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The map label for this gene is hppA

Identifier: 169824379

GI number: 169824379

Start: 743088

End: 745100

Strand: Direct

Name: hppA

Synonym: FMG_0682

Alternate gene names: 169824379

Gene position: 743088-745100 (Clockwise)

Preceding gene: 169824378

Following gene: 169824380

Centisome position: 41.34

GC content: 36.26

Gene sequence:

>2013_bases
ATGGACAATATGTATTACTATTTAGCTATTGCAGCAGGTATTATCGCTTTATTATTTGCTGCAATAAAGTTTAGTAGCAT
AAGTAAAAAAGGTGCTGGTAATGAAAGAATGAAGGAGATATCTGGATTTATTCATGATGGAGCTATGGCTTATCTTTCTC
GTCAATACAAAGCACTTATTATTTTTGTTGTTGTAGTATGCGTAATTTTAGGTGTTGCAATTGATTATAAGACAGCAATT
TGCTTCTTAGCTGGTGCAATATTTAGTGTACTTGCTGGATATATTGGAATGCAAGCTGCTACAAAGGCAAACGTTAGGAC
AGCTAACTCAGCAAAAGAAGAAGGAATGAACGGAGCATTAAACGTTGCATTTTCAGGTGGAGCAGTAATGGGAATGTGCG
TTGTTGGATTAGGAATTTTAGGTATAACTCTTTCTTATATTATTTTCCAAGACGCAGAAATAGTTACTGGATTTAGTTTT
GGTGCTTCTTCTATAGCGTTGTTTGCCAGAGTTGGTGGCGGTATTTACACTAAAGCTGCCGATGTTGGTGCAGACTTGGT
TGGTAAAGTAGAAGCAGGTATTCCTGAAGATGACCCTAGAAACCCTGCAGTAATCGCAGATAACGTTGGTGATAACGTAG
GGGACGTTGCAGGTATGGGAGCTGACTTGTTTGAATCTTACGCTGGTAGTATTTTATCAGGGATTACATTAGGTTTATTA
GCTTACAAAGAAGCAGGTGTGTCTTTTGCAATTGCAATAGCAGCTATAGGAGTCATTGCTTCTATTATAGGTGTATTTAC
AGTAAGGGGAGGAAAAGATCCTCAAAAATCTTTAAATACTGGTACTATTATTAGTTCTATTTTAGCAATCGCAGGATCAT
TCTTCTTATCAAGAACTATTCTTGGTAACAATAATGCGTTCTTCTCTGTTTTAGCAGGTATTTTAGTTGGATTGATAATT
TCTCAATTTACAGAATATTACACATCTGAAGACAAAAAACCAGTTCAAAAAATAGCTGAAGAATCTGAAACAGGTTCATC
TACTAACATTATTTCAGGATTAGCTACAGGTATGAAATCAACAACTGGCCCTATTATTGTTATAGCTATTGGTATAATTG
TTTCATTCTTTGCATCAAATGGTGCAACTAATCCTACAGAAGGTTTATACGGTATTGCAGTAGCAGCTATTGGTATGTTG
TCAACTTGTGGTATGACAATTGCTGTAGATGCTTACGGTCCAATAGCCGATAACGCTGGTGGTATTGCAGAAATGTGTGA
ATTACCAGAAGATGTTAGAAATATTACAGATAAATTAGACTCAGTTGGTAATACAACTGCAGCCATTGGTAAAGGATTTG
CAATTGGTAGTGCTGCATTAACAGCTTTGGCACTATTTGCATCATACACTGCAGTTGTAGGATTAAAACAAATCAATGTA
ACAAGCCCTGAAGTAGTAGCTGGTATGTTCATTGGTGGTATGTTACCATTCTTATTCTCAGCGTTAACTATGGATGCTGT
AGGAACTGCTGCAAATGATATGATTGTAGAAGTTAGAAGACAATTTAAAGAGTTCCCTGGAATAATGGAAGGAACTCAAC
AACCAGATTACAAAAAATGTGTTGATATTTCTACTGGAGCTGCATTAAGACAAATGATAGTACCTGGATTATTAGCTGTA
ATATGTCCTGTAATAATGGGATTTTTATTAGGTGCAGAAGCTCTAGGAGGACTTTTAGCAGGTTCACTTGTAACAGGCGT
TTTAATGGCGATATTTATGTCAAACAGTGGTGGAGCATGGGATAATGCTAAGAAGTATATTGAATCAGGTCAACATGGTG
GAAAAGGATCAGATGCTCATAAAGCAGCTGTTGTAGGAGATACTGTAGGGGACCCATTCAAAGACACATCAGGCCCATCA
TTAAATATCCTAATTAAATTGATGACAGTAGTTTCATTAGTATTTGCACCATTAATTGCTCAACATGGTGGAATAATATT
AAATTTATTCTAA

Upstream 100 bases:

>100_bases
TTATATCAACAGAGTCGTAGTTGTATCATCAGTTATATTCTTAGTTTCAGCTTTGGCGTTAGCATATATAAAATAATTTA
ATAGTTGAAAGGAGTAAATC

Downstream 100 bases:

>100_bases
ATAATAAAAAATTTTTTAAACGGAATGAAATCTGTACTTTACAGATACATTCCGTTTAATTTTGTTTTATTTTAATTCTA
AATTATTGTATAATATTAGT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MDNMYYYLAIAAGIIALLFAAIKFSSISKKGAGNERMKEISGFIHDGAMAYLSRQYKALIIFVVVVCVILGVAIDYKTAI
CFLAGAIFSVLAGYIGMQAATKANVRTANSAKEEGMNGALNVAFSGGAVMGMCVVGLGILGITLSYIIFQDAEIVTGFSF
GASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYAGSILSGITLGLL
AYKEAGVSFAIAIAAIGVIASIIGVFTVRGGKDPQKSLNTGTIISSILAIAGSFFLSRTILGNNNAFFSVLAGILVGLII
SQFTEYYTSEDKKPVQKIAEESETGSSTNIISGLATGMKSTTGPIIVIAIGIIVSFFASNGATNPTEGLYGIAVAAIGML
STCGMTIAVDAYGPIADNAGGIAEMCELPEDVRNITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYTAVVGLKQINV
TSPEVVAGMFIGGMLPFLFSALTMDAVGTAANDMIVEVRRQFKEFPGIMEGTQQPDYKKCVDISTGAALRQMIVPGLLAV
ICPVIMGFLLGAEALGGLLAGSLVTGVLMAIFMSNSGGAWDNAKKYIESGQHGGKGSDAHKAAVVGDTVGDPFKDTSGPS
LNILIKLMTVVSLVFAPLIAQHGGIILNLF

Sequences:

>Translated_670_residues
MDNMYYYLAIAAGIIALLFAAIKFSSISKKGAGNERMKEISGFIHDGAMAYLSRQYKALIIFVVVVCVILGVAIDYKTAI
CFLAGAIFSVLAGYIGMQAATKANVRTANSAKEEGMNGALNVAFSGGAVMGMCVVGLGILGITLSYIIFQDAEIVTGFSF
GASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYAGSILSGITLGLL
AYKEAGVSFAIAIAAIGVIASIIGVFTVRGGKDPQKSLNTGTIISSILAIAGSFFLSRTILGNNNAFFSVLAGILVGLII
SQFTEYYTSEDKKPVQKIAEESETGSSTNIISGLATGMKSTTGPIIVIAIGIIVSFFASNGATNPTEGLYGIAVAAIGML
STCGMTIAVDAYGPIADNAGGIAEMCELPEDVRNITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYTAVVGLKQINV
TSPEVVAGMFIGGMLPFLFSALTMDAVGTAANDMIVEVRRQFKEFPGIMEGTQQPDYKKCVDISTGAALRQMIVPGLLAV
ICPVIMGFLLGAEALGGLLAGSLVTGVLMAIFMSNSGGAWDNAKKYIESGQHGGKGSDAHKAAVVGDTVGDPFKDTSGPS
LNILIKLMTVVSLVFAPLIAQHGGIILNLF
>Mature_670_residues
MDNMYYYLAIAAGIIALLFAAIKFSSISKKGAGNERMKEISGFIHDGAMAYLSRQYKALIIFVVVVCVILGVAIDYKTAI
CFLAGAIFSVLAGYIGMQAATKANVRTANSAKEEGMNGALNVAFSGGAVMGMCVVGLGILGITLSYIIFQDAEIVTGFSF
GASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYAGSILSGITLGLL
AYKEAGVSFAIAIAAIGVIASIIGVFTVRGGKDPQKSLNTGTIISSILAIAGSFFLSRTILGNNNAFFSVLAGILVGLII
SQFTEYYTSEDKKPVQKIAEESETGSSTNIISGLATGMKSTTGPIIVIAIGIIVSFFASNGATNPTEGLYGIAVAAIGML
STCGMTIAVDAYGPIADNAGGIAEMCELPEDVRNITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYTAVVGLKQINV
TSPEVVAGMFIGGMLPFLFSALTMDAVGTAANDMIVEVRRQFKEFPGIMEGTQQPDYKKCVDISTGAALRQMIVPGLLAV
ICPVIMGFLLGAEALGGLLAGSLVTGVLMAIFMSNSGGAWDNAKKYIESGQHGGKGSDAHKAAVVGDTVGDPFKDTSGPS
LNILIKLMTVVSLVFAPLIAQHGGIILNLF

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 68758; Mature: 68758

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNMYYYLAIAAGIIALLFAAIKFSSISKKGAGNERMKEISGFIHDGAMAYLSRQYKALI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFVVVVCVILGVAIDYKTAICFLAGAIFSVLAGYIGMQAATKANVRTANSAKEEGMNGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEE
NVAFSGGAVMGMCVVGLGILGITLSYIIFQDAEIVTGFSFGASSIALFARVGGGIYTKAA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHCCCCEEHHH
DVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYAGSILSGITLGLL
HHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AYKEAGVSFAIAIAAIGVIASIIGVFTVRGGKDPQKSLNTGTIISSILAIAGSFFLSRTI
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGNNNAFFSVLAGILVGLIISQFTEYYTSEDKKPVQKIAEESETGSSTNIISGLATGMKS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCC
TTGPIIVIAIGIIVSFFASNGATNPTEGLYGIAVAAIGMLSTCGMTIAVDAYGPIADNAG
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
GIAEMCELPEDVRNITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYTAVVGLKQINV
CHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSPEVVAGMFIGGMLPFLFSALTMDAVGTAANDMIVEVRRQFKEFPGIMEGTQQPDYKKC
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHH
VDISTGAALRQMIVPGLLAVICPVIMGFLLGAEALGGLLAGSLVTGVLMAIFMSNSGGAW
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DNAKKYIESGQHGGKGSDAHKAAVVGDTVGDPFKDTSGPSLNILIKLMTVVSLVFAPLIA
HHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QHGGIILNLF
HCCCEEEEEC
>Mature Secondary Structure
MDNMYYYLAIAAGIIALLFAAIKFSSISKKGAGNERMKEISGFIHDGAMAYLSRQYKALI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFVVVVCVILGVAIDYKTAICFLAGAIFSVLAGYIGMQAATKANVRTANSAKEEGMNGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEE
NVAFSGGAVMGMCVVGLGILGITLSYIIFQDAEIVTGFSFGASSIALFARVGGGIYTKAA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHCCCCEEHHH
DVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYAGSILSGITLGLL
HHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AYKEAGVSFAIAIAAIGVIASIIGVFTVRGGKDPQKSLNTGTIISSILAIAGSFFLSRTI
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGNNNAFFSVLAGILVGLIISQFTEYYTSEDKKPVQKIAEESETGSSTNIISGLATGMKS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCC
TTGPIIVIAIGIIVSFFASNGATNPTEGLYGIAVAAIGMLSTCGMTIAVDAYGPIADNAG
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
GIAEMCELPEDVRNITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYTAVVGLKQINV
CHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSPEVVAGMFIGGMLPFLFSALTMDAVGTAANDMIVEVRRQFKEFPGIMEGTQQPDYKKC
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHH
VDISTGAALRQMIVPGLLAVICPVIMGFLLGAEALGGLLAGSLVTGVLMAIFMSNSGGAW
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DNAKKYIESGQHGGKGSDAHKAAVVGDTVGDPFKDTSGPSLNILIKLMTVVSLVFAPLIA
HHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QHGGIILNLF
HCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]