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The map label for this gene is asnC

Identifier: 169824319

GI number: 169824319

Start: 686390

End: 687775

Strand: Direct

Name: asnC

Synonym: FMG_0622

Alternate gene names: 169824319

Gene position: 686390-687775 (Clockwise)

Preceding gene: 169824318

Following gene: 169824320

Centisome position: 38.18

GC content: 32.03

Gene sequence:

>1386_bases
ATGATATTAATTAAAGATTTGATTAAAGATTACGAAAAGTATTCTGACAAAGAAGTTGAAGTTGGAGGTTGGATTAAAAA
CTCAAGATTTAGTAAAAATGTTGGTTTTATTGAACTAAATGACGGAACTTTCTTCAATCCTGTTCAAATTGTTGTAGGAA
AAGATAATGAGGATTTTGAAAGGGCTGAAAAGTTAAAACTAAGCTCTGCAATTATTGTTGTAGGTAAATTAGTTTTGACT
CCAAATTCTAAGCAACCATTTGAAATTCAAGCGTCAAAAGTTATTGTAGAAGGAGAATCTACTGATGATTATCCACTACA
AAAGAAAAGACATACATTTGAATTTTTGAGAACAATTTTACACTTAAGACCAAGAACAAATACATTTAATGCTGTATTTA
GAGTTAGAAGCAGATTAGCATTTGCTATTCATAAATTCTTTAATGAAAGAGGATTCGTTTATGTTCATACTCCAATTATA
ACAGGCAGTGATGCTGAAGGTGCTGGAGAAATGTTCAGAGTTACAACATTGGATTTGGATAATCTTCCAAAAGATGATGA
CGGAAATGTTGATTTCACACAAGATTTCTTCTCAAAATCTACTAACTTAACTGTAAGTGGTCAATTGCAAGCAGAAGCTT
ACGCACTAGCTTTCAGAAATGTATATACATTTGGACCAACTTTTAGAAGTGAACATTCTAATACTCCTAGACATGCGGCA
GAATTTTGGATGATGGAACCTGAAATATGTTTCGCAGATTTGGATGATGTGTGTAGCTTAGCCGAAGATATGGTTAGATA
TATCATAAAAGATGTTATGGAAAATTGTGAAGAGGAAATTAAATTCTTTAATAGTTTTGTAGACAAGAACTTGATTGAAA
GATTGACAAAAGTTGCAAACAAATCATTCAAAAAATTAACTTATACTGAAGCTATTGATATTCTAAAAAAATCAGGAGAA
AAGTTTGAATACCCTGTTAAATGGGGAATGGATCTACAAACAGAACACGAAAAATATTTGAGTGAAAAAGTTGTTGACGG
TCCAGTGTTTGTTACTGATTATCCAAAAGAAATCAAAGCTTTTTACATGAGACTTAATGACGACAAAAAAACAGTTGCTG
CAACTGACCTTTTAGTTCCAGGAATTGGTGAGTTAATTGGTGGAAGCCAAAGAGAAGAAAGATTTGAATTATTGGATCAA
AAAATGGATGAGCTAGGTTTCAACAAAGAAGAATATAAATGGTATCTTGATTTAAGAAAATACGGTGGGGTTAAACACGG
CGGATTTGGACTTGGATTTGAAAGAATGGTAATGTACATGACAGGAATGTCAAATATAAGAGATGTCATTCCGTTCCCAA
GAACTGTTGGACATTGTGAATATTAA

Upstream 100 bases:

>100_bases
ATCAACAATACTTACCTGACGAATTGAAAAATCAAAAATATTACGATCCAAAAGATATTGGATTTGAAAGCAAAATATAT
AAAAAAATAAGGAGTAAAGA

Downstream 100 bases:

>100_bases
TATTGTATTTAATTCTTTGATGTGGTATCATAGTAATAAGTTTTTATAATAATATTTGAATAAAAGTAGTAAATAATTAA
AAAATTTCAGAGAGTTGATG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MILIKDLIKDYEKYSDKEVEVGGWIKNSRFSKNVGFIELNDGTFFNPVQIVVGKDNEDFERAEKLKLSSAIIVVGKLVLT
PNSKQPFEIQASKVIVEGESTDDYPLQKKRHTFEFLRTILHLRPRTNTFNAVFRVRSRLAFAIHKFFNERGFVYVHTPII
TGSDAEGAGEMFRVTTLDLDNLPKDDDGNVDFTQDFFSKSTNLTVSGQLQAEAYALAFRNVYTFGPTFRSEHSNTPRHAA
EFWMMEPEICFADLDDVCSLAEDMVRYIIKDVMENCEEEIKFFNSFVDKNLIERLTKVANKSFKKLTYTEAIDILKKSGE
KFEYPVKWGMDLQTEHEKYLSEKVVDGPVFVTDYPKEIKAFYMRLNDDKKTVAATDLLVPGIGELIGGSQREERFELLDQ
KMDELGFNKEEYKWYLDLRKYGGVKHGGFGLGFERMVMYMTGMSNIRDVIPFPRTVGHCEY

Sequences:

>Translated_461_residues
MILIKDLIKDYEKYSDKEVEVGGWIKNSRFSKNVGFIELNDGTFFNPVQIVVGKDNEDFERAEKLKLSSAIIVVGKLVLT
PNSKQPFEIQASKVIVEGESTDDYPLQKKRHTFEFLRTILHLRPRTNTFNAVFRVRSRLAFAIHKFFNERGFVYVHTPII
TGSDAEGAGEMFRVTTLDLDNLPKDDDGNVDFTQDFFSKSTNLTVSGQLQAEAYALAFRNVYTFGPTFRSEHSNTPRHAA
EFWMMEPEICFADLDDVCSLAEDMVRYIIKDVMENCEEEIKFFNSFVDKNLIERLTKVANKSFKKLTYTEAIDILKKSGE
KFEYPVKWGMDLQTEHEKYLSEKVVDGPVFVTDYPKEIKAFYMRLNDDKKTVAATDLLVPGIGELIGGSQREERFELLDQ
KMDELGFNKEEYKWYLDLRKYGGVKHGGFGLGFERMVMYMTGMSNIRDVIPFPRTVGHCEY
>Mature_461_residues
MILIKDLIKDYEKYSDKEVEVGGWIKNSRFSKNVGFIELNDGTFFNPVQIVVGKDNEDFERAEKLKLSSAIIVVGKLVLT
PNSKQPFEIQASKVIVEGESTDDYPLQKKRHTFEFLRTILHLRPRTNTFNAVFRVRSRLAFAIHKFFNERGFVYVHTPII
TGSDAEGAGEMFRVTTLDLDNLPKDDDGNVDFTQDFFSKSTNLTVSGQLQAEAYALAFRNVYTFGPTFRSEHSNTPRHAA
EFWMMEPEICFADLDDVCSLAEDMVRYIIKDVMENCEEEIKFFNSFVDKNLIERLTKVANKSFKKLTYTEAIDILKKSGE
KFEYPVKWGMDLQTEHEKYLSEKVVDGPVFVTDYPKEIKAFYMRLNDDKKTVAATDLLVPGIGELIGGSQREERFELLDQ
KMDELGFNKEEYKWYLDLRKYGGVKHGGFGLGFERMVMYMTGMSNIRDVIPFPRTVGHCEY

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=455, Percent_Identity=41.978021978022, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI4758762, Length=476, Percent_Identity=27.1008403361345, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI45439306, Length=339, Percent_Identity=29.2035398230088, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1787161, Length=447, Percent_Identity=56.8232662192394, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI1789256, Length=480, Percent_Identity=26.25, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790571, Length=482, Percent_Identity=25.7261410788382, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788173, Length=150, Percent_Identity=32, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17556372, Length=439, Percent_Identity=32.3462414578588, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71984122, Length=463, Percent_Identity=28.2937365010799, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17551876, Length=349, Percent_Identity=27.7936962750716, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=480, Percent_Identity=39.1666666666667, Blast_Score=338, Evalue=8e-94,
Organism=Saccharomyces cerevisiae, GI6321807, Length=469, Percent_Identity=27.7185501066098, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=484, Percent_Identity=27.8925619834711, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19922416, Length=447, Percent_Identity=36.0178970917226, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI19921528, Length=468, Percent_Identity=27.3504273504274, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI17136276, Length=347, Percent_Identity=27.0893371757925, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53189; Mature: 53189

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIKDLIKDYEKYSDKEVEVGGWIKNSRFSKNVGFIELNDGTFFNPVQIVVGKDNEDFE
CEEHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCEEEECCCCEECCEEEEEECCCHHHH
RAEKLKLSSAIIVVGKLVLTPNSKQPFEIQASKVIVEGESTDDYPLQKKRHTFEFLRTIL
HHHHHHHHHHEEEEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
HLRPRTNTFNAVFRVRSRLAFAIHKFFNERGFVYVHTPIITGSDAEGAGEMFRVTTLDLD
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEECCCCCCCCCEEEEEEEECC
NLPKDDDGNVDFTQDFFSKSTNLTVSGQLQAEAYALAFRNVYTFGPTFRSEHSNTPRHAA
CCCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
EFWMMEPEICFADLDDVCSLAEDMVRYIIKDVMENCEEEIKFFNSFVDKNLIERLTKVAN
HHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSFKKLTYTEAIDILKKSGEKFEYPVKWGMDLQTEHEKYLSEKVVDGPVFVTDYPKEIKA
HHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHHH
FYMRLNDDKKTVAATDLLVPGIGELIGGSQREERFELLDQKMDELGFNKEEYKWYLDLRK
HHHHCCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEHHH
YGGVKHGGFGLGFERMVMYMTGMSNIRDVIPFPRTVGHCEY
HCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MILIKDLIKDYEKYSDKEVEVGGWIKNSRFSKNVGFIELNDGTFFNPVQIVVGKDNEDFE
CEEHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCEEEECCCCEECCEEEEEECCCHHHH
RAEKLKLSSAIIVVGKLVLTPNSKQPFEIQASKVIVEGESTDDYPLQKKRHTFEFLRTIL
HHHHHHHHHHEEEEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
HLRPRTNTFNAVFRVRSRLAFAIHKFFNERGFVYVHTPIITGSDAEGAGEMFRVTTLDLD
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEECCCCCCCCCEEEEEEEECC
NLPKDDDGNVDFTQDFFSKSTNLTVSGQLQAEAYALAFRNVYTFGPTFRSEHSNTPRHAA
CCCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
EFWMMEPEICFADLDDVCSLAEDMVRYIIKDVMENCEEEIKFFNSFVDKNLIERLTKVAN
HHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSFKKLTYTEAIDILKKSGEKFEYPVKWGMDLQTEHEKYLSEKVVDGPVFVTDYPKEIKA
HHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHHH
FYMRLNDDKKTVAATDLLVPGIGELIGGSQREERFELLDQKMDELGFNKEEYKWYLDLRK
HHHHCCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEHHH
YGGVKHGGFGLGFERMVMYMTGMSNIRDVIPFPRTVGHCEY
HCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]