFISETKNINDLFSDMKKKRIHMAI
LIDEYGGFSGIVSMEDLIEEIVGNIEDEYDHEAPDIVQVDKFNYIVKGSTSIKEINSNIGLEIDELSDDYDTLGGMLINR
LGYIPEDGFKRKIDIDGVLYNIIFVEDKRIKKVKITLPKNFFEQVSK
>Mature_447_residues
MDEVGPNLFIELVILLVLIIINAFFSASEIAIVSCDKNKLRAMSEDGNDKAKLVLEQFEKHTKFLSTIQVILTYIGFVAA
AICSSSLSGSLSKKLVFLGLNSSLTYWLSVCIVLLVLSFLYILFGQLIPKRIALSVADSFALFSISAVKFVYFILKPFVF
LLSRATKLILSIIGIKTLNVESKITVEEIKSMVEVGKEQGIINSNEKDMIDAVINFNEKTAEEIMTARTEVFAIDLEDCI
EDYLDKLMELKFSRIPIYEGDIDNILGIIYIKDYMSEAYKLGFNNVDLRKILKPAYFISETKNINDLFSDMKKKRIHMAI
LIDEYGGFSGIVSMEDLIEEIVGNIEDEYDHEAPDIVQVDKFNYIVKGSTSIKEINSNIGLEIDELSDDYDTLGGMLINR
LGYIPEDGFKRKIDIDGVLYNIIFVEDKRIKKVKITLPKNFFEQVSK

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=379, Percent_Identity=29.5514511873351, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI40068053, Length=365, Percent_Identity=23.2876712328767, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI40068055, Length=365, Percent_Identity=23.2876712328767, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI94681046, Length=353, Percent_Identity=24.3626062322946, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI40068051, Length=323, Percent_Identity=21.0526315789474, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI145693175, Length=435, Percent_Identity=26.6666666666667, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=25.3456221198157, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786879, Length=261, Percent_Identity=29.1187739463602, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87082033, Length=388, Percent_Identity=26.5463917525773, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788119, Length=341, Percent_Identity=26.6862170087977, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50549; Mature: 50549

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEVGPNLFIELVILLVLIIINAFFSASEIAIVSCDKNKLRAMSEDGNDKAKLVLEQFEK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHH
HTKFLSTIQVILTYIGFVAAAICSSSLSGSLSKKLVFLGLNSSLTYWLSVCIVLLVLSFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEEEEECCCHHHHHHHHHHHHHHHHHH
YILFGQLIPKRIALSVADSFALFSISAVKFVYFILKPFVFLLSRATKLILSIIGIKTLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
ESKITVEEIKSMVEVGKEQGIINSNEKDMIDAVINFNEKTAEEIMTARTEVFAIDLEDCI
CCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHHHH
EDYLDKLMELKFSRIPIYEGDIDNILGIIYIKDYMSEAYKLGFNNVDLRKILKPAYFISE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
TKNINDLFSDMKKKRIHMAILIDEYGGFSGIVSMEDLIEEIVGNIEDEYDHEAPDIVQVD
CCCHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCHHCCCCCCCEEEEC
KFNYIVKGSTSIKEINSNIGLEIDELSDDYDTLGGMLINRLGYIPEDGFKRKIDIDGVLY
CCCEEEECCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEE
NIIFVEDKRIKKVKITLPKNFFEQVSK
EEEEEECCCEEEEEEECCHHHHHHHCC
>Mature Secondary Structure
MDEVGPNLFIELVILLVLIIINAFFSASEIAIVSCDKNKLRAMSEDGNDKAKLVLEQFEK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHH
HTKFLSTIQVILTYIGFVAAAICSSSLSGSLSKKLVFLGLNSSLTYWLSVCIVLLVLSFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEEEEECCCHHHHHHHHHHHHHHHHHH
YILFGQLIPKRIALSVADSFALFSISAVKFVYFILKPFVFLLSRATKLILSIIGIKTLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
ESKITVEEIKSMVEVGKEQGIINSNEKDMIDAVINFNEKTAEEIMTARTEVFAIDLEDCI
CCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHHHH
EDYLDKLMELKFSRIPIYEGDIDNILGIIYIKDYMSEAYKLGFNNVDLRKILKPAYFISE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
TKNINDLFSDMKKKRIHMAILIDEYGGFSGIVSMEDLIEEIVGNIEDEYDHEAPDIVQVD
CCCHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCHHCCCCCCCEEEEC
KFNYIVKGSTSIKEINSNIGLEIDELSDDYDTLGGMLINRLGYIPEDGFKRKIDIDGVLY
CCCEEEECCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEE
NIIFVEDKRIKKVKITLPKNFFEQVSK
EEEEEECCCEEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]