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The map label for this gene is ung [H]

Identifier: 169824337

GI number: 169824337

Start: 704017

End: 704694

Strand: Direct

Name: ung [H]

Synonym: FMG_0640

Alternate gene names: 169824337

Gene position: 704017-704694 (Clockwise)

Preceding gene: 169824336

Following gene: 169824338

Centisome position: 39.16

GC content: 28.17

Gene sequence:

>678_bases
ATGAGTGTTAATATAGGAAATAGTTGGGATGAATTGCTAAAGGATGAATGGAACAAAGATTATTATAAAAAAATCAGACA
AGTTTTAATTCATGATTATAAAAATTACAAAGTATATCCAGATATGAATTTTATTTTTGAAGCATTGAAATTAGTTGCTT
TTGAAGATTGTAAGGTTGTGATTTTAGGACAAGACCCATATCATAATCCTAATCAAGCTCATGGACTTAGTTTTTCTGTT
AAACCAGATGTTAAAACGCCTCCTTCATTGATTAATATTTACAAAGAATTGCAAAATGAATTTGGATATCCTATTCCAAA
TAATGGATATTTGATGAAATGGGCAAAACAAGGAGTTTTATTATTAAATACTTCACTTACGGTAATAGAAAACAAACCAA
ATTCTCATTCAAAAATTGGATGGCAAATTTTAACGGATAAAATTATAGAATTATTAGGAAATTCAAATAGACCAATAGTA
TTTATATTGTGGGGCAACAACGCTAGAATGAAAAAAGACTTAATAAAAAGTAAGAATGCTCTCATATTAGAATCGCCACA
CCCTTCTCCATTTTCAGCTAATAGGGGATTTTTCGGTTGCAATCATTTTATAAAAACTAACGATTATTTGATAGATAATG
GTCTAGAACCTATTGATTGGAAGATAGAAAATATATGA

Upstream 100 bases:

>100_bases
TTCCATTTAATTACGATTTTCCTGTGTTTAACGTGGCGGATATAGCTGTTGTTGTATCGTGTATTTTACTTGTTATATTT
AGCTTAAAAGGACATAAATA

Downstream 100 bases:

>100_bases
TTTACGAATTTTTAATTGACGATTCTAATCAAAATACAAGATTGGATGTTTTTTTGGCTAATGAAGTTGAATTATCAAGA
AGTGAAATTCAGAAATTTAT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSVNIGNSWDELLKDEWNKDYYKKIRQVLIHDYKNYKVYPDMNFIFEALKLVAFEDCKVVILGQDPYHNPNQAHGLSFSV
KPDVKTPPSLINIYKELQNEFGYPIPNNGYLMKWAKQGVLLLNTSLTVIENKPNSHSKIGWQILTDKIIELLGNSNRPIV
FILWGNNARMKKDLIKSKNALILESPHPSPFSANRGFFGCNHFIKTNDYLIDNGLEPIDWKIENI

Sequences:

>Translated_225_residues
MSVNIGNSWDELLKDEWNKDYYKKIRQVLIHDYKNYKVYPDMNFIFEALKLVAFEDCKVVILGQDPYHNPNQAHGLSFSV
KPDVKTPPSLINIYKELQNEFGYPIPNNGYLMKWAKQGVLLLNTSLTVIENKPNSHSKIGWQILTDKIIELLGNSNRPIV
FILWGNNARMKKDLIKSKNALILESPHPSPFSANRGFFGCNHFIKTNDYLIDNGLEPIDWKIENI
>Mature_224_residues
SVNIGNSWDELLKDEWNKDYYKKIRQVLIHDYKNYKVYPDMNFIFEALKLVAFEDCKVVILGQDPYHNPNQAHGLSFSVK
PDVKTPPSLINIYKELQNEFGYPIPNNGYLMKWAKQGVLLLNTSLTVIENKPNSHSKIGWQILTDKIIELLGNSNRPIVF
ILWGNNARMKKDLIKSKNALILESPHPSPFSANRGFFGCNHFIKTNDYLIDNGLEPIDWKIENI

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=222, Percent_Identity=47.2972972972973, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI6224979, Length=222, Percent_Identity=47.2972972972973, Blast_Score=209, Evalue=1e-54,
Organism=Escherichia coli, GI1788934, Length=215, Percent_Identity=46.9767441860465, Blast_Score=224, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17556304, Length=222, Percent_Identity=46.8468468468468, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6323620, Length=236, Percent_Identity=45.7627118644068, Blast_Score=198, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 26023; Mature: 25892

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNIGNSWDELLKDEWNKDYYKKIRQVLIHDYKNYKVYPDMNFIFEALKLVAFEDCKVV
CCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHEECCCEEE
ILGQDPYHNPNQAHGLSFSVKPDVKTPPSLINIYKELQNEFGYPIPNNGYLMKWAKQGVL
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEE
LLNTSLTVIENKPNSHSKIGWQILTDKIIELLGNSNRPIVFILWGNNARMKKDLIKSKNA
EEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCE
LILESPHPSPFSANRGFFGCNHFIKTNDYLIDNGLEPIDWKIENI
EEEECCCCCCCCCCCCEECCCCEEECCCEEECCCCCCCCEEECCC
>Mature Secondary Structure 
SVNIGNSWDELLKDEWNKDYYKKIRQVLIHDYKNYKVYPDMNFIFEALKLVAFEDCKVV
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHEECCCEEE
ILGQDPYHNPNQAHGLSFSVKPDVKTPPSLINIYKELQNEFGYPIPNNGYLMKWAKQGVL
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEE
LLNTSLTVIENKPNSHSKIGWQILTDKIIELLGNSNRPIVFILWGNNARMKKDLIKSKNA
EEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCE
LILESPHPSPFSANRGFFGCNHFIKTNDYLIDNGLEPIDWKIENI
EEEECCCCCCCCCCCCEECCCCEEECCCEEECCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA