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The map label for this gene is exeF [H]

Identifier: 169823948

GI number: 169823948

Start: 295920

End: 297011

Strand: Direct

Name: exeF [H]

Synonym: FMG_0251

Alternate gene names: 169823948

Gene position: 295920-297011 (Clockwise)

Preceding gene: 169823947

Following gene: 169823950

Centisome position: 16.46

GC content: 31.41

Gene sequence:

>1092_bases
ATGAAGATTGACAGTTTGCTAAAAGAAGACAGTGTATTAAAAAAAGAAATAAACTTCAAGGCTTCCAAGAAAAAGCTGTT
TTTGTTTCTGAGACAATTTTCAATTCTTTTGAATGCGAAGATTCCAATCATAGAAATAATCAATCTACTCAAGGAACAAA
AAGAATTCAAACAATTAAAACCCAGCTTGGACAAAGTTTCTGAGAATTTGAATAACGGGTTGAGCGTGTCGGAAAGTTTC
TGTGGCGACAAAAACTTCGACATGTTTTTTACATCGATGATGAAACTCGGAGAAGAAAGTGGTAGACTCGACAAAGTGGT
CTACGATTTGAGCAAATACTACGAGAGAACCTACGATATTAACAAAAAAATTCAAAATGCAATGATTTATCCTATTATTT
TGACTGTTACGGGAATTGTAATGTTGATATTTATGCTCAAAAACGTCATTCCAACATTCGTGGATTTGTTTGAAAGCTCT
GACATGGTGCTTCCATTGTCTACAAGAATTCTAATTTCAGTATCAAATACTATAAATGAAAAAGGATTATTGATTTTAAT
TATTTTAGTTCTAATAATTGCGGGACTTATCATAGCTTATCGAAAAACAAAATTTGGATATTACCTGGACAAATTCAAAA
CTACAAATCCGATTTTTGGAAAACAAAGACAAATAGTAATCTCATCTGAAATTGCGAGAAGTTTAAGCATAACTCACAAA
AACTCCATGACAATTCTTGATGGACTGATCATAATTCAAAAATCCATGAAAAACAAATACTACAAACAAGAACTTTCCGA
TATTTTCAAAGAAATAGAATCTGGAGAATTTACACTTGAAGAAGCCTTCAATAAAAGAAAAATAACGCCACAAGTGTTCA
ATTCAATGTTAAAAGTTGCAGAAAATACTGGGGAATTGGGAGATATTTTCGAGAAATTATCTGAATTTTACGACGGGGAA
GTGGAATATGCAATTAAATCGTTCATAAGCATATTAGAGCCAATGCTTATAATCTTCATGGCAATAATCGTTGGATTTAT
CGTAATATCCATCACTATTCCTATGTTTGATGTGATAAATTCGTTTAATTAA

Upstream 100 bases:

>100_bases
AACTACGGAGAAGAAAATAACATCGACAGTTTATTCAAAAAAGCTTTGATACAAGTAGCACTTGGAAACACTTCATTTGA
CGAAGCGATGAGGTTGTACA

Downstream 100 bases:

>100_bases
AAAACTGTGGTATAAAGTATTAACGCTCATGCACGAACATCTAGACTACAAAAATTGTTGATTTCTAAATCTTAAAATCC
TAAAATCGTAAGCACGCTTC

Product: putative pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKIDSLLKEDSVLKKEINFKASKKKLFLFLRQFSILLNAKIPIIEIINLLKEQKEFKQLKPSLDKVSENLNNGLSVSESF
CGDKNFDMFFTSMMKLGEESGRLDKVVYDLSKYYERTYDINKKIQNAMIYPIILTVTGIVMLIFMLKNVIPTFVDLFESS
DMVLPLSTRILISVSNTINEKGLLILIILVLIIAGLIIAYRKTKFGYYLDKFKTTNPIFGKQRQIVISSEIARSLSITHK
NSMTILDGLIIIQKSMKNKYYKQELSDIFKEIESGEFTLEEAFNKRKITPQVFNSMLKVAENTGELGDIFEKLSEFYDGE
VEYAIKSFISILEPMLIIFMAIIVGFIVISITIPMFDVINSFN

Sequences:

>Translated_363_residues
MKIDSLLKEDSVLKKEINFKASKKKLFLFLRQFSILLNAKIPIIEIINLLKEQKEFKQLKPSLDKVSENLNNGLSVSESF
CGDKNFDMFFTSMMKLGEESGRLDKVVYDLSKYYERTYDINKKIQNAMIYPIILTVTGIVMLIFMLKNVIPTFVDLFESS
DMVLPLSTRILISVSNTINEKGLLILIILVLIIAGLIIAYRKTKFGYYLDKFKTTNPIFGKQRQIVISSEIARSLSITHK
NSMTILDGLIIIQKSMKNKYYKQELSDIFKEIESGEFTLEEAFNKRKITPQVFNSMLKVAENTGELGDIFEKLSEFYDGE
VEYAIKSFISILEPMLIIFMAIIVGFIVISITIPMFDVINSFN
>Mature_363_residues
MKIDSLLKEDSVLKKEINFKASKKKLFLFLRQFSILLNAKIPIIEIINLLKEQKEFKQLKPSLDKVSENLNNGLSVSESF
CGDKNFDMFFTSMMKLGEESGRLDKVVYDLSKYYERTYDINKKIQNAMIYPIILTVTGIVMLIFMLKNVIPTFVDLFESS
DMVLPLSTRILISVSNTINEKGLLILIILVLIIAGLIIAYRKTKFGYYLDKFKTTNPIFGKQRQIVISSEIARSLSITHK
NSMTILDGLIIIQKSMKNKYYKQELSDIFKEIESGEFTLEEAFNKRKITPQVFNSMLKVAENTGELGDIFEKLSEFYDGE
VEYAIKSFISILEPMLIIFMAIIVGFIVISITIPMFDVINSFN

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=349, Percent_Identity=27.5071633237822, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786295, Length=336, Percent_Identity=23.8095238095238, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR011850
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 41686; Mature: 41686

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDSLLKEDSVLKKEINFKASKKKLFLFLRQFSILLNAKIPIIEIINLLKEQKEFKQLK
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PSLDKVSENLNNGLSVSESFCGDKNFDMFFTSMMKLGEESGRLDKVVYDLSKYYERTYDI
CCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
NKKIQNAMIYPIILTVTGIVMLIFMLKNVIPTFVDLFESSDMVLPLSTRILISVSNTINE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCC
KGLLILIILVLIIAGLIIAYRKTKFGYYLDKFKTTNPIFGKQRQIVISSEIARSLSITHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHCCC
NSMTILDGLIIIQKSMKNKYYKQELSDIFKEIESGEFTLEEAFNKRKITPQVFNSMLKVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCCHHHHHHHHHHH
ENTGELGDIFEKLSEFYDGEVEYAIKSFISILEPMLIIFMAIIVGFIVISITIPMFDVIN
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFN
CCC
>Mature Secondary Structure
MKIDSLLKEDSVLKKEINFKASKKKLFLFLRQFSILLNAKIPIIEIINLLKEQKEFKQLK
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PSLDKVSENLNNGLSVSESFCGDKNFDMFFTSMMKLGEESGRLDKVVYDLSKYYERTYDI
CCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
NKKIQNAMIYPIILTVTGIVMLIFMLKNVIPTFVDLFESSDMVLPLSTRILISVSNTINE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCC
KGLLILIILVLIIAGLIIAYRKTKFGYYLDKFKTTNPIFGKQRQIVISSEIARSLSITHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHCCC
NSMTILDGLIIIQKSMKNKYYKQELSDIFKEIESGEFTLEEAFNKRKITPQVFNSMLKVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCCHHHHHHHHHHH
ENTGELGDIFEKLSEFYDGEVEYAIKSFISILEPMLIIFMAIIVGFIVISITIPMFDVIN
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1640836 [H]