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The map label for this gene is recG [H]

Identifier: 169824372

GI number: 169824372

Start: 737988

End: 740024

Strand: Direct

Name: recG [H]

Synonym: FMG_0675

Alternate gene names: 169824372

Gene position: 737988-740024 (Clockwise)

Preceding gene: 169824371

Following gene: 169824373

Centisome position: 41.05

GC content: 28.18

Gene sequence:

>2037_bases
ATGCAATTATCAGAAATAAAAGGAATAGGAAAGAAAAAATTAGAAGTATTAAACTCTATGGGTATTATCAATATTAATGA
TTTGTTGAATTATTTTCCTTACAGATACGAAAACAGATCTATTATTAAAAACATTATTGATACGAGAGATGAAGAAAATT
GTGTTATAAAGGTAAAGTTTATTTCTAAACCTATAACTAAATATTTAAGAAGAAATCTAAACTTAACAACTGCTATAGCA
TTTGATGATACTTCAAAAATTAGCGTGTCATGGTTTAATCAACCTTTTATTAGAAATCAAATTTTGCCAAATACAACTTA
TTATCTATATGGAAAGATACAAAGAGTCCAAAACCAATTTAAAATATCTTCACCAATATTAAGTAAAACTTTTGGCGGGA
AATTGGGCATAATTTATCCAATTTACAAAGTTAAAAAAGGCATAACAAATAACGATATGATTAAGTTTGTTGATTTTGCT
ATTAAACATTGTATTGATGAAATAAAAAATGTTATTCCGTATAGTATGATTAAAAACTATGATATTGAAAATAAAAGAAA
TGCGATAAAAAACATTCATAAACCAGTTGATTACATGCAATTTAAAAGAGCTAGAACTGCTCTTGTTCTTGAAGAAGTTA
TTATAATGCAACTTGCAATGAAATCGATGAAAACATCACTCAACCAACAAAATTATATAAAACTTCAATCAGATGAAAGT
ATAAATATTTTCATAAATTCTTTAAAATTTGAACTTACAAAAGGACAACTTGAAGCAATAAAAGATATCGAAATGGACAT
GACATCTGAAAAGAGAATGAATAGACTGGTTCAAGGTGATGTTGGAAGTGGCAAGACAATAGTAGCGGAGGCAGCGATTT
TTAAATCACATTCTAGTGGTTACCAATCTGCCTTTATGGCTCCTACAGATATATTAGCGACACAACATTATGAAAGCTTG
TCAGAAGATTTTTCAAAATTTGGAATAAAAGTTTGCTTATTGAAATCTGACTTAACAAAATCAGAAAAAGATTTGGTTCT
AAAAGGAATAAAATCAGGATATTTCGATGTTATAGTAGGAACCCATGCAATAATACAAGATTTTGTTGAATTTAAAAGAC
TTGGACTTGTAATTACTGATGAACAACATAGATTTGGAGTGGGTCAAAGAAAAAAAATTTCTGACAAAGGTCAAAATCCA
GATGTTCTTGTAATGACAGCTACTCCAATTCCTAGAACTTTAGCACTTTCTTATTACGGAGATTTAGATATATCAACAAT
AAATGAAATGCCTAAAGGAAGAAAAATAATAGAAACATATTCTGTTGGCTTTAGCTACGAAAAAAGGATAGCGGATTTTA
TAAGAAAACAAGTTGATAATGGGTTTCAGGCATATATCGTTTGTCCATTGATAGAAGAATCTGAATCTTTAGAATTAGAA
AATGTAACGGAACTTTACAATAGGCTTACTGGTGAATATTTTTCAGATATAAATGTTGGAATGTTACATGGAAAAATGAA
ATCCTCGGAAAAAGAAGAAACTATGAAAGATTTTGTAGACGGTAAAACAAAAATACTTGTATCTACAACTGTTATTGAGG
TTGGAGTTAATGTTAGAAAAGCAAATGTAATAGTTATTTATAACGCTGAAAGATTTGGACTTTCACAACTTCATCAACTT
AGGGGAAGAGTAGGTAGATCATCAGATCAATCATATTGTATACTTATCAATAAAGCACATTCTGATGAGCAAATGGAAAG
AATGAATATTATGGTCAAGACAAATAGCGGATTTGAACTATCACAAAAAGATTTGATGATGAGAGGTAGTGGTGATTTAT
TAGGAACTAGACAATCAGGAATACCGCTTTTAAATATCGCAGATCTTGAAAAAGATTATGATTTGATAGAAAAAGCAGCG
GTGATAACTGATTATATCTACACTAATGATTTGTTAAAAAATAAAGAATATAGTTATTTAAATGAAGAAATAAACAAATT
TAAAGATAAATTATTAGAAAATGTTATTTTTAATTGA

Upstream 100 bases:

>100_bases
TCAATAGAATAACTCCTTACAAAGAATAACAAATAATAGATCGATTTTATCGGTCTATTATTTGTATTACTAATGTAAGG
ATTTTTTTGTGTGGTGAATT

Downstream 100 bases:

>100_bases
GGTGAGAAATGAAAGTTATTTCAGGAAAAATGAGAGGTATGAACTTAAATACTGATTTAGATAGATTTACAAGACCAACT
GAAGGCAAAATAAAAGAAGC

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MQLSEIKGIGKKKLEVLNSMGIININDLLNYFPYRYENRSIIKNIIDTRDEENCVIKVKFISKPITKYLRRNLNLTTAIA
FDDTSKISVSWFNQPFIRNQILPNTTYYLYGKIQRVQNQFKISSPILSKTFGGKLGIIYPIYKVKKGITNNDMIKFVDFA
IKHCIDEIKNVIPYSMIKNYDIENKRNAIKNIHKPVDYMQFKRARTALVLEEVIIMQLAMKSMKTSLNQQNYIKLQSDES
INIFINSLKFELTKGQLEAIKDIEMDMTSEKRMNRLVQGDVGSGKTIVAEAAIFKSHSSGYQSAFMAPTDILATQHYESL
SEDFSKFGIKVCLLKSDLTKSEKDLVLKGIKSGYFDVIVGTHAIIQDFVEFKRLGLVITDEQHRFGVGQRKKISDKGQNP
DVLVMTATPIPRTLALSYYGDLDISTINEMPKGRKIIETYSVGFSYEKRIADFIRKQVDNGFQAYIVCPLIEESESLELE
NVTELYNRLTGEYFSDINVGMLHGKMKSSEKEETMKDFVDGKTKILVSTTVIEVGVNVRKANVIVIYNAERFGLSQLHQL
RGRVGRSSDQSYCILINKAHSDEQMERMNIMVKTNSGFELSQKDLMMRGSGDLLGTRQSGIPLLNIADLEKDYDLIEKAA
VITDYIYTNDLLKNKEYSYLNEEINKFKDKLLENVIFN

Sequences:

>Translated_678_residues
MQLSEIKGIGKKKLEVLNSMGIININDLLNYFPYRYENRSIIKNIIDTRDEENCVIKVKFISKPITKYLRRNLNLTTAIA
FDDTSKISVSWFNQPFIRNQILPNTTYYLYGKIQRVQNQFKISSPILSKTFGGKLGIIYPIYKVKKGITNNDMIKFVDFA
IKHCIDEIKNVIPYSMIKNYDIENKRNAIKNIHKPVDYMQFKRARTALVLEEVIIMQLAMKSMKTSLNQQNYIKLQSDES
INIFINSLKFELTKGQLEAIKDIEMDMTSEKRMNRLVQGDVGSGKTIVAEAAIFKSHSSGYQSAFMAPTDILATQHYESL
SEDFSKFGIKVCLLKSDLTKSEKDLVLKGIKSGYFDVIVGTHAIIQDFVEFKRLGLVITDEQHRFGVGQRKKISDKGQNP
DVLVMTATPIPRTLALSYYGDLDISTINEMPKGRKIIETYSVGFSYEKRIADFIRKQVDNGFQAYIVCPLIEESESLELE
NVTELYNRLTGEYFSDINVGMLHGKMKSSEKEETMKDFVDGKTKILVSTTVIEVGVNVRKANVIVIYNAERFGLSQLHQL
RGRVGRSSDQSYCILINKAHSDEQMERMNIMVKTNSGFELSQKDLMMRGSGDLLGTRQSGIPLLNIADLEKDYDLIEKAA
VITDYIYTNDLLKNKEYSYLNEEINKFKDKLLENVIFN
>Mature_678_residues
MQLSEIKGIGKKKLEVLNSMGIININDLLNYFPYRYENRSIIKNIIDTRDEENCVIKVKFISKPITKYLRRNLNLTTAIA
FDDTSKISVSWFNQPFIRNQILPNTTYYLYGKIQRVQNQFKISSPILSKTFGGKLGIIYPIYKVKKGITNNDMIKFVDFA
IKHCIDEIKNVIPYSMIKNYDIENKRNAIKNIHKPVDYMQFKRARTALVLEEVIIMQLAMKSMKTSLNQQNYIKLQSDES
INIFINSLKFELTKGQLEAIKDIEMDMTSEKRMNRLVQGDVGSGKTIVAEAAIFKSHSSGYQSAFMAPTDILATQHYESL
SEDFSKFGIKVCLLKSDLTKSEKDLVLKGIKSGYFDVIVGTHAIIQDFVEFKRLGLVITDEQHRFGVGQRKKISDKGQNP
DVLVMTATPIPRTLALSYYGDLDISTINEMPKGRKIIETYSVGFSYEKRIADFIRKQVDNGFQAYIVCPLIEESESLELE
NVTELYNRLTGEYFSDINVGMLHGKMKSSEKEETMKDFVDGKTKILVSTTVIEVGVNVRKANVIVIYNAERFGLSQLHQL
RGRVGRSSDQSYCILINKAHSDEQMERMNIMVKTNSGFELSQKDLMMRGSGDLLGTRQSGIPLLNIADLEKDYDLIEKAA
VITDYIYTNDLLKNKEYSYLNEEINKFKDKLLENVIFN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=673, Percent_Identity=34.3239227340267, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787357, Length=388, Percent_Identity=36.5979381443299, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77611; Mature: 77611

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSEIKGIGKKKLEVLNSMGIININDLLNYFPYRYENRSIIKNIIDTRDEENCVIKVKF
CCCHHHCCCCHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEE
ISKPITKYLRRNLNLTTAIAFDDTSKISVSWFNQPFIRNQILPNTTYYLYGKIQRVQNQF
HHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCHHHCCCCCCCEEEEEHHHHHHHHHH
KISSPILSKTFGGKLGIIYPIYKVKKGITNNDMIKFVDFAIKHCIDEIKNVIPYSMIKNY
HCCCCHHHHHCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
DIENKRNAIKNIHKPVDYMQFKRARTALVLEEVIIMQLAMKSMKTSLNQQNYIKLQSDES
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
INIFINSLKFELTKGQLEAIKDIEMDMTSEKRMNRLVQGDVGSGKTIVAEAAIFKSHSSG
EEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCCC
YQSAFMAPTDILATQHYESLSEDFSKFGIKVCLLKSDLTKSEKDLVLKGIKSGYFDVIVG
CCHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCCCEEHHHH
THAIIQDFVEFKRLGLVITDEQHRFGVGQRKKISDKGQNPDVLVMTATPIPRTLALSYYG
HHHHHHHHHHHHHCCEEEECCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEC
DLDISTINEMPKGRKIIETYSVGFSYEKRIADFIRKQVDNGFQAYIVCPLIEESESLELE
CCCHHHHHCCCCCCEEHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHH
NVTELYNRLTGEYFSDINVGMLHGKMKSSEKEETMKDFVDGKTKILVSTTVIEVGVNVRK
HHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEEEEECCEEEE
ANVIVIYNAERFGLSQLHQLRGRVGRSSDQSYCILINKAHSDEQMERMNIMVKTNSGFEL
EEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHEEEEEEECCCCCC
SQKDLMMRGSGDLLGTRQSGIPLLNIADLEKDYDLIEKAAVITDYIYTNDLLKNKEYSYL
CHHHHEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
NEEINKFKDKLLENVIFN
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLSEIKGIGKKKLEVLNSMGIININDLLNYFPYRYENRSIIKNIIDTRDEENCVIKVKF
CCCHHHCCCCHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEE
ISKPITKYLRRNLNLTTAIAFDDTSKISVSWFNQPFIRNQILPNTTYYLYGKIQRVQNQF
HHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCHHHCCCCCCCEEEEEHHHHHHHHHH
KISSPILSKTFGGKLGIIYPIYKVKKGITNNDMIKFVDFAIKHCIDEIKNVIPYSMIKNY
HCCCCHHHHHCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
DIENKRNAIKNIHKPVDYMQFKRARTALVLEEVIIMQLAMKSMKTSLNQQNYIKLQSDES
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
INIFINSLKFELTKGQLEAIKDIEMDMTSEKRMNRLVQGDVGSGKTIVAEAAIFKSHSSG
EEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCCC
YQSAFMAPTDILATQHYESLSEDFSKFGIKVCLLKSDLTKSEKDLVLKGIKSGYFDVIVG
CCHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCCCEEHHHH
THAIIQDFVEFKRLGLVITDEQHRFGVGQRKKISDKGQNPDVLVMTATPIPRTLALSYYG
HHHHHHHHHHHHHCCEEEECCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEC
DLDISTINEMPKGRKIIETYSVGFSYEKRIADFIRKQVDNGFQAYIVCPLIEESESLELE
CCCHHHHHCCCCCCEEHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHH
NVTELYNRLTGEYFSDINVGMLHGKMKSSEKEETMKDFVDGKTKILVSTTVIEVGVNVRK
HHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEEEEECCEEEE
ANVIVIYNAERFGLSQLHQLRGRVGRSSDQSYCILINKAHSDEQMERMNIMVKTNSGFEL
EEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHEEEEEEECCCCCC
SQKDLMMRGSGDLLGTRQSGIPLLNIADLEKDYDLIEKAAVITDYIYTNDLLKNKEYSYL
CHHHHEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
NEEINKFKDKLLENVIFN
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]