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The map label for this gene is fur [H]

Identifier: 169824327

GI number: 169824327

Start: 695775

End: 696227

Strand: Direct

Name: fur [H]

Synonym: FMG_0630

Alternate gene names: 169824327

Gene position: 695775-696227 (Clockwise)

Preceding gene: 169824326

Following gene: 169824328

Centisome position: 38.71

GC content: 28.7

Gene sequence:

>453_bases
ATGAACATTGAAACATTAAAAACTAAACTAATCAATGCAGGATACAAAGTAACTAAACAAAGAGAAGTAATTTTTGAAGC
ATTGTTAGAAAATATGGATTCACACCTATCTCCGGAAGAATTAAACGAAATAGTAAGCAAAAAAGATCCGGAAATTGGTA
TAGCTACGGTTTATAGAACTTTATTAATTTTTGAAGAACTTAACTTGGTATATAAGTTAGATTTTGATGATAAAAGATAC
AGATATGAATTAGTGGATGAAGATGAAGATCACCATCATCACCATATTATATGCACTAATTGTGGTAAAGTTGATGAAGT
TAAGTATGATTTATTAGAAGGCATCGAAAAGCAAATTAGAAAAGATTACAACTTCGATATACAAAATCACGATGTAAAGT
TTTATGGGATATGTTCTGATTGCCAAGAGAAACTTAAAAATGAGGAGAAATAA

Upstream 100 bases:

>100_bases
ACGATGAACAAATTGAATTTATTGGATTAGAAAACGAAAATGAATTAAACGATGCTATCGAAGTATATGAAGATCTAATG
AATTCACAAAAGGAGCAATA

Downstream 100 bases:

>100_bases
ATGGCAAAAAAGAATATTGATAAATTAAAAGTTATTCCACTAGGAGGACTTAATGAAATAGGGAAAAATATGACAGTAGT
AGAATACAAAGATGATATTA

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNIETLKTKLINAGYKVTKQREVIFEALLENMDSHLSPEELNEIVSKKDPEIGIATVYRTLLIFEELNLVYKLDFDDKRY
RYELVDEDEDHHHHHIICTNCGKVDEVKYDLLEGIEKQIRKDYNFDIQNHDVKFYGICSDCQEKLKNEEK

Sequences:

>Translated_150_residues
MNIETLKTKLINAGYKVTKQREVIFEALLENMDSHLSPEELNEIVSKKDPEIGIATVYRTLLIFEELNLVYKLDFDDKRY
RYELVDEDEDHHHHHIICTNCGKVDEVKYDLLEGIEKQIRKDYNFDIQNHDVKFYGICSDCQEKLKNEEK
>Mature_150_residues
MNIETLKTKLINAGYKVTKQREVIFEALLENMDSHLSPEELNEIVSKKDPEIGIATVYRTLLIFEELNLVYKLDFDDKRY
RYELVDEDEDHHHHHIICTNCGKVDEVKYDLLEGIEKQIRKDYNFDIQNHDVKFYGICSDCQEKLKNEEK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=37.6811594202899, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17838; Mature: 17838

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIETLKTKLINAGYKVTKQREVIFEALLENMDSHLSPEELNEIVSKKDPEIGIATVYRT
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHH
LLIFEELNLVYKLDFDDKRYRYELVDEDEDHHHHHIICTNCGKVDEVKYDLLEGIEKQIR
HHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
KDYNFDIQNHDVKFYGICSDCQEKLKNEEK
HCCCCCCCCCCEEEEEEHHHHHHHHHCCCC
>Mature Secondary Structure
MNIETLKTKLINAGYKVTKQREVIFEALLENMDSHLSPEELNEIVSKKDPEIGIATVYRT
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHH
LLIFEELNLVYKLDFDDKRYRYELVDEDEDHHHHHIICTNCGKVDEVKYDLLEGIEKQIR
HHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
KDYNFDIQNHDVKFYGICSDCQEKLKNEEK
HCCCCCCCCCCEEEEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]